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The map label for this gene is cysS [H]

Identifier: 45358623

GI number: 45358623

Start: 1051556

End: 1052986

Strand: Direct

Name: cysS [H]

Synonym: MMP1060

Alternate gene names: 45358623

Gene position: 1051556-1052986 (Clockwise)

Preceding gene: 45358622

Following gene: 45358624

Centisome position: 63.3

GC content: 30.68

Gene sequence:

>1431_bases
ATGTTAAAAGTTTACAATACACTCACACGATGCGAAGAAGAATTTAAAACTTTAAATGAAAAAGAGGTTAAAATGTACGT
TTGTGGCCCGACAGTCTATGATAACACCCATTTAGGGCACGGTCGAACTTACGTTTCATTTGATATTATTCGTAGATACC
TCGAACATATGGGTTATACAGTAAATCTCGTTATAAATTTTACAGATATTGATGATAAAATTATTAAAAGAGCATATGAA
AAAGAAAAAGATCCAAAAGAAATTTCAGAACAATTTATAAAGGTATTTTTAGATGATATGGCCACATTAAAAGTAAAACC
TGCAGATATCTATCCAAAAGTTACAGAACATATTTCTGAAATTATTGCTTTTATTGAAAAGTTGATTGAAAAGGGTTTTG
CATACAAAACTGAAGACGGCGTTTATTTCGAAGTTAAAAAATTTAAAAACTATGGAAAATTAAGTAATATCAATTTAGAA
GATTTGGTTTCGGGAGCTCGAATTGAAACTTCTGAAAAAAAGAAAAACCAAAAAGACTTTGCACTCTGGAAAACTGCAAA
ACCTGGAGAACCTAAATGGGAAAGTCCTTTTGGGAGTGGAAGGCCCGGATGGCACATCGAATGCTCTGCAATGAGTTCAA
AATATCTTGGAGAACAGTTCGATATACACGGAGGCGGACGAGATTTATCATTTCCGCACCACGAAAATGAGATTGCCCAG
AGTTCAGCATATTCTGGAAAAGACTGGGTTAATTACTGGTTGCATACTGGCTTTGTAATGGTTAACGGAGAAAAAATGAG
TAAATCTTTGGGCAATTTTGTAACTATTGGTGACATTTCAAAAGAATACAGTCCAGAAATCTTGAGGTTTTTCTTCATTC
AAAGGCACTACAGAAGCCCAATTGATTATACCGCTGAATCTATGAATCACGTTAAAAACAACCTTGAAAAAATTTACAAC
GTAATTGAAAACATAAGAATATCACTTGAAAAATCTGAAAAATCAAGAACATGGGATGAAAATGAATTTTTACTCTACGA
TATTTTAAAAAATTCAAAAAATAATTTTTATAACGCAATGAACTCAGATTTTAACACAGTTAAAGCATTGAAATCAGTAT
TTGAAGTTTCTAATGGAGTTAATAAATATTTAAGTTTAACAAAAACTCCTAGTGAAGGTTTACTATTAAAAGCACTTGAT
TTCTATAAAATAATTGGAGAAATATTTGGATTATTTGAAAATTACTTTAAAGAATCATCTGACTCAGATGAAGAAGAATT
TGTTACATTTTTAATTGAATTGAGGTCTGATGTAAGGCTTCAAAAAAATTACGAAATGTCTGACAAAATACGGGATGGTT
TGAAAAATTTAGGATATCAAATTGAGGACAACCCAAAAGAAGGAACAGTATTTAAAAAAATAAATATTTAA

Upstream 100 bases:

>100_bases
GCTCGCGGAATTCTTAAAAAAGAAGGAATTACAGATATTTTTAAAGATGAAAATACAAATTGGCAGGAAAAAGTAGAAAG
CATGAAATAAAGGGGAAGTT

Downstream 100 bases:

>100_bases
TTTTCGAGTGGTATTTTGGACGAAAATTCCTACAAAACACTTAAATCTTTTTCAAAAGTAGAACTGGTCTTTAAAGGTTC
ATTATTCCTTGGTTATGGAA

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 476; Mature: 476

Protein sequence:

>476_residues
MLKVYNTLTRCEEEFKTLNEKEVKMYVCGPTVYDNTHLGHGRTYVSFDIIRRYLEHMGYTVNLVINFTDIDDKIIKRAYE
KEKDPKEISEQFIKVFLDDMATLKVKPADIYPKVTEHISEIIAFIEKLIEKGFAYKTEDGVYFEVKKFKNYGKLSNINLE
DLVSGARIETSEKKKNQKDFALWKTAKPGEPKWESPFGSGRPGWHIECSAMSSKYLGEQFDIHGGGRDLSFPHHENEIAQ
SSAYSGKDWVNYWLHTGFVMVNGEKMSKSLGNFVTIGDISKEYSPEILRFFFIQRHYRSPIDYTAESMNHVKNNLEKIYN
VIENIRISLEKSEKSRTWDENEFLLYDILKNSKNNFYNAMNSDFNTVKALKSVFEVSNGVNKYLSLTKTPSEGLLLKALD
FYKIIGEIFGLFENYFKESSDSDEEEFVTFLIELRSDVRLQKNYEMSDKIRDGLKNLGYQIEDNPKEGTVFKKINI

Sequences:

>Translated_476_residues
MLKVYNTLTRCEEEFKTLNEKEVKMYVCGPTVYDNTHLGHGRTYVSFDIIRRYLEHMGYTVNLVINFTDIDDKIIKRAYE
KEKDPKEISEQFIKVFLDDMATLKVKPADIYPKVTEHISEIIAFIEKLIEKGFAYKTEDGVYFEVKKFKNYGKLSNINLE
DLVSGARIETSEKKKNQKDFALWKTAKPGEPKWESPFGSGRPGWHIECSAMSSKYLGEQFDIHGGGRDLSFPHHENEIAQ
SSAYSGKDWVNYWLHTGFVMVNGEKMSKSLGNFVTIGDISKEYSPEILRFFFIQRHYRSPIDYTAESMNHVKNNLEKIYN
VIENIRISLEKSEKSRTWDENEFLLYDILKNSKNNFYNAMNSDFNTVKALKSVFEVSNGVNKYLSLTKTPSEGLLLKALD
FYKIIGEIFGLFENYFKESSDSDEEEFVTFLIELRSDVRLQKNYEMSDKIRDGLKNLGYQIEDNPKEGTVFKKINI
>Mature_476_residues
MLKVYNTLTRCEEEFKTLNEKEVKMYVCGPTVYDNTHLGHGRTYVSFDIIRRYLEHMGYTVNLVINFTDIDDKIIKRAYE
KEKDPKEISEQFIKVFLDDMATLKVKPADIYPKVTEHISEIIAFIEKLIEKGFAYKTEDGVYFEVKKFKNYGKLSNINLE
DLVSGARIETSEKKKNQKDFALWKTAKPGEPKWESPFGSGRPGWHIECSAMSSKYLGEQFDIHGGGRDLSFPHHENEIAQ
SSAYSGKDWVNYWLHTGFVMVNGEKMSKSLGNFVTIGDISKEYSPEILRFFFIQRHYRSPIDYTAESMNHVKNNLEKIYN
VIENIRISLEKSEKSRTWDENEFLLYDILKNSKNNFYNAMNSDFNTVKALKSVFEVSNGVNKYLSLTKTPSEGLLLKALD
FYKIIGEIFGLFENYFKESSDSDEEEFVTFLIELRSDVRLQKNYEMSDKIRDGLKNLGYQIEDNPKEGTVFKKINI

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=504, Percent_Identity=37.6984126984127, Blast_Score=320, Evalue=2e-87,
Organism=Homo sapiens, GI303304987, Length=424, Percent_Identity=33.7264150943396, Blast_Score=231, Evalue=2e-60,
Organism=Homo sapiens, GI62240992, Length=424, Percent_Identity=33.7264150943396, Blast_Score=230, Evalue=2e-60,
Organism=Homo sapiens, GI21269877, Length=424, Percent_Identity=33.7264150943396, Blast_Score=230, Evalue=3e-60,
Organism=Homo sapiens, GI10835051, Length=424, Percent_Identity=33.7264150943396, Blast_Score=229, Evalue=3e-60,
Organism=Escherichia coli, GI1786737, Length=476, Percent_Identity=42.2268907563025, Blast_Score=385, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI17509795, Length=446, Percent_Identity=33.1838565022422, Blast_Score=211, Evalue=8e-55,
Organism=Caenorhabditis elegans, GI17509797, Length=446, Percent_Identity=33.1838565022422, Blast_Score=211, Evalue=8e-55,
Organism=Saccharomyces cerevisiae, GI6324082, Length=309, Percent_Identity=41.1003236245955, Blast_Score=223, Evalue=5e-59,
Organism=Drosophila melanogaster, GI19922218, Length=502, Percent_Identity=36.2549800796813, Blast_Score=283, Evalue=1e-76,
Organism=Drosophila melanogaster, GI19922364, Length=415, Percent_Identity=35.6626506024096, Blast_Score=225, Evalue=4e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 55409; Mature: 55409

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKVYNTLTRCEEEFKTLNEKEVKMYVCGPTVYDNTHLGHGRTYVSFDIIRRYLEHMGYT
CCCHHHHHHHHHHHHHCCCCCCEEEEEECCEEECCCCCCCCCEEEEHHHHHHHHHHCCCE
VNLVINFTDIDDKIIKRAYEKEKDPKEISEQFIKVFLDDMATLKVKPADIYPKVTEHISE
EEEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHH
IIAFIEKLIEKGFAYKTEDGVYFEVKKFKNYGKLSNINLEDLVSGARIETSEKKKNQKDF
HHHHHHHHHHCCCCEECCCCEEEEEHHHHCCCCCCCCCHHHHHCCCCCCCHHHHCCCCHH
ALWKTAKPGEPKWESPFGSGRPGWHIECSAMSSKYLGEQFDIHGGGRDLSFPHHENEIAQ
EEEECCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHCCCEEEECCCCCCCCCCCCHHHHHH
SSAYSGKDWVNYWLHTGFVMVNGEKMSKSLGNFVTIGDISKEYSPEILRFFFIQRHYRSP
HCCCCCHHHHHHHHHCCEEEEECHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHCCC
IDYTAESMNHVKNNLEKIYNVIENIRISLEKSEKSRTWDENEFLLYDILKNSKNNFYNAM
CHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCEEEHHHHHCCCCHHHHHH
NSDFNTVKALKSVFEVSNGVNKYLSLTKTPSEGLLLKALDFYKIIGEIFGLFENYFKESS
CCCHHHHHHHHHHHHHHCCHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
DSDEEEFVTFLIELRSDVRLQKNYEMSDKIRDGLKNLGYQIEDNPKEGTVFKKINI
CCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCEEECCCCCCCCEEEEECC
>Mature Secondary Structure
MLKVYNTLTRCEEEFKTLNEKEVKMYVCGPTVYDNTHLGHGRTYVSFDIIRRYLEHMGYT
CCCHHHHHHHHHHHHHCCCCCCEEEEEECCEEECCCCCCCCCEEEEHHHHHHHHHHCCCE
VNLVINFTDIDDKIIKRAYEKEKDPKEISEQFIKVFLDDMATLKVKPADIYPKVTEHISE
EEEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHH
IIAFIEKLIEKGFAYKTEDGVYFEVKKFKNYGKLSNINLEDLVSGARIETSEKKKNQKDF
HHHHHHHHHHCCCCEECCCCEEEEEHHHHCCCCCCCCCHHHHHCCCCCCCHHHHCCCCHH
ALWKTAKPGEPKWESPFGSGRPGWHIECSAMSSKYLGEQFDIHGGGRDLSFPHHENEIAQ
EEEECCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHCCCEEEECCCCCCCCCCCCHHHHHH
SSAYSGKDWVNYWLHTGFVMVNGEKMSKSLGNFVTIGDISKEYSPEILRFFFIQRHYRSP
HCCCCCHHHHHHHHHCCEEEEECHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHCCC
IDYTAESMNHVKNNLEKIYNVIENIRISLEKSEKSRTWDENEFLLYDILKNSKNNFYNAM
CHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCEEEHHHHHCCCCHHHHHH
NSDFNTVKALKSVFEVSNGVNKYLSLTKTPSEGLLLKALDFYKIIGEIFGLFENYFKESS
CCCHHHHHHHHHHHHHHCCHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
DSDEEEFVTFLIELRSDVRLQKNYEMSDKIRDGLKNLGYQIEDNPKEGTVFKKINI
CCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCEEECCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA