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The map label for this gene is ykuI [H]

Identifier: 45656539

GI number: 45656539

Start: 782652

End: 783980

Strand: Direct

Name: ykuI [H]

Synonym: LIC10641

Alternate gene names: 45656539

Gene position: 782652-783980 (Clockwise)

Preceding gene: 45656535

Following gene: 45656545

Centisome position: 18.3

GC content: 37.1

Gene sequence:

>1329_bases
TTGCGGAGCCCGGTTTCGCGGATTTCAGTAAAAGGATTTTTAAATAAGTACATGTTGTATAGCCAGGACACAAGCAATTT
ACTCTCTTATGGAGAAAACAATTATCAACCTCATTACCAGCCGATTCTGGAGGTAACTAATTGTAACATTATAGGATATG
AAGTTCTAGGAAGATTTTATTTTCCCGAAAAGAATGAATACCGTTCTTTGGGCTATCAGTTTCACAATCCTGAACTAGAT
GCAATTCGACTGATTCAAATCGATCGATTGATTCGAGAAAAAGCGATCCGACATCTCAAAGACTCCGGTTTACGAACAAA
ACTTTTCCTCAACATGATGCCTAATTTTCTATCTATGATTCATACAGGAGATGTATTGGATCTCAAAAGAATTCACGTTC
TCAATCTGATCGAAAAGTATGATATTCCGCCTTCTGAAGTGGTTTTAGAAATCACGGAAGATAAGTTTGACGGTAATATA
GAAAAACTTCTTTCGATTGTTAATGTGTTCAAAGACTACGGATTTAAAATTGCGGTGGATGATTTAGGAGTTGGGTTTTC
CAATTTGGAAAGAATCGGTTATATTCATCCTGATATAATGAAGGTGGACATCAAGATCATGCGGGAAAGTTTAAACCGAA
GATCTTTTAAGAACGTATTGAGTGCGATTGCAGACATGTCTCAAAAACTAGGTTCTGATCTTCTATTTGAAGGAATTGAA
ACGGAGGAAGAATTACATCTTGCTCTTTCTATGGGGGCGAATCTTCTCCAGGGATTTTATTTTTCAAGACCTCAAGTAGA
GTTTCAGGATAAAAAACAATTCAATAGAACTCTCAGAGATACTTTGGAAAAATTCTCTGGACTTCGGTTTATGGAACTTT
TAGAGGAATTTCAAAAAGGTCAGTCGGTTATAGATTCCTTGGGGGAAAAATTAGAAGCTCTTCGACATAATGGAAAAGAA
GATCTTCCTTTGGTTCTTCATCTGATGCTCTCGGAACTTCCCACGGAAATTCTTTCCGTATTTGCCTGTGATATTTTTGG
TTATCAGATTACTCCCACTTATTTTCGAGTTCATCCTGGCGAAGAGTGGGATTCCGATCTTACGGAAATTGGAAACAATT
ATGCCTGGAGACCTTTTTTCATCCGTCATAAAGCGAAGGTGGTTCAGAATGCTGCAAAATGGACTGTAACCGAACCAATG
TATGATATGGATCTTCACAAACAAGTTGTGATCTTTACTTATACTCTCAGAGATAATTATATTTTAGTAATTAAGATGGA
TTGGGAAAAGGAAGGCGGAGGATTGAAGACTGAGGATAGAAGACAATAA

Upstream 100 bases:

>100_bases
TACCTTTAAGATTGTCAGTTTTTTTAAGAGGTTTCAAAAAAAAAGAAGAATGTAGTCTTTCCTAATCCTGAATTAGGCGC
TTTTTTATCTGGAATTTTGC

Downstream 100 bases:

>100_bases
GCGGTAGAGTCGCTGGGTTTTCTTCGGAAAACGTAGTAGGGGAAATATTTCTCAGTATGTTTCATAGAATCTACTATTGA
ATTATAGATTCTAACTCTGA

Product: diguanylate phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MRSPVSRISVKGFLNKYMLYSQDTSNLLSYGENNYQPHYQPILEVTNCNIIGYEVLGRFYFPEKNEYRSLGYQFHNPELD
AIRLIQIDRLIREKAIRHLKDSGLRTKLFLNMMPNFLSMIHTGDVLDLKRIHVLNLIEKYDIPPSEVVLEITEDKFDGNI
EKLLSIVNVFKDYGFKIAVDDLGVGFSNLERIGYIHPDIMKVDIKIMRESLNRRSFKNVLSAIADMSQKLGSDLLFEGIE
TEEELHLALSMGANLLQGFYFSRPQVEFQDKKQFNRTLRDTLEKFSGLRFMELLEEFQKGQSVIDSLGEKLEALRHNGKE
DLPLVLHLMLSELPTEILSVFACDIFGYQITPTYFRVHPGEEWDSDLTEIGNNYAWRPFFIRHKAKVVQNAAKWTVTEPM
YDMDLHKQVVIFTYTLRDNYILVIKMDWEKEGGGLKTEDRRQ

Sequences:

>Translated_442_residues
MRSPVSRISVKGFLNKYMLYSQDTSNLLSYGENNYQPHYQPILEVTNCNIIGYEVLGRFYFPEKNEYRSLGYQFHNPELD
AIRLIQIDRLIREKAIRHLKDSGLRTKLFLNMMPNFLSMIHTGDVLDLKRIHVLNLIEKYDIPPSEVVLEITEDKFDGNI
EKLLSIVNVFKDYGFKIAVDDLGVGFSNLERIGYIHPDIMKVDIKIMRESLNRRSFKNVLSAIADMSQKLGSDLLFEGIE
TEEELHLALSMGANLLQGFYFSRPQVEFQDKKQFNRTLRDTLEKFSGLRFMELLEEFQKGQSVIDSLGEKLEALRHNGKE
DLPLVLHLMLSELPTEILSVFACDIFGYQITPTYFRVHPGEEWDSDLTEIGNNYAWRPFFIRHKAKVVQNAAKWTVTEPM
YDMDLHKQVVIFTYTLRDNYILVIKMDWEKEGGGLKTEDRRQ
>Mature_442_residues
MRSPVSRISVKGFLNKYMLYSQDTSNLLSYGENNYQPHYQPILEVTNCNIIGYEVLGRFYFPEKNEYRSLGYQFHNPELD
AIRLIQIDRLIREKAIRHLKDSGLRTKLFLNMMPNFLSMIHTGDVLDLKRIHVLNLIEKYDIPPSEVVLEITEDKFDGNI
EKLLSIVNVFKDYGFKIAVDDLGVGFSNLERIGYIHPDIMKVDIKIMRESLNRRSFKNVLSAIADMSQKLGSDLLFEGIE
TEEELHLALSMGANLLQGFYFSRPQVEFQDKKQFNRTLRDTLEKFSGLRFMELLEEFQKGQSVIDSLGEKLEALRHNGKE
DLPLVLHLMLSELPTEILSVFACDIFGYQITPTYFRVHPGEEWDSDLTEIGNNYAWRPFFIRHKAKVVQNAAKWTVTEPM
YDMDLHKQVVIFTYTLRDNYILVIKMDWEKEGGGLKTEDRRQ

Specific function: Unknown

COG id: COG2200

COG function: function code T; FOG: EAL domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI226510982, Length=253, Percent_Identity=25.6916996047431, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87082096, Length=133, Percent_Identity=30.0751879699248, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1790496, Length=244, Percent_Identity=26.2295081967213, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI87081921, Length=226, Percent_Identity=23.4513274336283, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI87081743, Length=243, Percent_Identity=23.8683127572016, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1787541, Length=247, Percent_Identity=23.4817813765182, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788849, Length=135, Percent_Identity=24.4444444444444, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87081845, Length=255, Percent_Identity=25.0980392156863, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788502, Length=228, Percent_Identity=25.4385964912281, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633
- InterPro:   IPR018842 [H]

Pfam domain/function: PF00563 EAL; PF10388 YkuI_C [H]

EC number: NA

Molecular weight: Translated: 51579; Mature: 51579

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSPVSRISVKGFLNKYMLYSQDTSNLLSYGENNYQPHYQPILEVTNCNIIGYEVLGRFY
CCCCHHHHHHHHHHHHHHEECCCHHHHHHCCCCCCCCCHHHHHEECCCCEEEHHHHHHHC
FPEKNEYRSLGYQFHNPELDAIRLIQIDRLIREKAIRHLKDSGLRTKLFLNMMPNFLSMI
CCCCCHHHHCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
HTGDVLDLKRIHVLNLIEKYDIPPSEVVLEITEDKFDGNIEKLLSIVNVFKDYGFKIAVD
HCCCCHHHHHHHHHHHHHHCCCCHHHEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEE
DLGVGFSNLERIGYIHPDIMKVDIKIMRESLNRRSFKNVLSAIADMSQKLGSDLLFEGIE
CCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCC
TEEELHLALSMGANLLQGFYFSRPQVEFQDKKQFNRTLRDTLEKFSGLRFMELLEEFQKG
CHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
QSVIDSLGEKLEALRHNGKEDLPLVLHLMLSELPTEILSVFACDIFGYQITPTYFRVHPG
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCEEEEECCC
EEWDSDLTEIGNNYAWRPFFIRHKAKVVQNAAKWTVTEPMYDMDLHKQVVIFTYTLRDNY
CCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHCEEECCCCCCCCCCCEEEEEEEEECCCE
ILVIKMDWEKEGGGLKTEDRRQ
EEEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MRSPVSRISVKGFLNKYMLYSQDTSNLLSYGENNYQPHYQPILEVTNCNIIGYEVLGRFY
CCCCHHHHHHHHHHHHHHEECCCHHHHHHCCCCCCCCCHHHHHEECCCCEEEHHHHHHHC
FPEKNEYRSLGYQFHNPELDAIRLIQIDRLIREKAIRHLKDSGLRTKLFLNMMPNFLSMI
CCCCCHHHHCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
HTGDVLDLKRIHVLNLIEKYDIPPSEVVLEITEDKFDGNIEKLLSIVNVFKDYGFKIAVD
HCCCCHHHHHHHHHHHHHHCCCCHHHEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEE
DLGVGFSNLERIGYIHPDIMKVDIKIMRESLNRRSFKNVLSAIADMSQKLGSDLLFEGIE
CCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCC
TEEELHLALSMGANLLQGFYFSRPQVEFQDKKQFNRTLRDTLEKFSGLRFMELLEEFQKG
CHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
QSVIDSLGEKLEALRHNGKEDLPLVLHLMLSELPTEILSVFACDIFGYQITPTYFRVHPG
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCEEEEECCC
EEWDSDLTEIGNNYAWRPFFIRHKAKVVQNAAKWTVTEPMYDMDLHKQVVIFTYTLRDNY
CCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHCEEECCCCCCCCCCCEEEEEEEEECCCE
ILVIKMDWEKEGGGLKTEDRRQ
EEEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]