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The map label for this gene is gph

Identifier: 45657182

GI number: 45657182

Start: 1609798

End: 1610472

Strand: Reverse

Name: gph

Synonym: LIC11302

Alternate gene names: 45657182

Gene position: 1610472-1609798 (Counterclockwise)

Preceding gene: 45657186

Following gene: 45657181

Centisome position: 37.65

GC content: 37.93

Gene sequence:

>675_bases
ATGACTGTATTTTCAGTAGAATCTCTCCAAGCCCTTGCGTTCGATGTAGACGGTACTCTTTTTTCGTCTGAAGGGATCAT
TCTTGAAGTCTACCGAGATTCGATTCTAAATTTTTCCAAGACCTCCGGAATCCAAATCGAACTTCCTTCTCGAGATCGAA
TTATGGCAGAAATCGGTAAACCGGTTAAAACCATATTCTTCAACCTTCTTCCCCAGCTAAATGAAGAACAAAGAGACAGC
ATCTCCGATAGTGTGCTTCGTTTTCTTTGCGATAGAATTAAAAAAGGAGAAGGAGAATTTTATCCCAACGTTTTGGAAAC
TATAGAAATCCTGGCTCAAAAAGGTTATCGTATTTTAGCCGCCTCAAACGGAAGAAAACCTTATATCCAAACCATACTTG
AAGTTTCCGGAATTCTTCCTAAATTTGAACCGATTTTAGTTTTAGACAACAAACGCATCCGAACCAAAGCAGAAATTTTA
GAAGAGTATATAAAACTCTATCATCTAAAACCAAATCAAATTCTAATGATTGGAGACAGACTTTCCGATCATGAAGCCGC
CAGACAAAACGGTTGTCCTTTTGCATTTTGTTCCTATGGACATGCTCCGGAAGGAGAAATTCCAGACTTCGATTTAAAAC
TTAAAAACATTTCAGATTTGAACGAAGTACTCTGA

Upstream 100 bases:

>100_bases
GAATGGGAAGTATTCATTCGGTTGTTCCTATTTTCTTCGAGTCCGGGGAAAATCAAGCAAAGGTTGCCAAAAGGATTCGT
TTTCTAAAACTGTCCTTAGA

Downstream 100 bases:

>100_bases
TTTTTACCTGCATAGAATCCGTTTTTTTTCCGAAAATGAAAGTGTGCCGGATTCCGAAAAAAGAAAAAATATCATTTTCA
TTCTCACCGGAATTATTTTT

Product: phosphoglycolate phosphatase

Products: glycolate; phosphate

Alternate protein names: Phosphatase; Haloacid Dehalogenase-Like Hydrolase; Hydrolase; Hydrolase Haloacid Dehalogenase-Like Family; MTA/SAH Nucleosidase C-Terminal Region; 5-Methylthioadenosine/S-Adenosylhomocysteine Nucleosidase; Haloacid Dehalogenase Domain-Containing Protein Hydrolase; Phosphoglycolate Phosphatase; Phosphatase HAD Family

Number of amino acids: Translated: 224; Mature: 223

Protein sequence:

>224_residues
MTVFSVESLQALAFDVDGTLFSSEGIILEVYRDSILNFSKTSGIQIELPSRDRIMAEIGKPVKTIFFNLLPQLNEEQRDS
ISDSVLRFLCDRIKKGEGEFYPNVLETIEILAQKGYRILAASNGRKPYIQTILEVSGILPKFEPILVLDNKRIRTKAEIL
EEYIKLYHLKPNQILMIGDRLSDHEAARQNGCPFAFCSYGHAPEGEIPDFDLKLKNISDLNEVL

Sequences:

>Translated_224_residues
MTVFSVESLQALAFDVDGTLFSSEGIILEVYRDSILNFSKTSGIQIELPSRDRIMAEIGKPVKTIFFNLLPQLNEEQRDS
ISDSVLRFLCDRIKKGEGEFYPNVLETIEILAQKGYRILAASNGRKPYIQTILEVSGILPKFEPILVLDNKRIRTKAEIL
EEYIKLYHLKPNQILMIGDRLSDHEAARQNGCPFAFCSYGHAPEGEIPDFDLKLKNISDLNEVL
>Mature_223_residues
TVFSVESLQALAFDVDGTLFSSEGIILEVYRDSILNFSKTSGIQIELPSRDRIMAEIGKPVKTIFFNLLPQLNEEQRDSI
SDSVLRFLCDRIKKGEGEFYPNVLETIEILAQKGYRILAASNGRKPYIQTILEVSGILPKFEPILVLDNKRIRTKAEILE
EYIKLYHLKPNQILMIGDRLSDHEAARQNGCPFAFCSYGHAPEGEIPDFDLKLKNISDLNEVL

Specific function: Unknown

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.1.3.18

Molecular weight: Translated: 25410; Mature: 25278

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVFSVESLQALAFDVDGTLFSSEGIILEVYRDSILNFSKTSGIQIELPSRDRIMAEIGK
CCEECHHHHHHHEEECCCEEECCCCEEEEEEHHHHHCCCCCCCEEEEECCCHHHHHHHCC
PVKTIFFNLLPQLNEEQRDSISDSVLRFLCDRIKKGEGEFYPNVLETIEILAQKGYRILA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEE
ASNGRKPYIQTILEVSGILPKFEPILVLDNKRIRTKAEILEEYIKLYHLKPNQILMIGDR
ECCCCCHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCEEEECCC
LSDHEAARQNGCPFAFCSYGHAPEGEIPDFDLKLKNISDLNEVL
CCCHHHHHHCCCCEEEECCCCCCCCCCCCCCEEECCHHHHHHCC
>Mature Secondary Structure 
TVFSVESLQALAFDVDGTLFSSEGIILEVYRDSILNFSKTSGIQIELPSRDRIMAEIGK
CEECHHHHHHHEEECCCEEECCCCEEEEEEHHHHHCCCCCCCEEEEECCCHHHHHHHCC
PVKTIFFNLLPQLNEEQRDSISDSVLRFLCDRIKKGEGEFYPNVLETIEILAQKGYRILA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEE
ASNGRKPYIQTILEVSGILPKFEPILVLDNKRIRTKAEILEEYIKLYHLKPNQILMIGDR
ECCCCCHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCEEEECCC
LSDHEAARQNGCPFAFCSYGHAPEGEIPDFDLKLKNISDLNEVL
CCCHHHHHHCCCCEEEECCCCCCCCCCCCCCEEECCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Mg2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.57 {phosphoglycolate}} [C]

Substrates: 2-phosphoglycolate; H2O

Specific reaction: 2-phosphoglycolate + H2O = glycolate + phosphate

General reaction: Additional information:

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA