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The map label for this gene is cheB

Identifier: 45358489

GI number: 45358489

Start: 913654

End: 914751

Strand: Direct

Name: cheB

Synonym: MMP0926

Alternate gene names: 45358489

Gene position: 913654-914751 (Clockwise)

Preceding gene: 45358488

Following gene: 45358490

Centisome position: 55.0

GC content: 35.97

Gene sequence:

>1098_bases
ATGAGTAAAATAAAGGTTCTAATTGTAGATGATTCAGCATTTATGAGGAAGGTTTTAGAAGACATTTTAAAATCCGATGA
CGAAATAGAAGTTGTTGCTACTGCAAAAGATGGAAAAGAAGCATTTGAACTTGTGAAAAAATTAGAACCAAATGTAATTA
CCATGGATGTTGAAATGCCGATCATGAATGGAATTGATGCTACAAAGCAGATCATGGCATACAAACCTACCCCTATACTC
ATGCTTTCCGCAGTAACAAAACAGGGCTCAGAAGCTACATTAAAAGCGCTGGATAATGGCGCAGTTGATTTTATAGAAAA
GCCTTCGGGTTCTGTTTCACTGGACATTAGAAAAATCGGGGAAAAAATAATTAAACAGGTTAAAGATGCTTCAAAATCCA
AAGTAAGAATTAAATCATCCCGAATTTTAGAGAATATTAAAAAAGAAAAACAGGATGAAAGCAGTACCCCAAAACCTCAG
GTTGAAAAAACTTCTGGACTTTCTCCTGAAAAATTAAATGATACTGCAATATTAATAGGCTCTTCAACAGGTGGGCCACC
AGTTGTTTCAAGCATAATTTCGAATATTCCTAAAAACACACCTCCAATTTTTATAGTTCAACACATGCCCAAAGGATTTA
CCCGTGTTTTTGCCGAAAGGATGAACAATAATTCAGCAATTACTGTTAAAGAAGCAGAACATGGTGAAATTGTAAAACCC
GACCATGCTTACGTTGCACCAGGCGATTCCCAAATGGTTCTTCAAAAAAGAGGTGGCAATGTATACATCATAATTGATGA
AAATATGCCAAAAATCCATGGAACGAAACCAACCGTGGATGTAACTGCCGAATACGTCACAAAATATTATGGAAAAAACA
CAATTGGCGTACTTTTAACAGGTATCGGAAGAGATGGTGCAAACGGGCTAAAAATGGTAAAAAATAAGGGCGGATATACC
ATTGCACAAAATCAAGACACATGTGTTATTTACGGCATGCCCAAAACAGCAATCGAAATGAATGTAGTCGATAAAGTTAT
GGATCCAATAGATATTCCTTTAGAAATCATTAAATTCGCCAAAAAAATAGGGGGCTGA

Upstream 100 bases:

>100_bases
ATAGATTAATCATTATTCTTGATATCAAAAATTTAATTGACCCGCAAGAATTTTAAATAACCAAAAAAAAATCCCCTAAT
TACCAAAAACAAGTGAAAAC

Downstream 100 bases:

>100_bases
TACCATGGACGATATGGAACAGTATAAAGAACTATTCATGACTGAAGCGGAAGAACATTTGCAATCATTAAATCAAAATA
TGGTTGAACTTGAAAACTGT

Product: response regulator receiver modulated CheB methylesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MSKIKVLIVDDSAFMRKVLEDILKSDDEIEVVATAKDGKEAFELVKKLEPNVITMDVEMPIMNGIDATKQIMAYKPTPIL
MLSAVTKQGSEATLKALDNGAVDFIEKPSGSVSLDIRKIGEKIIKQVKDASKSKVRIKSSRILENIKKEKQDESSTPKPQ
VEKTSGLSPEKLNDTAILIGSSTGGPPVVSSIISNIPKNTPPIFIVQHMPKGFTRVFAERMNNNSAITVKEAEHGEIVKP
DHAYVAPGDSQMVLQKRGGNVYIIIDENMPKIHGTKPTVDVTAEYVTKYYGKNTIGVLLTGIGRDGANGLKMVKNKGGYT
IAQNQDTCVIYGMPKTAIEMNVVDKVMDPIDIPLEIIKFAKKIGG

Sequences:

>Translated_365_residues
MSKIKVLIVDDSAFMRKVLEDILKSDDEIEVVATAKDGKEAFELVKKLEPNVITMDVEMPIMNGIDATKQIMAYKPTPIL
MLSAVTKQGSEATLKALDNGAVDFIEKPSGSVSLDIRKIGEKIIKQVKDASKSKVRIKSSRILENIKKEKQDESSTPKPQ
VEKTSGLSPEKLNDTAILIGSSTGGPPVVSSIISNIPKNTPPIFIVQHMPKGFTRVFAERMNNNSAITVKEAEHGEIVKP
DHAYVAPGDSQMVLQKRGGNVYIIIDENMPKIHGTKPTVDVTAEYVTKYYGKNTIGVLLTGIGRDGANGLKMVKNKGGYT
IAQNQDTCVIYGMPKTAIEMNVVDKVMDPIDIPLEIIKFAKKIGG
>Mature_364_residues
SKIKVLIVDDSAFMRKVLEDILKSDDEIEVVATAKDGKEAFELVKKLEPNVITMDVEMPIMNGIDATKQIMAYKPTPILM
LSAVTKQGSEATLKALDNGAVDFIEKPSGSVSLDIRKIGEKIIKQVKDASKSKVRIKSSRILENIKKEKQDESSTPKPQV
EKTSGLSPEKLNDTAILIGSSTGGPPVVSSIISNIPKNTPPIFIVQHMPKGFTRVFAERMNNNSAITVKEAEHGEIVKPD
HAYVAPGDSQMVLQKRGGNVYIIIDENMPKIHGTKPTVDVTAEYVTKYYGKNTIGVLLTGIGRDGANGLKMVKNKGGYTI
AQNQDTCVIYGMPKTAIEMNVVDKVMDPIDIPLEIIKFAKKIGG

Specific function: Involved in the modulation of the chemotaxis system; catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR

COG id: COG2201

COG function: function code NT; Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain

Homologues:

Organism=Escherichia coli, GI1788192, Length=348, Percent_Identity=42.2413793103448, Blast_Score=284, Evalue=8e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CHEB_METMP (P62647)

Other databases:

- EMBL:   BX950229
- RefSeq:   NP_988046.1
- ProteinModelPortal:   P62647
- SMR:   P62647
- GeneID:   2761703
- GenomeReviews:   BX950229_GR
- KEGG:   mmp:MMP0926
- NMPDR:   fig|267377.1.peg.926
- HOGENOM:   HBG705324
- OMA:   IGRDGAN
- ProtClustDB:   CLSK926279
- BioCyc:   MMAR267377:MMP0926-MONOMER
- BRENDA:   3.1.1.61
- GO:   GO:0005737
- GO:   GO:0006935
- HAMAP:   MF_00099
- InterPro:   IPR011006
- InterPro:   IPR008248
- InterPro:   IPR000673
- InterPro:   IPR001789
- Gene3D:   G3DSA:3.40.50.180
- PIRSF:   PIRSF000876
- SMART:   SM00448

Pfam domain/function: PF01339 CheB_methylest; PF00072 Response_reg; SSF52738 Chemotax_RR_pGlu_Me-esterase; SSF52172 CheY_like

EC number: =3.1.1.61

Molecular weight: Translated: 39792; Mature: 39661

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: PS50122 CHEB; PS50110 RESPONSE_REGULATORY

Important sites: ACT_SITE 182-182 ACT_SITE 208-208 ACT_SITE 305-305

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKIKVLIVDDSAFMRKVLEDILKSDDEIEVVATAKDGKEAFELVKKLEPNVITMDVEMP
CCCEEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCCEEEEEECCC
IMNGIDATKQIMAYKPTPILMLSAVTKQGSEATLKALDNGAVDFIEKPSGSVSLDIRKIG
CCCCCCHHHHHHEECCCCEEEEEHHHCCCCHHHHHHHCCCCEEEEECCCCCEEEHHHHHH
EKIIKQVKDASKSKVRIKSSRILENIKKEKQDESSTPKPQVEKTSGLSPEKLNDTAILIG
HHHHHHHHCCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCCCCEEEEE
SSTGGPPVVSSIISNIPKNTPPIFIVQHMPKGFTRVFAERMNNNSAITVKEAEHGEIVKP
CCCCCCHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCCCEECC
DHAYVAPGDSQMVLQKRGGNVYIIIDENMPKIHGTKPTVDVTAEYVTKYYGKNTIGVLLT
CCCEECCCCCEEEEEECCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEE
GIGRDGANGLKMVKNKGGYTIAQNQDTCVIYGMPKTAIEMNVVDKVMDPIDIPLEIIKFA
ECCCCCCCCHHHHHCCCCEEEECCCCEEEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHH
KKIGG
HHHCC
>Mature Secondary Structure 
SKIKVLIVDDSAFMRKVLEDILKSDDEIEVVATAKDGKEAFELVKKLEPNVITMDVEMP
CCEEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCCEEEEEECCC
IMNGIDATKQIMAYKPTPILMLSAVTKQGSEATLKALDNGAVDFIEKPSGSVSLDIRKIG
CCCCCCHHHHHHEECCCCEEEEEHHHCCCCHHHHHHHCCCCEEEEECCCCCEEEHHHHHH
EKIIKQVKDASKSKVRIKSSRILENIKKEKQDESSTPKPQVEKTSGLSPEKLNDTAILIG
HHHHHHHHCCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCCCCEEEEE
SSTGGPPVVSSIISNIPKNTPPIFIVQHMPKGFTRVFAERMNNNSAITVKEAEHGEIVKP
CCCCCCHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCCCEECC
DHAYVAPGDSQMVLQKRGGNVYIIIDENMPKIHGTKPTVDVTAEYVTKYYGKNTIGVLLT
CCCEECCCCCEEEEEECCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEE
GIGRDGANGLKMVKNKGGYTIAQNQDTCVIYGMPKTAIEMNVVDKVMDPIDIPLEIIKFA
ECCCCCCCCHHHHHCCCCEEEECCCCEEEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHH
KKIGG
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA