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The map label for this gene is etfA

Identifier: 45656263

GI number: 45656263

Start: 407883

End: 408842

Strand: Reverse

Name: etfA

Synonym: LIC10360

Alternate gene names: 45656263

Gene position: 408842-407883 (Counterclockwise)

Preceding gene: 45656264

Following gene: 45656262

Centisome position: 9.56

GC content: 42.6

Gene sequence:

>960_bases
GTGAGTAATGTATTCATTGTTGGAGAATTAAAAGACGGAGAACTGAAAAAAATCTCCAGAGAAATTACTTCTGCAGGTAG
AAAAATCGCAGATTCTATCGGTGGAAAAGTAATTGCACTTCTGATCGGAAATGGTGTCGAAAAACACGCTCCTGAATTGG
CTGCAGTTGGAGCCGATACAATCCTTACCGTAAATTCAGGCGATTACAACGCAGAAACATATTCTAATCAAGTTGCAGAA
GTAATCAAAGCACAAAACCCTGCAGTAGTTCTTCTTCCACATACTTCTCAAGGAAAAGATTATTCTCCTAGAGTAGCTGT
AAAGGTAGGGGCTGGAATTATCGCAGACGTTGTAGGATTTTCTGTAGATGGTGGAAAGGTTGTAGCAAAAAAACCAATCT
ATTCCGGAAAGGCTTACGCTAACTTCAAAGTAACAAGCCCGATTCAAATTTTTACCGTTCGTCCTAACTCTCAAGAGATT
ACTCAAAAAGCAGGTGCAGGCGCGGTAGAAGCAACTTCCCCTTCTGCAGGAAATGCAAAAGTAAAAATCGTATCTTCCGA
CTTAAGTGGCGGTTCTAAAGTTCAATTAACGGAAGCTTCTATCATTGTATCCGGTGGGCGCGGAATTAAAGGACCTGAAA
ACTGGCCTATCCTTCAAGAACTTGCTGACACACTGGGAGCAGCACTGGGAGCTTCTCGTGCAGCTGTGGATGCGGGATGG
ATTTCTCACTCTCATCAAGTAGGACAAACCGGAAAGACGGTTTCTCCAAATTGTTACATCGCTTGTGGAATTTCTGGCGC
AATCCAACACTTAGCTGGAATGGGATCCTCTAAGTATATCGTTGCAATCAACAAAGACGGAGATGCTCCTATTTTTAAAG
TAGCGACTTACGGTATCGTAGGAGACCTCTTCGAGGTAGTTCCTGCAGTAACTGCAGAGTTCAAAAAAGTACTTGGATAA

Upstream 100 bases:

>100_bases
TTCCAGGTAGAAAACTAGAAGCTGCAGATGCGAACGCATTTGCAGCTCAACTCGTGAAGGCTCTTAGAGAAGAAGCTAAG
GTTATATAAGGAGAACACAA

Downstream 100 bases:

>100_bases
TCCACCTGCAAAACGATCCGAAACTCATAAATGCCTTCCTATGGGGCGGCATTTAGGGAGTTGAGCATGAGTTTTTATTG
AAAAAAGTACTTGGATAATC

Product: electron transfer flavoprotein alpha-subunit

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MSNVFIVGELKDGELKKISREITSAGRKIADSIGGKVIALLIGNGVEKHAPELAAVGADTILTVNSGDYNAETYSNQVAE
VIKAQNPAVVLLPHTSQGKDYSPRVAVKVGAGIIADVVGFSVDGGKVVAKKPIYSGKAYANFKVTSPIQIFTVRPNSQEI
TQKAGAGAVEATSPSAGNAKVKIVSSDLSGGSKVQLTEASIIVSGGRGIKGPENWPILQELADTLGAALGASRAAVDAGW
ISHSHQVGQTGKTVSPNCYIACGISGAIQHLAGMGSSKYIVAINKDGDAPIFKVATYGIVGDLFEVVPAVTAEFKKVLG

Sequences:

>Translated_319_residues
MSNVFIVGELKDGELKKISREITSAGRKIADSIGGKVIALLIGNGVEKHAPELAAVGADTILTVNSGDYNAETYSNQVAE
VIKAQNPAVVLLPHTSQGKDYSPRVAVKVGAGIIADVVGFSVDGGKVVAKKPIYSGKAYANFKVTSPIQIFTVRPNSQEI
TQKAGAGAVEATSPSAGNAKVKIVSSDLSGGSKVQLTEASIIVSGGRGIKGPENWPILQELADTLGAALGASRAAVDAGW
ISHSHQVGQTGKTVSPNCYIACGISGAIQHLAGMGSSKYIVAINKDGDAPIFKVATYGIVGDLFEVVPAVTAEFKKVLG
>Mature_318_residues
SNVFIVGELKDGELKKISREITSAGRKIADSIGGKVIALLIGNGVEKHAPELAAVGADTILTVNSGDYNAETYSNQVAEV
IKAQNPAVVLLPHTSQGKDYSPRVAVKVGAGIIADVVGFSVDGGKVVAKKPIYSGKAYANFKVTSPIQIFTVRPNSQEIT
QKAGAGAVEATSPSAGNAKVKIVSSDLSGGSKVQLTEASIIVSGGRGIKGPENWPILQELADTLGAALGASRAAVDAGWI
SHSHQVGQTGKTVSPNCYIACGISGAIQHLAGMGSSKYIVAINKDGDAPIFKVATYGIVGDLFEVVPAVTAEFKKVLG

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=322, Percent_Identity=38.8198757763975, Blast_Score=193, Evalue=1e-49,
Organism=Homo sapiens, GI189181759, Length=220, Percent_Identity=47.2727272727273, Blast_Score=186, Evalue=2e-47,
Organism=Escherichia coli, GI1787990, Length=259, Percent_Identity=32.8185328185328, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1786226, Length=267, Percent_Identity=31.8352059925094, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI87082157, Length=237, Percent_Identity=31.2236286919831, Blast_Score=75, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17506929, Length=319, Percent_Identity=39.8119122257053, Blast_Score=191, Evalue=4e-49,
Organism=Saccharomyces cerevisiae, GI6325261, Length=317, Percent_Identity=32.4921135646688, Blast_Score=149, Evalue=6e-37,
Organism=Drosophila melanogaster, GI17136898, Length=318, Percent_Identity=39.622641509434, Blast_Score=191, Evalue=8e-49,
Organism=Drosophila melanogaster, GI24652801, Length=318, Percent_Identity=39.622641509434, Blast_Score=191, Evalue=8e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 32737; Mature: 32606

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNVFIVGELKDGELKKISREITSAGRKIADSIGGKVIALLIGNGVEKHAPELAAVGADT
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHCCCCEECCCCE
ILTVNSGDYNAETYSNQVAEVIKAQNPAVVLLPHTSQGKDYSPRVAVKVGAGIIADVVGF
EEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEEEECCCHHHHHHCC
SVDGGKVVAKKPIYSGKAYANFKVTSPIQIFTVRPNSQEITQKAGAGAVEATSPSAGNAK
CCCCCEEEEECCCCCCCEEEEEEECCCEEEEEECCCHHHHHHHCCCCCEECCCCCCCCEE
VKIVSSDLSGGSKVQLTEASIIVSGGRGIKGPENWPILQELADTLGAALGASRAAVDAGW
EEEEECCCCCCCEEEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHH
ISHSHQVGQTGKTVSPNCYIACGISGAIQHLAGMGSSKYIVAINKDGDAPIFKVATYGIV
HCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEHHHHH
GDLFEVVPAVTAEFKKVLG
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SNVFIVGELKDGELKKISREITSAGRKIADSIGGKVIALLIGNGVEKHAPELAAVGADT
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHCCCCEECCCCE
ILTVNSGDYNAETYSNQVAEVIKAQNPAVVLLPHTSQGKDYSPRVAVKVGAGIIADVVGF
EEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEEEECCCHHHHHHCC
SVDGGKVVAKKPIYSGKAYANFKVTSPIQIFTVRPNSQEITQKAGAGAVEATSPSAGNAK
CCCCCEEEEECCCCCCCEEEEEEECCCEEEEEECCCHHHHHHHCCCCCEECCCCCCCCEE
VKIVSSDLSGGSKVQLTEASIIVSGGRGIKGPENWPILQELADTLGAALGASRAAVDAGW
EEEEECCCCCCCEEEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHH
ISHSHQVGQTGKTVSPNCYIACGISGAIQHLAGMGSSKYIVAINKDGDAPIFKVATYGIV
HCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEHHHHH
GDLFEVVPAVTAEFKKVLG
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]