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The map label for this gene is ubiE [H]

Identifier: 45656550

GI number: 45656550

Start: 796409

End: 797101

Strand: Direct

Name: ubiE [H]

Synonym: LIC10652

Alternate gene names: 45656550

Gene position: 796409-797101 (Clockwise)

Preceding gene: 45656549

Following gene: 45656551

Centisome position: 18.62

GC content: 30.74

Gene sequence:

>693_bases
ATGATATTATTAAATAATATTAGAAATCAAAGGAGATTTTTTGACCTTTTTTCAGAAAGTTACGGTTTTATAGAATTTCT
CACGTTTGGCTTTGCCAATCGAATTAGAAAACGTTCTCTTACTATTTTGAATCCTTTAAGGAATGATATTATTTGTGATT
TGATGTGCGGGAGCGGTCAAAACATTGGAATTTTAAGAAAATATTTCCGTTATGAAAAAATCATAGGTTTGGACGTTTCT
AGTCGTATGATTGGACGTGCGCGAGATCGTTTTGGAAATGAGAATATTCTTTATATTACAGAAAACGTTTTGGCTTCTTC
TGTTCCTTCTAATTATTGTGATGCGGTTTGTTGTACTTTTGGATTAAAAAGCCTTTTACCTGAACAAAGGAATCTTTTAA
TTTCGGAAGTATATAGAATTTTAAAACCTTCTGGTACTTTCGTCTTTACAGAATTGTCCAAACCTGCGGGTTTTGTTTAT
ATTTTCTGGAAGTTTTATTTCGTATATTTCCTTCCTCTGATTGGAAAATTATTTTCTTATCCGTTTGTGAAAAATAAATA
TCTGGCAAATTCAATTTCTACTTTTAATAATATTCTTTCGGATGAACCATATTTTCGTTCTTTGTTTTCTAGAGTAAATT
TGTTTAGCTGGTATGGTGGAATTGTGACCGGTGTTTTCGGACAAAAATTTTAA

Upstream 100 bases:

>100_bases
ATTATATAGTTTTGAATAAACGCTTAAATCCTCTAAAATTAAGAGCCAAATTAAAATTGAAAAAAATGATCACATTAAAA
ATTAAATATATAAATAAAAT

Downstream 100 bases:

>100_bases
TGGTACTTCTCACGGATTCTAAAATATTTTTTTATACTTTCTTGATTAACTGAATATATAAAATATTCTAATTTCTTAAA
GTTATAAGAATTATAAATTT

Product: ubiquinone/menaquinone methyltransferase

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MILLNNIRNQRRFFDLFSESYGFIEFLTFGFANRIRKRSLTILNPLRNDIICDLMCGSGQNIGILRKYFRYEKIIGLDVS
SRMIGRARDRFGNENILYITENVLASSVPSNYCDAVCCTFGLKSLLPEQRNLLISEVYRILKPSGTFVFTELSKPAGFVY
IFWKFYFVYFLPLIGKLFSYPFVKNKYLANSISTFNNILSDEPYFRSLFSRVNLFSWYGGIVTGVFGQKF

Sequences:

>Translated_230_residues
MILLNNIRNQRRFFDLFSESYGFIEFLTFGFANRIRKRSLTILNPLRNDIICDLMCGSGQNIGILRKYFRYEKIIGLDVS
SRMIGRARDRFGNENILYITENVLASSVPSNYCDAVCCTFGLKSLLPEQRNLLISEVYRILKPSGTFVFTELSKPAGFVY
IFWKFYFVYFLPLIGKLFSYPFVKNKYLANSISTFNNILSDEPYFRSLFSRVNLFSWYGGIVTGVFGQKF
>Mature_230_residues
MILLNNIRNQRRFFDLFSESYGFIEFLTFGFANRIRKRSLTILNPLRNDIICDLMCGSGQNIGILRKYFRYEKIIGLDVS
SRMIGRARDRFGNENILYITENVLASSVPSNYCDAVCCTFGLKSLLPEQRNLLISEVYRILKPSGTFVFTELSKPAGFVY
IFWKFYFVYFLPLIGKLFSYPFVKNKYLANSISTFNNILSDEPYFRSLFSRVNLFSWYGGIVTGVFGQKF

Specific function: Methyltransferase required for the conversion of dimethylmenaquinone (DMKH2) to menaquinone (MKH2) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiE family [H]

Homologues:

Organism=Escherichia coli, GI48994983, Length=223, Percent_Identity=26.457399103139, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004033 [H]

Pfam domain/function: PF01209 Ubie_methyltran [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 26761; Mature: 26761

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILLNNIRNQRRFFDLFSESYGFIEFLTFGFANRIRKRSLTILNPLRNDIICDLMCGSGQ
CEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCC
NIGILRKYFRYEKIIGLDVSSRMIGRARDRFGNENILYITENVLASSVPSNYCDAVCCTF
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEHHHHHHCCCCHHHHHHHHHH
GLKSLLPEQRNLLISEVYRILKPSGTFVFTELSKPAGFVYIFWKFYFVYFLPLIGKLFSY
HHHHHCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCC
PFVKNKYLANSISTFNNILSDEPYFRSLFSRVNLFSWYGGIVTGVFGQKF
CCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MILLNNIRNQRRFFDLFSESYGFIEFLTFGFANRIRKRSLTILNPLRNDIICDLMCGSGQ
CEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCC
NIGILRKYFRYEKIIGLDVSSRMIGRARDRFGNENILYITENVLASSVPSNYCDAVCCTF
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEHHHHHHCCCCHHHHHHHHHH
GLKSLLPEQRNLLISEVYRILKPSGTFVFTELSKPAGFVYIFWKFYFVYFLPLIGKLFSY
HHHHHCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCC
PFVKNKYLANSISTFNNILSDEPYFRSLFSRVNLFSWYGGIVTGVFGQKF
CCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12566566 [H]