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The map label for this gene is carA [H]

Identifier: 45359152

GI number: 45359152

Start: 1538219

End: 1539319

Strand: Direct

Name: carA [H]

Synonym: MMP1589

Alternate gene names: 45359152

Gene position: 1538219-1539319 (Clockwise)

Preceding gene: 45359149

Following gene: 45359153

Centisome position: 92.6

GC content: 37.51

Gene sequence:

>1101_bases
ATGTACGGAATTTTAGTTTTGGAAGACGGCACAATTATCCGGGGAGAAGGATTTGGTGCAGAGACTGAAGTCCTCGGTGA
ACTCGTATTTAACACTTCCATGACCGGATACGTTGAAATATTAACTGACCCTTCATACAAAGGCCAGATAATTACAATGA
CGTATCCTTTAGAAGGAAACTACGGTGTCGAAAAGGAATGGTTTGAAAGCGATGGAATTAAAGCAGAAGGATTCGTTGTA
AAAGATATTACTGGAAAAGAACTCGACGAATTTTTAAAAGAATACAATATTCCAGGAATTTCAGGCGTAGACACAAGATA
CATTACAAGAAAAATAAGATCAAAAGGGGTCATTAGATCACTCTTAAAAACGTCCACCAACCCGATAACTAAAGATGAAG
AAACAGAATTACTTAAAAAAGTAGTAGATTATCCAGATATTTCAGAAATTGACCTTGTTCCAGAAGTATCAACTAAAGAA
ACAGTTATATACAACGCAGAAGATGAAAAAACAAGATGTGTTCTTATTGACTGCGGTGTAAAACAGAGCATTGTAGACTG
TCTCGTTGAAAGAGGATGCAGTGTTGTAAAAGTTCCCTACAACTCTAAAAAAGAAGAAATTATATCATACAATCCAGACT
TTGTACTCGTGTCAAATGGCCCTGGAGACCCTGAAAACATGTCTGAAACAGTAGAAACCGTTAAAAATTTAATAGGAATG
CTTCCAGTTACCGGAATTTGTCTTGGGCACCAGATAATTACAATTGCACTTGGAGGAAAAACATACAAGTTAAAATTCGG
TCACAGGGGCGGAAACCAGCCAGTAAAAGATGTTGAATCTGGAAAAGTATACATCACTTCACAAAACCACGGGTTTGCTA
CTGACGATAAAATAGTTCCGGCAGGTTCTGAATTGATGCACATGAACTTAAACGACGATACCGTTGAAGGAATAAGAAAA
CTTGAATCAAGTGACCTCAAAAATACAGTATGGAGTGTTCAGTACCACCCAGAAGCAGGGCCTGGACCACATGATGCAAG
ATTCCTCTTTGATGAAATGGTTGAACTTGGAATTAAATTCAAAGCAGAAAAAGCAAACTAA

Upstream 100 bases:

>100_bases
ACACAAAATAGTTATGACTAATAATTTAAATAACTACTCGAACTAACCTAACTGATAAATAGCATGATAACAAACTTATA
GAAAAATTATGGTGGAATTG

Downstream 100 bases:

>100_bases
CTTTTTCAAAAATACTACTCTTTTAAAAATTTAAGACTATTAAAAATATAATTTTTAGTTTTACAGTGAAATCAAAGGAG
AAACCATGGATACAGAAGTT

Product: carbamoyl phosphate synthase small subunit

Products: NA

Alternate protein names: Carbamoyl-phosphate synthetase glutamine chain [H]

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MYGILVLEDGTIIRGEGFGAETEVLGELVFNTSMTGYVEILTDPSYKGQIITMTYPLEGNYGVEKEWFESDGIKAEGFVV
KDITGKELDEFLKEYNIPGISGVDTRYITRKIRSKGVIRSLLKTSTNPITKDEETELLKKVVDYPDISEIDLVPEVSTKE
TVIYNAEDEKTRCVLIDCGVKQSIVDCLVERGCSVVKVPYNSKKEEIISYNPDFVLVSNGPGDPENMSETVETVKNLIGM
LPVTGICLGHQIITIALGGKTYKLKFGHRGGNQPVKDVESGKVYITSQNHGFATDDKIVPAGSELMHMNLNDDTVEGIRK
LESSDLKNTVWSVQYHPEAGPGPHDARFLFDEMVELGIKFKAEKAN

Sequences:

>Translated_366_residues
MYGILVLEDGTIIRGEGFGAETEVLGELVFNTSMTGYVEILTDPSYKGQIITMTYPLEGNYGVEKEWFESDGIKAEGFVV
KDITGKELDEFLKEYNIPGISGVDTRYITRKIRSKGVIRSLLKTSTNPITKDEETELLKKVVDYPDISEIDLVPEVSTKE
TVIYNAEDEKTRCVLIDCGVKQSIVDCLVERGCSVVKVPYNSKKEEIISYNPDFVLVSNGPGDPENMSETVETVKNLIGM
LPVTGICLGHQIITIALGGKTYKLKFGHRGGNQPVKDVESGKVYITSQNHGFATDDKIVPAGSELMHMNLNDDTVEGIRK
LESSDLKNTVWSVQYHPEAGPGPHDARFLFDEMVELGIKFKAEKAN
>Mature_366_residues
MYGILVLEDGTIIRGEGFGAETEVLGELVFNTSMTGYVEILTDPSYKGQIITMTYPLEGNYGVEKEWFESDGIKAEGFVV
KDITGKELDEFLKEYNIPGISGVDTRYITRKIRSKGVIRSLLKTSTNPITKDEETELLKKVVDYPDISEIDLVPEVSTKE
TVIYNAEDEKTRCVLIDCGVKQSIVDCLVERGCSVVKVPYNSKKEEIISYNPDFVLVSNGPGDPENMSETVETVKNLIGM
LPVTGICLGHQIITIALGGKTYKLKFGHRGGNQPVKDVESGKVYITSQNHGFATDDKIVPAGSELMHMNLNDDTVEGIRK
LESSDLKNTVWSVQYHPEAGPGPHDARFLFDEMVELGIKFKAEKAN

Specific function: Arginine biosynthesis. Pyrimidine biosynthesis; first step. [C]

COG id: COG0505

COG function: function code EF; Carbamoylphosphate synthase small subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI18105007, Length=374, Percent_Identity=39.572192513369, Blast_Score=265, Evalue=6e-71,
Organism=Homo sapiens, GI21361331, Length=379, Percent_Identity=37.467018469657, Blast_Score=241, Evalue=9e-64,
Organism=Homo sapiens, GI169790915, Length=379, Percent_Identity=37.467018469657, Blast_Score=241, Evalue=1e-63,
Organism=Escherichia coli, GI1786215, Length=378, Percent_Identity=41.5343915343915, Blast_Score=293, Evalue=1e-80,
Organism=Caenorhabditis elegans, GI193204318, Length=373, Percent_Identity=41.2868632707775, Blast_Score=260, Evalue=8e-70,
Organism=Saccharomyces cerevisiae, GI6322331, Length=396, Percent_Identity=37.8787878787879, Blast_Score=244, Evalue=2e-65,
Organism=Saccharomyces cerevisiae, GI6324878, Length=377, Percent_Identity=36.0742705570292, Blast_Score=229, Evalue=4e-61,
Organism=Drosophila melanogaster, GI45555749, Length=381, Percent_Identity=37.2703412073491, Blast_Score=239, Evalue=2e-63,
Organism=Drosophila melanogaster, GI24642586, Length=381, Percent_Identity=38.0577427821522, Blast_Score=239, Evalue=2e-63,

Paralogues:

None

Copy number: 620 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2599 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR006274
- InterPro:   IPR002474
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991 [H]

Pfam domain/function: PF00988 CPSase_sm_chain; PF00117 GATase [H]

EC number: =6.3.5.5 [H]

Molecular weight: Translated: 40519; Mature: 40519

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYGILVLEDGTIIRGEGFGAETEVLGELVFNTSMTGYVEILTDPSYKGQIITMTYPLEGN
CEEEEEEECCCEEECCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCEEEEEEEECCCC
YGVEKEWFESDGIKAEGFVVKDITGKELDEFLKEYNIPGISGVDTRYITRKIRSKGVIRS
CCCCHHHHCCCCCEECCEEEECCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
LLKTSTNPITKDEETELLKKVVDYPDISEIDLVPEVSTKETVIYNAEDEKTRCVLIDCGV
HHHCCCCCCCCCHHHHHHHHHHCCCCCCCEECCCCCCCCCEEEECCCCCCCEEEEEECCC
KQSIVDCLVERGCSVVKVPYNSKKEEIISYNPDFVLVSNGPGDPENMSETVETVKNLIGM
HHHHHHHHHHCCCCEEECCCCCCCCHHEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHH
LPVTGICLGHQIITIALGGKTYKLKFGHRGGNQPVKDVESGKVYITSQNHGFATDDKIVP
HHHHHHHHCCEEEEEEECCEEEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCC
AGSELMHMNLNDDTVEGIRKLESSDLKNTVWSVQYHPEAGPGPHDARFLFDEMVELGIKF
CCCCEEEECCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCEE
KAEKAN
EECCCC
>Mature Secondary Structure
MYGILVLEDGTIIRGEGFGAETEVLGELVFNTSMTGYVEILTDPSYKGQIITMTYPLEGN
CEEEEEEECCCEEECCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCEEEEEEEECCCC
YGVEKEWFESDGIKAEGFVVKDITGKELDEFLKEYNIPGISGVDTRYITRKIRSKGVIRS
CCCCHHHHCCCCCEECCEEEECCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
LLKTSTNPITKDEETELLKKVVDYPDISEIDLVPEVSTKETVIYNAEDEKTRCVLIDCGV
HHHCCCCCCCCCHHHHHHHHHHCCCCCCCEECCCCCCCCCEEEECCCCCCCEEEEEECCC
KQSIVDCLVERGCSVVKVPYNSKKEEIISYNPDFVLVSNGPGDPENMSETVETVKNLIGM
HHHHHHHHHHCCCCEEECCCCCCCCHHEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHH
LPVTGICLGHQIITIALGGKTYKLKFGHRGGNQPVKDVESGKVYITSQNHGFATDDKIVP
HHHHHHHHCCEEEEEEECCEEEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCC
AGSELMHMNLNDDTVEGIRKLESSDLKNTVWSVQYHPEAGPGPHDARFLFDEMVELGIKF
CCCCEEEECCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCEE
KAEKAN
EECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA