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The map label for this gene is ybiT

Identifier: 45656436

GI number: 45656436

Start: 655378

End: 657012

Strand: Direct

Name: ybiT

Synonym: LIC10538

Alternate gene names: 45656436

Gene position: 655378-657012 (Clockwise)

Preceding gene: 45656434

Following gene: 45656437

Centisome position: 15.32

GC content: 40.37

Gene sequence:

>1635_bases
ATGATCAGCACTTCCGGATTGACTCTAAACTTTGGTAAAAAGATACTTTTTGAGAACGTTACCGTAAAGTTTAAGGAAAA
TTGCAGATACGGATTGATCGGAGCAAACGGTTCCGGAAAATCCACGTTTATGAAAATTCTCGCTGGGATAGAGCAAGCGG
CGAGTGGTTCTGTTTCTATAGACGCGGGTTTAAAATTAGGATATTTAAAACAAGATCACTACGAGTATGAAAATGAAACC
GTTTTGAATACAGTCATCATGGGAGACAAAGAACTTTGGGAAGTTTCTCAAGAAAGAGATGCGATCTATTCTAAACCGGA
GATGTCCGATGAAGATGGAATCAGAGTTTCCGAACTGGAAGAAAAATACGGAGAACTAGGCGGATACGAAGCGGAAAGCA
CCGCAGGGGAATTGTTAGAAGGATTAGGAATTCCTACCTCAAGTCATACTCAAACCCTTGCCTATTTAACGGGAGGATTT
AAACTGAGGGTTCTTTTGGCTCAGGTATTATTTCAAAAACCGGATATACTTCTTTTAGATGAACCTACCAACCACTTGGA
TATTAAGACCATTCATTGGTTAGAGGAATTTTTAACCAACTACCGCGGAGTGGTGATCGTAATTTCCCACGACCGTCACT
TTATCAATTCGATAGCGACTCATATTGCGGATTTAGATTATCAATCCTTAACAGTTTATCCGGGCAACTATGACGACTTT
ATGGAAGCTTCTACGATGGCCCGTGAACGTCTGTTAGACGAAAACAAACGTAAGAAAGAAAAGATCGCCGAACTACAAGA
TTTCGTAAATAGATTTAGTGCAAACGCGAGTAAGTCCAAACAAGCTACTTCTAGACAAAAGCAGATAGAAAAAATCAAGT
TAGACGATGTTAAACCTTCTTCTAGGGTTTCACCTTATATTCGTTTTAAAATGAAAAAGACACTTGGAAAGGACGTGATC
CTAGCAGAAAATATTTCCAAGTCTTACGATAGACCCATCTTCAAGGATTTTACGATCAACATTACTAAAGGTGAAAAGAT
CGCAATCATCGGAACCAACGGTGTTGGAAAAACGACTCTTTTAAAAACGTTAATGAAACAGATCGAACCAGATAATGGAA
AGGTGGCAATGGGAGATTCGGTCACTTCTTCTATTTTTCCACAGGATCATAGAGAAGGTATATTAGAAGATGCTGATACG
CTTGTAGACTGGCTTTACAGATACGCTGATCCAGGAACCGAGATGGAGGAAATCAGGGCGATATTAGGAAGAATGTTGTT
CAGCGGGGATATGGCCAAAAAACCGACTAGTGTACTTTCTGGAGGAGAAAAATCCAGGCTGATCATCGGAAGGATGATCA
TTTCCGGAGATAACCTTTTGGCCCTGGACGAACCTACGAACCATTTGGATTTGGAAACGATAGAAGCTTTGAATTATGCC
CTTTCCATATTTGAAGGAACCGTAATATTCGTTTCTCACGATCGAGAGTTCGTATCTTCACTTGCGACCCGTGTGATAGA
AGTTTCCACCGAAGGAATCCGTGATTTTAAAGGAACTTACGAAGACTTCCTAGAAAGAGAAGGCGCTGAATTTTACAAAC
GTTTATCTGGTGGTCCCGTTTTGGCAGAAACTTAA

Upstream 100 bases:

>100_bases
ACGTTTTCAACTTCGGTAGAATTTCAAAAGTACTTAATTCTACTTTTTATTGGCAAAAAACCCTATTTTGAAAATCATGG
TCATCAGGCAGGTATCCTAA

Downstream 100 bases:

>100_bases
GAGTTTGTCCCAAAAACTATCAAACAACCCGATTGAGTTTCACAAAATGGCGGGACTCATACAGAAATTATAATAACAAA
AGAATACTAAAAAACTATAA

Product: ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 544; Mature: 544

Protein sequence:

>544_residues
MISTSGLTLNFGKKILFENVTVKFKENCRYGLIGANGSGKSTFMKILAGIEQAASGSVSIDAGLKLGYLKQDHYEYENET
VLNTVIMGDKELWEVSQERDAIYSKPEMSDEDGIRVSELEEKYGELGGYEAESTAGELLEGLGIPTSSHTQTLAYLTGGF
KLRVLLAQVLFQKPDILLLDEPTNHLDIKTIHWLEEFLTNYRGVVIVISHDRHFINSIATHIADLDYQSLTVYPGNYDDF
MEASTMARERLLDENKRKKEKIAELQDFVNRFSANASKSKQATSRQKQIEKIKLDDVKPSSRVSPYIRFKMKKTLGKDVI
LAENISKSYDRPIFKDFTINITKGEKIAIIGTNGVGKTTLLKTLMKQIEPDNGKVAMGDSVTSSIFPQDHREGILEDADT
LVDWLYRYADPGTEMEEIRAILGRMLFSGDMAKKPTSVLSGGEKSRLIIGRMIISGDNLLALDEPTNHLDLETIEALNYA
LSIFEGTVIFVSHDREFVSSLATRVIEVSTEGIRDFKGTYEDFLEREGAEFYKRLSGGPVLAET

Sequences:

>Translated_544_residues
MISTSGLTLNFGKKILFENVTVKFKENCRYGLIGANGSGKSTFMKILAGIEQAASGSVSIDAGLKLGYLKQDHYEYENET
VLNTVIMGDKELWEVSQERDAIYSKPEMSDEDGIRVSELEEKYGELGGYEAESTAGELLEGLGIPTSSHTQTLAYLTGGF
KLRVLLAQVLFQKPDILLLDEPTNHLDIKTIHWLEEFLTNYRGVVIVISHDRHFINSIATHIADLDYQSLTVYPGNYDDF
MEASTMARERLLDENKRKKEKIAELQDFVNRFSANASKSKQATSRQKQIEKIKLDDVKPSSRVSPYIRFKMKKTLGKDVI
LAENISKSYDRPIFKDFTINITKGEKIAIIGTNGVGKTTLLKTLMKQIEPDNGKVAMGDSVTSSIFPQDHREGILEDADT
LVDWLYRYADPGTEMEEIRAILGRMLFSGDMAKKPTSVLSGGEKSRLIIGRMIISGDNLLALDEPTNHLDLETIEALNYA
LSIFEGTVIFVSHDREFVSSLATRVIEVSTEGIRDFKGTYEDFLEREGAEFYKRLSGGPVLAET
>Mature_544_residues
MISTSGLTLNFGKKILFENVTVKFKENCRYGLIGANGSGKSTFMKILAGIEQAASGSVSIDAGLKLGYLKQDHYEYENET
VLNTVIMGDKELWEVSQERDAIYSKPEMSDEDGIRVSELEEKYGELGGYEAESTAGELLEGLGIPTSSHTQTLAYLTGGF
KLRVLLAQVLFQKPDILLLDEPTNHLDIKTIHWLEEFLTNYRGVVIVISHDRHFINSIATHIADLDYQSLTVYPGNYDDF
MEASTMARERLLDENKRKKEKIAELQDFVNRFSANASKSKQATSRQKQIEKIKLDDVKPSSRVSPYIRFKMKKTLGKDVI
LAENISKSYDRPIFKDFTINITKGEKIAIIGTNGVGKTTLLKTLMKQIEPDNGKVAMGDSVTSSIFPQDHREGILEDADT
LVDWLYRYADPGTEMEEIRAILGRMLFSGDMAKKPTSVLSGGEKSRLIIGRMIISGDNLLALDEPTNHLDLETIEALNYA
LSIFEGTVIFVSHDREFVSSLATRVIEVSTEGIRDFKGTYEDFLEREGAEFYKRLSGGPVLAET

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=535, Percent_Identity=31.9626168224299, Blast_Score=275, Evalue=6e-74,
Organism=Homo sapiens, GI27881506, Length=521, Percent_Identity=30.3262955854127, Blast_Score=237, Evalue=2e-62,
Organism=Homo sapiens, GI10947137, Length=521, Percent_Identity=30.3262955854127, Blast_Score=237, Evalue=2e-62,
Organism=Homo sapiens, GI10947135, Length=524, Percent_Identity=28.6259541984733, Blast_Score=197, Evalue=2e-50,
Organism=Homo sapiens, GI69354671, Length=524, Percent_Identity=28.6259541984733, Blast_Score=197, Evalue=3e-50,
Organism=Homo sapiens, GI21536378, Length=232, Percent_Identity=27.5862068965517, Blast_Score=73, Evalue=8e-13,
Organism=Homo sapiens, GI31657092, Length=214, Percent_Identity=28.9719626168224, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI27881501, Length=244, Percent_Identity=27.4590163934426, Blast_Score=67, Evalue=5e-11,
Organism=Homo sapiens, GI30795238, Length=244, Percent_Identity=27.4590163934426, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI1787041, Length=531, Percent_Identity=55.9322033898305, Blast_Score=617, Evalue=1e-178,
Organism=Escherichia coli, GI1789751, Length=528, Percent_Identity=34.0909090909091, Blast_Score=305, Evalue=6e-84,
Organism=Escherichia coli, GI2367384, Length=544, Percent_Identity=31.9852941176471, Blast_Score=257, Evalue=2e-69,
Organism=Escherichia coli, GI1787182, Length=533, Percent_Identity=33.3958724202627, Blast_Score=248, Evalue=6e-67,
Organism=Escherichia coli, GI1788165, Length=223, Percent_Identity=26.9058295964126, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1787112, Length=222, Percent_Identity=30.1801801801802, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788761, Length=209, Percent_Identity=26.7942583732057, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1786253, Length=205, Percent_Identity=26.8292682926829, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI87082267, Length=236, Percent_Identity=23.3050847457627, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788225, Length=206, Percent_Identity=25.7281553398058, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1786803, Length=186, Percent_Identity=28.494623655914, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17553372, Length=550, Percent_Identity=33.0909090909091, Blast_Score=260, Evalue=1e-69,
Organism=Caenorhabditis elegans, GI17555318, Length=529, Percent_Identity=31.758034026465, Blast_Score=254, Evalue=1e-67,
Organism=Caenorhabditis elegans, GI17559834, Length=532, Percent_Identity=28.7593984962406, Blast_Score=229, Evalue=4e-60,
Organism=Saccharomyces cerevisiae, GI6321121, Length=553, Percent_Identity=32.0072332730561, Blast_Score=253, Evalue=5e-68,
Organism=Saccharomyces cerevisiae, GI6320874, Length=531, Percent_Identity=30.3201506591337, Blast_Score=239, Evalue=9e-64,
Organism=Saccharomyces cerevisiae, GI6325030, Length=422, Percent_Identity=25.3554502369668, Blast_Score=129, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6324314, Length=377, Percent_Identity=24.9336870026525, Blast_Score=110, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6323278, Length=378, Percent_Identity=25.9259259259259, Blast_Score=110, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6324985, Length=210, Percent_Identity=30.952380952381, Blast_Score=78, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6323217, Length=256, Percent_Identity=26.953125, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24666836, Length=534, Percent_Identity=32.2097378277154, Blast_Score=278, Evalue=6e-75,
Organism=Drosophila melanogaster, GI24642252, Length=534, Percent_Identity=29.2134831460674, Blast_Score=246, Evalue=3e-65,
Organism=Drosophila melanogaster, GI18859989, Length=534, Percent_Identity=29.2134831460674, Blast_Score=246, Evalue=3e-65,
Organism=Drosophila melanogaster, GI24641342, Length=539, Percent_Identity=28.5714285714286, Blast_Score=227, Evalue=2e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 60876; Mature: 60876

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISTSGLTLNFGKKILFENVTVKFKENCRYGLIGANGSGKSTFMKILAGIEQAASGSVSI
CCCCCCCEEECCCEEEECCCEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCEEE
DAGLKLGYLKQDHYEYENETVLNTVIMGDKELWEVSQERDAIYSKPEMSDEDGIRVSELE
ECCCEEEEEECCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
EKYGELGGYEAESTAGELLEGLGIPTSSHTQTLAYLTGGFKLRVLLAQVLFQKPDILLLD
HHHHHCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEHCCCHHHHHHHHHHHHCCCCEEEEE
EPTNHLDIKTIHWLEEFLTNYRGVVIVISHDRHFINSIATHIADLDYQSLTVYPGNYDDF
CCCCCCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCCHHH
MEASTMARERLLDENKRKKEKIAELQDFVNRFSANASKSKQATSRQKQIEKIKLDDVKPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCC
SRVSPYIRFKMKKTLGKDVILAENISKSYDRPIFKDFTINITKGEKIAIIGTNGVGKTTL
CCCCHHHEEEEHHHCCCCEEEEHHHHHHHCCCCEECEEEEEECCCEEEEEECCCCCHHHH
LKTLMKQIEPDNGKVAMGDSVTSSIFPQDHREGILEDADTLVDWLYRYADPGTEMEEIRA
HHHHHHHHCCCCCEEEECCCHHHHCCCCHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHH
ILGRMLFSGDMAKKPTSVLSGGEKSRLIIGRMIISGDNLLALDEPTNHLDLETIEALNYA
HHHHHHHCCCCCCCCHHHHCCCCCCEEEEEEEEECCCCEEEECCCCCCCCHHHHHHHHHH
LSIFEGTVIFVSHDREFVSSLATRVIEVSTEGIRDFKGTYEDFLEREGAEFYKRLSGGPV
HHHHCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCHHHHHHHHCCCCC
LAET
CCCC
>Mature Secondary Structure
MISTSGLTLNFGKKILFENVTVKFKENCRYGLIGANGSGKSTFMKILAGIEQAASGSVSI
CCCCCCCEEECCCEEEECCCEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCEEE
DAGLKLGYLKQDHYEYENETVLNTVIMGDKELWEVSQERDAIYSKPEMSDEDGIRVSELE
ECCCEEEEEECCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
EKYGELGGYEAESTAGELLEGLGIPTSSHTQTLAYLTGGFKLRVLLAQVLFQKPDILLLD
HHHHHCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEHCCCHHHHHHHHHHHHCCCCEEEEE
EPTNHLDIKTIHWLEEFLTNYRGVVIVISHDRHFINSIATHIADLDYQSLTVYPGNYDDF
CCCCCCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCCHHH
MEASTMARERLLDENKRKKEKIAELQDFVNRFSANASKSKQATSRQKQIEKIKLDDVKPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCC
SRVSPYIRFKMKKTLGKDVILAENISKSYDRPIFKDFTINITKGEKIAIIGTNGVGKTTL
CCCCHHHEEEEHHHCCCCEEEEHHHHHHHCCCCEECEEEEEECCCEEEEEECCCCCHHHH
LKTLMKQIEPDNGKVAMGDSVTSSIFPQDHREGILEDADTLVDWLYRYADPGTEMEEIRA
HHHHHHHHCCCCCEEEECCCHHHHCCCCHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHH
ILGRMLFSGDMAKKPTSVLSGGEKSRLIIGRMIISGDNLLALDEPTNHLDLETIEALNYA
HHHHHHHCCCCCCCCHHHHCCCCCCEEEEEEEEECCCCEEEECCCCCCCCHHHHHHHHHH
LSIFEGTVIFVSHDREFVSSLATRVIEVSTEGIRDFKGTYEDFLEREGAEFYKRLSGGPV
HHHHCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCHHHHHHHHCCCCC
LAET
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]