| Definition | Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_005823 |
| Length | 4,277,185 |
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The map label for this gene is nprS [H]
Identifier: 45656613
GI number: 45656613
Start: 866582
End: 868984
Strand: Direct
Name: nprS [H]
Synonym: LIC10715
Alternate gene names: 45656613
Gene position: 866582-868984 (Clockwise)
Preceding gene: 45656608
Following gene: 45656618
Centisome position: 20.26
GC content: 39.87
Gene sequence:
>2403_bases ATGAAATATAAACAAAAGTTTGGATTTGAGAAAGTGAAAATATTTTTTCTTTATTTAGTGGTTTTTCTAAATTTTTTTCT ACAAGGTTGTAAAGATGGCGGTGGATCAACGTTCGGCGTAGAGTATTGGTTGGGAATGTTAAATTCGGTTCCGATGGATC CAAAGGCAGTCATGGAAAGTCAACTTTCTTCAAATGGTACTATAAACTTTGTCCGATTCAATTCAGACCTTGTTCCATAC AGTAGAAGTCAAGCTTCGGAGGTTTTGAAAACGTATCTACAAATTCCTACCGAATATACACCTAAACTTGTACGTTCAAA CGAATCTAACGGACAGGTTTTGGATCGTTTTCAACAATATTATAAAGGTATAAAGGTCGAAAATAAAATCTACACCGTAG TATCCAAAGATAATCGAATCGAGTTTATGGGAGGTGATTTTTCTGGGATCGAACAAGATTTAAACATAACTCCGAACTTA TCTAAAGAAGACGCCTTATCAAAGGCGTTAGTTCATTTTGGTGCAAAAAAATATCTTTGGGAATCGCCTGAAAGAGAAGA TAGACTTCGTTCCATTAAAGGAGATTCGAAGGCGACTTACTTTCCTAAAGGAGAATTGATCGTATACAATCGAGCTGAAT CAAATCTTAAAAATGAATATCGTCTAACGTATAAGTTCGGAATTTCTTCTTTAGAACCGCCGAGTTCAAAATACGTTTAT GTGGACGCTCGTTCTGGAGAGATTCTGGCGAGCAGAGATGCCAGACGCTTTGAAACTCAGCCTGGTGATGGCGGGGGAGG TACTACGCCACTGCCACCGCCCACGGATTTAGGAATTTGTTTTCCGGATCCAACACCTTGTATCAAAAATGCAACGGCTA AAACTCGATTTAGCGGATATAAGACAATCACAACCTGGACAGCAAGAGAAGAAAATCATTACGAGCTTAAGGATTATTCC AGAGGTAAAGGAATTATCACTTATTCTTGGGAGTTTGTAGATTTAGGCATTTTAGGCGTTCAACTTCAGAACATACCTAT GATCGATTCTGATAATTATTGGTCTGCGAGCGAATATCATGACGACTATAATCATGATGCGGTATTGGATGCGCATTGGG GCGCGGAAAAGACCTACGATTATTTTAAGACGGTTCACAATCATTCGGGATATGACAGAGACGGCGCCAAGGTAATCGGT AACGTTCATGCGTATGGCTTCGCTAATAATGCTCATTGGGATCCAATAACCGAGGAGATTTATTATTATTACTGTCCTCC GGAAAGTCTTTGTGCAACTGTTTATACAAGTCCTGGACAGATAGATCCTCAATATGATGATACTACTTCTCTTGATTTCG TATCTCATGAGTTTGGACATGGACTAAGCGCATATACTTCCGAATTAGGATATAGTCGTGGACCAGGAGCTTTGAACGAA GGTTTTTCGGATATTTGGAATATAGTCGTAAATCATTACGTAAATAAGATTCACGCAATGAATAAGAATATTTGGTTGTT TGGTGATGAGACTCGCCCATCGGGTGGTATACGCTCCGCTTCCAATCCAAAATCCACTACGGTTAAGTATCCGGGACCGA ATACATATAAAGGAGAATTGTGGGATTTTAGTGATGTAGACGTTCACAGGAACAGTAACGTTTTAAGCCATTGGTTCTAT ATACTCTCCAATGGAAAACAAGGAATCAATGATATTTGGTGTGAATACAATACTTCCGGTATCAGCATTGAGAAGGCGGA AAAAATAGCCTATTCATCATCATTGTATCTCTGGCCTACCGCTGAGTACCCTGATGTAAGATCAGCGAGTATCATGGCAT CCAAGTATTTATACGGATCGTTTTCGCAGGAAGTAAAAAGTACAATCGACGCTTGGGATGCGGTAGGAGTGCCGGCAAAT ACCAGTTCACGCGGTGGTGCAGGAATGAAGCCGGATTATTATATTACTTCGGTAAAACTTTCAGAGATGGAAAGAAATTC CGGGAACGATTGCGGATATAAAGACAGTACCTATCTAAATCAAACCATATATAAGGGTTTTACATATACGATTCGGTTGT CTAGTCGAGGAGATTCGATTATCAATATGCCGTCCAGAACACATAAATGGAGGGTATGGATCGATTTCGATCGGAACGGA ACGTTTAACAATTCTGTTAATTCGACTGAGCTAGTTGCTGAGGGAACGATTTCTTCTTATAACGGAGGAATAATTCAAAA AACTTTCACAATTCCTGCGGATGCTTTGACTGGGACTACTAGAATGCGCGTTTCGATGAAGGCGGCGACCGGTGCAGAGA CATATCCTCGTCCGGATGAAAAATTTATCCAAGGAGAAGTAGAAGACTATATGGTTACGATTCGCCCATTTATTGTTCTT TAA
Upstream 100 bases:
>100_bases ACAAGTGTTATAATTTAATAATTTTAAATATTCTAGAATTGTGTTGTAACTGGGTAAAAACGGAACCAACCCAATTCTGA AAATATAGGAGGAATATCAA
Downstream 100 bases:
>100_bases GAATAGGTTATTGTAGTCAGATGAGAAAGGCATTTTGGTAATCTAATTCCAATTAGAAGAAAGATCATTTCAATAGTTTT CGTAAAGGACCGATCGAATC
Product: thermolysin
Products: NA
Alternate protein names: Neutral protease [H]
Number of amino acids: Translated: 800; Mature: 800
Protein sequence:
>800_residues MKYKQKFGFEKVKIFFLYLVVFLNFFLQGCKDGGGSTFGVEYWLGMLNSVPMDPKAVMESQLSSNGTINFVRFNSDLVPY SRSQASEVLKTYLQIPTEYTPKLVRSNESNGQVLDRFQQYYKGIKVENKIYTVVSKDNRIEFMGGDFSGIEQDLNITPNL SKEDALSKALVHFGAKKYLWESPEREDRLRSIKGDSKATYFPKGELIVYNRAESNLKNEYRLTYKFGISSLEPPSSKYVY VDARSGEILASRDARRFETQPGDGGGGTTPLPPPTDLGICFPDPTPCIKNATAKTRFSGYKTITTWTAREENHYELKDYS RGKGIITYSWEFVDLGILGVQLQNIPMIDSDNYWSASEYHDDYNHDAVLDAHWGAEKTYDYFKTVHNHSGYDRDGAKVIG NVHAYGFANNAHWDPITEEIYYYYCPPESLCATVYTSPGQIDPQYDDTTSLDFVSHEFGHGLSAYTSELGYSRGPGALNE GFSDIWNIVVNHYVNKIHAMNKNIWLFGDETRPSGGIRSASNPKSTTVKYPGPNTYKGELWDFSDVDVHRNSNVLSHWFY ILSNGKQGINDIWCEYNTSGISIEKAEKIAYSSSLYLWPTAEYPDVRSASIMASKYLYGSFSQEVKSTIDAWDAVGVPAN TSSRGGAGMKPDYYITSVKLSEMERNSGNDCGYKDSTYLNQTIYKGFTYTIRLSSRGDSIINMPSRTHKWRVWIDFDRNG TFNNSVNSTELVAEGTISSYNGGIIQKTFTIPADALTGTTRMRVSMKAATGAETYPRPDEKFIQGEVEDYMVTIRPFIVL
Sequences:
>Translated_800_residues MKYKQKFGFEKVKIFFLYLVVFLNFFLQGCKDGGGSTFGVEYWLGMLNSVPMDPKAVMESQLSSNGTINFVRFNSDLVPY SRSQASEVLKTYLQIPTEYTPKLVRSNESNGQVLDRFQQYYKGIKVENKIYTVVSKDNRIEFMGGDFSGIEQDLNITPNL SKEDALSKALVHFGAKKYLWESPEREDRLRSIKGDSKATYFPKGELIVYNRAESNLKNEYRLTYKFGISSLEPPSSKYVY VDARSGEILASRDARRFETQPGDGGGGTTPLPPPTDLGICFPDPTPCIKNATAKTRFSGYKTITTWTAREENHYELKDYS RGKGIITYSWEFVDLGILGVQLQNIPMIDSDNYWSASEYHDDYNHDAVLDAHWGAEKTYDYFKTVHNHSGYDRDGAKVIG NVHAYGFANNAHWDPITEEIYYYYCPPESLCATVYTSPGQIDPQYDDTTSLDFVSHEFGHGLSAYTSELGYSRGPGALNE GFSDIWNIVVNHYVNKIHAMNKNIWLFGDETRPSGGIRSASNPKSTTVKYPGPNTYKGELWDFSDVDVHRNSNVLSHWFY ILSNGKQGINDIWCEYNTSGISIEKAEKIAYSSSLYLWPTAEYPDVRSASIMASKYLYGSFSQEVKSTIDAWDAVGVPAN TSSRGGAGMKPDYYITSVKLSEMERNSGNDCGYKDSTYLNQTIYKGFTYTIRLSSRGDSIINMPSRTHKWRVWIDFDRNG TFNNSVNSTELVAEGTISSYNGGIIQKTFTIPADALTGTTRMRVSMKAATGAETYPRPDEKFIQGEVEDYMVTIRPFIVL >Mature_800_residues MKYKQKFGFEKVKIFFLYLVVFLNFFLQGCKDGGGSTFGVEYWLGMLNSVPMDPKAVMESQLSSNGTINFVRFNSDLVPY SRSQASEVLKTYLQIPTEYTPKLVRSNESNGQVLDRFQQYYKGIKVENKIYTVVSKDNRIEFMGGDFSGIEQDLNITPNL SKEDALSKALVHFGAKKYLWESPEREDRLRSIKGDSKATYFPKGELIVYNRAESNLKNEYRLTYKFGISSLEPPSSKYVY VDARSGEILASRDARRFETQPGDGGGGTTPLPPPTDLGICFPDPTPCIKNATAKTRFSGYKTITTWTAREENHYELKDYS RGKGIITYSWEFVDLGILGVQLQNIPMIDSDNYWSASEYHDDYNHDAVLDAHWGAEKTYDYFKTVHNHSGYDRDGAKVIG NVHAYGFANNAHWDPITEEIYYYYCPPESLCATVYTSPGQIDPQYDDTTSLDFVSHEFGHGLSAYTSELGYSRGPGALNE GFSDIWNIVVNHYVNKIHAMNKNIWLFGDETRPSGGIRSASNPKSTTVKYPGPNTYKGELWDFSDVDVHRNSNVLSHWFY ILSNGKQGINDIWCEYNTSGISIEKAEKIAYSSSLYLWPTAEYPDVRSASIMASKYLYGSFSQEVKSTIDAWDAVGVPAN TSSRGGAGMKPDYYITSVKLSEMERNSGNDCGYKDSTYLNQTIYKGFTYTIRLSSRGDSIINMPSRTHKWRVWIDFDRNG TFNNSVNSTELVAEGTISSYNGGIIQKTFTIPADALTGTTRMRVSMKAATGAETYPRPDEKFIQGEVEDYMVTIRPFIVL
Specific function: Extracellular zinc metalloprotease [H]
COG id: COG3227
COG function: function code E; Zinc metalloprotease (elastase)
Gene ontology:
Cell location: Secreted [H]
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Belongs to the peptidase M4 family [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR005075 - InterPro: IPR013856 - InterPro: IPR001570 - InterPro: IPR011096 [H]
Pfam domain/function: PF07504 FTP; PF03413 PepSY; PF01447 Peptidase_M4; PF02868 Peptidase_M4_C [H]
EC number: =3.4.24.28 [H]
Molecular weight: Translated: 90334; Mature: 90334
Theoretical pI: Translated: 6.12; Mature: 6.12
Prosite motif: PS00013 PROKAR_LIPOPROTEIN
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.9 %Cys (Translated Protein) 1.8 %Met (Translated Protein) 2.6 %Cys+Met (Translated Protein) 0.9 %Cys (Mature Protein) 1.8 %Met (Mature Protein) 2.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKYKQKFGFEKVKIFFLYLVVFLNFFLQGCKDGGGSTFGVEYWLGMLNSVPMDPKAVMES CCCCHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHCCCCCHHHHHHH QLSSNGTINFVRFNSDLVPYSRSQASEVLKTYLQIPTEYTPKLVRSNESNGQVLDRFQQY HHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCHHHHHHHHH YKGIKVENKIYTVVSKDNRIEFMGGDFSGIEQDLNITPNLSKEDALSKALVHFGAKKYLW HCCCEECCEEEEEEECCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHC ESPEREDRLRSIKGDSKATYFPKGELIVYNRAESNLKNEYRLTYKFGISSLEPPSSKYVY CCCCHHHHHHHCCCCCCEEECCCCCEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCEEE VDARSGEILASRDARRFETQPGDGGGGTTPLPPPTDLGICFPDPTPCIKNATAKTRFSGY EECCCCCEEECCCCHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCHHHCCCCCHHCCCCC KTITTWTAREENHYELKDYSRGKGIITYSWEFVDLGILGVQLQNIPMIDSDNYWSASEYH EEEEEEECCCCCCEECCCCCCCCEEEEEEEEEEEEEEEEEEEECCCEECCCCCCCCHHCC DDYNHDAVLDAHWGAEKTYDYFKTVHNHSGYDRDGAKVIGNVHAYGFANNAHWDPITEEI CCCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCCCHHEEECEEEEEECCCCCCCCCCCCE YYYYCPPESLCATVYTSPGQIDPQYDDTTSLDFVSHEFGHGLSAYTSELGYSRGPGALNE EEEECCHHHHEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHCCCCCCCCCHHH GFSDIWNIVVNHYVNKIHAMNKNIWLFGDETRPSGGIRSASNPKSTTVKYPGPNTYKGEL HHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCEEECCCCCCCCCCC WDFSDVDVHRNSNVLSHWFYILSNGKQGINDIWCEYNTSGISIEKAEKIAYSSSLYLWPT CCCCCCCCCCCCCHHHEEEEEEECCCCCCCCEEEEECCCCCCHHHHHHHEECCEEEEEEC AEYPDVRSASIMASKYLYGSFSQEVKSTIDAWDAVGVPANTSSRGGAGMKPDYYITSVKL CCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEEE SEMERNSGNDCGYKDSTYLNQTIYKGFTYTIRLSSRGDSIINMPSRTHKWRVWIDFDRNG EHHHCCCCCCCCCCCCHHHHHHHHCCEEEEEEECCCCCCEEECCCCCEEEEEEEEECCCC TFNNSVNSTELVAEGTISSYNGGIIQKTFTIPADALTGTTRMRVSMKAATGAETYPRPDE CCCCCCCCCEEEEECCCCCCCCCEEEEEEECCCHHHCCCEEEEEEEEECCCCCCCCCCCH KFIQGEVEDYMVTIRPFIVL HHHHCCHHHEEEEEEEEEEC >Mature Secondary Structure MKYKQKFGFEKVKIFFLYLVVFLNFFLQGCKDGGGSTFGVEYWLGMLNSVPMDPKAVMES CCCCHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHCCCCCHHHHHHH QLSSNGTINFVRFNSDLVPYSRSQASEVLKTYLQIPTEYTPKLVRSNESNGQVLDRFQQY HHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCHHHHHHHHH YKGIKVENKIYTVVSKDNRIEFMGGDFSGIEQDLNITPNLSKEDALSKALVHFGAKKYLW HCCCEECCEEEEEEECCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHC ESPEREDRLRSIKGDSKATYFPKGELIVYNRAESNLKNEYRLTYKFGISSLEPPSSKYVY CCCCHHHHHHHCCCCCCEEECCCCCEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCEEE VDARSGEILASRDARRFETQPGDGGGGTTPLPPPTDLGICFPDPTPCIKNATAKTRFSGY EECCCCCEEECCCCHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCHHHCCCCCHHCCCCC KTITTWTAREENHYELKDYSRGKGIITYSWEFVDLGILGVQLQNIPMIDSDNYWSASEYH EEEEEEECCCCCCEECCCCCCCCEEEEEEEEEEEEEEEEEEEECCCEECCCCCCCCHHCC DDYNHDAVLDAHWGAEKTYDYFKTVHNHSGYDRDGAKVIGNVHAYGFANNAHWDPITEEI CCCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCCCHHEEECEEEEEECCCCCCCCCCCCE YYYYCPPESLCATVYTSPGQIDPQYDDTTSLDFVSHEFGHGLSAYTSELGYSRGPGALNE EEEECCHHHHEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHCCCCCCCCCHHH GFSDIWNIVVNHYVNKIHAMNKNIWLFGDETRPSGGIRSASNPKSTTVKYPGPNTYKGEL HHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCEEECCCCCCCCCCC WDFSDVDVHRNSNVLSHWFYILSNGKQGINDIWCEYNTSGISIEKAEKIAYSSSLYLWPT CCCCCCCCCCCCCHHHEEEEEEECCCCCCCCEEEEECCCCCCHHHHHHHEECCEEEEEEC AEYPDVRSASIMASKYLYGSFSQEVKSTIDAWDAVGVPANTSSRGGAGMKPDYYITSVKL CCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEEE SEMERNSGNDCGYKDSTYLNQTIYKGFTYTIRLSSRGDSIINMPSRTHKWRVWIDFDRNG EHHHCCCCCCCCCCCCHHHHHHHHCCEEEEEEECCCCCCEEECCCCCEEEEEEEEECCCC TFNNSVNSTELVAEGTISSYNGGIIQKTFTIPADALTGTTRMRVSMKAATGAETYPRPDE CCCCCCCCCEEEEECCCCCCCCCEEEEEEECCCHHHCCCEEEEEEEEECCCCCCCCCCCH KFIQGEVEDYMVTIRPFIVL HHHHCCHHHEEEEEEEEEEC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 2203733; 3149972 [H]