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The map label for this gene is cpt

Identifier: 45656871

GI number: 45656871

Start: 1188652

End: 1190172

Strand: Reverse

Name: cpt

Synonym: LIC10983

Alternate gene names: 45656871

Gene position: 1190172-1188652 (Counterclockwise)

Preceding gene: 45656874

Following gene: 45656870

Centisome position: 27.83

GC content: 36.16

Gene sequence:

>1521_bases
ATGAAATCGTATCTTCCTTCAAACACCATATTTATAGTCTATATTTGTCTGTTTTTATTTGTTTCCTGTGCTGGTTTCTT
TCGTAAAAAGATTCCAAATTCTCCCTTAAACGATCCAAGAAAAATGATACTCGTTCGGATCGATCCAGGACGACTGGGAG
AATTTAAAGAAAAAACCGGAGGAAAGTATAACATCAGTTATCAAGAATCGGATTCTTATTATTCCGTAATCAATAAACAA
GACATAGATAAGTTCGGATTTCCATCTCCCGGAATTTCCGTCGTTAAACAATACTTACCATTTAAATATTATTCCGGCAA
TTATCAGGAATTGATCAACGAAAGATTTACAAGTCTTGAAGATCTAAAAAAAGGTTATAAGGATAACATATTAAATATTC
ATTATTTACTTGGAATCGCAAATTTATATTCGGAACAATCCAGAATGGAAGTGATCGGCAAAACCGCTAGAGGAAGAGAA
ATTCCGGCCCTACTTCTAACAAACACAACCACTCCAGACGAGGAAAAAATTTCCGTACTTTTTAACTGCGCTCACCACGC
AAACGAAGTTATATCCATTGAACACTGTTACGATATAATCTATTCCGTATTATCTAGACCAAAAGAATATCAGGAAATCC
TAAATAAGATGAAAATCTGGATTGTACCTATTGTCAATCCAGATGGCGCCAGACATTTTTGGCACGTATCTAACCTGATG
GGAAGAAAAAACGGTTATCCAGGTTCTGGTCCAGTAAACGACAAGTTAAATCCAGGAGTAGATATCAATCGCAATTATCC
GTTTTATTGGGGAAAAGCCGGAGGAGGATATTCTTCTTCTAATCCTTCTAACTATTTTTATAGAGGCCCCTCGCCAGGGT
CAGAATCAGAAACAAAAGCAATGATGGACCTTGCAAATCGGGAAAGGTTTGCGGCATCCATTAGCTATCATGCATATGCA
AATTGTCTGTTAATTCCATATTCGATCGATTCATTAAATAATCCGGAACCAGACGTGGCCAAGGAAATAGGAAAAAAAAT
CGCTGCTTCTGTGACTAGCTTAAATCCAGAAAAAGAATTCGAAGCAAAAAAAAATATCTATCCAATAGACGGAGTCGATC
AAGACTACTTCTACTTTGCACATGGAACTCTCGCTTATCTATTGGAAACCACACATCTCAACCCGGAATACAAGGAAGTG
GAAAAAGTAAACGTATCCTTGAGGAAGGCTTGGAACTTATTGTTAAACGAAGTTTTAGAAGGAAAAAAGATTTTTCTAAA
AATCACGGATGAATTCGGAACACCACTCGAAGCAAAAGTAGAAATCGAAAGAATAAAATACTTTCAGGAAGAAATTCGAG
TTTCTAATCCGATCAACGGTTTTTTCTTTCAACTGTTTCCAGATAGAAAGGAAACTAAAGTTAAAATTTCGAAAGAAGGT
TACGAACCGACAGAAATACAAACCAGACCAAACGGCAAATGGGAACCTCTAAAAATCGTACTTAAGAAAAATAGAATATA
A

Upstream 100 bases:

>100_bases
ATAGACTGAAAAACGAAACGGACAAATCAATCAAGTATTTAAAAAAATCTCTGGATTCTGAAAGCGATAAGAACAAACTA
GTTCCAATATTTTATAAAGA

Downstream 100 bases:

>100_bases
TGTTTCACATAAGACACGAAATTTATCTTATCCTCTGCACCTTGATATGGGGAGGAACCTTTACAATGACTATTTTCGGT
CTCAGAGACACTTCGCCTTC

Product: carboxypeptidase T

Products: NA

Alternate protein names: CPase SG; CPSG [H]

Number of amino acids: Translated: 506; Mature: 506

Protein sequence:

>506_residues
MKSYLPSNTIFIVYICLFLFVSCAGFFRKKIPNSPLNDPRKMILVRIDPGRLGEFKEKTGGKYNISYQESDSYYSVINKQ
DIDKFGFPSPGISVVKQYLPFKYYSGNYQELINERFTSLEDLKKGYKDNILNIHYLLGIANLYSEQSRMEVIGKTARGRE
IPALLLTNTTTPDEEKISVLFNCAHHANEVISIEHCYDIIYSVLSRPKEYQEILNKMKIWIVPIVNPDGARHFWHVSNLM
GRKNGYPGSGPVNDKLNPGVDINRNYPFYWGKAGGGYSSSNPSNYFYRGPSPGSESETKAMMDLANRERFAASISYHAYA
NCLLIPYSIDSLNNPEPDVAKEIGKKIAASVTSLNPEKEFEAKKNIYPIDGVDQDYFYFAHGTLAYLLETTHLNPEYKEV
EKVNVSLRKAWNLLLNEVLEGKKIFLKITDEFGTPLEAKVEIERIKYFQEEIRVSNPINGFFFQLFPDRKETKVKISKEG
YEPTEIQTRPNGKWEPLKIVLKKNRI

Sequences:

>Translated_506_residues
MKSYLPSNTIFIVYICLFLFVSCAGFFRKKIPNSPLNDPRKMILVRIDPGRLGEFKEKTGGKYNISYQESDSYYSVINKQ
DIDKFGFPSPGISVVKQYLPFKYYSGNYQELINERFTSLEDLKKGYKDNILNIHYLLGIANLYSEQSRMEVIGKTARGRE
IPALLLTNTTTPDEEKISVLFNCAHHANEVISIEHCYDIIYSVLSRPKEYQEILNKMKIWIVPIVNPDGARHFWHVSNLM
GRKNGYPGSGPVNDKLNPGVDINRNYPFYWGKAGGGYSSSNPSNYFYRGPSPGSESETKAMMDLANRERFAASISYHAYA
NCLLIPYSIDSLNNPEPDVAKEIGKKIAASVTSLNPEKEFEAKKNIYPIDGVDQDYFYFAHGTLAYLLETTHLNPEYKEV
EKVNVSLRKAWNLLLNEVLEGKKIFLKITDEFGTPLEAKVEIERIKYFQEEIRVSNPINGFFFQLFPDRKETKVKISKEG
YEPTEIQTRPNGKWEPLKIVLKKNRI
>Mature_506_residues
MKSYLPSNTIFIVYICLFLFVSCAGFFRKKIPNSPLNDPRKMILVRIDPGRLGEFKEKTGGKYNISYQESDSYYSVINKQ
DIDKFGFPSPGISVVKQYLPFKYYSGNYQELINERFTSLEDLKKGYKDNILNIHYLLGIANLYSEQSRMEVIGKTARGRE
IPALLLTNTTTPDEEKISVLFNCAHHANEVISIEHCYDIIYSVLSRPKEYQEILNKMKIWIVPIVNPDGARHFWHVSNLM
GRKNGYPGSGPVNDKLNPGVDINRNYPFYWGKAGGGYSSSNPSNYFYRGPSPGSESETKAMMDLANRERFAASISYHAYA
NCLLIPYSIDSLNNPEPDVAKEIGKKIAASVTSLNPEKEFEAKKNIYPIDGVDQDYFYFAHGTLAYLLETTHLNPEYKEV
EKVNVSLRKAWNLLLNEVLEGKKIFLKITDEFGTPLEAKVEIERIKYFQEEIRVSNPINGFFFQLFPDRKETKVKISKEG
YEPTEIQTRPNGKWEPLKIVLKKNRI

Specific function: Combines the specificities of mammalian Cpase A and B [H]

COG id: COG2866

COG function: function code E; Predicted carboxypeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M14 family [H]

Homologues:

Organism=Homo sapiens, GI54607080, Length=239, Percent_Identity=28.0334728033473, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI221316749, Length=249, Percent_Identity=29.718875502008, Blast_Score=84, Evalue=5e-16,
Organism=Homo sapiens, GI254540196, Length=288, Percent_Identity=26.0416666666667, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI61743916, Length=288, Percent_Identity=26.0416666666667, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI217416390, Length=188, Percent_Identity=30.8510638297872, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI188536067, Length=238, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI188536053, Length=199, Percent_Identity=32.1608040201005, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI188536051, Length=199, Percent_Identity=32.1608040201005, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI188536055, Length=199, Percent_Identity=32.1608040201005, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI4502997, Length=233, Percent_Identity=27.8969957081545, Blast_Score=69, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193207630, Length=322, Percent_Identity=24.8447204968944, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI25143424, Length=284, Percent_Identity=26.7605633802817, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71990283, Length=182, Percent_Identity=29.6703296703297, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI32563699, Length=182, Percent_Identity=29.6703296703297, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI193203290, Length=220, Percent_Identity=28.6363636363636, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI71990304, Length=270, Percent_Identity=27.7777777777778, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71990310, Length=270, Percent_Identity=27.7777777777778, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI212645216, Length=277, Percent_Identity=26.7148014440433, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI212645214, Length=277, Percent_Identity=26.7148014440433, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI32563693, Length=219, Percent_Identity=29.2237442922374, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI20129775, Length=246, Percent_Identity=29.2682926829268, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24586446, Length=246, Percent_Identity=29.2682926829268, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI28574373, Length=269, Percent_Identity=26.7657992565056, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI45550795, Length=240, Percent_Identity=28.75, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24639964, Length=206, Percent_Identity=27.6699029126214, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI28574958, Length=306, Percent_Identity=25.8169934640523, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI221330951, Length=259, Percent_Identity=27.7992277992278, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI21356641, Length=294, Percent_Identity=23.469387755102, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24660095, Length=256, Percent_Identity=26.5625, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24583124, Length=240, Percent_Identity=28.3333333333333, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24639970, Length=252, Percent_Identity=26.5873015873016, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI19922132, Length=184, Percent_Identity=27.7173913043478, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI85726410, Length=248, Percent_Identity=28.2258064516129, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI21356639, Length=152, Percent_Identity=32.8947368421053, Blast_Score=69, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24583126, Length=238, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI20129321, Length=225, Percent_Identity=26.6666666666667, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24642710, Length=145, Percent_Identity=33.1034482758621, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000834 [H]

Pfam domain/function: PF00246 Peptidase_M14 [H]

EC number: NA

Molecular weight: Translated: 58071; Mature: 58071

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSYLPSNTIFIVYICLFLFVSCAGFFRKKIPNSPLNDPRKMILVRIDPGRLGEFKEKTG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCHHHHCC
GKYNISYQESDSYYSVINKQDIDKFGFPSPGISVVKQYLPFKYYSGNYQELINERFTSLE
CEEEEEEECCCCHHHHHCCCCCHHCCCCCCCHHHHHHHCCCEECCCCHHHHHHHHHHHHH
DLKKGYKDNILNIHYLLGIANLYSEQSRMEVIGKTARGREIPALLLTNTTTPDEEKISVL
HHHCCHHCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHH
FNCAHHANEVISIEHCYDIIYSVLSRPKEYQEILNKMKIWIVPIVNPDGARHFWHVSNLM
HHHHHHCCCEEEHHHHHHHHHHHHCCCHHHHHHHHCCEEEEEEEECCCCCCHHHHHHHHH
GRKNGYPGSGPVNDKLNPGVDINRNYPFYWGKAGGGYSSSNPSNYFYRGPSPGSESETKA
HCCCCCCCCCCCCCCCCCCEECCCCCCEEECCCCCCCCCCCCCCEEEECCCCCCHHHHHH
MMDLANRERFAASISYHAYANCLLIPYSIDSLNNPEPDVAKEIGKKIAASVTSLNPEKEF
HHHHHHHHHHHHEEEHEEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHH
EAKKNIYPIDGVDQDYFYFAHGTLAYLLETTHLNPEYKEVEKVNVSLRKAWNLLLNEVLE
HHHCCCCCCCCCCCCEEEEECCHHEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
GKKIFLKITDEFGTPLEAKVEIERIKYFQEEIRVSNPINGFFFQLFPDRKETKVKISKEG
CCEEEEEEECCCCCCCCCEEHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEECCC
YEPTEIQTRPNGKWEPLKIVLKKNRI
CCCCEEEECCCCCCCCEEEEEECCCC
>Mature Secondary Structure
MKSYLPSNTIFIVYICLFLFVSCAGFFRKKIPNSPLNDPRKMILVRIDPGRLGEFKEKTG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCHHHHCC
GKYNISYQESDSYYSVINKQDIDKFGFPSPGISVVKQYLPFKYYSGNYQELINERFTSLE
CEEEEEEECCCCHHHHHCCCCCHHCCCCCCCHHHHHHHCCCEECCCCHHHHHHHHHHHHH
DLKKGYKDNILNIHYLLGIANLYSEQSRMEVIGKTARGREIPALLLTNTTTPDEEKISVL
HHHCCHHCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHH
FNCAHHANEVISIEHCYDIIYSVLSRPKEYQEILNKMKIWIVPIVNPDGARHFWHVSNLM
HHHHHHCCCEEEHHHHHHHHHHHHCCCHHHHHHHHCCEEEEEEEECCCCCCHHHHHHHHH
GRKNGYPGSGPVNDKLNPGVDINRNYPFYWGKAGGGYSSSNPSNYFYRGPSPGSESETKA
HCCCCCCCCCCCCCCCCCCEECCCCCCEEECCCCCCCCCCCCCCEEEECCCCCCHHHHHH
MMDLANRERFAASISYHAYANCLLIPYSIDSLNNPEPDVAKEIGKKIAASVTSLNPEKEF
HHHHHHHHHHHHEEEHEEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHH
EAKKNIYPIDGVDQDYFYFAHGTLAYLLETTHLNPEYKEVEKVNVSLRKAWNLLLNEVLE
HHHCCCCCCCCCCCCEEEEECCHHEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
GKKIFLKITDEFGTPLEAKVEIERIKYFQEEIRVSNPINGFFFQLFPDRKETKVKISKEG
CCEEEEEEECCCCCCCCCEEHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEECCC
YEPTEIQTRPNGKWEPLKIVLKKNRI
CCCCEEEECCCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2118139 [H]