Click here to switch to the map view.

The map label for this gene is rmd

Identifier: 45656108

GI number: 45656108

Start: 231970

End: 232935

Strand: Direct

Name: rmd

Synonym: LIC10203

Alternate gene names: 45656108

Gene position: 231970-232935 (Clockwise)

Preceding gene: 45656103

Following gene: 45656111

Centisome position: 5.42

GC content: 36.96

Gene sequence:

>966_bases
ATGAAATGCCTAATAACGGGAGCGGGAGGTTTTGTTGGTAGTTATCTACTAAAAGAATTAAAACGATCTTATACCGATTT
TTTAGGAATAGGCATTCAATCCGGTCCTAATATAACAGAAGATCTTGAACTTCCGAAATCATATCGCTCCGTTGTTTGTG
ATATACGGAATTTAAACCAGGTTTGTTCTATCATCCATGAATTTTCACCGGATGTTATATTTCATCTTGCGGCACAACCT
TTTGTTCCAAAAGCGGTAGAAGATCCAGGCGAGACTTTGGAGATCAACATACATGGAACGTTGAATCTATTAGAATCTTT
GCGTTCTTTAAAAAAGAAAGTTCGTTTCGTTTATATTTCTTCTTCCGATGTTTATGGAAACGTTCCGGAATCTTATCTTC
CAGTTACAGAATCGGTCGTCCCTGCTCCTCTCAATCCGTATTCTTCTTCTAAATACTGTGCGGAAATTTATTGTCTACAA
TATCATAGATGGATTCAAGATCTTGAAATTGTAATTGCAAGACCTTTCAATCATACTGGTCCAAAGCAAGGTTTGAATTT
TGTGATTCCTAATTTTTGTTCTCAAGTTTTAAAAGCGCTTAAAAGACCCGAATCGGAAAGAAAAATTTTAGTAGGAGATC
TTTCGTCTTCGAGAGATTTTTTAGATGTAAGAGACGTTGTATGCGCGTATCGAATTCTTGCAGAAAGAGGGAAACCAGGT
GAAATTTATAATATTTGTTCTGGTAAGGAAGTGATCATCAGAGATGTGTTAGATGGAATCATTTCTACTTCAGGACAGAA
GATTCCGGTAGAAGTCGACTCTACTCGTTTTCGCCCTGCGGAAATGAGGCGCCTTTTTGGAGACAATCAGAAACTTAGGC
AACTTGGTTGGGAACCTCGTTTCGAATTATTGGATACAATTCAAGATATTTATAATAGCATTGAGCATAGTAGCTTAATA
TACTAG

Upstream 100 bases:

>100_bases
AAATTTATCTTCCATACTCAAAAGGGGGAAAGAATTTTATTCGATTGTTTTTTATTCATTTTCTAAAACAACAGTATTTT
TACGGAAAATCAAGAATTCT

Downstream 100 bases:

>100_bases
ATAACCTCAACAGAATGTTCTTAGACTCAGTATGTTGTTCTCCAACTTACATTAAATAACGTATGATGTAAGGAGCCATA
ACCAACCCCACAAGTATTTG

Product: oxidoreductase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MKCLITGAGGFVGSYLLKELKRSYTDFLGIGIQSGPNITEDLELPKSYRSVVCDIRNLNQVCSIIHEFSPDVIFHLAAQP
FVPKAVEDPGETLEINIHGTLNLLESLRSLKKKVRFVYISSSDVYGNVPESYLPVTESVVPAPLNPYSSSKYCAEIYCLQ
YHRWIQDLEIVIARPFNHTGPKQGLNFVIPNFCSQVLKALKRPESERKILVGDLSSSRDFLDVRDVVCAYRILAERGKPG
EIYNICSGKEVIIRDVLDGIISTSGQKIPVEVDSTRFRPAEMRRLFGDNQKLRQLGWEPRFELLDTIQDIYNSIEHSSLI
Y

Sequences:

>Translated_321_residues
MKCLITGAGGFVGSYLLKELKRSYTDFLGIGIQSGPNITEDLELPKSYRSVVCDIRNLNQVCSIIHEFSPDVIFHLAAQP
FVPKAVEDPGETLEINIHGTLNLLESLRSLKKKVRFVYISSSDVYGNVPESYLPVTESVVPAPLNPYSSSKYCAEIYCLQ
YHRWIQDLEIVIARPFNHTGPKQGLNFVIPNFCSQVLKALKRPESERKILVGDLSSSRDFLDVRDVVCAYRILAERGKPG
EIYNICSGKEVIIRDVLDGIISTSGQKIPVEVDSTRFRPAEMRRLFGDNQKLRQLGWEPRFELLDTIQDIYNSIEHSSLI
Y
>Mature_321_residues
MKCLITGAGGFVGSYLLKELKRSYTDFLGIGIQSGPNITEDLELPKSYRSVVCDIRNLNQVCSIIHEFSPDVIFHLAAQP
FVPKAVEDPGETLEINIHGTLNLLESLRSLKKKVRFVYISSSDVYGNVPESYLPVTESVVPAPLNPYSSSKYCAEIYCLQ
YHRWIQDLEIVIARPFNHTGPKQGLNFVIPNFCSQVLKALKRPESERKILVGDLSSSRDFLDVRDVVCAYRILAERGKPG
EIYNICSGKEVIIRDVLDGIISTSGQKIPVEVDSTRFRPAEMRRLFGDNQKLRQLGWEPRFELLDTIQDIYNSIEHSSLI
Y

Specific function: DTDP-L-RHAMNOSE BIOSYNTHESIS WITHIN THE O ANTIGEN BIOSYNTHESIS PATHWAY OF LIPOPOLYSACCHARIDE BIOSYNTHESIS. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI7657641, Length=320, Percent_Identity=28.75, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI4504031, Length=343, Percent_Identity=26.530612244898, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI56237023, Length=343, Percent_Identity=27.4052478134111, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI56118217, Length=343, Percent_Identity=27.4052478134111, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI189083684, Length=343, Percent_Identity=27.4052478134111, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1788353, Length=328, Percent_Identity=28.0487804878049, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1788366, Length=349, Percent_Identity=26.647564469914, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI48994969, Length=322, Percent_Identity=28.8819875776398, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1786974, Length=346, Percent_Identity=26.878612716763, Blast_Score=96, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17507723, Length=342, Percent_Identity=26.9005847953216, Blast_Score=100, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI133901786, Length=343, Percent_Identity=27.1137026239067, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17539422, Length=343, Percent_Identity=27.1137026239067, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI133901788, Length=343, Percent_Identity=27.1137026239067, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17539424, Length=343, Percent_Identity=27.1137026239067, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI133901790, Length=343, Percent_Identity=27.1137026239067, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17568069, Length=310, Percent_Identity=28.3870967741935, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI115532424, Length=319, Percent_Identity=26.3322884012539, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71982038, Length=350, Percent_Identity=29.4285714285714, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71982035, Length=348, Percent_Identity=29.5977011494253, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17539532, Length=324, Percent_Identity=26.5432098765432, Blast_Score=75, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6319493, Length=339, Percent_Identity=25.6637168141593, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24158427, Length=342, Percent_Identity=27.1929824561404, Blast_Score=102, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36290; Mature: 36290

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKCLITGAGGFVGSYLLKELKRSYTDFLGIGIQSGPNITEDLELPKSYRSVVCDIRNLNQ
CEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHH
VCSIIHEFSPDVIFHLAAQPFVPKAVEDPGETLEINIHGTLNLLESLRSLKKKVRFVYIS
HHHHHHHHCCHHEEHHHCCCCCCCHHCCCCCEEEEEECHHHHHHHHHHHHHHHEEEEEEE
SSDVYGNVPESYLPVTESVVPAPLNPYSSSKYCAEIYCLQYHRWIQDLEIVIARPFNHTG
CCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCC
PKQGLNFVIPNFCSQVLKALKRPESERKILVGDLSSSRDFLDVRDVVCAYRILAERGKPG
CCCCCCEECHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCC
EIYNICSGKEVIIRDVLDGIISTSGQKIPVEVDSTRFRPAEMRRLFGDNQKLRQLGWEPR
CEEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHCCCHHHHHCCCCCH
FELLDTIQDIYNSIEHSSLIY
HHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKCLITGAGGFVGSYLLKELKRSYTDFLGIGIQSGPNITEDLELPKSYRSVVCDIRNLNQ
CEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHH
VCSIIHEFSPDVIFHLAAQPFVPKAVEDPGETLEINIHGTLNLLESLRSLKKKVRFVYIS
HHHHHHHHCCHHEEHHHCCCCCCCHHCCCCCEEEEEECHHHHHHHHHHHHHHHEEEEEEE
SSDVYGNVPESYLPVTESVVPAPLNPYSSSKYCAEIYCLQYHRWIQDLEIVIARPFNHTG
CCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCC
PKQGLNFVIPNFCSQVLKALKRPESERKILVGDLSSSRDFLDVRDVVCAYRILAERGKPG
CCCCCCEECHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCC
EIYNICSGKEVIIRDVLDGIISTSGQKIPVEVDSTRFRPAEMRRLFGDNQKLRQLGWEPR
CEEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHCCCHHHHHCCCCCH
FELLDTIQDIYNSIEHSSLIY
HHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]