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The map label for this gene is mtrA

Identifier: 45359127

GI number: 45359127

Start: 1517711

End: 1518430

Strand: Direct

Name: mtrA

Synonym: MMP1564

Alternate gene names: 45359127

Gene position: 1517711-1518430 (Clockwise)

Preceding gene: 45359126

Following gene: 45359128

Centisome position: 91.37

GC content: 39.86

Gene sequence:

>720_bases
ATGGCAGATAAAAAAGCCCCAGCAGCAGGATGGCCTGTTGCTAACGGTGAATACGTAGTGGGTAACCCTGAAAGCTGTGT
TGCAGTAGTTACACTCGGTTCCCACGGTTTGGACCAGGCTGCAATTGACGCTGGTGCAGCTATTTCAGGACCATGCCACA
CAGAAAACTTAGGAATTGAAAAAGTTGTTGCAAACTACATTTCAAACCCGAACATTAGATTTATGGTAATTACTGGATCA
GAAGTTCAAGGACACATTACTGGACAATGTATCAAAGCATTATATGAAAACGGAATTGGTGACGATGGTGGTATCATCGG
AGCTAAAGGAGCTATTCCTTTCATGGAAAATGTAGGAACAGAACCAGTTGGAAGACTTCAAAGCCAAATCGTTGAATGCA
TTGATTTAATCGATGTTGAAGACACTGGAAAAATTTCAGATGCAATCAAAAACTGTATCTCAAAAGACCCAGGAGCATTT
GAAGAAGAACCTATGGTTATTGAATTAGAAGGTGGCGCAGCTGCTGCTGGTGAAGAATCCACTTCAATTAAACCTACTTC
ACCTGAAATGGCGTTATTAGAAGCTAGAATGAGAATTGTCTCCGAAAAAATGAATGAAGCTGCAATGATTGCTAAATTTA
ACTCAGGATACTACAACGGAAAAATCCAAGGTATTGCAATAGGATTGTTCCTTTCAATTGTGATATTCTCATTACTCTAA

Upstream 100 bases:

>100_bases
TTTCTGGGTAACAATGGCAGTTCTTGTGCTTGTAACTATATTGGCTGTTAAAATGAATCTAAGCCTAATAGGGTTGTAAT
CTGAATAGGAGGTGCAGACA

Downstream 100 bases:

>100_bases
GGAGGAGGTGCAGACAATGGCAGATAAAAAAGCCCCAGCAGCAGGATGGCCTGTTGCTAACGGTGAATACGTAGTGGGTA
ACCCTGAAAGCTGTGTTGCA

Product: tetrahydromethanopterin S-methyltransferase subunit A

Products: NA

Alternate protein names: N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit A

Number of amino acids: Translated: 239; Mature: 238

Protein sequence:

>239_residues
MADKKAPAAGWPVANGEYVVGNPESCVAVVTLGSHGLDQAAIDAGAAISGPCHTENLGIEKVVANYISNPNIRFMVITGS
EVQGHITGQCIKALYENGIGDDGGIIGAKGAIPFMENVGTEPVGRLQSQIVECIDLIDVEDTGKISDAIKNCISKDPGAF
EEEPMVIELEGGAAAAGEESTSIKPTSPEMALLEARMRIVSEKMNEAAMIAKFNSGYYNGKIQGIAIGLFLSIVIFSLL

Sequences:

>Translated_239_residues
MADKKAPAAGWPVANGEYVVGNPESCVAVVTLGSHGLDQAAIDAGAAISGPCHTENLGIEKVVANYISNPNIRFMVITGS
EVQGHITGQCIKALYENGIGDDGGIIGAKGAIPFMENVGTEPVGRLQSQIVECIDLIDVEDTGKISDAIKNCISKDPGAF
EEEPMVIELEGGAAAAGEESTSIKPTSPEMALLEARMRIVSEKMNEAAMIAKFNSGYYNGKIQGIAIGLFLSIVIFSLL
>Mature_238_residues
ADKKAPAAGWPVANGEYVVGNPESCVAVVTLGSHGLDQAAIDAGAAISGPCHTENLGIEKVVANYISNPNIRFMVITGSE
VQGHITGQCIKALYENGIGDDGGIIGAKGAIPFMENVGTEPVGRLQSQIVECIDLIDVEDTGKISDAIKNCISKDPGAFE
EEPMVIELEGGAAAAGEESTSIKPTSPEMALLEARMRIVSEKMNEAAMIAKFNSGYYNGKIQGIAIGLFLSIVIFSLL

Specific function: Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step

COG id: COG4063

COG function: function code H; Tetrahydromethanopterin S-methyltransferase, subunit A

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MtrA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTRA_METMP (Q6LWZ0)

Other databases:

- EMBL:   BX950229
- RefSeq:   NP_988684.1
- GeneID:   2761895
- GenomeReviews:   BX950229_GR
- KEGG:   mmp:MMP1564
- NMPDR:   fig|267377.1.peg.1564
- HOGENOM:   HBG542039
- OMA:   ARMKIVS
- ProtClustDB:   PRK00964
- BioCyc:   MMAR267377:MMP1564-MONOMER
- BRENDA:   2.1.1.86
- GO:   GO:0005737
- GO:   GO:0015948
- HAMAP:   MF_01093
- InterPro:   IPR005778
- InterPro:   IPR013340
- TIGRFAMs:   TIGR01111

Pfam domain/function: PF04208 MtrA

EC number: =2.1.1.86

Molecular weight: Translated: 24955; Mature: 24824

Theoretical pI: Translated: 4.25; Mature: 4.25

Prosite motif: NA

Important sites: BINDING 85-85

Signals:

None

Transmembrane regions:

HASH(0xe52fc38)-;

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADKKAPAAGWPVANGEYVVGNPESCVAVVTLGSHGLDQAAIDAGAAISGPCHTENLGIE
CCCCCCCCCCCCCCCCCEEECCCCCEEEEEEECCCCCCHHHHCCCCCCCCCCCCCCCCHH
KVVANYISNPNIRFMVITGSEVQGHITGQCIKALYENGIGDDGGIIGAKGAIPFMENVGT
HHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCEEECCCCCCHHHHCCC
EPVGRLQSQIVECIDLIDVEDTGKISDAIKNCISKDPGAFEEEPMVIELEGGAAAAGEES
CHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCC
TSIKPTSPEMALLEARMRIVSEKMNEAAMIAKFNSGYYNGKIQGIAIGLFLSIVIFSLL
CCCCCCCCHHHHHHHHHHHHHHHHCHHEEEEEECCCEECCEEEHHHHHHHHHHHHHHHH
>Mature Secondary Structure 
ADKKAPAAGWPVANGEYVVGNPESCVAVVTLGSHGLDQAAIDAGAAISGPCHTENLGIE
CCCCCCCCCCCCCCCCEEECCCCCEEEEEEECCCCCCHHHHCCCCCCCCCCCCCCCCHH
KVVANYISNPNIRFMVITGSEVQGHITGQCIKALYENGIGDDGGIIGAKGAIPFMENVGT
HHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCEEECCCCCCHHHHCCC
EPVGRLQSQIVECIDLIDVEDTGKISDAIKNCISKDPGAFEEEPMVIELEGGAAAAGEES
CHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCC
TSIKPTSPEMALLEARMRIVSEKMNEAAMIAKFNSGYYNGKIQGIAIGLFLSIVIFSLL
CCCCCCCCHHHHHHHHHHHHHHHHCHHEEEEEECCCEECCEEEHHHHHHHHHHHHHHHH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA