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The map label for this gene is cobY/cofC [H]

Identifier: 45358478

GI number: 45358478

Start: 904980

End: 905588

Strand: Direct

Name: cobY/cofC [H]

Synonym: MMP0915

Alternate gene names: 45358478

Gene position: 904980-905588 (Clockwise)

Preceding gene: 45358472

Following gene: 45358479

Centisome position: 54.48

GC content: 31.86

Gene sequence:

>609_bases
ATGGATGCACTAATCATGGCGGGCGGAAAAGGAACGCGGCTAAAAGAAAACGTGGAAAAACCAATTTTAAACATCTGCGA
AAAACCGATGATCGATTATGTTATCGACTCCCTTTTAAACTCCAAAATCGAAAAAATATATGTCGCAGTATCAATTCATA
CCCCTAAAACAAAAGAATATTTAGAAAAAAAATATCGTTTAGACCGAAATTATAATCCAAAGATAGATATAATTTGTACT
TCTGGAACAAATTATGTCGATGACCTAAATGAATGTATGGAATTTTTTAAAGAACCATTTTTAATTTTATCAAGCGACAT
CCCCACAATTAAGCCGAAAGTTATTAATAGTATAATACAGGATTATCTATTTGTTAACAATTCTTGTAATCGCATAGAGT
CCTTTTGTGTAGTCACAAAAGATGATGACTATGTTGGAACGCCCTCGATTAATATGGGTGGATACATACCTTTAGGTATC
AATATATTAACTCCAAAACATGGTGAACAGACCGAAATTCTCCATGTAATTAAAGATATTATTGTAAATGTCAATACTCT
CTCCGATAAAAAACTGGTTGAAACTTTAATTAATAAGGTGGTTGAATGA

Upstream 100 bases:

>100_bases
TAGAAACATATTCCATAATTATCCCCCGAATTGATAATGACACATTTAAATATGTTTTCAGGGTTATATAAATCATACTA
ATCATGTTAGCGTGAAAAAA

Downstream 100 bases:

>100_bases
AATTATCCTTTAAATCATTAAATGGTAGATCCATAGTTGGCAGTTTAGGTAGTATCATCGGCACCGTTGATGATATCGTA
ATTGATGAAAAAACAGGCAG

Product: nucleoside triphosphate: 5'-deoxyadenosylcobinamide phosphate nucleotidyltransferase

Products: NA

Alternate protein names: AdoCbi-P guanylyltransferase [H]

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MDALIMAGGKGTRLKENVEKPILNICEKPMIDYVIDSLLNSKIEKIYVAVSIHTPKTKEYLEKKYRLDRNYNPKIDIICT
SGTNYVDDLNECMEFFKEPFLILSSDIPTIKPKVINSIIQDYLFVNNSCNRIESFCVVTKDDDYVGTPSINMGGYIPLGI
NILTPKHGEQTEILHVIKDIIVNVNTLSDKKLVETLINKVVE

Sequences:

>Translated_202_residues
MDALIMAGGKGTRLKENVEKPILNICEKPMIDYVIDSLLNSKIEKIYVAVSIHTPKTKEYLEKKYRLDRNYNPKIDIICT
SGTNYVDDLNECMEFFKEPFLILSSDIPTIKPKVINSIIQDYLFVNNSCNRIESFCVVTKDDDYVGTPSINMGGYIPLGI
NILTPKHGEQTEILHVIKDIIVNVNTLSDKKLVETLINKVVE
>Mature_202_residues
MDALIMAGGKGTRLKENVEKPILNICEKPMIDYVIDSLLNSKIEKIYVAVSIHTPKTKEYLEKKYRLDRNYNPKIDIICT
SGTNYVDDLNECMEFFKEPFLILSSDIPTIKPKVINSIIQDYLFVNNSCNRIESFCVVTKDDDYVGTPSINMGGYIPLGI
NILTPKHGEQTEILHVIKDIIVNVNTLSDKKLVETLINKVVE

Specific function: Guanylyltransferase that catalyzes the synthesis of adenosylcobinamide-GDP (AdoCbi-GDP) from adenosylcobinamide- phosphate (AdoCbi-P) and GTP. Is involved in adenosylcobalamin biosynthesis. Binds one GTP per dimer. Can not use other NTPs or GDP. Does not

COG id: COG2266

COG function: function code H; GTP:adenosylcobinamide-phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005245
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.62 [H]

Molecular weight: Translated: 22929; Mature: 22929

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDALIMAGGKGTRLKENVEKPILNICEKPMIDYVIDSLLNSKIEKIYVAVSIHTPKTKEY
CCCEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEEEEEEEECCCCHHHH
LEKKYRLDRNYNPKIDIICTSGTNYVDDLNECMEFFKEPFLILSSDIPTIKPKVINSIIQ
HHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHH
DYLFVNNSCNRIESFCVVTKDDDYVGTPSINMGGYIPLGINILTPKHGEQTEILHVIKDI
HHHHHCCCCHHHHHEEEEECCCCCCCCCCCCCCCEEEECEEEECCCCCCHHHHHHHHHHH
IVNVNTLSDKKLVETLINKVVE
HHCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MDALIMAGGKGTRLKENVEKPILNICEKPMIDYVIDSLLNSKIEKIYVAVSIHTPKTKEY
CCCEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEEEEEEEECCCCHHHH
LEKKYRLDRNYNPKIDIICTSGTNYVDDLNECMEFFKEPFLILSSDIPTIKPKVINSIIQ
HHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHH
DYLFVNNSCNRIESFCVVTKDDDYVGTPSINMGGYIPLGINILTPKHGEQTEILHVIKDI
HHHHHCCCCHHHHHEEEEECCCCCCCCCCCCCCCEEEECEEEECCCCCCHHHHHHHHHHH
IVNVNTLSDKKLVETLINKVVE
HHCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]