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The map label for this gene is tlpC [H]

Identifier: 45358351

GI number: 45358351

Start: 778818

End: 780980

Strand: Direct

Name: tlpC [H]

Synonym: MMP0788

Alternate gene names: 45358351

Gene position: 778818-780980 (Clockwise)

Preceding gene: 45358349

Following gene: 45358353

Centisome position: 46.88

GC content: 34.21

Gene sequence:

>2163_bases
ATGCTTATTTTCTCCATTATAAGTGTTTTAGTACCCATACTTGTATTTGGTTTCGTTGCAAACGATACAATTGCAGGTAT
TTTGGATGATAATGCTCAAAAAAGTATTAATACTGATATAAAAATTGCAGATCAGATTATAGAATCAAGATTCATAGAAT
TTGAATCTATTTGCGAATATGCCACAAATAAAGCAGATGTTATAACCTCAGTATCTAATAAAGATTCTGAAAAATTAAGT
ATTGGTGTTGAAACATTTAGGGCGGCAATTAATTCAGATTTTGTTGGTGTTTTAGATTCAAATGGAAATACTATCGCATC
TACTGCAGGGCCAGATATTCAGATTGGAAGTGTGGCACAGAAACTGATAACTTCGGGAACTAAAAGATCTTTTGAACCAA
TTTCTGCAAACACTGCATACAAAATAAACAAAAATTACAAAGTAGAAAATGTAGATAGTGCCCTTGGAATGGTTGTTACA
TACCCGATTTATGAAAACGGCAATGTGGTAGGGTCCATTATAATAATTGATATTTTAAACAATAATAATGAAATAGTAGA
TCAGGTAAAAGCCGATACAGGCGATGAAGCCACGTTTTCTCTTGGAAAACAGAGAATCAGTACGAGTTTAATCGAGAATG
GAAAAAGACCTGTTGGAACTTCGATTTCTGATGAAGTTTGGACTTATGTAATGTCTCAAAATGCAGTATACAAAGGAACT
GCAAACGTTTTGGGAACTGAACTTATTACTGCTTATGCACCACTACTCGATGCAAATGATGATGTAATTGGAATGGTATT
TGTCGGGGCTCCGCAAACTGATGCAATTGCTGCTAAAAATGATGCACGAAACAAAATTATAATGCTTGCGTTATTTGGTA
TTTTGATTGCATTTTTGATTACATCATATTCAAACAGAAAAATTACAAAACCAATCGAAGAACTAAAAAAAGGAACTGAA
GAATTTGGAAATGGAAACTACGACTACAAAACAACGGTCAAAACTGGCGATGAATTACAAGAACTTTCAGATTCATTCAA
TAAAATGGCTGAAAATGTTAAGAATTTAATGAAAACAATGGATATGGACAAGTTAGAACTTGCAAATCTTCTTAATAATG
TATCTGATGTAATGAACAGGGTTGCAAAAGGAGATTTTACAGCAAGAGCTGATGAATCCCGTGAAAACAATAAACTTGAA
AAAGCAATTAACACTGCAGTTTCAAATGTTGCAGATTTGATTAAAGAATTACGCGAAGAATTGGATTTACTTAATATTCA
AATTCAAAAAGTTGAAGATGAATTAAAAGGAGCAGAAGAAACAGCCACCCAAGTTGCAGAGGCAGCAACTCAGGTTGCAG
AGGCAGCAAGTGATCAGTCTGCAAAACTACAGGAATCCTCTGAAGAACTTGAAAGTACGTATGAAAATGCAAAAGAAGTT
TACAGTGCAGCAGAAGAGACTGTTAAATCATCTGAAGAAATCAAAGAAAACTCTGAAATCGGGGTTGAAAAGGTTGAAAA
CGCAATTTCAAGAATGCAATCGATAACAAATGTAATCGATGAGCTTGGAAAATCAATCAAAATGCTTGGGGAAGATGGTA
AAAAAATTAATGAAGTTACGGGATTAATTAAAGATATTGCTGAACAAACTGGACTTTTGGCACTTAATGCTTCAATTGAA
GCTGCTCGTGCAGGGGACGCGGGAAAAGGATTTGCAGTTGTTGCAAGCGAAATTAAAGCACTGGCTGAAGAAATTAAAAA
GTCAGTTGAGGACATAAACCACACGATTGATGGGGTAAATAGTAGGATCGAAGATACTGTAGATCTTGGATTAAAAGGAA
AAGATGAGGTAGACAAAGGGGTAATCGCAATTGATGAGGTAAATGACGCACTTTTAAAAATTAAAGAAAGTGTAAATGAA
TCAGCAATAAAAATAAACGGAATTAAACATGGTGCACAAAACGCTTCTGAAAATACCGAAGGAGCTTTGAAAAATGCACA
AGATATTGCTGCACTATCAGAAGAATTCACTGCAACAGCAGAAGAAGTAACTGCTTCAACTGAGGAATTAAACTCAATTA
TCGAAGAAATTAGGGTTATTGCAGAAGAATTAACTCATGTATCTGAAAGAGTAAGTGAAAAATCGAATCAATTCGAAATT
TAA

Upstream 100 bases:

>100_bases
AGAAGATTAGTTAATGGATAATTAACTAAATTTCATGTCCAACGATAATAAGGGGTTGAATAAAATGAAATTAATAAATA
CTAAGAAATTGGGGACTAAA

Downstream 100 bases:

>100_bases
TTTCATTTATATTCTCTATTTAATTCTATTTTTTGATATATTGTGATAACTAATATTCCATTTTTAATATATGATTATAT
ATTTCATTAAACTCCAAAAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 720; Mature: 720

Protein sequence:

>720_residues
MLIFSIISVLVPILVFGFVANDTIAGILDDNAQKSINTDIKIADQIIESRFIEFESICEYATNKADVITSVSNKDSEKLS
IGVETFRAAINSDFVGVLDSNGNTIASTAGPDIQIGSVAQKLITSGTKRSFEPISANTAYKINKNYKVENVDSALGMVVT
YPIYENGNVVGSIIIIDILNNNNEIVDQVKADTGDEATFSLGKQRISTSLIENGKRPVGTSISDEVWTYVMSQNAVYKGT
ANVLGTELITAYAPLLDANDDVIGMVFVGAPQTDAIAAKNDARNKIIMLALFGILIAFLITSYSNRKITKPIEELKKGTE
EFGNGNYDYKTTVKTGDELQELSDSFNKMAENVKNLMKTMDMDKLELANLLNNVSDVMNRVAKGDFTARADESRENNKLE
KAINTAVSNVADLIKELREELDLLNIQIQKVEDELKGAEETATQVAEAATQVAEAASDQSAKLQESSEELESTYENAKEV
YSAAEETVKSSEEIKENSEIGVEKVENAISRMQSITNVIDELGKSIKMLGEDGKKINEVTGLIKDIAEQTGLLALNASIE
AARAGDAGKGFAVVASEIKALAEEIKKSVEDINHTIDGVNSRIEDTVDLGLKGKDEVDKGVIAIDEVNDALLKIKESVNE
SAIKINGIKHGAQNASENTEGALKNAQDIAALSEEFTATAEEVTASTEELNSIIEEIRVIAEELTHVSERVSEKSNQFEI

Sequences:

>Translated_720_residues
MLIFSIISVLVPILVFGFVANDTIAGILDDNAQKSINTDIKIADQIIESRFIEFESICEYATNKADVITSVSNKDSEKLS
IGVETFRAAINSDFVGVLDSNGNTIASTAGPDIQIGSVAQKLITSGTKRSFEPISANTAYKINKNYKVENVDSALGMVVT
YPIYENGNVVGSIIIIDILNNNNEIVDQVKADTGDEATFSLGKQRISTSLIENGKRPVGTSISDEVWTYVMSQNAVYKGT
ANVLGTELITAYAPLLDANDDVIGMVFVGAPQTDAIAAKNDARNKIIMLALFGILIAFLITSYSNRKITKPIEELKKGTE
EFGNGNYDYKTTVKTGDELQELSDSFNKMAENVKNLMKTMDMDKLELANLLNNVSDVMNRVAKGDFTARADESRENNKLE
KAINTAVSNVADLIKELREELDLLNIQIQKVEDELKGAEETATQVAEAATQVAEAASDQSAKLQESSEELESTYENAKEV
YSAAEETVKSSEEIKENSEIGVEKVENAISRMQSITNVIDELGKSIKMLGEDGKKINEVTGLIKDIAEQTGLLALNASIE
AARAGDAGKGFAVVASEIKALAEEIKKSVEDINHTIDGVNSRIEDTVDLGLKGKDEVDKGVIAIDEVNDALLKIKESVNE
SAIKINGIKHGAQNASENTEGALKNAQDIAALSEEFTATAEEVTASTEELNSIIEEIRVIAEELTHVSERVSEKSNQFEI
>Mature_720_residues
MLIFSIISVLVPILVFGFVANDTIAGILDDNAQKSINTDIKIADQIIESRFIEFESICEYATNKADVITSVSNKDSEKLS
IGVETFRAAINSDFVGVLDSNGNTIASTAGPDIQIGSVAQKLITSGTKRSFEPISANTAYKINKNYKVENVDSALGMVVT
YPIYENGNVVGSIIIIDILNNNNEIVDQVKADTGDEATFSLGKQRISTSLIENGKRPVGTSISDEVWTYVMSQNAVYKGT
ANVLGTELITAYAPLLDANDDVIGMVFVGAPQTDAIAAKNDARNKIIMLALFGILIAFLITSYSNRKITKPIEELKKGTE
EFGNGNYDYKTTVKTGDELQELSDSFNKMAENVKNLMKTMDMDKLELANLLNNVSDVMNRVAKGDFTARADESRENNKLE
KAINTAVSNVADLIKELREELDLLNIQIQKVEDELKGAEETATQVAEAATQVAEAASDQSAKLQESSEELESTYENAKEV
YSAAEETVKSSEEIKENSEIGVEKVENAISRMQSITNVIDELGKSIKMLGEDGKKINEVTGLIKDIAEQTGLLALNASIE
AARAGDAGKGFAVVASEIKALAEEIKKSVEDINHTIDGVNSRIEDTVDLGLKGKDEVDKGVIAIDEVNDALLKIKESVNE
SAIKINGIKHGAQNASENTEGALKNAQDIAALSEEFTATAEEVTASTEELNSIIEEIRVIAEELTHVSERVSEKSNQFEI

Specific function: Mediates Taxis To The Sugars Ribose And Galactose VIa An Interaction With The Periplasmic Ribose- Or Galactose-Binding Proteins. Chemotactic-Signal Transducers Respond To Changes In The Concentration Of Attractants And Repellents In The Environment, Trans

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=272, Percent_Identity=28.6764705882353, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1788195, Length=175, Percent_Identity=31.4285714285714, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1789453, Length=147, Percent_Identity=32.6530612244898, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI2367378, Length=278, Percent_Identity=27.3381294964029, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1788194, Length=282, Percent_Identity=25.531914893617, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 77959; Mature: 77959

Theoretical pI: Translated: 4.21; Mature: 4.21

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIFSIISVLVPILVFGFVANDTIAGILDDNAQKSINTDIKIADQIIESRFIEFESICEY
CHHHHHHHHHHHHHHHHHHHCCHHEEHCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHH
ATNKADVITSVSNKDSEKLSIGVETFRAAINSDFVGVLDSNGNTIASTAGPDIQIGSVAQ
HCCCHHHHEECCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCEEEECCCCCCCHHHHHH
KLITSGTKRSFEPISANTAYKINKNYKVENVDSALGMVVTYPIYENGNVVGSIIIIDILN
HHHHCCCCCCCCCCCCCCEEEECCCCCCCCHHHHHCEEEEEEEECCCCEEEEEEEEEEEC
NNNEIVDQVKADTGDEATFSLGKQRISTSLIENGKRPVGTSISDEVWTYVMSQNAVYKGT
CCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCEECCH
ANVLGTELITAYAPLLDANDDVIGMVFVGAPQTDAIAAKNDARNKIIMLALFGILIAFLI
HHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCEECCCCCCCHHHHHHHHHHHHHHHH
TSYSNRKITKPIEELKKGTEEFGNGNYDYKTTVKTGDELQELSDSFNKMAENVKNLMKTM
HCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHC
DMDKLELANLLNNVSDVMNRVAKGDFTARADESRENNKLEKAINTAVSNVADLIKELREE
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDLLNIQIQKVEDELKGAEETATQVAEAATQVAEAASDQSAKLQESSEELESTYENAKEV
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
YSAAEETVKSSEEIKENSEIGVEKVENAISRMQSITNVIDELGKSIKMLGEDGKKINEVT
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
GLIKDIAEQTGLLALNASIEAARAGDAGKGFAVVASEIKALAEEIKKSVEDINHTIDGVN
HHHHHHHHHCCEEEEECCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRIEDTVDLGLKGKDEVDKGVIAIDEVNDALLKIKESVNESAIKINGIKHGAQNASENTE
HHHHHHHHCCCCCCCCCCCCEEEEEHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCH
GALKNAQDIAALSEEFTATAEEVTASTEELNSIIEEIRVIAEELTHVSERVSEKSNQFEI
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLIFSIISVLVPILVFGFVANDTIAGILDDNAQKSINTDIKIADQIIESRFIEFESICEY
CHHHHHHHHHHHHHHHHHHHCCHHEEHCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHH
ATNKADVITSVSNKDSEKLSIGVETFRAAINSDFVGVLDSNGNTIASTAGPDIQIGSVAQ
HCCCHHHHEECCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCEEEECCCCCCCHHHHHH
KLITSGTKRSFEPISANTAYKINKNYKVENVDSALGMVVTYPIYENGNVVGSIIIIDILN
HHHHCCCCCCCCCCCCCCEEEECCCCCCCCHHHHHCEEEEEEEECCCCEEEEEEEEEEEC
NNNEIVDQVKADTGDEATFSLGKQRISTSLIENGKRPVGTSISDEVWTYVMSQNAVYKGT
CCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCEECCH
ANVLGTELITAYAPLLDANDDVIGMVFVGAPQTDAIAAKNDARNKIIMLALFGILIAFLI
HHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCEECCCCCCCHHHHHHHHHHHHHHHH
TSYSNRKITKPIEELKKGTEEFGNGNYDYKTTVKTGDELQELSDSFNKMAENVKNLMKTM
HCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHC
DMDKLELANLLNNVSDVMNRVAKGDFTARADESRENNKLEKAINTAVSNVADLIKELREE
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDLLNIQIQKVEDELKGAEETATQVAEAATQVAEAASDQSAKLQESSEELESTYENAKEV
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
YSAAEETVKSSEEIKENSEIGVEKVENAISRMQSITNVIDELGKSIKMLGEDGKKINEVT
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
GLIKDIAEQTGLLALNASIEAARAGDAGKGFAVVASEIKALAEEIKKSVEDINHTIDGVN
HHHHHHHHHCCEEEEECCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRIEDTVDLGLKGKDEVDKGVIAIDEVNDALLKIKESVNESAIKINGIKHGAQNASENTE
HHHHHHHHCCCCCCCCCCCCEEEEEHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCH
GALKNAQDIAALSEEFTATAEEVTASTEELNSIIEEIRVIAEELTHVSERVSEKSNQFEI
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7921238; 7704255; 8969502; 9384377 [H]