BacMap

Definition	Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chromosome chromosome I, complete sequence.
Accession	NC_005823
Length	4,277,185

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The map label for this gene is fabG [H]

Identifier: 45655933

GI number: 45655933

Start: 22359

End: 23102

Strand: Direct

Name: fabG [H]

Synonym: LIC10019

Alternate gene names: 45655933

Gene position: 22359-23102 (Clockwise)

Preceding gene: 45655932

Following gene: 45655934

Centisome position: 0.52

GC content: 38.71

Gene sequence:

>744_bases
TTGAACGATTTATTTAACGTAAAGAATAAAACGGTTTTAGTAACCGGTTCTACTCGAGGAATTGGAAGATATTTTGCAGA
AGGTTTTAAAAACGCAGGAGCCATTGTTTATGGAACCGGTTCTTCTCAAGAATCAATTAAGAAGTTTGACGGTTCCGGAA
TTAAAGGTTTTGCCGCGGATATTCGTCAACCGGATGTAATGACTCCAATTATTGAATCTATTGTCAAAGAACATGGAAGG
TTAGACGTCCTTGTAAATAACGCCGGAATTGCTTCTAATAAACCCGCGGCTTTTTTAAAAGAAGATGAAATTGAATCTAT
CATCCAAACGAATTTTACGGGAGTATTTAGAGCTTGTACTGCTTATTACAAGATTCATAAAAAGAAAGGCGGGAATATTA
TCAATATTGCATCTATTTTAGGAATGAGAGGAACAAAATTAGCTTCCGTTTATTCTGGGACCAAAGGTGCCGTGATCAAT
ATGACTCGTGCTCTTGCAGTCGAATGGATTGGTTCCGGTTATAGAGTGAATGCAATTTGTCCTGGCTTTATCGATACGGA
TATGACGGAGATGATTAAGGAAAAGCCTGATGTTTTAGAACAAATGACTAATGCGATTCCGATGGGAAGGCTTGGAAAAC
CAGAAGATTTAGTAGGGGCAGCGATTTTTTTTGCCAGCGACGCATCTTCTTATGTAACAGGACAAACGATTGTAGTAGAC
GGAGGAATCACCGCAGGACTTTAA

Upstream 100 bases:

>100_bases
GAACGAGGAAAAAAACCCTCTATCGCAAATGGATCGGAATCTATCGAAGATATTCGTCCTTGTTATCCAGTAAAACAACA
ATACAACCGGGAGTGATCCA

Downstream 100 bases:

>100_bases
ACAGTCTAACTTTTAATGATTCTTTCTCTTCATTCCATCAATCCTGAAAAAAGAAAGTTACAACAGATTTCGGATCAGTT
GTCTCAAGGTAAAATTTATA

Product: 3-oxoacyl-acyl carrier protein reductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MNDLFNVKNKTVLVTGSTRGIGRYFAEGFKNAGAIVYGTGSSQESIKKFDGSGIKGFAADIRQPDVMTPIIESIVKEHGR
LDVLVNNAGIASNKPAAFLKEDEIESIIQTNFTGVFRACTAYYKIHKKKGGNIINIASILGMRGTKLASVYSGTKGAVIN
MTRALAVEWIGSGYRVNAICPGFIDTDMTEMIKEKPDVLEQMTNAIPMGRLGKPEDLVGAAIFFASDASSYVTGQTIVVD
GGITAGL

Sequences:

>Translated_247_residues
MNDLFNVKNKTVLVTGSTRGIGRYFAEGFKNAGAIVYGTGSSQESIKKFDGSGIKGFAADIRQPDVMTPIIESIVKEHGR
LDVLVNNAGIASNKPAAFLKEDEIESIIQTNFTGVFRACTAYYKIHKKKGGNIINIASILGMRGTKLASVYSGTKGAVIN
MTRALAVEWIGSGYRVNAICPGFIDTDMTEMIKEKPDVLEQMTNAIPMGRLGKPEDLVGAAIFFASDASSYVTGQTIVVD
GGITAGL
>Mature_247_residues
MNDLFNVKNKTVLVTGSTRGIGRYFAEGFKNAGAIVYGTGSSQESIKKFDGSGIKGFAADIRQPDVMTPIIESIVKEHGR
LDVLVNNAGIASNKPAAFLKEDEIESIIQTNFTGVFRACTAYYKIHKKKGGNIINIASILGMRGTKLASVYSGTKGAVIN
MTRALAVEWIGSGYRVNAICPGFIDTDMTEMIKEKPDVLEQMTNAIPMGRLGKPEDLVGAAIFFASDASSYVTGQTIVVD
GGITAGL

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=239, Percent_Identity=33.4728033472803, Blast_Score=128, Evalue=5e-30,
Organism=Homo sapiens, GI15277342, Length=254, Percent_Identity=32.2834645669291, Blast_Score=122, Evalue=2e-28,
Organism=Homo sapiens, GI10190704, Length=246, Percent_Identity=31.7073170731707, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI32483357, Length=252, Percent_Identity=28.968253968254, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI19923817, Length=188, Percent_Identity=32.9787234042553, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI7705925, Length=247, Percent_Identity=29.5546558704453, Blast_Score=104, Evalue=6e-23,
Organism=Homo sapiens, GI59889578, Length=196, Percent_Identity=34.6938775510204, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI66933014, Length=222, Percent_Identity=29.7297297297297, Blast_Score=98, Evalue=6e-21,
Organism=Homo sapiens, GI31542939, Length=208, Percent_Identity=30.7692307692308, Blast_Score=92, Evalue=3e-19,
Organism=Homo sapiens, GI126723750, Length=254, Percent_Identity=27.1653543307087, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI5031737, Length=242, Percent_Identity=25.6198347107438, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI4503301, Length=205, Percent_Identity=28.780487804878, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI4504505, Length=219, Percent_Identity=26.4840182648402, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI4758504, Length=257, Percent_Identity=27.2373540856031, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI224922801, Length=186, Percent_Identity=27.4193548387097, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI310128830, Length=203, Percent_Identity=26.6009852216749, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI310115468, Length=203, Percent_Identity=26.6009852216749, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1787335, Length=245, Percent_Identity=37.1428571428571, Blast_Score=161, Evalue=5e-41,
Organism=Escherichia coli, GI1790717, Length=250, Percent_Identity=35.2, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1789208, Length=247, Percent_Identity=35.2226720647773, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI87082100, Length=248, Percent_Identity=37.5, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI87082160, Length=248, Percent_Identity=35.8870967741936, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI2367175, Length=243, Percent_Identity=34.156378600823, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1786812, Length=256, Percent_Identity=30.078125, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1788459, Length=243, Percent_Identity=31.2757201646091, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787905, Length=247, Percent_Identity=28.3400809716599, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI2367365, Length=239, Percent_Identity=30.1255230125523, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1789378, Length=249, Percent_Identity=27.710843373494, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789057, Length=257, Percent_Identity=27.6264591439689, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787820, Length=234, Percent_Identity=28.2051282051282, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1786701, Length=191, Percent_Identity=26.7015706806283, Blast_Score=61, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=243, Percent_Identity=35.3909465020576, Blast_Score=130, Evalue=9e-31,
Organism=Caenorhabditis elegans, GI17555706, Length=243, Percent_Identity=32.0987654320988, Blast_Score=120, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI17561402, Length=250, Percent_Identity=31.2, Blast_Score=107, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI193204405, Length=255, Percent_Identity=32.156862745098, Blast_Score=106, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI17562910, Length=261, Percent_Identity=29.8850574712644, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17562908, Length=257, Percent_Identity=31.9066147859922, Blast_Score=103, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17562904, Length=262, Percent_Identity=33.206106870229, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17562906, Length=257, Percent_Identity=31.5175097276265, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17563726, Length=257, Percent_Identity=30.3501945525292, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17562990, Length=262, Percent_Identity=30.5343511450382, Blast_Score=101, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI72000259, Length=259, Percent_Identity=32.4324324324324, Blast_Score=101, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17560150, Length=257, Percent_Identity=31.5175097276265, Blast_Score=101, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17560220, Length=255, Percent_Identity=30.5882352941176, Blast_Score=101, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17560332, Length=259, Percent_Identity=31.2741312741313, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI115534694, Length=249, Percent_Identity=28.1124497991968, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17551412, Length=258, Percent_Identity=30.6201550387597, Blast_Score=97, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17538480, Length=258, Percent_Identity=30.6201550387597, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17559104, Length=255, Percent_Identity=29.4117647058824, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17565030, Length=259, Percent_Identity=30.1158301158301, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17544670, Length=257, Percent_Identity=26.8482490272374, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17536651, Length=248, Percent_Identity=31.0483870967742, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17536025, Length=249, Percent_Identity=31.3253012048193, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17538182, Length=263, Percent_Identity=31.9391634980989, Blast_Score=90, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17531453, Length=256, Percent_Identity=32.03125, Blast_Score=90, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17538486, Length=260, Percent_Identity=27.6923076923077, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71994600, Length=244, Percent_Identity=27.4590163934426, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17560676, Length=247, Percent_Identity=24.6963562753036, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17561272, Length=209, Percent_Identity=29.1866028708134, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71994604, Length=243, Percent_Identity=26.7489711934156, Blast_Score=87, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17508651, Length=248, Percent_Identity=25, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=194, Percent_Identity=26.8041237113402, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI193203115, Length=204, Percent_Identity=25.9803921568627, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17564282, Length=205, Percent_Identity=27.3170731707317, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI193203117, Length=206, Percent_Identity=25.7281553398058, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI193207185, Length=124, Percent_Identity=33.8709677419355, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=256, Percent_Identity=28.90625, Blast_Score=81, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6323882, Length=194, Percent_Identity=31.4432989690722, Blast_Score=79, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6322861, Length=245, Percent_Identity=27.3469387755102, Blast_Score=77, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6320089, Length=190, Percent_Identity=27.8947368421053, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322067, Length=218, Percent_Identity=27.5229357798165, Blast_Score=66, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6322226, Length=193, Percent_Identity=27.979274611399, Blast_Score=65, Evalue=8e-12,
Organism=Drosophila melanogaster, GI23397609, Length=245, Percent_Identity=32.2448979591837, Blast_Score=116, Evalue=1e-26,
Organism=Drosophila melanogaster, GI21355319, Length=250, Percent_Identity=31.6, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI28571526, Length=246, Percent_Identity=30.4878048780488, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24639444, Length=243, Percent_Identity=31.2757201646091, Blast_Score=107, Evalue=8e-24,
Organism=Drosophila melanogaster, GI21357041, Length=246, Percent_Identity=30.0813008130081, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24644339, Length=252, Percent_Identity=29.7619047619048, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24644337, Length=256, Percent_Identity=31.640625, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24643142, Length=240, Percent_Identity=29.5833333333333, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI17737361, Length=255, Percent_Identity=29.0196078431373, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24581726, Length=203, Percent_Identity=28.0788177339901, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI281364892, Length=207, Percent_Identity=28.0193236714976, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24640492, Length=198, Percent_Identity=26.7676767676768, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24665264, Length=142, Percent_Identity=33.0985915492958, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24665247, Length=201, Percent_Identity=26.865671641791, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI221331216, Length=201, Percent_Identity=26.865671641791, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI221331218, Length=201, Percent_Identity=27.363184079602, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI18859837, Length=208, Percent_Identity=28.3653846153846, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24665243, Length=201, Percent_Identity=27.363184079602, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 26342; Mature: 26342

Theoretical pI: Translated: 8.99; Mature: 8.99

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDLFNVKNKTVLVTGSTRGIGRYFAEGFKNAGAIVYGTGSSQESIKKFDGSGIKGFAAD
CCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHCCCCCCHHHHH
IRQPDVMTPIIESIVKEHGRLDVLVNNAGIASNKPAAFLKEDEIESIIQTNFTGVFRACT
CCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHH
AYYKIHKKKGGNIINIASILGMRGTKLASVYSGTKGAVINMTRALAVEWIGSGYRVNAIC
HHHHHHHCCCCCEEEHHHHHCCCCCHHHHHHCCCCCCEEHHHHHHHHHHCCCCEEEEEEE
PGFIDTDMTEMIKEKPDVLEQMTNAIPMGRLGKPEDLVGAAIFFASDASSYVTGQTIVVD
CCCCCCCHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHHEEEEEECCCCCEECCCEEEEE
GGITAGL
CCCCCCC
>Mature Secondary Structure
MNDLFNVKNKTVLVTGSTRGIGRYFAEGFKNAGAIVYGTGSSQESIKKFDGSGIKGFAAD
CCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHCCCCCCHHHHH
IRQPDVMTPIIESIVKEHGRLDVLVNNAGIASNKPAAFLKEDEIESIIQTNFTGVFRACT
CCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHH
AYYKIHKKKGGNIINIASILGMRGTKLASVYSGTKGAVINMTRALAVEWIGSGYRVNAIC
HHHHHHHCCCCCEEEHHHHHCCCCCHHHHHHCCCCCCEEHHHHHHHHHHCCCCEEEEEEE
PGFIDTDMTEMIKEKPDVLEQMTNAIPMGRLGKPEDLVGAAIFFASDASSYVTGQTIVVD
CCCCCCCHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHHEEEEEECCCCCEECCCEEEEE
GGITAGL
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]