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The map label for this gene is yicO [C]

Identifier: 45358252

GI number: 45358252

Start: 677464

End: 678765

Strand: Direct

Name: yicO [C]

Synonym: MMP0689

Alternate gene names: 45358252

Gene position: 677464-678765 (Clockwise)

Preceding gene: 45358250

Following gene: 45358260

Centisome position: 40.78

GC content: 38.94

Gene sequence:

>1302_bases
ATGGCAAATTTTTTGGCTAGGTACTTTGGGTTTGAAGAACATAAAACAAACTTCAAAGTAGAGACCATGGCAGGAGTTAC
GACTTTTATGACCATGGCGTATATCATATTTGTAAATCCGTCGATTCTAAGTCTGGCGGGAATGGACTTTGGGGCAGTAA
TGGTTGCAACATGTATATCTGCTGCACTCGGTACTTTTATAATGGGTGTTTATGCTAAATATCCGTTTGCACTTGCACCG
GGGATGGGTTTAAACGCATTCTTTACATTTGGTGTAGTTATGGGCATGGGCCTAAGCTGGCAGACTGCTCTTGGTGCTGT
TTTTATTTCTGGTATTTTATTCATTTTGTTAACATTAACTAAAATTAGAACATGGATATTTGATGCGATACCTGACGCTT
TGAAATACGGTACTGCTGTAGGTATCGGGTTATTTATTGCATTTATCGGTTTAAAATCTGCAGGAGTTATCGTTGCAAAC
GAAGCTACATTGGTAGGTCTTGGAAACGTTCTTTCACCTGCAACATTTTTGGCACTCTTTGGTTTATTTGCAACTGCTGC
AATGATGGCTAGAAAAGTAACAGGTGCAATTCTCTGGGGTATTATCTTAACCGCAGTAATTGGTATGGGCCTTGGTGTTT
CAGCACTTCCTGCAGGTTTAGTTGCAATGCCTCCATCCTTAGCACCAACACTGATGCAGATGGATGTTATGGGAGCTCTT
AGTTTTGGCCTCATAAACATAATTTTGGCGTTCTTCTTTGTGGATTTATTTGATACACTTGGAACCTTAAGTGCTCTAAG
TTCACAGGCAGGATACATGAAAGATGGAAAACTTCCAAAAGCAGAAAAAGCATTAATGTCTGATTCAGTTGCAACTGCGG
TTGGGGCAGCTTTAGGTACTTCAACAGTTACAAGCTACGTTGAATCTGCTTCAGGTATCGGACTTGGTGGAAGAACCGGA
TTTGTTTCAGTTGTAGTTGCCGCTTTATTTTTACTTTCGATATTCTTCTCACCATTTGTTGCGGCAATTCCGGCATATGC
TACTGCTCCTGCATTAATAATCGTTGGAGCTTTAATGATTTCAGCAATAAAAAGAATCGATTTAGATGACATTACTGAAT
CAGTTCCTGCATTTATTGCATTAATTACAATTCCTTTAACGTACAGTATTGCAACGGGACTTCAATTAGGGTTTATTTTC
TACCCGTTAATTAAAATAATTGCAGGACGTTCAAAAGAAGTACACCCAATCGTATATTTACTTGCAATCATCTTTGCAGC
AAGATTTGTATACATTGGATAA

Upstream 100 bases:

>100_bases
AAACATCATTATCACTAAATTTCTAAATTTTATGATGAAATGTAATCTTTATATTCATAATAGTTGCTTATATTATATAT
TAATTAACTGGGGTGAACTT

Downstream 100 bases:

>100_bases
CTAAAAATCTTAAATCTTTTTTTCTATTTTTTGATTATTTTAAAACTAAAAAAGTAAATTTAAAAATTATTTTCCATATT
TTATTCCACCTTTTTTACAA

Product: xanthine/uracil permease family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 432

Protein sequence:

>433_residues
MANFLARYFGFEEHKTNFKVETMAGVTTFMTMAYIIFVNPSILSLAGMDFGAVMVATCISAALGTFIMGVYAKYPFALAP
GMGLNAFFTFGVVMGMGLSWQTALGAVFISGILFILLTLTKIRTWIFDAIPDALKYGTAVGIGLFIAFIGLKSAGVIVAN
EATLVGLGNVLSPATFLALFGLFATAAMMARKVTGAILWGIILTAVIGMGLGVSALPAGLVAMPPSLAPTLMQMDVMGAL
SFGLINIILAFFFVDLFDTLGTLSALSSQAGYMKDGKLPKAEKALMSDSVATAVGAALGTSTVTSYVESASGIGLGGRTG
FVSVVVAALFLLSIFFSPFVAAIPAYATAPALIIVGALMISAIKRIDLDDITESVPAFIALITIPLTYSIATGLQLGFIF
YPLIKIIAGRSKEVHPIVYLLAIIFAARFVYIG

Sequences:

>Translated_433_residues
MANFLARYFGFEEHKTNFKVETMAGVTTFMTMAYIIFVNPSILSLAGMDFGAVMVATCISAALGTFIMGVYAKYPFALAP
GMGLNAFFTFGVVMGMGLSWQTALGAVFISGILFILLTLTKIRTWIFDAIPDALKYGTAVGIGLFIAFIGLKSAGVIVAN
EATLVGLGNVLSPATFLALFGLFATAAMMARKVTGAILWGIILTAVIGMGLGVSALPAGLVAMPPSLAPTLMQMDVMGAL
SFGLINIILAFFFVDLFDTLGTLSALSSQAGYMKDGKLPKAEKALMSDSVATAVGAALGTSTVTSYVESASGIGLGGRTG
FVSVVVAALFLLSIFFSPFVAAIPAYATAPALIIVGALMISAIKRIDLDDITESVPAFIALITIPLTYSIATGLQLGFIF
YPLIKIIAGRSKEVHPIVYLLAIIFAARFVYIG
>Mature_432_residues
ANFLARYFGFEEHKTNFKVETMAGVTTFMTMAYIIFVNPSILSLAGMDFGAVMVATCISAALGTFIMGVYAKYPFALAPG
MGLNAFFTFGVVMGMGLSWQTALGAVFISGILFILLTLTKIRTWIFDAIPDALKYGTAVGIGLFIAFIGLKSAGVIVANE
ATLVGLGNVLSPATFLALFGLFATAAMMARKVTGAILWGIILTAVIGMGLGVSALPAGLVAMPPSLAPTLMQMDVMGALS
FGLINIILAFFFVDLFDTLGTLSALSSQAGYMKDGKLPKAEKALMSDSVATAVGAALGTSTVTSYVESASGIGLGGRTGF
VSVVVAALFLLSIFFSPFVAAIPAYATAPALIIVGALMISAIKRIDLDDITESVPAFIALITIPLTYSIATGLQLGFIFY
PLIKIIAGRSKEVHPIVYLLAIIFAARFVYIG

Specific function: Unknown

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082309, Length=429, Percent_Identity=45.6876456876457, Blast_Score=374, Evalue=1e-105,
Organism=Escherichia coli, GI1790150, Length=429, Percent_Identity=46.3869463869464, Blast_Score=370, Evalue=1e-103,
Organism=Escherichia coli, GI1790499, Length=419, Percent_Identity=34.8448687350835, Blast_Score=239, Evalue=2e-64,
Organism=Escherichia coli, GI48994909, Length=418, Percent_Identity=36.1244019138756, Blast_Score=235, Evalue=3e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 45273; Mature: 45142

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANFLARYFGFEEHKTNFKVETMAGVTTFMTMAYIIFVNPSILSLAGMDFGAVMVATCIS
CHHHHHHHHCCHHHCCCCEEHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHH
AALGTFIMGVYAKYPFALAPGMGLNAFFTFGVVMGMGLSWQTALGAVFISGILFILLTLT
HHHHHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
KIRTWIFDAIPDALKYGTAVGIGLFIAFIGLKSAGVIVANEATLVGLGNVLSPATFLALF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEECCHHHHHHHHHHHH
GLFATAAMMARKVTGAILWGIILTAVIGMGLGVSALPAGLVAMPPSLAPTLMQMDVMGAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHCCCCHHHHHHHHHHHHHH
SFGLINIILAFFFVDLFDTLGTLSALSSQAGYMKDGKLPKAEKALMSDSVATAVGAALGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
STVTSYVESASGIGLGGRTGFVSVVVAALFLLSIFFSPFVAAIPAYATAPALIIVGALMI
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAIKRIDLDDITESVPAFIALITIPLTYSIATGLQLGFIFYPLIKIIAGRSKEVHPIVYL
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
LAIIFAARFVYIG
HHHHHHHHHHHCC
>Mature Secondary Structure 
ANFLARYFGFEEHKTNFKVETMAGVTTFMTMAYIIFVNPSILSLAGMDFGAVMVATCIS
HHHHHHHHCCHHHCCCCEEHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHH
AALGTFIMGVYAKYPFALAPGMGLNAFFTFGVVMGMGLSWQTALGAVFISGILFILLTLT
HHHHHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
KIRTWIFDAIPDALKYGTAVGIGLFIAFIGLKSAGVIVANEATLVGLGNVLSPATFLALF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEECCHHHHHHHHHHHH
GLFATAAMMARKVTGAILWGIILTAVIGMGLGVSALPAGLVAMPPSLAPTLMQMDVMGAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHCCCCHHHHHHHHHHHHHH
SFGLINIILAFFFVDLFDTLGTLSALSSQAGYMKDGKLPKAEKALMSDSVATAVGAALGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
STVTSYVESASGIGLGGRTGFVSVVVAALFLLSIFFSPFVAAIPAYATAPALIIVGALMI
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAIKRIDLDDITESVPAFIALITIPLTYSIATGLQLGFIFYPLIKIIAGRSKEVHPIVYL
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
LAIIFAARFVYIG
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]