| Definition | Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_005823 |
| Length | 4,277,185 |
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The map label for this gene is lolD
Identifier: 45656138
GI number: 45656138
Start: 268725
End: 269402
Strand: Direct
Name: lolD
Synonym: LIC10233
Alternate gene names: 45656138
Gene position: 268725-269402 (Clockwise)
Preceding gene: 45656137
Following gene: 45656140
Centisome position: 6.28
GC content: 35.99
Gene sequence:
>678_bases GTGAGTCTGATCAAAGTAAGAAATTTAGTAAAAAATTATCATATTCTAGATAAAGAATTTAAGATTTTGGATCATTTAGA TCTGGACGTTGAAGAAGGCGAAATCGTTTCCGTAGAAGGGAAGTCTGGAATTGGAAAATCCACACTTTTAAATATTTTAG GTTCTATGGATTCTTCTGATTCAGGGGAAGTAAATGTCTGTGGAGTTTTATTAGATCAAATTTCTGAAATCGGGAAAGAA AAATTTAGAGCTGAAAAAGTTTCTTTTATTTTTCAACATCACCTTCTTCTTCCAGATTTTACCGCTTTAGAAAATGTAAG TATCCCTCTTTTGATCAATGGGATTCAGCCAGGTAAGGCTAGACAAATGTCGATCGAAATGTTGGATCGAGTTGGACTTA GAGAACGTCATGATAATTTTCCTTCTCAACTTTCCGGTGGAGAAAGCGCGAGGGTGGGAGTTGCAAGGGCGCTCGTGGCC GGAAAAAAGCTTGTACTTGCAGATGAACCTACTGGTAATTTAGATAGAGAAAATTCTCGTAATTTAATGGCTTTGATTTT AGAGCTACAAAAAGAATTCCGTTTTTCTATGGTCATAGTTACACACGATATGGAGTTGGCTTCTTTGGTTCATAAAAGAA ATCAACTTTCCGGTGGTAAACTTCAACCGATTTTATAA
Upstream 100 bases:
>100_bases GTTACTACTGCCGCTACGATTTTATCCGGAATTGCGGGTTATTTTCCTGCGAGATGGGCGGCTGGTCTCAATCCTGTGGA TACGATAAGGAACGACTAAC
Downstream 100 bases:
>100_bases TTAACTCATTTTAGATAATTTAACGGAACTCGGCGTAAGAAAACCTTAGAGAGTAAAACTCAATATTACTTTTCATGGAT TTCAGTATAGTGTTTCAATT
Product: ABC transporter ATP-binding protein
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 225; Mature: 224
Protein sequence:
>225_residues MSLIKVRNLVKNYHILDKEFKILDHLDLDVEEGEIVSVEGKSGIGKSTLLNILGSMDSSDSGEVNVCGVLLDQISEIGKE KFRAEKVSFIFQHHLLLPDFTALENVSIPLLINGIQPGKARQMSIEMLDRVGLRERHDNFPSQLSGGESARVGVARALVA GKKLVLADEPTGNLDRENSRNLMALILELQKEFRFSMVIVTHDMELASLVHKRNQLSGGKLQPIL
Sequences:
>Translated_225_residues MSLIKVRNLVKNYHILDKEFKILDHLDLDVEEGEIVSVEGKSGIGKSTLLNILGSMDSSDSGEVNVCGVLLDQISEIGKE KFRAEKVSFIFQHHLLLPDFTALENVSIPLLINGIQPGKARQMSIEMLDRVGLRERHDNFPSQLSGGESARVGVARALVA GKKLVLADEPTGNLDRENSRNLMALILELQKEFRFSMVIVTHDMELASLVHKRNQLSGGKLQPIL >Mature_224_residues SLIKVRNLVKNYHILDKEFKILDHLDLDVEEGEIVSVEGKSGIGKSTLLNILGSMDSSDSGEVNVCGVLLDQISEIGKEK FRAEKVSFIFQHHLLLPDFTALENVSIPLLINGIQPGKARQMSIEMLDRVGLRERHDNFPSQLSGGESARVGVARALVAG KKLVLADEPTGNLDRENSRNLMALILELQKEFRFSMVIVTHDMELASLVHKRNQLSGGKLQPIL
Specific function: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-de
COG id: COG1136
COG function: function code V; ABC-type antimicrobial peptide transport system, ATPase component
Gene ontology:
Cell location: Cell inner membrane; Peripheral membrane protein [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ABC transporter domain [H]
Homologues:
Organism=Homo sapiens, GI153792144, Length=222, Percent_Identity=28.8288288288288, Blast_Score=92, Evalue=3e-19, Organism=Homo sapiens, GI116734710, Length=221, Percent_Identity=28.9592760180996, Blast_Score=89, Evalue=4e-18, Organism=Homo sapiens, GI27262624, Length=221, Percent_Identity=30.7692307692308, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI27262626, Length=221, Percent_Identity=30.7692307692308, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI21536376, Length=220, Percent_Identity=30, Blast_Score=75, Evalue=4e-14, Organism=Homo sapiens, GI105990541, Length=208, Percent_Identity=28.3653846153846, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI27477115, Length=186, Percent_Identity=28.494623655914, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI45446740, Length=222, Percent_Identity=27.9279279279279, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI47078218, Length=222, Percent_Identity=27.9279279279279, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI27436953, Length=223, Percent_Identity=27.8026905829596, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI46592915, Length=174, Percent_Identity=34.4827586206897, Blast_Score=68, Evalue=5e-12, Organism=Homo sapiens, GI46592956, Length=174, Percent_Identity=34.4827586206897, Blast_Score=68, Evalue=5e-12, Organism=Homo sapiens, GI46592978, Length=174, Percent_Identity=34.4827586206897, Blast_Score=65, Evalue=3e-11, Organism=Homo sapiens, GI46592964, Length=174, Percent_Identity=34.4827586206897, Blast_Score=65, Evalue=3e-11, Organism=Homo sapiens, GI46592971, Length=174, Percent_Identity=34.4827586206897, Blast_Score=65, Evalue=3e-11, Organism=Homo sapiens, GI46592898, Length=174, Percent_Identity=34.4827586206897, Blast_Score=65, Evalue=4e-11, Organism=Homo sapiens, GI150417984, Length=200, Percent_Identity=28, Blast_Score=65, Evalue=6e-11, Organism=Homo sapiens, GI30795238, Length=223, Percent_Identity=22.8699551569507, Blast_Score=64, Evalue=8e-11, Organism=Homo sapiens, GI27881501, Length=223, Percent_Identity=22.8699551569507, Blast_Score=64, Evalue=8e-11, Organism=Homo sapiens, GI11967969, Length=214, Percent_Identity=29.4392523364486, Blast_Score=64, Evalue=1e-10, Organism=Escherichia coli, GI87081834, Length=219, Percent_Identity=43.37899543379, Blast_Score=182, Evalue=2e-47, Organism=Escherichia coli, GI1786703, Length=221, Percent_Identity=39.3665158371041, Blast_Score=164, Evalue=5e-42, Organism=Escherichia coli, GI1787105, Length=219, Percent_Identity=35.6164383561644, Blast_Score=151, Evalue=4e-38, Organism=Escherichia coli, GI1786398, Length=204, Percent_Identity=34.3137254901961, Blast_Score=128, Evalue=2e-31, Organism=Escherichia coli, GI1788225, Length=218, Percent_Identity=36.697247706422, Blast_Score=128, Evalue=3e-31, Organism=Escherichia coli, GI1787029, Length=212, Percent_Identity=35.8490566037736, Blast_Score=126, Evalue=1e-30, Organism=Escherichia coli, GI1789873, Length=188, Percent_Identity=37.2340425531915, Blast_Score=118, Evalue=4e-28, Organism=Escherichia coli, GI1788761, Length=214, Percent_Identity=32.2429906542056, Blast_Score=116, Evalue=1e-27, Organism=Escherichia coli, GI1789672, Length=214, Percent_Identity=32.7102803738318, Blast_Score=113, Evalue=9e-27, Organism=Escherichia coli, GI1786872, Length=215, Percent_Identity=34.8837209302326, Blast_Score=106, Evalue=1e-24, Organism=Escherichia coli, GI1786563, Length=185, Percent_Identity=35.1351351351351, Blast_Score=106, Evalue=1e-24, Organism=Escherichia coli, GI1787089, Length=191, Percent_Identity=33.5078534031414, Blast_Score=106, Evalue=1e-24, Organism=Escherichia coli, GI87081709, Length=209, Percent_Identity=29.6650717703349, Blast_Score=105, Evalue=3e-24, Organism=Escherichia coli, GI1789032, Length=186, Percent_Identity=32.258064516129, Blast_Score=104, Evalue=6e-24, Organism=Escherichia coli, GI145693107, Length=222, Percent_Identity=31.5315315315315, Blast_Score=103, Evalue=8e-24, Organism=Escherichia coli, GI87081791, Length=206, Percent_Identity=32.0388349514563, Blast_Score=103, Evalue=1e-23, Organism=Escherichia coli, GI1787712, Length=192, Percent_Identity=30.2083333333333, Blast_Score=102, Evalue=3e-23, Organism=Escherichia coli, GI1789963, Length=226, Percent_Identity=33.1858407079646, Blast_Score=100, Evalue=9e-23, Organism=Escherichia coli, GI1787164, Length=192, Percent_Identity=34.8958333333333, Blast_Score=100, Evalue=1e-22, Organism=Escherichia coli, GI1789962, Length=215, Percent_Identity=30.6976744186047, Blast_Score=98, Evalue=3e-22, Organism=Escherichia coli, GI1787370, Length=195, Percent_Identity=31.2820512820513, Blast_Score=94, Evalue=5e-21, Organism=Escherichia coli, GI1788506, Length=231, Percent_Identity=31.6017316017316, Blast_Score=94, Evalue=7e-21, Organism=Escherichia coli, GI1790544, Length=221, Percent_Identity=31.2217194570136, Blast_Score=94, Evalue=9e-21, Organism=Escherichia coli, GI1787547, Length=210, Percent_Identity=31.4285714285714, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI48994883, Length=212, Percent_Identity=30.6603773584906, Blast_Score=92, Evalue=3e-20, Organism=Escherichia coli, GI1786253, Length=220, Percent_Identity=30.9090909090909, Blast_Score=91, Evalue=4e-20, Organism=Escherichia coli, GI1790467, Length=227, Percent_Identity=30.3964757709251, Blast_Score=89, Evalue=2e-19, Organism=Escherichia coli, GI1788644, Length=203, Percent_Identity=32.512315270936, Blast_Score=89, Evalue=3e-19, Organism=Escherichia coli, GI1790534, Length=210, Percent_Identity=31.9047619047619, Blast_Score=88, Evalue=4e-19, Organism=Escherichia coli, GI48994997, Length=215, Percent_Identity=31.6279069767442, Blast_Score=88, Evalue=5e-19, Organism=Escherichia coli, GI1787500, Length=206, Percent_Identity=32.5242718446602, Blast_Score=87, Evalue=6e-19, Organism=Escherichia coli, GI87082267, Length=224, Percent_Identity=29.0178571428571, Blast_Score=86, Evalue=2e-18, Organism=Escherichia coli, GI1786698, Length=196, Percent_Identity=32.6530612244898, Blast_Score=84, Evalue=1e-17, Organism=Escherichia coli, GI1789891, Length=196, Percent_Identity=30.6122448979592, Blast_Score=83, Evalue=1e-17, Organism=Escherichia coli, GI1788450, Length=191, Percent_Identity=30.8900523560209, Blast_Score=83, Evalue=1e-17, Organism=Escherichia coli, GI1788053, Length=198, Percent_Identity=30.3030303030303, Blast_Score=82, Evalue=3e-17, Organism=Escherichia coli, GI1787548, Length=239, Percent_Identity=27.6150627615063, Blast_Score=82, Evalue=4e-17, Organism=Escherichia coli, GI1789586, Length=187, Percent_Identity=32.620320855615, Blast_Score=81, Evalue=7e-17, Organism=Escherichia coli, GI1787758, Length=185, Percent_Identity=27.5675675675676, Blast_Score=72, Evalue=2e-14, Organism=Escherichia coli, GI1789864, Length=211, Percent_Identity=26.5402843601896, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI1788165, Length=190, Percent_Identity=26.8421052631579, Blast_Score=68, Evalue=4e-13, Organism=Escherichia coli, GI48994943, Length=228, Percent_Identity=24.5614035087719, Blast_Score=67, Evalue=7e-13, Organism=Escherichia coli, GI1788210, Length=193, Percent_Identity=30.5699481865285, Blast_Score=67, Evalue=7e-13, Organism=Escherichia coli, GI1786345, Length=197, Percent_Identity=30.4568527918782, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI1790739, Length=197, Percent_Identity=31.4720812182741, Blast_Score=66, Evalue=2e-12, Organism=Escherichia coli, GI1786319, Length=195, Percent_Identity=27.6923076923077, Blast_Score=65, Evalue=2e-12, Organism=Escherichia coli, GI1787112, Length=196, Percent_Identity=30.6122448979592, Blast_Score=64, Evalue=8e-12, Organism=Escherichia coli, GI1790162, Length=218, Percent_Identity=28.4403669724771, Blast_Score=64, Evalue=9e-12, Organism=Escherichia coli, GI87081782, Length=191, Percent_Identity=26.7015706806283, Blast_Score=63, Evalue=1e-11, Organism=Escherichia coli, GI1787759, Length=217, Percent_Identity=24.4239631336406, Blast_Score=63, Evalue=1e-11, Organism=Escherichia coli, GI1786803, Length=199, Percent_Identity=24.1206030150754, Blast_Score=62, Evalue=3e-11, Organism=Escherichia coli, GI1787143, Length=211, Percent_Identity=26.5402843601896, Blast_Score=61, Evalue=5e-11, Organism=Escherichia coli, GI1789991, Length=210, Percent_Identity=27.1428571428571, Blast_Score=60, Evalue=9e-11, Organism=Caenorhabditis elegans, GI115533608, Length=194, Percent_Identity=28.8659793814433, Blast_Score=76, Evalue=1e-14, Organism=Caenorhabditis elegans, GI71983523, Length=224, Percent_Identity=26.3392857142857, Blast_Score=74, Evalue=8e-14, Organism=Caenorhabditis elegans, GI71983516, Length=224, Percent_Identity=26.3392857142857, Blast_Score=74, Evalue=8e-14, Organism=Caenorhabditis elegans, GI71983510, Length=224, Percent_Identity=26.3392857142857, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI193202349, Length=207, Percent_Identity=30.9178743961353, Blast_Score=71, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17541710, Length=193, Percent_Identity=30.0518134715026, Blast_Score=70, Evalue=7e-13, Organism=Caenorhabditis elegans, GI212646699, Length=187, Percent_Identity=28.3422459893048, Blast_Score=68, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17558664, Length=195, Percent_Identity=27.1794871794872, Blast_Score=67, Evalue=8e-12, Organism=Caenorhabditis elegans, GI17567269, Length=172, Percent_Identity=31.3953488372093, Blast_Score=65, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17510237, Length=229, Percent_Identity=24.8908296943231, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17565586, Length=224, Percent_Identity=28.125, Blast_Score=65, Evalue=4e-11, Organism=Caenorhabditis elegans, GI71996809, Length=186, Percent_Identity=27.9569892473118, Blast_Score=64, Evalue=8e-11, Organism=Saccharomyces cerevisiae, GI6319856, Length=194, Percent_Identity=28.8659793814433, Blast_Score=75, Evalue=1e-14, Organism=Drosophila melanogaster, GI116007328, Length=222, Percent_Identity=28.8288288288288, Blast_Score=94, Evalue=5e-20, Organism=Drosophila melanogaster, GI28574150, Length=222, Percent_Identity=28.8288288288288, Blast_Score=94, Evalue=6e-20, Organism=Drosophila melanogaster, GI24666092, Length=223, Percent_Identity=24.6636771300448, Blast_Score=77, Evalue=7e-15, Organism=Drosophila melanogaster, GI19920532, Length=194, Percent_Identity=29.8969072164948, Blast_Score=74, Evalue=7e-14, Organism=Drosophila melanogaster, GI24580930, Length=194, Percent_Identity=29.8969072164948, Blast_Score=74, Evalue=7e-14, Organism=Drosophila melanogaster, GI161076684, Length=214, Percent_Identity=29.9065420560748, Blast_Score=70, Evalue=8e-13, Organism=Drosophila melanogaster, GI24581617, Length=214, Percent_Identity=29.9065420560748, Blast_Score=70, Evalue=8e-13, Organism=Drosophila melanogaster, GI24581615, Length=214, Percent_Identity=29.9065420560748, Blast_Score=70, Evalue=8e-13, Organism=Drosophila melanogaster, GI161076682, Length=214, Percent_Identity=29.9065420560748, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24643674, Length=188, Percent_Identity=25.531914893617, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI24582014, Length=207, Percent_Identity=27.0531400966184, Blast_Score=67, Evalue=7e-12, Organism=Drosophila melanogaster, GI24582012, Length=207, Percent_Identity=27.0531400966184, Blast_Score=67, Evalue=7e-12, Organism=Drosophila melanogaster, GI24650853, Length=229, Percent_Identity=26.6375545851528, Blast_Score=67, Evalue=7e-12, Organism=Drosophila melanogaster, GI24650855, Length=229, Percent_Identity=26.6375545851528, Blast_Score=67, Evalue=7e-12, Organism=Drosophila melanogaster, GI85725262, Length=200, Percent_Identity=26.5, Blast_Score=67, Evalue=8e-12, Organism=Drosophila melanogaster, GI221512771, Length=221, Percent_Identity=27.1493212669683, Blast_Score=67, Evalue=9e-12, Organism=Drosophila melanogaster, GI116007184, Length=204, Percent_Identity=28.4313725490196, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI281362751, Length=231, Percent_Identity=26.4069264069264, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI221500365, Length=204, Percent_Identity=28.4313725490196, Blast_Score=67, Evalue=1e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR015854 - InterPro: IPR003593 - InterPro: IPR011924 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: NA
Molecular weight: Translated: 24946; Mature: 24815
Theoretical pI: Translated: 6.40; Mature: 6.40
Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 3.1 %Met (Translated Protein) 3.6 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 2.7 %Met (Mature Protein) 3.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSLIKVRNLVKNYHILDKEFKILDHLDLDVEEGEIVSVEGKSGIGKSTLLNILGSMDSSD CCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCC SGEVNVCGVLLDQISEIGKEKFRAEKVSFIFQHHLLLPDFTALENVSIPLLINGIQPGKA CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCEEEEECCCCCCH RQMSIEMLDRVGLRERHDNFPSQLSGGESARVGVARALVAGKKLVLADEPTGNLDRENSR HHHHHHHHHHCCCHHHHCCCCHHCCCCCCHHHHHHHHHHHCCEEEEECCCCCCCCCCCCC NLMALILELQKEFRFSMVIVTHDMELASLVHKRNQLSGGKLQPIL HHHHHHHHHHHHHCEEEEEEECCHHHHHHHHHHHCCCCCCCCCCC >Mature Secondary Structure SLIKVRNLVKNYHILDKEFKILDHLDLDVEEGEIVSVEGKSGIGKSTLLNILGSMDSSD CHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCC SGEVNVCGVLLDQISEIGKEKFRAEKVSFIFQHHLLLPDFTALENVSIPLLINGIQPGKA CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCEEEEECCCCCCH RQMSIEMLDRVGLRERHDNFPSQLSGGESARVGVARALVAGKKLVLADEPTGNLDRENSR HHHHHHHHHHCCCHHHHCCCCHHCCCCCCHHHHHHHHHHHCCEEEEECCCCCCCCCCCCC NLMALILELQKEFRFSMVIVTHDMELASLVHKRNQLSGGKLQPIL HHHHHHHHHHHHHCEEEEEEECCHHHHHHHHHHHCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 7.0
TargetDB status: NA
Availability: NA
References: NA