| Definition | Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_005823 |
| Length | 4,277,185 |
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The map label for this gene is hsdM [H]
Identifier: 45656820
GI number: 45656820
Start: 1123575
End: 1125116
Strand: Reverse
Name: hsdM [H]
Synonym: LIC10932
Alternate gene names: 45656820
Gene position: 1125116-1123575 (Counterclockwise)
Preceding gene: 45656821
Following gene: 45656819
Centisome position: 26.31
GC content: 43.97
Gene sequence:
>1542_bases ATGACAAGTGCTCAACAACGCGCTGCGCTACAACGCCAAATCTGGCAAATCGCAAATGATGTACGAGGTGCAGTCGACGG ATGGGATTTTAAACAGTATGTGCTGGGCACACTTTTTTACCGATTCATCAGCGAGAACTTTACCAACTACATGGAAGGTG GTGATAGTAGTATTCAGTATTCAAAACTAAACGATAAAAAAATCACCAAAGAGATCAAGGATGATGCCATTAAAACCAGG GGATATTTTATCTACCCAAGCCAGCTCTTCGCCAATATCGTTACCAAGGCTGACAAAAACGAGCGCTTAAATACAGACCT GGCTGGTATATTTAAAGACATCGAAAGTTCCGCCAACGGATTTCCATCAGAGCATGACATTAAAGGATTGTTTGCCGATT TTGATACTACGAGTAATCGCCTCGGGAACACAGTAAAAGATAAAAACAGCCGTCTTGCCGCCGTTCTCAAACGTGTGGCC GAGCTAGATTTTGGTGATTTTGATAGCAGTCATATCGATTTGTTTGGCGATGCCTACGAATTTCTCATCTCCAACTATGC GGCCAATGCAGGTAAATCCGGCGGTGAGTTTTTCACGCCCCAGCATGTCTCCAAGCTGATTGCTCGGCTGGCTATACACA AGCAGACACGCATCAATAAAATCTATGATCCCGCCTGTGGTTCCGGCTCCTTACTTTTACAAGCCAAAAAGCAATTTGAT GATCATATCATAGAAGAAGGTTTTTTCGGCCAGGAGATCAACCATACCACTTACAACCTCGCGCGAATGAATATGTTCTT GCATAATATCAACTACGATAAGTTCGATATCGAGCTGGGAAATACACTGATCGACCCTCAGCATAATCATGAAAAACCAT TTGATGCCATTGTCTCCAATCCTCCCTACTCGATTAACTGGAAAGGAAGCGATGATCCGACCTTGATCAACGACGAGCGT TTTGCGCCAGCAGGAGTATTGGCTCCTAAGTCCAAGGCAGACTTTGCCTTTGTGCTCCATGCACTCAGTTATTTATCGAG TAAGGGTCGTGCGGCCATTGTCTGCTTCCCCGGTATTTTTTACCGCAGTGGCGCCGAACAGAAAATCCGTCAGTATCTGG TAGGTAATAACTTTGTCGAAACCGTCATCTCACTTGCACCGAACTTGTTTTTTGGCACGACCATCGCCGTAAATATTCTG GTACTCTCTAAACATAAAACAGATACAAACACGCAGTTCATTGATGCAAGTGGTCTTTTCAAAAAAGAGACCAATAATAA TATACTCACCGAAGACCATATTGAACGGATCATGCAGACCTTCGATAGCAAGGTTGATACGGAGCACTTTGCAAAATCCG TAAGCGTTGAGACAATCGCCAACAACGATTACAATCTATCCGTAAGCAGTTATGTAGAAGCCAAGGACAACCGAGAAGTG ATCGATATCCAAAAACTCAACGCAGAGCTAAAAATCACCGTCGAAAAAATAGATCAGCTCCGTGCAGACATTGATGCAAT CGTTGCGGAGATTGAAGGGTGA
Upstream 100 bases:
>100_bases GATGAGCAGTCATTAGGCGATCACTGAGAATCCGTCAAGCAAACCTAAAGAACAATAAAACATATTACAATTTTAAACCT ACTTTCATAGGAAAATCATA
Downstream 100 bases:
>100_bases GCCAAAGGAGTTTTTTAGACCAGTTGTTGGATGGGGCGAAAGTGGAATGGAAGGCAGTTGAAGAAATTTTTGATCTAAGA AATGGATATACTCCTTCAAA
Product: type I restriction enzyme
Products: NA
Alternate protein names: M.EcoR124II [H]
Number of amino acids: Translated: 513; Mature: 512
Protein sequence:
>513_residues MTSAQQRAALQRQIWQIANDVRGAVDGWDFKQYVLGTLFYRFISENFTNYMEGGDSSIQYSKLNDKKITKEIKDDAIKTR GYFIYPSQLFANIVTKADKNERLNTDLAGIFKDIESSANGFPSEHDIKGLFADFDTTSNRLGNTVKDKNSRLAAVLKRVA ELDFGDFDSSHIDLFGDAYEFLISNYAANAGKSGGEFFTPQHVSKLIARLAIHKQTRINKIYDPACGSGSLLLQAKKQFD DHIIEEGFFGQEINHTTYNLARMNMFLHNINYDKFDIELGNTLIDPQHNHEKPFDAIVSNPPYSINWKGSDDPTLINDER FAPAGVLAPKSKADFAFVLHALSYLSSKGRAAIVCFPGIFYRSGAEQKIRQYLVGNNFVETVISLAPNLFFGTTIAVNIL VLSKHKTDTNTQFIDASGLFKKETNNNILTEDHIERIMQTFDSKVDTEHFAKSVSVETIANNDYNLSVSSYVEAKDNREV IDIQKLNAELKITVEKIDQLRADIDAIVAEIEG
Sequences:
>Translated_513_residues MTSAQQRAALQRQIWQIANDVRGAVDGWDFKQYVLGTLFYRFISENFTNYMEGGDSSIQYSKLNDKKITKEIKDDAIKTR GYFIYPSQLFANIVTKADKNERLNTDLAGIFKDIESSANGFPSEHDIKGLFADFDTTSNRLGNTVKDKNSRLAAVLKRVA ELDFGDFDSSHIDLFGDAYEFLISNYAANAGKSGGEFFTPQHVSKLIARLAIHKQTRINKIYDPACGSGSLLLQAKKQFD DHIIEEGFFGQEINHTTYNLARMNMFLHNINYDKFDIELGNTLIDPQHNHEKPFDAIVSNPPYSINWKGSDDPTLINDER FAPAGVLAPKSKADFAFVLHALSYLSSKGRAAIVCFPGIFYRSGAEQKIRQYLVGNNFVETVISLAPNLFFGTTIAVNIL VLSKHKTDTNTQFIDASGLFKKETNNNILTEDHIERIMQTFDSKVDTEHFAKSVSVETIANNDYNLSVSSYVEAKDNREV IDIQKLNAELKITVEKIDQLRADIDAIVAEIEG >Mature_512_residues TSAQQRAALQRQIWQIANDVRGAVDGWDFKQYVLGTLFYRFISENFTNYMEGGDSSIQYSKLNDKKITKEIKDDAIKTRG YFIYPSQLFANIVTKADKNERLNTDLAGIFKDIESSANGFPSEHDIKGLFADFDTTSNRLGNTVKDKNSRLAAVLKRVAE LDFGDFDSSHIDLFGDAYEFLISNYAANAGKSGGEFFTPQHVSKLIARLAIHKQTRINKIYDPACGSGSLLLQAKKQFDD HIIEEGFFGQEINHTTYNLARMNMFLHNINYDKFDIELGNTLIDPQHNHEKPFDAIVSNPPYSINWKGSDDPTLINDERF APAGVLAPKSKADFAFVLHALSYLSSKGRAAIVCFPGIFYRSGAEQKIRQYLVGNNFVETVISLAPNLFFGTTIAVNILV LSKHKTDTNTQFIDASGLFKKETNNNILTEDHIERIMQTFDSKVDTEHFAKSVSVETIANNDYNLSVSSYVEAKDNREVI DIQKLNAELKITVEKIDQLRADIDAIVAEIEG
Specific function: Methylation of specific adenine residues; required for both restriction and modification activities. The EcoR124/3 I enzyme recognizes 5'-GAAN(7)RTCG-3' [H]
COG id: COG0286
COG function: function code V; Type I restriction-modification system methyltransferase subunit
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]
Homologues:
Organism=Escherichia coli, GI1790808, Length=274, Percent_Identity=28.1021897810219, Blast_Score=90, Evalue=3e-19,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR022749 - InterPro: IPR003356 - InterPro: IPR002052 - InterPro: IPR002296 - InterPro: IPR004546 [H]
Pfam domain/function: PF12161 HsdM_N; PF02384 N6_Mtase [H]
EC number: =2.1.1.72 [H]
Molecular weight: Translated: 57664; Mature: 57533
Theoretical pI: Translated: 5.63; Mature: 5.63
Prosite motif: PS00092 N6_MTASE
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 1.0 %Met (Translated Protein) 1.4 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 0.8 %Met (Mature Protein) 1.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTSAQQRAALQRQIWQIANDVRGAVDGWDFKQYVLGTLFYRFISENFTNYMEGGDSSIQY CCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE SKLNDKKITKEIKDDAIKTRGYFIYPSQLFANIVTKADKNERLNTDLAGIFKDIESSANG ECCCHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCC FPSEHDIKGLFADFDTTSNRLGNTVKDKNSRLAAVLKRVAELDFGDFDSSHIDLFGDAYE CCCCCCCCHHEECCCCCHHHHCCCHHCCCHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHH FLISNYAANAGKSGGEFFTPQHVSKLIARLAIHKQTRINKIYDPACGSGSLLLQAKKQFD HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHH DHIIEEGFFGQEINHTTYNLARMNMFLHNINYDKFDIELGNTLIDPQHNHEKPFDAIVSN HHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCEEECCCCCCCCCHHHHHCC PPYSINWKGSDDPTLINDERFAPAGVLAPKSKADFAFVLHALSYLSSKGRAAIVCFPGIF CCEEEEECCCCCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCHH YRSGAEQKIRQYLVGNNFVETVISLAPNLFFGTTIAVNILVLSKHKTDTNTQFIDASGLF HHCCHHHHHHHHHHCCHHHHHHHHHCCCHHCCHHEEEEEEEEECCCCCCCCEEEECCCCE KKETNNNILTEDHIERIMQTFDSKVDTEHFAKSVSVETIANNDYNLSVSSYVEAKDNREV ECCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHCCEEEEECCCCEEEHHHHEECCCCCCE IDIQKLNAELKITVEKIDQLRADIDAIVAEIEG EEHEECCCEEEEEHHHHHHHHHHHHHHHHHCCC >Mature Secondary Structure TSAQQRAALQRQIWQIANDVRGAVDGWDFKQYVLGTLFYRFISENFTNYMEGGDSSIQY CCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE SKLNDKKITKEIKDDAIKTRGYFIYPSQLFANIVTKADKNERLNTDLAGIFKDIESSANG ECCCHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCC FPSEHDIKGLFADFDTTSNRLGNTVKDKNSRLAAVLKRVAELDFGDFDSSHIDLFGDAYE CCCCCCCCHHEECCCCCHHHHCCCHHCCCHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHH FLISNYAANAGKSGGEFFTPQHVSKLIARLAIHKQTRINKIYDPACGSGSLLLQAKKQFD HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHH DHIIEEGFFGQEINHTTYNLARMNMFLHNINYDKFDIELGNTLIDPQHNHEKPFDAIVSN HHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCEEECCCCCCCCCHHHHHCC PPYSINWKGSDDPTLINDERFAPAGVLAPKSKADFAFVLHALSYLSSKGRAAIVCFPGIF CCEEEEECCCCCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCHH YRSGAEQKIRQYLVGNNFVETVISLAPNLFFGTTIAVNILVLSKHKTDTNTQFIDASGLF HHCCHHHHHHHHHHCCHHHHHHHHHCCCHHCCHHEEEEEEEEECCCCCCCCEEEECCCCE KKETNNNILTEDHIERIMQTFDSKVDTEHFAKSVSVETIANNDYNLSVSSYVEAKDNREV ECCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHCCEEEEECCCCEEEHHHHEECCCCCCE IDIQKLNAELKITVEKIDQLRADIDAIVAEIEG EEHEECCCEEEEEHHHHHHHHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 2784505 [H]