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The map label for this gene is ybdR [H]

Identifier: 45657235

GI number: 45657235

Start: 1671042

End: 1672070

Strand: Reverse

Name: ybdR [H]

Synonym: LIC11357

Alternate gene names: 45657235

Gene position: 1672070-1671042 (Counterclockwise)

Preceding gene: 45657237

Following gene: 45657231

Centisome position: 39.09

GC content: 40.82

Gene sequence:

>1029_bases
ATGAAACGAATCGTATTCAAAAAAAAGCATATATTGGAATGGGAAAACGTTCCCGAACCAAAAATTCAAGGAATCAACCA
AGCAATTGTAAAACCAATCGCGGTTTCGCGTTGTGATCTGGATCTTCCGATAGTAAACGGTTATACTTTATTTAGACCGG
GAATTCCAATCGGTCATGAGTTCGTAGGAATGATCGAAGAAACGAGTCCTGAAATCGCAAACCAATATCCGAAAGGAACC
AAGGTAATCATTCCGTTTCAAATTTCCTGTGGAATTTGTCCAGATTGTACACTAGGACGTTCCAAGGCTTGTACTTCGGT
CCCTTACGCAAGTCATTACGGAATGGGACCTTCCGCAAAAGAATTCGGCGGTGCCTTGTCAGAAAAAATTTGGATTCCAT
TCGCCAAACAGATGTTAATCCCCATGCCTTCGGATATGGACGTGATCTCACTCGCTTCGATCAGCGACAATATAGTGGAA
GCGTGGAAATTGGTAGGACAATGGCTGGAGAAAAAACCGAATTCTCCTGTAATGATTTTGGGAGGTTTAGCTTCAAGTAT
CGGTTTGTATTCCGCTTCTCTCGCAGTAGGAATGGGTTCTTCCGAAGTTTTGTATCTGGACAACGATTCAGAAAGACTTA
AAATTGCGGAAAGCCTAGGTGCTAAAGCGGTTTCGTATTCCGTTCTTCCCAAGGCTTGGGAAAGAAAATTTCCCTTAATC
GCGGATTGTCACGGTTTGAAGGAAGGAATGGATTTCGCATTAAAATCTCTTTCTACGGAAGGGATCTATGGTTCTGCATC
CATTTTCTGGACAAATAAATTAGAAATTCCTTATTTAGATTTATATAATACTGGAGCAACCTTGAAGATTGGAAGAGTAG
ACTCAAGGGAATATATTCCGCATATCCTAAAAAAGATTTCTGAAAAAAAGATTAAACCAGAAAAAATTGTGACCAAAATC
TGTTCTTTCGAAGAAGCTACAGAAGCCTGGCTCGAACCGGCGATCAAGTTGGTGGTTAAAATGGACTGA

Upstream 100 bases:

>100_bases
TCACGTGTTCGGCATAAGAAATATAATGTGATTCTTAATCTTAAGAATTAAAATATAGTATCCATATTTCAATATTCTTA
TTAAAGTAGTTATGTAATCT

Downstream 100 bases:

>100_bases
ATCACATTCCAATTTCTGAATCAACCCAACTAACCAGTCCACAAAAGTCCGCTTTTTTTAGTTTTTCTATTCTATCTAGA
ATAGATTGGGCTTCCAGTGA

Product: alcohol dehydrogenase

Products: aldehyde; ketone; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MKRIVFKKKHILEWENVPEPKIQGINQAIVKPIAVSRCDLDLPIVNGYTLFRPGIPIGHEFVGMIEETSPEIANQYPKGT
KVIIPFQISCGICPDCTLGRSKACTSVPYASHYGMGPSAKEFGGALSEKIWIPFAKQMLIPMPSDMDVISLASISDNIVE
AWKLVGQWLEKKPNSPVMILGGLASSIGLYSASLAVGMGSSEVLYLDNDSERLKIAESLGAKAVSYSVLPKAWERKFPLI
ADCHGLKEGMDFALKSLSTEGIYGSASIFWTNKLEIPYLDLYNTGATLKIGRVDSREYIPHILKKISEKKIKPEKIVTKI
CSFEEATEAWLEPAIKLVVKMD

Sequences:

>Translated_342_residues
MKRIVFKKKHILEWENVPEPKIQGINQAIVKPIAVSRCDLDLPIVNGYTLFRPGIPIGHEFVGMIEETSPEIANQYPKGT
KVIIPFQISCGICPDCTLGRSKACTSVPYASHYGMGPSAKEFGGALSEKIWIPFAKQMLIPMPSDMDVISLASISDNIVE
AWKLVGQWLEKKPNSPVMILGGLASSIGLYSASLAVGMGSSEVLYLDNDSERLKIAESLGAKAVSYSVLPKAWERKFPLI
ADCHGLKEGMDFALKSLSTEGIYGSASIFWTNKLEIPYLDLYNTGATLKIGRVDSREYIPHILKKISEKKIKPEKIVTKI
CSFEEATEAWLEPAIKLVVKMD
>Mature_342_residues
MKRIVFKKKHILEWENVPEPKIQGINQAIVKPIAVSRCDLDLPIVNGYTLFRPGIPIGHEFVGMIEETSPEIANQYPKGT
KVIIPFQISCGICPDCTLGRSKACTSVPYASHYGMGPSAKEFGGALSEKIWIPFAKQMLIPMPSDMDVISLASISDNIVE
AWKLVGQWLEKKPNSPVMILGGLASSIGLYSASLAVGMGSSEVLYLDNDSERLKIAESLGAKAVSYSVLPKAWERKFPLI
ADCHGLKEGMDFALKSLSTEGIYGSASIFWTNKLEIPYLDLYNTGATLKIGRVDSREYIPHILKKISEKKIKPEKIVTKI
CSFEEATEAWLEPAIKLVVKMD

Specific function: Unknown

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786825, Length=381, Percent_Identity=23.8845144356955, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788407, Length=225, Percent_Identity=28.4444444444444, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: 1.1.1.1

Molecular weight: Translated: 37721; Mature: 37721

Theoretical pI: Translated: 8.03; Mature: 8.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRIVFKKKHILEWENVPEPKIQGINQAIVKPIAVSRCDLDLPIVNGYTLFRPGIPIGHE
CCCCEECHHHHCCCCCCCCHHHHCCHHHHHHHHHHEECCCCCEEECCEEEECCCCCCCHH
FVGMIEETSPEIANQYPKGTKVIIPFQISCGICPDCTLGRSKACTSVPYASHYGMGPSAK
HHHHHHHCCCHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHCCCCCCHH
EFGGALSEKIWIPFAKQMLIPMPSDMDVISLASISDNIVEAWKLVGQWLEKKPNSPVMIL
HHCCHHHCCEECCCHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
GGLASSIGLYSASLAVGMGSSEVLYLDNDSERLKIAESLGAKAVSYSVLPKAWERKFPLI
CCHHHHHHHHHHHHEEECCCCCEEEEECCCCHHHHHHHHCCHHEEHHHCCHHHHCCCCCH
ADCHGLKEGMDFALKSLSTEGIYGSASIFWTNKLEIPYLDLYNTGATLKIGRVDSREYIP
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCEEEEECCCCEEEEECCCCHHHHH
HILKKISEKKIKPEKIVTKICSFEEATEAWLEPAIKLVVKMD
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECC
>Mature Secondary Structure
MKRIVFKKKHILEWENVPEPKIQGINQAIVKPIAVSRCDLDLPIVNGYTLFRPGIPIGHE
CCCCEECHHHHCCCCCCCCHHHHCCHHHHHHHHHHEECCCCCEEECCEEEECCCCCCCHH
FVGMIEETSPEIANQYPKGTKVIIPFQISCGICPDCTLGRSKACTSVPYASHYGMGPSAK
HHHHHHHCCCHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHCCCCCCHH
EFGGALSEKIWIPFAKQMLIPMPSDMDVISLASISDNIVEAWKLVGQWLEKKPNSPVMIL
HHCCHHHCCEECCCHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
GGLASSIGLYSASLAVGMGSSEVLYLDNDSERLKIAESLGAKAVSYSVLPKAWERKFPLI
CCHHHHHHHHHHHHEEECCCCCEEEEECCCCHHHHHHHHCCHHEEHHHCCHHHHCCCCCH
ADCHGLKEGMDFALKSLSTEGIYGSASIFWTNKLEIPYLDLYNTGATLKIGRVDSREYIP
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCEEEEECCCCEEEEECCCCHHHHH
HILKKISEKKIKPEKIVTKICSFEEATEAWLEPAIKLVVKMD
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: alcohol; NAD+

Specific reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]