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The map label for this gene is mtrD

Identifier: 45359124

GI number: 45359124

Start: 1515819

End: 1516526

Strand: Direct

Name: mtrD

Synonym: MMP1561

Alternate gene names: 45359124

Gene position: 1515819-1516526 (Clockwise)

Preceding gene: 45359123

Following gene: 45359125

Centisome position: 91.25

GC content: 42.94

Gene sequence:

>708_bases
ATGGATGCTACAAGCTTTATATTACCTCTTGCGGAAATAACCATTGCGGGAGCGATTATCAACGCAAGTGTTCACTTCGT
TCCAGTAGGTGGTGCTCCAGCAGCGATGGCTACTTCAACAGGGGTAGGTACAGGTACAACACAGTTAGCAGCAGGTGCAG
GTTTTACCGGACTCTTAGCTGCAGCTGCAATGGCTTCGCAAGCAGGTGTTTCACTGTCTAATCCAGTTCACATGTTATTA
ATCATGTTATCTGGTGCTGTCGGTGCAATGATCATGTTAGGTCTTACAATGTTAATTGGTCAGATTATCTATGTATACGG
TATTGGTATCGTCCCTGCAGCAGATAAATGTGAAAAAGACCCTATTACGGGAGATATTCAAAAACCATACATTACACCAG
GTACAACAGGACACGGTATTCCAACCGTATGTTTTGTAAGTGGTACAATTGGTGCAGCTCTTGGTGGTCTTGGTGGTGCT
CTTGCATACATCGCACTCCAGCAGTTAGGATTTGCTGCAGCTATTGCAGGTGTATTGGCAGTTGGATTCTTCTTCATGAA
CGCAGTATTAGCTTCATACAATATTGGTGGTACAATCGAAGGATTCCACGACCCTAAATTTAAGAAAATGCCAAACGGAG
TTATTGCTTCATTTGTTTCTTCATTAATCGCAGGAGCAGTATTAATTGGAATGGCTATGGGACTTTAA

Upstream 100 bases:

>100_bases
TGGCCGTTGCAGCAGTTATCAACAGGAAACTCGAGGTATATGCTAGAAACAAATACGGACCATACAGAAATTAATTAAAA
TAAGGAAGATTGGTGATATT

Downstream 100 bases:

>100_bases
GTCTACCATGGTTTTCAAAAATATTTGAGGTGTAATTATGTCACATGGTGGTGGAGGACACGCAGCAGAGCTTTTTCCTG
AAGATCAGGTTTTAGCTATC

Product: tetrahydromethanopterin S-methyltransferase subunit D

Products: NA

Alternate protein names: N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit D

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MDATSFILPLAEITIAGAIINASVHFVPVGGAPAAMATSTGVGTGTTQLAAGAGFTGLLAAAAMASQAGVSLSNPVHMLL
IMLSGAVGAMIMLGLTMLIGQIIYVYGIGIVPAADKCEKDPITGDIQKPYITPGTTGHGIPTVCFVSGTIGAALGGLGGA
LAYIALQQLGFAAAIAGVLAVGFFFMNAVLASYNIGGTIEGFHDPKFKKMPNGVIASFVSSLIAGAVLIGMAMGL

Sequences:

>Translated_235_residues
MDATSFILPLAEITIAGAIINASVHFVPVGGAPAAMATSTGVGTGTTQLAAGAGFTGLLAAAAMASQAGVSLSNPVHMLL
IMLSGAVGAMIMLGLTMLIGQIIYVYGIGIVPAADKCEKDPITGDIQKPYITPGTTGHGIPTVCFVSGTIGAALGGLGGA
LAYIALQQLGFAAAIAGVLAVGFFFMNAVLASYNIGGTIEGFHDPKFKKMPNGVIASFVSSLIAGAVLIGMAMGL
>Mature_235_residues
MDATSFILPLAEITIAGAIINASVHFVPVGGAPAAMATSTGVGTGTTQLAAGAGFTGLLAAAAMASQAGVSLSNPVHMLL
IMLSGAVGAMIMLGLTMLIGQIIYVYGIGIVPAADKCEKDPITGDIQKPYITPGTTGHGIPTVCFVSGTIGAALGGLGGA
LAYIALQQLGFAAAIAGVLAVGFFFMNAVLASYNIGGTIEGFHDPKFKKMPNGVIASFVSSLIAGAVLIGMAMGL

Specific function: Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step

COG id: COG4060

COG function: function code H; Tetrahydromethanopterin S-methyltransferase, subunit D

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mtrD family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTRD_METMP (Q6LWZ3)

Other databases:

- EMBL:   BX950229
- RefSeq:   NP_988681.1
- GeneID:   2761421
- GenomeReviews:   BX950229_GR
- KEGG:   mmp:MMP1561
- NMPDR:   fig|267377.1.peg.1561
- HOGENOM:   HBG551221
- OMA:   HFVPVGG
- ProtClustDB:   PRK00968
- BioCyc:   MMAR267377:MMP1561-MONOMER
- BRENDA:   2.1.1.86
- GO:   GO:0005737
- GO:   GO:0015948
- HAMAP:   MF_01097
- InterPro:   IPR005779
- PIRSF:   PIRSF016552
- ProDom:   PD013594
- TIGRFAMs:   TIGR01112

Pfam domain/function: PF04207 MtrD

EC number: =2.1.1.86

Molecular weight: Translated: 23230; Mature: 23230

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xe0328d0)-; HASH(0xe54e45c)-; HASH(0xef35f6c)-; HASH(0xec05714)-; HASH(0xee69720)-; HASH(0xef6d3a8)-;

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDATSFILPLAEITIAGAIINASVHFVPVGGAPAAMATSTGVGTGTTQLAAGAGFTGLLA
CCCHHHHHHHHHHHHHHHHEECEEEEEECCCCCHHHHCCCCCCCCHHHHHCCCCHHHHHH
AAAMASQAGVSLSNPVHMLLIMLSGAVGAMIMLGLTMLIGQIIYVYGIGIVPAADKCEKD
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
PITGDIQKPYITPGTTGHGIPTVCFVSGTIGAALGGLGGALAYIALQQLGFAAAIAGVLA
CCCCCCCCCEECCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGFFFMNAVLASYNIGGTIEGFHDPKFKKMPNGVIASFVSSLIAGAVLIGMAMGL
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MDATSFILPLAEITIAGAIINASVHFVPVGGAPAAMATSTGVGTGTTQLAAGAGFTGLLA
CCCHHHHHHHHHHHHHHHHEECEEEEEECCCCCHHHHCCCCCCCCHHHHHCCCCHHHHHH
AAAMASQAGVSLSNPVHMLLIMLSGAVGAMIMLGLTMLIGQIIYVYGIGIVPAADKCEKD
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
PITGDIQKPYITPGTTGHGIPTVCFVSGTIGAALGGLGGALAYIALQQLGFAAAIAGVLA
CCCCCCCCCEECCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGFFFMNAVLASYNIGGTIEGFHDPKFKKMPNGVIASFVSSLIAGAVLIGMAMGL
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA