Click here to switch to the map view.

The map label for this gene is zraR [H]

Identifier: 45655927

GI number: 45655927

Start: 17484

End: 18377

Strand: Direct

Name: zraR [H]

Synonym: LIC10013

Alternate gene names: 45655927

Gene position: 17484-18377 (Clockwise)

Preceding gene: 45655926

Following gene: 45655929

Centisome position: 0.41

GC content: 32.44

Gene sequence:

>894_bases
TTGAATTCTGAAGAACATATTTTTATTGGCAACGCTTCGAATTCGATTAAGATATTCAATCGACTGAAATCTTTGTCCCA
GAGTAATCTGCCGTTATTTGTTACAGGAGGTCCAGGTAGCGGTAAAACTTTTGTTTCCAATTTAATTGCAAGTTTGTCTG
GTACAAATCCACAAATATTTATTATAGATTCTGATCATCACGAAAATCAGAGAAGTTTAGAATCGGCACTTTCGGTCAAA
GATAATGTATATTTTCTTTTTAAGGACTTTCCAAATTTTCCAAAAGAAAACCAAGCTTATCTATTAAAAAGAATCCGCGA
AAATCAAAACAATTCTCGTTTTGTTTTTATTTCTGGTAAAGAGTGGAAACAAAAATTAGAAGCCGGTCAGATTTTAGAAT
CTCTCTATTTTGAAATTTCTAATTTTAGATTAGACCTTCCGGATCTTAGAGAAAGAAAGGAAGATATTCCTCTTCTGATT
AAACATTTTTTAGAAATTCTTTCGGATAAATATAAACGAAAAGAAATTCGGCTGAGTGAGAAATTATATCATATTTTACT
AAATTATGATTTTCCTGGGAACATTAGACAACTGAGAAATTTGTTGGAAAGTATGATTTCCTTGTTTGCGGTTCGTATTT
TGGACGTAAAACATCTTCCACCTCAGATGTTCGAAACTTCGTACGTGTATTCTGAATTTATCGAAGTGAAAACCGGAATT
CCTTTGAGAGATTATGAAAGGGAGATTATCAAAAAGAATTTAATTCTTGTAAACGGAAATCGGGAAAAAGCCGCTAAAAT
ACTCGGGATTTCGGAAAGAACGATTTATAGAAAGATTATAGAATTCGGTCTTTCCGACGAAGTTGAAGGAAAAAATCTTC
CATCCGACGTTTAA

Upstream 100 bases:

>100_bases
AAATTACTTTCAGAATACAAATAAAAGTTCCTTTGAATGTATAATCCGAGGTAGAGTTTTACAGGTCAAAGGATTATAAT
CTTTACAAAGGACTCTTCAA

Downstream 100 bases:

>100_bases
AATAAAATAGAGATTCTTCTTTTTCCGAGTTGGTTTTGATTCGAATATTCATATCTATTAGAAAATCATAAAGTTCTCCA
ATTGTTTTATCCGAAAAAAA

Product: sigma 54 activator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MNSEEHIFIGNASNSIKIFNRLKSLSQSNLPLFVTGGPGSGKTFVSNLIASLSGTNPQIFIIDSDHHENQRSLESALSVK
DNVYFLFKDFPNFPKENQAYLLKRIRENQNNSRFVFISGKEWKQKLEAGQILESLYFEISNFRLDLPDLRERKEDIPLLI
KHFLEILSDKYKRKEIRLSEKLYHILLNYDFPGNIRQLRNLLESMISLFAVRILDVKHLPPQMFETSYVYSEFIEVKTGI
PLRDYEREIIKKNLILVNGNREKAAKILGISERTIYRKIIEFGLSDEVEGKNLPSDV

Sequences:

>Translated_297_residues
MNSEEHIFIGNASNSIKIFNRLKSLSQSNLPLFVTGGPGSGKTFVSNLIASLSGTNPQIFIIDSDHHENQRSLESALSVK
DNVYFLFKDFPNFPKENQAYLLKRIRENQNNSRFVFISGKEWKQKLEAGQILESLYFEISNFRLDLPDLRERKEDIPLLI
KHFLEILSDKYKRKEIRLSEKLYHILLNYDFPGNIRQLRNLLESMISLFAVRILDVKHLPPQMFETSYVYSEFIEVKTGI
PLRDYEREIIKKNLILVNGNREKAAKILGISERTIYRKIIEFGLSDEVEGKNLPSDV
>Mature_297_residues
MNSEEHIFIGNASNSIKIFNRLKSLSQSNLPLFVTGGPGSGKTFVSNLIASLSGTNPQIFIIDSDHHENQRSLESALSVK
DNVYFLFKDFPNFPKENQAYLLKRIRENQNNSRFVFISGKEWKQKLEAGQILESLYFEISNFRLDLPDLRERKEDIPLLI
KHFLEILSDKYKRKEIRLSEKLYHILLNYDFPGNIRQLRNLLESMISLFAVRILDVKHLPPQMFETSYVYSEFIEVKTGI
PLRDYEREIIKKNLILVNGNREKAAKILGISERTIYRKIIEFGLSDEVEGKNLPSDV

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG3829

COG function: function code KT; Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=302, Percent_Identity=22.5165562913907, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1790299, Length=342, Percent_Identity=23.0994152046784, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788550, Length=327, Percent_Identity=24.4648318042813, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1789233, Length=329, Percent_Identity=25.531914893617, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788905, Length=292, Percent_Identity=21.5753424657534, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789087, Length=238, Percent_Identity=23.9495798319328, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI87082117, Length=310, Percent_Identity=22.5806451612903, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786524, Length=174, Percent_Identity=30.4597701149425, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1787583, Length=294, Percent_Identity=23.1292517006803, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 34515; Mature: 34515

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSEEHIFIGNASNSIKIFNRLKSLSQSNLPLFVTGGPGSGKTFVSNLIASLSGTNPQIF
CCCCCEEEEECCCCHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCEEE
IIDSDHHENQRSLESALSVKDNVYFLFKDFPNFPKENQAYLLKRIRENQNNSRFVFISGK
EEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCCEEEEEECH
EWKQKLEAGQILESLYFEISNFRLDLPDLRERKEDIPLLIKHFLEILSDKYKRKEIRLSE
HHHHHHHHHHHHHHHHHHHHCCEECCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
KLYHILLNYDFPGNIRQLRNLLESMISLFAVRILDVKHLPPQMFETSYVYSEFIEVKTGI
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCC
PLRDYEREIIKKNLILVNGNREKAAKILGISERTIYRKIIEFGLSDEVEGKNLPSDV
CHHHHHHHHHHCCEEEEECCHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNSEEHIFIGNASNSIKIFNRLKSLSQSNLPLFVTGGPGSGKTFVSNLIASLSGTNPQIF
CCCCCEEEEECCCCHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCEEE
IIDSDHHENQRSLESALSVKDNVYFLFKDFPNFPKENQAYLLKRIRENQNNSRFVFISGK
EEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCCEEEEEECH
EWKQKLEAGQILESLYFEISNFRLDLPDLRERKEDIPLLIKHFLEILSDKYKRKEIRLSE
HHHHHHHHHHHHHHHHHHHHCCEECCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
KLYHILLNYDFPGNIRQLRNLLESMISLFAVRILDVKHLPPQMFETSYVYSEFIEVKTGI
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCC
PLRDYEREIIKKNLILVNGNREKAAKILGISERTIYRKIIEFGLSDEVEGKNLPSDV
CHHHHHHHHHHCCEEEEECCHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]