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The map label for this gene is kamA [H]

Identifier: 45358424

GI number: 45358424

Start: 852237

End: 853538

Strand: Direct

Name: kamA [H]

Synonym: MMP0861

Alternate gene names: 45358424

Gene position: 852237-853538 (Clockwise)

Preceding gene: 45358423

Following gene: 45358425

Centisome position: 51.3

GC content: 34.41

Gene sequence:

>1302_bases
TTGAACGAATTAAGTGACGAAAGTATATTAAAATATACGAAAAAAATTTCAGAAAATGCCACAATTGATAATTGGAACGA
TTACAAGTGGCAGCTTTCAAATTCAATTAAAGATGTTGATACATTAGAAAATTTTTTAGGAATAACTTTTGATGAAAAAG
AGAAAACAGAAATCCAAAAAGCGATAGATGTATTTCCAATGTCAATTACTCCATACTATGCAAGTTTAATTGATATTAAA
AATTTAGGCAAAGACCCAATTTATAAACAAAGTGTGGCATCTTCAAAAGAACTCATACTTGAAAATTTTGAAATGGAAGA
TCCATTATCTGAAGATGAAGACTCCCCTGTTATTGGAATAACCCACCGGTATCCTGACAGAGTTTTATTTTACATAAACC
CAAACTGCGCAATGTACTGCAGGCACTGCACGAGAAAAAGAAAAGTTTCAGAAAAAAGCAGTAATCCGTCAAAAGAAGAG
ATTCAAAAGGCAATTGATTACATTAAAAATAACAATAAAATAAGAGACGTTCTACTTTCAGGAGGAGACCCGCTTTTACT
TTCCGATGAATTTTTAGACTGGATACTTTCAGAAATAAGCAGTATAAAACATGTTGAACTTATAAGAATCGGATCAAGAG
TTCCCGTGGTTCTTCCTCAAAGAATTACTGATAATTTAGTCAATGTTTTGAAAAAATACCATCCAATCTGGATAAATACT
CACTACAACCATCCAGTGGAGATTACTAAAGAATCTAAAAAAGCACTCGATAAACTTTCAGATTCTGGAATTCCCCTTGG
AAATCAGACGGTACTTTTAGCAGGAGTTAACGACTGTCCATATGTCATGAGAAAATTGAATCAAAAACTCGTTTCGTCAA
GAGTAAGGCCATACTACCTCTACCAGTGCGATTTATCAAAAGGAATTTCTCATTTTAGAACTTCTGTTAGCAAAGGACTT
GAAATTATCGAAAGTTTAATTGGACACACCACAGGTTTTGCAGTTCCTAGATACGTTGTAGATGCACCAGGAGGCGGTGG
AAAAATTCCAGTAATGCCAAATTACGTGGTTTCATGGGGTTCTGACCGAGTAATTTTAAGAAATTATGAAGGAATTATCA
CATCATACGTTGAACCGTCAGATTACGGTGGATGCAGTAAAAATTGCGATACGTGTGACAGAATGTGTATTGGGGACTTT
GAAATTAATCAAACGGGAATTGAAAAATTAATAACCGATGTAGACAATTCAATTTCATTAATCCCTGAAAACAACGAGCG
AGTTGCCAGGAGGGATGACTAA

Upstream 100 bases:

>100_bases
CGGTTTTTCGATTTGCTATTTGGGATACCCCCTCTGTTGATATATCAATGTTAAATTTCGAAAAATTTAGATATATCGAT
TATGTTTTTAGGTGATAGTT

Downstream 100 bases:

>100_bases
ATGGAAAAAATAATCGAAATAAATGATTCAATTATTCAAATAAGTGACTTAAATGATAGAATATATATAATGAAGCTTGG
AAAAGACGTAGGCGAATTAA

Product: lysine 2,3-aminomutase

Products: NA

Alternate protein names: LAM; KAM [H]

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MNELSDESILKYTKKISENATIDNWNDYKWQLSNSIKDVDTLENFLGITFDEKEKTEIQKAIDVFPMSITPYYASLIDIK
NLGKDPIYKQSVASSKELILENFEMEDPLSEDEDSPVIGITHRYPDRVLFYINPNCAMYCRHCTRKRKVSEKSSNPSKEE
IQKAIDYIKNNNKIRDVLLSGGDPLLLSDEFLDWILSEISSIKHVELIRIGSRVPVVLPQRITDNLVNVLKKYHPIWINT
HYNHPVEITKESKKALDKLSDSGIPLGNQTVLLAGVNDCPYVMRKLNQKLVSSRVRPYYLYQCDLSKGISHFRTSVSKGL
EIIESLIGHTTGFAVPRYVVDAPGGGGKIPVMPNYVVSWGSDRVILRNYEGIITSYVEPSDYGGCSKNCDTCDRMCIGDF
EINQTGIEKLITDVDNSISLIPENNERVARRDD

Sequences:

>Translated_433_residues
MNELSDESILKYTKKISENATIDNWNDYKWQLSNSIKDVDTLENFLGITFDEKEKTEIQKAIDVFPMSITPYYASLIDIK
NLGKDPIYKQSVASSKELILENFEMEDPLSEDEDSPVIGITHRYPDRVLFYINPNCAMYCRHCTRKRKVSEKSSNPSKEE
IQKAIDYIKNNNKIRDVLLSGGDPLLLSDEFLDWILSEISSIKHVELIRIGSRVPVVLPQRITDNLVNVLKKYHPIWINT
HYNHPVEITKESKKALDKLSDSGIPLGNQTVLLAGVNDCPYVMRKLNQKLVSSRVRPYYLYQCDLSKGISHFRTSVSKGL
EIIESLIGHTTGFAVPRYVVDAPGGGGKIPVMPNYVVSWGSDRVILRNYEGIITSYVEPSDYGGCSKNCDTCDRMCIGDF
EINQTGIEKLITDVDNSISLIPENNERVARRDD
>Mature_433_residues
MNELSDESILKYTKKISENATIDNWNDYKWQLSNSIKDVDTLENFLGITFDEKEKTEIQKAIDVFPMSITPYYASLIDIK
NLGKDPIYKQSVASSKELILENFEMEDPLSEDEDSPVIGITHRYPDRVLFYINPNCAMYCRHCTRKRKVSEKSSNPSKEE
IQKAIDYIKNNNKIRDVLLSGGDPLLLSDEFLDWILSEISSIKHVELIRIGSRVPVVLPQRITDNLVNVLKKYHPIWINT
HYNHPVEITKESKKALDKLSDSGIPLGNQTVLLAGVNDCPYVMRKLNQKLVSSRVRPYYLYQCDLSKGISHFRTSVSKGL
EIIESLIGHTTGFAVPRYVVDAPGGGGKIPVMPNYVVSWGSDRVILRNYEGIITSYVEPSDYGGCSKNCDTCDRMCIGDF
EINQTGIEKLITDVDNSISLIPENNERVARRDD

Specific function: Catalyzes the interconversion of L-alpha-lysine and L- beta-lysine [H]

COG id: COG1509

COG function: function code E; Lysine 2,3-aminomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the KamA family [H]

Homologues:

Organism=Escherichia coli, GI1790589, Length=328, Percent_Identity=32.3170731707317, Blast_Score=179, Evalue=3e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003739
- InterPro:   IPR022459
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: =5.4.3.2 [H]

Molecular weight: Translated: 49187; Mature: 49187

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNELSDESILKYTKKISENATIDNWNDYKWQLSNSIKDVDTLENFLGITFDEKEKTEIQK
CCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHH
AIDVFPMSITPYYASLIDIKNLGKDPIYKQSVASSKELILENFEMEDPLSEDEDSPVIGI
HHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHCHHHHHHHCCCCCCCCCCCCCCCEEEE
THRYPDRVLFYINPNCAMYCRHCTRKRKVSEKSSNPSKEEIQKAIDYIKNNNKIRDVLLS
EECCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEHEEC
GGDPLLLSDEFLDWILSEISSIKHVELIRIGSRVPVVLPQRITDNLVNVLKKYHPIWINT
CCCCEEECHHHHHHHHHHHHHCCCEEEEEECCCCCEECCHHHHHHHHHHHHHCCCEEEEC
HYNHPVEITKESKKALDKLSDSGIPLGNQTVLLAGVNDCPYVMRKLNQKLVSSRVRPYYL
CCCCCEEECHHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCEEEE
YQCDLSKGISHFRTSVSKGLEIIESLIGHTTGFAVPRYVVDAPGGGGKIPVMPNYVVSWG
EEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCHHEECC
SDRVILRNYEGIITSYVEPSDYGGCSKNCDTCDRMCIGDFEINQTGIEKLITDVDNSISL
CCEEEEECCCCHHEECCCCCCCCCCCCCCCHHHCEECCCCCCCHHHHHHHHHHCCCCEEE
IPENNERVARRDD
ECCCCCCCCCCCC
>Mature Secondary Structure
MNELSDESILKYTKKISENATIDNWNDYKWQLSNSIKDVDTLENFLGITFDEKEKTEIQK
CCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHH
AIDVFPMSITPYYASLIDIKNLGKDPIYKQSVASSKELILENFEMEDPLSEDEDSPVIGI
HHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHCHHHHHHHCCCCCCCCCCCCCCCEEEE
THRYPDRVLFYINPNCAMYCRHCTRKRKVSEKSSNPSKEEIQKAIDYIKNNNKIRDVLLS
EECCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEHEEC
GGDPLLLSDEFLDWILSEISSIKHVELIRIGSRVPVVLPQRITDNLVNVLKKYHPIWINT
CCCCEEECHHHHHHHHHHHHHCCCEEEEEECCCCCEECCHHHHHHHHHHHHHCCCEEEEC
HYNHPVEITKESKKALDKLSDSGIPLGNQTVLLAGVNDCPYVMRKLNQKLVSSRVRPYYL
CCCCCEEECHHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCEEEE
YQCDLSKGISHFRTSVSKGLEIIESLIGHTTGFAVPRYVVDAPGGGGKIPVMPNYVVSWG
EEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCHHEECC
SDRVILRNYEGIITSYVEPSDYGGCSKNCDTCDRMCIGDFEINQTGIEKLITDVDNSISL
CCEEEEECCCCHHEECCCCCCCCCCCCCCCHHHCEECCCCCCCHHHHHHHHHHCCCCEEE
IPENNERVARRDD
ECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10629195 [H]