| Definition | Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_005823 |
| Length | 4,277,185 |
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The map label for this gene is pntB [H]
Identifier: 45656194
GI number: 45656194
Start: 331618
End: 333018
Strand: Direct
Name: pntB [H]
Synonym: LIC10290
Alternate gene names: 45656194
Gene position: 331618-333018 (Clockwise)
Preceding gene: 45656193
Following gene: 45656195
Centisome position: 7.75
GC content: 41.9
Gene sequence:
>1401_bases ATGACAGCATCAATTATTAATTTAATTTATCTCCTTTCCTCCATCCTTTTTATCATAGGATTAAAACTTCTTTCTCATCC AAAAACTGCGGTGCGTGGAAACTTCGTTGGAGCGGTTGGGATGTTTTTTGCCGTTGCTGCGGCGCTTGTAGAAAAAGGTC TTGCATACGAATATATCTTGGCCGGTTTCATTGTAGGAACTGCAATTGGAGTTTATCTTTCCGTAAAAGTGGAAATGACT TCTATGCCTCAGTTGGTTGCTGCGCTGAATGGTTTCGGAGGTCTTGCGTCCTTTTTAGTTGCCGGTGCGGCGATTATGGA AGTGCTTCATCAAGGAACTAATCTAGAAGTTCTTAAATCCTATCAATTTACAATTTCTACCGCTGCCTCTGGGATCATTG GTGCAGTTACTCTTACGGGCAGTTTTGTGGCTTATGGAAAACTACAAGGGATTCTTTCCGAAAAAGCGGTTCGTTATCCT GGAGATCAAATCGTAAAAGTGCTTTTCCTATTGGGTTCTTTAGTTCTAAGTTACTTCGTTGTTATTGAACCTCAAAAGAT AGAATGGTATTGGTATGTAGTTGTGGTAGGTTCTATACTCGGAATTTTACTGGTTATGCCGATCGGTGGAGCCGATATGC CCGTGGTAATCGCCCTTCTGAATTCTTATTCTGGAATTGCGGCATCTGCAACTGGGTTTGTTTTAGGTAATAACGTTCTT ATCATCGCCGGGTCTCTTGTAGGTGCCTCCGGAATTATACTAACACAGATTATGTGTAAGGCTATGAATCGTTCTTTGCC TAACGTTCTTTTTGGCGGGTTGGGGGCTGCTGTAGACAACTCCAAAGGTGGAGAGGATATCTACGCTGGAAAAACGAAAA GCACATCTGCAGAAGAAGTTGCTATGTTATTGGATATGGCCCAGAGGGTTGTGATTGTTCCAGGTTATGGAATGGCGGTT GCACAAGCTCAGCACGCTGTAAGAGATCTTTATAATATTCTAACAGACAGAGGAATCGACGTAGAATTTGCAATCCATCC AGTAGCGGGTAGAATGCCAGGTCACATGAACGTTTTACTTGCAGAAGCGGATATTCCTTATGATAAGATGAAGGAAATGG ATGAGATCAATCCTTCTTTCGAACAAGTGGACGTTGTGATCATCAACGGCGCTAATGATGTTGTCAATCCTCTTGCAAAA ACAGATCCAGGTAGTCCGATTGCTGGAATGCCGATTTTGGACGTAGACAAAGCAAAAACGGTTATCGTAATCAAAAGAAG TTTGAGTCCCGGTTTTGCGGGAGTTCCTAATCCTTTGTTTATCCAAGATAACGCTTTGATGTATTTTCAAGATGGTAAAA AAGCGACTCAAGAAATTGTTACTGCTCTCAAAGAAACCTAA
Upstream 100 bases:
>100_bases TTGGATTTATCGCGATGGTTGCGGCTACGATCAACGTAGTAGGTGGGTTCTTAGTAACTCATAGAATGTTAGGAATGTTC AAGAAGAAAGAAAAATAAAT
Downstream 100 bases:
>100_bases AAAGTTTTCTTTCTATAAATAACAGAATGTTTTAAGCCGGACTTTAAAAGTCCGGCTTTTTTGTTTGTGAAGAACGATTT TGAAATGGATTTCGTATTTT
Product: H+-translocating transhydrogenase subunit beta
Products: NA
Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit beta; Proton-translocating transhydrogenase NADP(H)-binding component; Pyridine nucleotide transhydrogenase subunit beta; dIII [H]
Number of amino acids: Translated: 466; Mature: 465
Protein sequence:
>466_residues MTASIINLIYLLSSILFIIGLKLLSHPKTAVRGNFVGAVGMFFAVAAALVEKGLAYEYILAGFIVGTAIGVYLSVKVEMT SMPQLVAALNGFGGLASFLVAGAAIMEVLHQGTNLEVLKSYQFTISTAASGIIGAVTLTGSFVAYGKLQGILSEKAVRYP GDQIVKVLFLLGSLVLSYFVVIEPQKIEWYWYVVVVGSILGILLVMPIGGADMPVVIALLNSYSGIAASATGFVLGNNVL IIAGSLVGASGIILTQIMCKAMNRSLPNVLFGGLGAAVDNSKGGEDIYAGKTKSTSAEEVAMLLDMAQRVVIVPGYGMAV AQAQHAVRDLYNILTDRGIDVEFAIHPVAGRMPGHMNVLLAEADIPYDKMKEMDEINPSFEQVDVVIINGANDVVNPLAK TDPGSPIAGMPILDVDKAKTVIVIKRSLSPGFAGVPNPLFIQDNALMYFQDGKKATQEIVTALKET
Sequences:
>Translated_466_residues MTASIINLIYLLSSILFIIGLKLLSHPKTAVRGNFVGAVGMFFAVAAALVEKGLAYEYILAGFIVGTAIGVYLSVKVEMT SMPQLVAALNGFGGLASFLVAGAAIMEVLHQGTNLEVLKSYQFTISTAASGIIGAVTLTGSFVAYGKLQGILSEKAVRYP GDQIVKVLFLLGSLVLSYFVVIEPQKIEWYWYVVVVGSILGILLVMPIGGADMPVVIALLNSYSGIAASATGFVLGNNVL IIAGSLVGASGIILTQIMCKAMNRSLPNVLFGGLGAAVDNSKGGEDIYAGKTKSTSAEEVAMLLDMAQRVVIVPGYGMAV AQAQHAVRDLYNILTDRGIDVEFAIHPVAGRMPGHMNVLLAEADIPYDKMKEMDEINPSFEQVDVVIINGANDVVNPLAK TDPGSPIAGMPILDVDKAKTVIVIKRSLSPGFAGVPNPLFIQDNALMYFQDGKKATQEIVTALKET >Mature_465_residues TASIINLIYLLSSILFIIGLKLLSHPKTAVRGNFVGAVGMFFAVAAALVEKGLAYEYILAGFIVGTAIGVYLSVKVEMTS MPQLVAALNGFGGLASFLVAGAAIMEVLHQGTNLEVLKSYQFTISTAASGIIGAVTLTGSFVAYGKLQGILSEKAVRYPG DQIVKVLFLLGSLVLSYFVVIEPQKIEWYWYVVVVGSILGILLVMPIGGADMPVVIALLNSYSGIAASATGFVLGNNVLI IAGSLVGASGIILTQIMCKAMNRSLPNVLFGGLGAAVDNSKGGEDIYAGKTKSTSAEEVAMLLDMAQRVVIVPGYGMAVA QAQHAVRDLYNILTDRGIDVEFAIHPVAGRMPGHMNVLLAEADIPYDKMKEMDEINPSFEQVDVVIINGANDVVNPLAKT DPGSPIAGMPILDVDKAKTVIVIKRSLSPGFAGVPNPLFIQDNALMYFQDGKKATQEIVTALKET
Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]
COG id: COG1282
COG function: function code C; NAD/NADP transhydrogenase beta subunit
Gene ontology:
Cell location: Cell inner membrane; Multi-pass membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the PNT beta subunit family [H]
Homologues:
Organism=Homo sapiens, GI122939155, Length=475, Percent_Identity=41.0526315789474, Blast_Score=318, Evalue=9e-87, Organism=Homo sapiens, GI122939153, Length=475, Percent_Identity=41.0526315789474, Blast_Score=318, Evalue=9e-87, Organism=Escherichia coli, GI1787886, Length=468, Percent_Identity=47.2222222222222, Blast_Score=379, Evalue=1e-106, Organism=Caenorhabditis elegans, GI17550456, Length=465, Percent_Identity=41.9354838709677, Blast_Score=314, Evalue=5e-86,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012136 - InterPro: IPR004003 [H]
Pfam domain/function: PF02233 PNTB [H]
EC number: =1.6.1.2 [H]
Molecular weight: Translated: 49191; Mature: 49059
Theoretical pI: Translated: 5.41; Mature: 5.41
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.2 %Cys (Translated Protein) 3.9 %Met (Translated Protein) 4.1 %Cys+Met (Translated Protein) 0.2 %Cys (Mature Protein) 3.7 %Met (Mature Protein) 3.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTASIINLIYLLSSILFIIGLKLLSHPKTAVRGNFVGAVGMFFAVAAALVEKGLAYEYIL CCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHH AGFIVGTAIGVYLSVKVEMTSMPQLVAALNGFGGLASFLVAGAAIMEVLHQGTNLEVLKS HHHHHHHHHHEEEEEEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEEHH YQFTISTAASGIIGAVTLTGSFVAYGKLQGILSEKAVRYPGDQIVKVLFLLGSLVLSYFV EEEEEEHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH VIEPQKIEWYWYVVVVGSILGILLVMPIGGADMPVVIALLNSYSGIAASATGFVLGNNVL EECCCEEEEEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEECCCCEEECCCEE IIAGSLVGASGIILTQIMCKAMNRSLPNVLFGGLGAAVDNSKGGEDIYAGKTKSTSAEEV EEEECHHCCCHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCEECCCCCCCCHHHH AMLLDMAQRVVIVPGYGMAVAQAQHAVRDLYNILTDRGIDVEFAIHPVAGRMPGHMNVLL HHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEEE AEADIPYDKMKEMDEINPSFEQVDVVIINGANDVVNPLAKTDPGSPIAGMPILDVDKAKT EECCCCHHHHHHHHHCCCCCHHEEEEEEECCCHHHHHHHCCCCCCCCCCCCEEECCCCCE VIVIKRSLSPGFAGVPNPLFIQDNALMYFQDGKKATQEIVTALKET EEEEEECCCCCCCCCCCCEEEECCEEEEEECCHHHHHHHHHHHHCC >Mature Secondary Structure TASIINLIYLLSSILFIIGLKLLSHPKTAVRGNFVGAVGMFFAVAAALVEKGLAYEYIL CHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHH AGFIVGTAIGVYLSVKVEMTSMPQLVAALNGFGGLASFLVAGAAIMEVLHQGTNLEVLKS HHHHHHHHHHEEEEEEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEEHH YQFTISTAASGIIGAVTLTGSFVAYGKLQGILSEKAVRYPGDQIVKVLFLLGSLVLSYFV EEEEEEHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH VIEPQKIEWYWYVVVVGSILGILLVMPIGGADMPVVIALLNSYSGIAASATGFVLGNNVL EECCCEEEEEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEECCCCEEECCCEE IIAGSLVGASGIILTQIMCKAMNRSLPNVLFGGLGAAVDNSKGGEDIYAGKTKSTSAEEV EEEECHHCCCHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCEECCCCCCCCHHHH AMLLDMAQRVVIVPGYGMAVAQAQHAVRDLYNILTDRGIDVEFAIHPVAGRMPGHMNVLL HHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEEE AEADIPYDKMKEMDEINPSFEQVDVVIINGANDVVNPLAKTDPGSPIAGMPILDVDKAKT EECCCCHHHHHHHHHCCCCCHHEEEEEEECCCHHHHHHHCCCCCCCCCCCCEEECCCCCE VIVIKRSLSPGFAGVPNPLFIQDNALMYFQDGKKATQEIVTALKET EEEEEECCCCCCCCCCCCEEEECCEEEEEECCHHHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 8075801 [H]