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The map label for this gene is paaK [H]

Identifier: 45358278

GI number: 45358278

Start: 708565

End: 709863

Strand: Direct

Name: paaK [H]

Synonym: MMP0715

Alternate gene names: 45358278

Gene position: 708565-709863 (Clockwise)

Preceding gene: 45358277

Following gene: 45358279

Centisome position: 42.66

GC content: 35.64

Gene sequence:

>1299_bases
ATGATTTGGAATGAAACTATTGAATGCATGGATCGAGAAGAGATGAGAGAACTTCAAAGTAAAAGGCTTTCTGATACAGT
TAGTCGTGTTTACCACAACGTTCCATTTTACCGGAAAAAAATGCAAAGTATGGGAGTTTATCCAGAAGATATTGAAAGTA
TTGACGACATTTCAAAACTTCCTTTTACAACAAAACAAGATTTAAGAGACAATTATCCTTTTGGAATATTTTCAGTTCCT
ATGGGCGAAATTGTAAGGGTTCACGCATCTTCCGGAACGACTGGAAAGCCAACAGTTGTAGGATACACGAGAAGAGATAT
TGCAATGTGGTCTGAAATAGTTGCAAGAGCATTAAGCTGTGCAGGAGCTTCAAGAGATGATTTCATCCAGATTGCTTATG
GATACGGCCTTTTTACGGGCGGTCTTGGATTGCATTATGGTGGTGAAAAATTAGGTGCAACAGTAATTCCAATTTCCGGT
GGAAATACTCAAAAACAGATTCAGTTAATGGCTGATTTTAAAACAACTGTTCTTGCATGCACGCCTTCATATGCTCTTTA
TTTAGCAGAAACACTGGAAGATTCAGGAATGACTGCTGATGACATTAATTTAAGAGTTGGAATTTTTGGTGCAGAACCAT
GGACTCCAAGCATGAGAAAAGAAATTGAAAATAAGCTTGGAATAAAAGCAATGGATATATACGGGCTTAGTGAAGTAATG
GGTCCAGGTGTAGCGTGCGACTGTGAATATCAGGAAGGATTACACATAAATGAAGACCATTTCGTTCCAGAAATTATTGA
TCCAGTTACATTAAAACCGCTTCCTGCAGGAAGTGAAGGGGAACTTGTATTTACAACAATTACTAAAGAAGGAATGCCTC
TTTTAAGGTACAGAACAAGAGATTTAACCTCATTAAATTACGAAAAATGTAAATGCGGAAGAACTCTTGTTAGGATGAAC
AAATGCACTGGAAGAAGCGACGACATGTTAATTATAAGGGGAGTTAACGTATTCCCATCACAAATAGAAAGTGTTCTTTT
AGAAATGAGCGAAACAAAGCCTCACTATTTATTAATAGTAGATAGGATAAATAATTTAGATGTTCTTGAAGTTTGGGTTG
AAATTGAAGACCAGTTCTTCTCAGACAAAATCAGTATGTTTGAACAGTTAAGTAAAAAAATCAAGCATAAAATCGAAAGT
ACTCTTGGAATAAGTGTTAAAATTAAACTTGTAGAGCCAAAAACTATTGAAAGAAGCGAAGGAAAATCCAAAAGGGTAAT
TGATAAAAGAAAACTATAA

Upstream 100 bases:

>100_bases
GAATGGATAAAAGCTATAAAAGACACAGTTCCTGAAAAATTTCTGGAATTGAACTTGAAAGCTTTTGAGATGGGTTACGA
TTTAAACTAGAAGGGATATC

Downstream 100 bases:

>100_bases
TGGAGGGGCCAATATGATTATCAAACAATTATCAGTATTTTTAGAAAATAAATCCGGAAGACTAAATGAGGTAACTGAAA
TACTCGAAAAAGCAGGAATA

Product: coenzyme F390 synthetase II

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MIWNETIECMDREEMRELQSKRLSDTVSRVYHNVPFYRKKMQSMGVYPEDIESIDDISKLPFTTKQDLRDNYPFGIFSVP
MGEIVRVHASSGTTGKPTVVGYTRRDIAMWSEIVARALSCAGASRDDFIQIAYGYGLFTGGLGLHYGGEKLGATVIPISG
GNTQKQIQLMADFKTTVLACTPSYALYLAETLEDSGMTADDINLRVGIFGAEPWTPSMRKEIENKLGIKAMDIYGLSEVM
GPGVACDCEYQEGLHINEDHFVPEIIDPVTLKPLPAGSEGELVFTTITKEGMPLLRYRTRDLTSLNYEKCKCGRTLVRMN
KCTGRSDDMLIIRGVNVFPSQIESVLLEMSETKPHYLLIVDRINNLDVLEVWVEIEDQFFSDKISMFEQLSKKIKHKIES
TLGISVKIKLVEPKTIERSEGKSKRVIDKRKL

Sequences:

>Translated_432_residues
MIWNETIECMDREEMRELQSKRLSDTVSRVYHNVPFYRKKMQSMGVYPEDIESIDDISKLPFTTKQDLRDNYPFGIFSVP
MGEIVRVHASSGTTGKPTVVGYTRRDIAMWSEIVARALSCAGASRDDFIQIAYGYGLFTGGLGLHYGGEKLGATVIPISG
GNTQKQIQLMADFKTTVLACTPSYALYLAETLEDSGMTADDINLRVGIFGAEPWTPSMRKEIENKLGIKAMDIYGLSEVM
GPGVACDCEYQEGLHINEDHFVPEIIDPVTLKPLPAGSEGELVFTTITKEGMPLLRYRTRDLTSLNYEKCKCGRTLVRMN
KCTGRSDDMLIIRGVNVFPSQIESVLLEMSETKPHYLLIVDRINNLDVLEVWVEIEDQFFSDKISMFEQLSKKIKHKIES
TLGISVKIKLVEPKTIERSEGKSKRVIDKRKL
>Mature_432_residues
MIWNETIECMDREEMRELQSKRLSDTVSRVYHNVPFYRKKMQSMGVYPEDIESIDDISKLPFTTKQDLRDNYPFGIFSVP
MGEIVRVHASSGTTGKPTVVGYTRRDIAMWSEIVARALSCAGASRDDFIQIAYGYGLFTGGLGLHYGGEKLGATVIPISG
GNTQKQIQLMADFKTTVLACTPSYALYLAETLEDSGMTADDINLRVGIFGAEPWTPSMRKEIENKLGIKAMDIYGLSEVM
GPGVACDCEYQEGLHINEDHFVPEIIDPVTLKPLPAGSEGELVFTTITKEGMPLLRYRTRDLTSLNYEKCKCGRTLVRMN
KCTGRSDDMLIIRGVNVFPSQIESVLLEMSETKPHYLLIVDRINNLDVLEVWVEIEDQFFSDKISMFEQLSKKIKHKIES
TLGISVKIKLVEPKTIERSEGKSKRVIDKRKL

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=437, Percent_Identity=54.4622425629291, Blast_Score=469, Evalue=1e-133,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 48686; Mature: 48686

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIWNETIECMDREEMRELQSKRLSDTVSRVYHNVPFYRKKMQSMGVYPEDIESIDDISKL
CCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHC
PFTTKQDLRDNYPFGIFSVPMGEIVRVHASSGTTGKPTVVGYTRRDIAMWSEIVARALSC
CCCCHHHHCCCCCCEEEECCCCCEEEEEECCCCCCCCEEEEECHHHHHHHHHHHHHHHHH
AGASRDDFIQIAYGYGLFTGGLGLHYGGEKLGATVIPISGGNTQKQIQLMADFKTTVLAC
CCCCCCCEEEEEECCEEEECCCEEEECCHHHCCEEEEECCCCCHHHEEEEECCCEEEEEE
TPSYALYLAETLEDSGMTADDINLRVGIFGAEPWTPSMRKEIENKLGIKAMDIYGLSEVM
CCCHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHCCCEEEEECCHHHHH
GPGVACDCEYQEGLHINEDHFVPEIIDPVTLKPLPAGSEGELVFTTITKEGMPLLRYRTR
CCCEEEECCCCCCCCCCCCCCCHHHCCCCEECCCCCCCCCCEEEEEECCCCCCEEHCCCC
DLTSLNYEKCKCGRTLVRMNKCTGRSDDMLIIRGVNVFPSQIESVLLEMSETKPHYLLIV
CCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEE
DRINNLDVLEVWVEIEDQFFSDKISMFEQLSKKIKHKIESTLGISVKIKLVEPKTIERSE
ECCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCC
GKSKRVIDKRKL
CCCHHCHHHCCC
>Mature Secondary Structure
MIWNETIECMDREEMRELQSKRLSDTVSRVYHNVPFYRKKMQSMGVYPEDIESIDDISKL
CCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHC
PFTTKQDLRDNYPFGIFSVPMGEIVRVHASSGTTGKPTVVGYTRRDIAMWSEIVARALSC
CCCCHHHHCCCCCCEEEECCCCCEEEEEECCCCCCCCEEEEECHHHHHHHHHHHHHHHHH
AGASRDDFIQIAYGYGLFTGGLGLHYGGEKLGATVIPISGGNTQKQIQLMADFKTTVLAC
CCCCCCCEEEEEECCEEEECCCEEEECCHHHCCEEEEECCCCCHHHEEEEECCCEEEEEE
TPSYALYLAETLEDSGMTADDINLRVGIFGAEPWTPSMRKEIENKLGIKAMDIYGLSEVM
CCCHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHCCCEEEEECCHHHHH
GPGVACDCEYQEGLHINEDHFVPEIIDPVTLKPLPAGSEGELVFTTITKEGMPLLRYRTR
CCCEEEECCCCCCCCCCCCCCCHHHCCCCEECCCCCCCCCCEEEEEECCCCCCEEHCCCC
DLTSLNYEKCKCGRTLVRMNKCTGRSDDMLIIRGVNVFPSQIESVLLEMSETKPHYLLIV
CCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEE
DRINNLDVLEVWVEIEDQFFSDKISMFEQLSKKIKHKIESTLGISVKIKLVEPKTIERSE
ECCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCC
GKSKRVIDKRKL
CCCHHCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]