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The map label for this gene is queC

Identifier: 45656192

GI number: 45656192

Start: 330525

End: 331253

Strand: Direct

Name: queC

Synonym: LIC10288

Alternate gene names: 45656192

Gene position: 330525-331253 (Clockwise)

Preceding gene: 45656191

Following gene: 45656193

Centisome position: 7.73

GC content: 35.67

Gene sequence:

>729_bases
TTGAATTCTTCAAGTAACGAAAAAAATAAGGATCTAAATCGAAAAAATTTTTCCTCTAAAACTGATTCATCAAACAACAA
AGCAGTTGTACTTTTGTCTGGGGGATTGGATTCTACTACTTGTCTTTATCAAGCGATTGCGGACGGAAAAGAAATCCAAG
CTCTTTCCTTCGATTACGGCCAAAGACATAAAATCGAATTGTCTTACGCGAAAAAAGTAACACGTAAATTAGGAATTCCT
CACACGATTCAAAAGTTAAAACCGGAATTATTTTTAGGTTCGTCTCTTACACAAAAGTCGCTTCACGTTCCTAAAAATTC
TTTAAGAAAAGAAGAAATACCTAACACGTATGTTCCGGGGCGGAATATTCTTTTTCTTTCTTTTGCAGTTTCTCTTGCGG
AAGGAACCGGTTCTGATTCTATTTATATCGGAGTCAATTCGATGGATTATTCCGGTTATCCGGATTGTAGACCTGAATTC
ATCAAAATGTTTGAGATGGCAATTCAACTTGGAACTAAAAAAGGAAGTCAAGGTCCTTCGATTAAAATTTTAACTCCTCT
TCAAAATCTTTCTAAAAAAGAAATCGTTCTTCTTGGGAATCAATTGAAAGTTCCTTTTCATCTTACATTCTCTTGCTATG
ATCCTAAGAACGGGAAAGCATGTGGAAAATGCGACGCCTGTCTATTGAGAAAAAAAGGTTTTCAGGAGACTGGAGTTTCT
GAAAAGTGA

Upstream 100 bases:

>100_bases
ACTTTTGCCCTTACTTTATAAGATTACTTTGAATGAAACTTGTACCAGCGCTTGTATTTATGAAGGCCCTAATAAAAATT
CTAGTGTGTAGGGATGAATT

Downstream 100 bases:

>100_bases
TTTCATCGGTTGGCATTTGTTAACCTGACCTTCCTTAGCTCTCCAAAGGAAGGAATCTCTGCTTAGGAAAAGTTAGAATG
GAACAGTTCGTAGGTTACCT

Product: hypothetical protein

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MNSSSNEKNKDLNRKNFSSKTDSSNNKAVVLLSGGLDSTTCLYQAIADGKEIQALSFDYGQRHKIELSYAKKVTRKLGIP
HTIQKLKPELFLGSSLTQKSLHVPKNSLRKEEIPNTYVPGRNILFLSFAVSLAEGTGSDSIYIGVNSMDYSGYPDCRPEF
IKMFEMAIQLGTKKGSQGPSIKILTPLQNLSKKEIVLLGNQLKVPFHLTFSCYDPKNGKACGKCDACLLRKKGFQETGVS
EK

Sequences:

>Translated_242_residues
MNSSSNEKNKDLNRKNFSSKTDSSNNKAVVLLSGGLDSTTCLYQAIADGKEIQALSFDYGQRHKIELSYAKKVTRKLGIP
HTIQKLKPELFLGSSLTQKSLHVPKNSLRKEEIPNTYVPGRNILFLSFAVSLAEGTGSDSIYIGVNSMDYSGYPDCRPEF
IKMFEMAIQLGTKKGSQGPSIKILTPLQNLSKKEIVLLGNQLKVPFHLTFSCYDPKNGKACGKCDACLLRKKGFQETGVS
EK
>Mature_242_residues
MNSSSNEKNKDLNRKNFSSKTDSSNNKAVVLLSGGLDSTTCLYQAIADGKEIQALSFDYGQRHKIELSYAKKVTRKLGIP
HTIQKLKPELFLGSSLTQKSLHVPKNSLRKEEIPNTYVPGRNILFLSFAVSLAEGTGSDSIYIGVNSMDYSGYPDCRPEF
IKMFEMAIQLGTKKGSQGPSIKILTPLQNLSKKEIVLLGNQLKVPFHLTFSCYDPKNGKACGKCDACLLRKKGFQETGVS
EK

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=214, Percent_Identity=42.0560747663551, Blast_Score=161, Evalue=3e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_LEPIC (Q72VK9)

Other databases:

- EMBL:   AE016823
- RefSeq:   YP_000278.1
- ProteinModelPortal:   Q72VK9
- SMR:   Q72VK9
- GeneID:   2770610
- GenomeReviews:   AE016823_GR
- KEGG:   lic:LIC10288
- HOGENOM:   HBG553284
- OMA:   GWAEVLG
- ProtClustDB:   CLSK573455
- BioCyc:   LINT267671:LIC_10288-MONOMER
- HAMAP:   MF_01633_B
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 26720; Mature: 26720

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSSSNEKNKDLNRKNFSSKTDSSNNKAVVLLSGGLDSTTCLYQAIADGKEIQALSFDYG
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCC
QRHKIELSYAKKVTRKLGIPHTIQKLKPELFLGSSLTQKSLHVPKNSLRKEEIPNTYVPG
CCEEEEHHHHHHHHHHCCCCHHHHHCCCCEEECCCCCHHHHCCCHHHHHHHHCCCCCCCC
RNILFLSFAVSLAEGTGSDSIYIGVNSMDYSGYPDCRPEFIKMFEMAIQLGTKKGSQGPS
CCEEEEEEEHHHHCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
IKILTPLQNLSKKEIVLLGNQLKVPFHLTFSCYDPKNGKACGKCDACLLRKKGFQETGVS
EEEECCCCCCCCCEEEEECCEEEEEEEEEEEEECCCCCCCCCCHHHHHHHHCCCCCCCCC
EK
CC
>Mature Secondary Structure
MNSSSNEKNKDLNRKNFSSKTDSSNNKAVVLLSGGLDSTTCLYQAIADGKEIQALSFDYG
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCC
QRHKIELSYAKKVTRKLGIPHTIQKLKPELFLGSSLTQKSLHVPKNSLRKEEIPNTYVPG
CCEEEEHHHHHHHHHHCCCCHHHHHCCCCEEECCCCCHHHHCCCHHHHHHHHCCCCCCCC
RNILFLSFAVSLAEGTGSDSIYIGVNSMDYSGYPDCRPEFIKMFEMAIQLGTKKGSQGPS
CCEEEEEEEHHHHCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
IKILTPLQNLSKKEIVLLGNQLKVPFHLTFSCYDPKNGKACGKCDACLLRKKGFQETGVS
EEEECCCCCCCCCEEEEECCEEEEEEEEEEEEECCCCCCCCCCHHHHHHHHCCCCCCCCC
EK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA