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The map label for this gene is ahpC [C]

Identifier: 45358737

GI number: 45358737

Start: 1156960

End: 1157613

Strand: Direct

Name: ahpC [C]

Synonym: MMP1174

Alternate gene names: 45358737

Gene position: 1156960-1157613 (Clockwise)

Preceding gene: 45358734

Following gene: 45358738

Centisome position: 69.65

GC content: 37.0

Gene sequence:

>654_bases
TTGGTAGTAATCGGAGAAAAATTCCCAGAAGTTGAAGTTACAACAACTCATGGAAAGCTAAAATTACCGGAACATTATAT
TGAATCTGGAAAATGGTTTGTTTTATTCAGCCACCCTGGAGACTTCACACCAGTGTGTACTACGGAGTTTGTCGCATTTC
AAAAAAGATACGATCAGTTCAGAGAATTAAACACTGAATTAATTGGTTTGAGTATCGATCAGGTATTCAGCCACATAAAA
TGGGTAGAATGGATAAAAGAAAAATTAGACGTTGACATAGAATTTCCAATAATTGCTGATGACAGGGGAGAGTTAGCAGT
GAAACTTGGAATGATAAGCCCTTACAAAGGAAATAATACTGTTAGGGCAGTATTTGTAGTTGATGCTACAGGAACAATCC
GTGCAATAATTTACTACCCTCAAGAAGTTGGTAGAAATATGGACGAAATTGTAAGGCTTGTAAAAGCACTTCAAACCGCG
GATAAAGGCTATGCGACACCTGCAAACTGGCCAAATAATGACTTTTTAAATGAAAAAGTAATTGTACCTCCTGCAAATAA
CATGGACGCTAGAAAAAAACGACTTGAAGCATGCAAAAGTGGAGAACTTGAAGGTTACGACTGGTGGTTCTGCTATACGG
ATTTAAAAGAATAA

Upstream 100 bases:

>100_bases
AGATTTCAAACTAAAATTTATTTTTAAAAACCGGTCAAAACATATATATTACGCAAATAACGAAGTTTATATGTACATTA
AAAAATCTTGAGGGGATAAT

Downstream 100 bases:

>100_bases
TTCTTTTTTTTATTTTTTTAACTGAGGATATATTTAATAATTTAAATATATTGTTAAGTATGATTTTTATAAAAATAATA
TGAATATTTATATAAGTTTT

Product: peroxiredoxin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MVVIGEKFPEVEVTTTHGKLKLPEHYIESGKWFVLFSHPGDFTPVCTTEFVAFQKRYDQFRELNTELIGLSIDQVFSHIK
WVEWIKEKLDVDIEFPIIADDRGELAVKLGMISPYKGNNTVRAVFVVDATGTIRAIIYYPQEVGRNMDEIVRLVKALQTA
DKGYATPANWPNNDFLNEKVIVPPANNMDARKKRLEACKSGELEGYDWWFCYTDLKE

Sequences:

>Translated_217_residues
MVVIGEKFPEVEVTTTHGKLKLPEHYIESGKWFVLFSHPGDFTPVCTTEFVAFQKRYDQFRELNTELIGLSIDQVFSHIK
WVEWIKEKLDVDIEFPIIADDRGELAVKLGMISPYKGNNTVRAVFVVDATGTIRAIIYYPQEVGRNMDEIVRLVKALQTA
DKGYATPANWPNNDFLNEKVIVPPANNMDARKKRLEACKSGELEGYDWWFCYTDLKE
>Mature_217_residues
MVVIGEKFPEVEVTTTHGKLKLPEHYIESGKWFVLFSHPGDFTPVCTTEFVAFQKRYDQFRELNTELIGLSIDQVFSHIK
WVEWIKEKLDVDIEFPIIADDRGELAVKLGMISPYKGNNTVRAVFVVDATGTIRAIIYYPQEVGRNMDEIVRLVKALQTA
DKGYATPANWPNNDFLNEKVIVPPANNMDARKKRLEACKSGELEGYDWWFCYTDLKE

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758638, Length=222, Percent_Identity=36.4864864864865, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI5453549, Length=172, Percent_Identity=34.8837209302326, Blast_Score=105, Evalue=3e-23,
Organism=Homo sapiens, GI4505591, Length=182, Percent_Identity=34.6153846153846, Blast_Score=104, Evalue=5e-23,
Organism=Homo sapiens, GI32455266, Length=182, Percent_Identity=34.6153846153846, Blast_Score=104, Evalue=5e-23,
Organism=Homo sapiens, GI32455264, Length=182, Percent_Identity=34.6153846153846, Blast_Score=104, Evalue=5e-23,
Organism=Homo sapiens, GI32189392, Length=181, Percent_Identity=34.2541436464088, Blast_Score=104, Evalue=8e-23,
Organism=Homo sapiens, GI5802974, Length=143, Percent_Identity=33.5664335664336, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI32483377, Length=143, Percent_Identity=33.5664335664336, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI33188454, Length=81, Percent_Identity=40.7407407407407, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1786822, Length=143, Percent_Identity=31.4685314685315, Blast_Score=75, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17554494, Length=155, Percent_Identity=36.1290322580645, Blast_Score=107, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI25153706, Length=182, Percent_Identity=34.6153846153846, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI32565831, Length=154, Percent_Identity=35.0649350649351, Blast_Score=99, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI193204376, Length=154, Percent_Identity=35.0649350649351, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6319407, Length=202, Percent_Identity=43.0693069306931, Blast_Score=138, Evalue=8e-34,
Organism=Saccharomyces cerevisiae, GI6323613, Length=143, Percent_Identity=34.965034965035, Blast_Score=81, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6320661, Length=143, Percent_Identity=32.1678321678322, Blast_Score=75, Evalue=7e-15,
Organism=Drosophila melanogaster, GI17975518, Length=177, Percent_Identity=41.2429378531073, Blast_Score=132, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24652436, Length=177, Percent_Identity=41.2429378531073, Blast_Score=132, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24652434, Length=177, Percent_Identity=41.2429378531073, Blast_Score=132, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24581278, Length=175, Percent_Identity=43.4285714285714, Blast_Score=128, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24656348, Length=180, Percent_Identity=34.4444444444444, Blast_Score=104, Evalue=5e-23,
Organism=Drosophila melanogaster, GI17864676, Length=180, Percent_Identity=34.4444444444444, Blast_Score=104, Evalue=5e-23,
Organism=Drosophila melanogaster, GI17738015, Length=148, Percent_Identity=36.4864864864865, Blast_Score=104, Evalue=5e-23,
Organism=Drosophila melanogaster, GI17157991, Length=143, Percent_Identity=37.0629370629371, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24641739, Length=143, Percent_Identity=37.0629370629371, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI21357347, Length=143, Percent_Identity=34.2657342657343, Blast_Score=92, Evalue=2e-19,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 24969; Mature: 24969

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVIGEKFPEVEVTTTHGKLKLPEHYIESGKWFVLFSHPGDFTPVCTTEFVAFQKRYDQF
CEEECCCCCCEEEEECCCCEECCHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHH
RELNTELIGLSIDQVFSHIKWVEWIKEKLDVDIEFPIIADDRGELAVKLGMISPYKGNNT
HHCCHHEEEEEHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEEECCCCCCCCCE
VRAVFVVDATGTIRAIIYYPQEVGRNMDEIVRLVKALQTADKGYATPANWPNNDFLNEKV
EEEEEEEECCCCEEEEEEECHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEE
IVPPANNMDARKKRLEACKSGELEGYDWWFCYTDLKE
EECCCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCC
>Mature Secondary Structure
MVVIGEKFPEVEVTTTHGKLKLPEHYIESGKWFVLFSHPGDFTPVCTTEFVAFQKRYDQF
CEEECCCCCCEEEEECCCCEECCHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHH
RELNTELIGLSIDQVFSHIKWVEWIKEKLDVDIEFPIIADDRGELAVKLGMISPYKGNNT
HHCCHHEEEEEHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEEECCCCCCCCCE
VRAVFVVDATGTIRAIIYYPQEVGRNMDEIVRLVKALQTADKGYATPANWPNNDFLNEKV
EEEEEEEECCCCEEEEEEECHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEE
IVPPANNMDARKKRLEACKSGELEGYDWWFCYTDLKE
EECCCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA