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The map label for this gene is mtaD [H]

Identifier: 45656174

GI number: 45656174

Start: 306749

End: 307999

Strand: Reverse

Name: mtaD [H]

Synonym: LIC10270

Alternate gene names: 45656174

Gene position: 307999-306749 (Counterclockwise)

Preceding gene: 45656175

Following gene: 45656173

Centisome position: 7.2

GC content: 36.77

Gene sequence:

>1251_bases
ATGGAATACGAACTCGTAAATGCATGCATCGTAACTAAGGATAGATGGATTTCAAACGGAAGCATCGTAATTAAAGACGG
TATAATAGCTTCTGTAAACGCAGGCGGACCCCCTGCTGGAAAAAGAATTCGTTTAAATCTAAACGGATTGTATGTCTATC
CCGGACTGATCAATGGACACGATCATTTATTGAGTACTTATCTTCCAAGAGTAGCTCCAAGCAAACCTTATCTGAACTGG
CTTCCTTGGGACAACGATCTTAAATCTTCTATTGTATTTTCAGAAAGACAACAACTCGATCCGGAACAACTTTATCTTTT
AGGTTCTTATAAAAATCTAATTTCGGGGGTTACTTCCGTTCAAGATCATATTCCTCATTTTGTTCAAGATCCCTTTATCG
AAACGATGCCCGTAAGAATTTTAAACCGATTTACGCTGTCCCATAGTATCTGTACATATTCCTTAGATTGGGGAGACGGT
CCTGAAGAAGAATATGCAAAAGCTCTAAAACAAGATATTCCTTATATAACTTGTATTGCAGAAGGATTTGACTCCGAATC
TAGAGATTCTCTTAAAAACTTATATCAACTAGGATGTCTCGGAGAACATACCGTTTTAGTACACGGAATCGTATTATCAG
AATCAGATATTACTTTGATTGCTCAAAAAAAGTCTCATTTAGTCTGGTGTCCAGAAGCGAATTTATTTTTATACGAAAGA
ACAACGGATATTAAAGATGTATTAAAACACGGAGTTAACGTTTGCCTTGGAACGGATTCAAGTATCTGCGGTTCACTGAA
TCTTTTAGAAGAAATTAAGAATGCACGAAAATTCTATCAAACAGAATACGGAGAAGATCTTTCCCCGAAAACGCTTTTTG
AAATGGTTACGTCTAATCCTGCAAAAGCGTTTCGAATTGAAAAACAGCTAGGAAGTATCGAAGTGGGAAAAATTGCAGAC
CTAACAATCCTTACTCGAAATTTCGAAGATCCATACCTCAATCTTTGCGAGAGTAACCTAAACAGCATCCGTCTCGTTCT
ACGAGATGGACTTCCTGTCTATGGAGATATAAGTTTAAAATCTTTTTTTGAAGAATCCGGAGTAAGAGTGGAAAAAATTA
GTATAGAGAATGCTGAAAAATACTTAGTTGCATCCCCCGGAAAATTGCTCGAATCCCTTGTTGTTTCCCTTGGTTATAAA
AAGGATTTGGCTTTTTTTCCCGTACAAAAAGAATTTGATAACTTTGAGTAG

Upstream 100 bases:

>100_bases
TTCTTTAGAGTCCGGCAAAGGGCTCTATTTTCAACTCAACCATGGAAGTTCTGCGATCGATCCGAGTTTACAAATTCGTT
AAAAATTAAATATTAAAAAT

Downstream 100 bases:

>100_bases
GTAAATCCATTTGGCCGGTCCGATCATCAGAAATTATAAAGGCGGATCCATCATTTATTTTGAGAAGGACAAAGCTGAAG
ATATCTATGTCCTGAGAAAT

Product: chlorohydrolase family protein

Products: NA

Alternate protein names: MTA/SAH deaminase [H]

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MEYELVNACIVTKDRWISNGSIVIKDGIIASVNAGGPPAGKRIRLNLNGLYVYPGLINGHDHLLSTYLPRVAPSKPYLNW
LPWDNDLKSSIVFSERQQLDPEQLYLLGSYKNLISGVTSVQDHIPHFVQDPFIETMPVRILNRFTLSHSICTYSLDWGDG
PEEEYAKALKQDIPYITCIAEGFDSESRDSLKNLYQLGCLGEHTVLVHGIVLSESDITLIAQKKSHLVWCPEANLFLYER
TTDIKDVLKHGVNVCLGTDSSICGSLNLLEEIKNARKFYQTEYGEDLSPKTLFEMVTSNPAKAFRIEKQLGSIEVGKIAD
LTILTRNFEDPYLNLCESNLNSIRLVLRDGLPVYGDISLKSFFEESGVRVEKISIENAEKYLVASPGKLLESLVVSLGYK
KDLAFFPVQKEFDNFE

Sequences:

>Translated_416_residues
MEYELVNACIVTKDRWISNGSIVIKDGIIASVNAGGPPAGKRIRLNLNGLYVYPGLINGHDHLLSTYLPRVAPSKPYLNW
LPWDNDLKSSIVFSERQQLDPEQLYLLGSYKNLISGVTSVQDHIPHFVQDPFIETMPVRILNRFTLSHSICTYSLDWGDG
PEEEYAKALKQDIPYITCIAEGFDSESRDSLKNLYQLGCLGEHTVLVHGIVLSESDITLIAQKKSHLVWCPEANLFLYER
TTDIKDVLKHGVNVCLGTDSSICGSLNLLEEIKNARKFYQTEYGEDLSPKTLFEMVTSNPAKAFRIEKQLGSIEVGKIAD
LTILTRNFEDPYLNLCESNLNSIRLVLRDGLPVYGDISLKSFFEESGVRVEKISIENAEKYLVASPGKLLESLVVSLGYK
KDLAFFPVQKEFDNFE
>Mature_416_residues
MEYELVNACIVTKDRWISNGSIVIKDGIIASVNAGGPPAGKRIRLNLNGLYVYPGLINGHDHLLSTYLPRVAPSKPYLNW
LPWDNDLKSSIVFSERQQLDPEQLYLLGSYKNLISGVTSVQDHIPHFVQDPFIETMPVRILNRFTLSHSICTYSLDWGDG
PEEEYAKALKQDIPYITCIAEGFDSESRDSLKNLYQLGCLGEHTVLVHGIVLSESDITLIAQKKSHLVWCPEANLFLYER
TTDIKDVLKHGVNVCLGTDSSICGSLNLLEEIKNARKFYQTEYGEDLSPKTLFEMVTSNPAKAFRIEKQLGSIEVGKIAD
LTILTRNFEDPYLNLCESNLNSIRLVLRDGLPVYGDISLKSFFEESGVRVEKISIENAEKYLVASPGKLLESLVVSLGYK
KDLAFFPVQKEFDNFE

Specific function: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MTA/SAH deaminase family [H]

Homologues:

Organism=Escherichia coli, GI1789249, Length=130, Percent_Identity=28.4615384615385, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.28 [H]

Molecular weight: Translated: 46793; Mature: 46793

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYELVNACIVTKDRWISNGSIVIKDGIIASVNAGGPPAGKRIRLNLNGLYVYPGLINGH
CCCEEEEEEEEECCCEECCCCEEEECCEEEEECCCCCCCCCEEEEEECEEEEECCEECCH
DHLLSTYLPRVAPSKPYLNWLPWDNDLKSSIVFSERQQLDPEQLYLLGSYKNLISGVTSV
HHHHHHHHCCCCCCCCCCEECCCCCCHHHHHHHHHHHHCCHHHEEEEECHHHHHHHHHHH
QDHIPHFVQDPFIETMPVRILNRFTLSHSICTYSLDWGDGPEEEYAKALKQDIPYITCIA
HHHCCHHHCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEEE
EGFDSESRDSLKNLYQLGCLGEHTVLVHGIVLSESDITLIAQKKSHLVWCPEANLFLYER
CCCCCCHHHHHHHHHHHCCCCCCEEEEEEEEECCCCEEEEEECCCCEEECCCCCEEEEEC
TTDIKDVLKHGVNVCLGTDSSICGSLNLLEEIKNARKFYQTEYGEDLSPKTLFEMVTSNP
CCCHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCC
AKAFRIEKQLGSIEVGKIADLTILTRNFEDPYLNLCESNLNSIRLVLRDGLPVYGDISLK
HHHEEEHHHHCCEECCCEEEEEEEECCCCCHHHHHHHCCHHHEEEEECCCCCEEECCHHH
SFFEESGVRVEKISIENAEKYLVASPGKLLESLVVSLGYKKDLAFFPVQKEFDNFE
HHHHHCCCEEEEEECCCCCEEEEECCHHHHHHHHHHCCCCCCCEECCCHHHCCCCC
>Mature Secondary Structure
MEYELVNACIVTKDRWISNGSIVIKDGIIASVNAGGPPAGKRIRLNLNGLYVYPGLINGH
CCCEEEEEEEEECCCEECCCCEEEECCEEEEECCCCCCCCCEEEEEECEEEEECCEECCH
DHLLSTYLPRVAPSKPYLNWLPWDNDLKSSIVFSERQQLDPEQLYLLGSYKNLISGVTSV
HHHHHHHHCCCCCCCCCCEECCCCCCHHHHHHHHHHHHCCHHHEEEEECHHHHHHHHHHH
QDHIPHFVQDPFIETMPVRILNRFTLSHSICTYSLDWGDGPEEEYAKALKQDIPYITCIA
HHHCCHHHCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEEE
EGFDSESRDSLKNLYQLGCLGEHTVLVHGIVLSESDITLIAQKKSHLVWCPEANLFLYER
CCCCCCHHHHHHHHHHHCCCCCCEEEEEEEEECCCCEEEEEECCCCEEECCCCCEEEEEC
TTDIKDVLKHGVNVCLGTDSSICGSLNLLEEIKNARKFYQTEYGEDLSPKTLFEMVTSNP
CCCHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCC
AKAFRIEKQLGSIEVGKIADLTILTRNFEDPYLNLCESNLNSIRLVLRDGLPVYGDISLK
HHHEEEHHHHCCEECCCEEEEEEEECCCCCHHHHHHHCCHHHEEEEECCCCCEEECCHHH
SFFEESGVRVEKISIENAEKYLVASPGKLLESLVVSLGYKKDLAFFPVQKEFDNFE
HHHHHCCCEEEEEECCCCCEEEEECCHHHHHHHHHHCCCCCCCEECCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA