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The map label for this gene is modD [H]

Identifier: 45358079

GI number: 45358079

Start: 521710

End: 522561

Strand: Direct

Name: modD [H]

Synonym: MMP0516

Alternate gene names: 45358079

Gene position: 521710-522561 (Clockwise)

Preceding gene: 45358078

Following gene: 45358089

Centisome position: 31.41

GC content: 34.51

Gene sequence:

>852_bases
ATGTCATTTTATATTCCTGATTATGAACTTGAAAAAATAATTGAAGAGGATATAAATCCCCTTGATTTAACCTCGCAGAT
AATGAAACTGGATCGATTTAATGCAAAACTTGCATACAAAGCACGACACGATATGGTTTTGTGCTGTACTGAAGAAGCTG
AGAGAATATGTAAAATACTCGGGCTGGAAGTAATTTCTTATAAACGCACTGGATCTTATGTAAAAGAAGGCGAAGTATTT
TTTGAAGCAAAAGGGAGGGCTGACAATGTTCACCTTGCATGGAAAAGCGTTTTAAGGCTTCTTGAAGGATACTGCGGGAT
GGCTACGAGAACTTACGAGTTTGTGACCTTAGCAAGAAAGTATAACGAAAACACAAATGTTGTAACCACTCGAAAAAATC
TTGCAGGAACTAAAAAACCGACAATAAAAGCAATAGTTGCAGGCGGAGCATATCCTCACAGACTCGGTCTTTCTGAAACT
ATATTGATATTTGATGAACATCTGGCTTTTGTTGATGGTGATGAAGAACTAAAATGTGTTTTAAAAGAAATGAAAGCAAA
TGCTTTAGAAAAAAAGATAGGAATAGAAGTAGATAATTTTGAAACGGGTATAAAATACGTTAAAATGGGTTTTGATTATA
TTCAGCTCGATAAAGTTGATTCCAAAACCGTTGAAAAGTTCGTAAAAGCCGCAAAAGAAATAAATCCAAACATTACGATA
GTTGCAGCAGGTGGAATTACCATTCAAAATATAGAAGAATATGCTAAAACCGGTGCTGAAGTTATTGTTACTTCCGCCCT
TTATTTTGGAAAAGCTGCGGATATAAAAACAATAATTGAAAAAATAGACTAA

Upstream 100 bases:

>100_bases
AAAAAGATTTTATATGCTGGTGAATTAAATGTTAAATCAAGTGATTTGGTGTTTGGTTTAAGTAATATTTAATTTAAAAA
AACCTAAAAAGAGGTTTAAT

Downstream 100 bases:

>100_bases
GTATAACGAATTAAACTAAATTATAATTTAATATTCATTTTTGTACAGAATCCCGTCGTGTCCTGTAACAATATTTTTAT
TAAGGCTTTTTATTTTTCTT

Product: quinolinate phosphoribosyl transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 283; Mature: 282

Protein sequence:

>283_residues
MSFYIPDYELEKIIEEDINPLDLTSQIMKLDRFNAKLAYKARHDMVLCCTEEAERICKILGLEVISYKRTGSYVKEGEVF
FEAKGRADNVHLAWKSVLRLLEGYCGMATRTYEFVTLARKYNENTNVVTTRKNLAGTKKPTIKAIVAGGAYPHRLGLSET
ILIFDEHLAFVDGDEELKCVLKEMKANALEKKIGIEVDNFETGIKYVKMGFDYIQLDKVDSKTVEKFVKAAKEINPNITI
VAAGGITIQNIEEYAKTGAEVIVTSALYFGKAADIKTIIEKID

Sequences:

>Translated_283_residues
MSFYIPDYELEKIIEEDINPLDLTSQIMKLDRFNAKLAYKARHDMVLCCTEEAERICKILGLEVISYKRTGSYVKEGEVF
FEAKGRADNVHLAWKSVLRLLEGYCGMATRTYEFVTLARKYNENTNVVTTRKNLAGTKKPTIKAIVAGGAYPHRLGLSET
ILIFDEHLAFVDGDEELKCVLKEMKANALEKKIGIEVDNFETGIKYVKMGFDYIQLDKVDSKTVEKFVKAAKEINPNITI
VAAGGITIQNIEEYAKTGAEVIVTSALYFGKAADIKTIIEKID
>Mature_282_residues
SFYIPDYELEKIIEEDINPLDLTSQIMKLDRFNAKLAYKARHDMVLCCTEEAERICKILGLEVISYKRTGSYVKEGEVFF
EAKGRADNVHLAWKSVLRLLEGYCGMATRTYEFVTLARKYNENTNVVTTRKNLAGTKKPTIKAIVAGGAYPHRLGLSETI
LIFDEHLAFVDGDEELKCVLKEMKANALEKKIGIEVDNFETGIKYVKMGFDYIQLDKVDSKTVEKFVKAAKEINPNITIV
AAGGITIQNIEEYAKTGAEVIVTSALYFGKAADIKTIIEKID

Specific function: NAD biosynthesis; aspartate to NaMN; third (last) step. [C]

COG id: COG0157

COG function: function code H; Nicotinate-nucleotide pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nadC/modD family [H]

Homologues:

Organism=Escherichia coli, GI1786299, Length=237, Percent_Identity=24.8945147679325, Blast_Score=64, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321162, Length=272, Percent_Identity=23.1617647058824, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006242
- InterPro:   IPR002638
- InterPro:   IPR022412 [H]

Pfam domain/function: PF01729 QRPTase_C; PF02749 QRPTase_N [H]

EC number: 2.4.2.-

Molecular weight: Translated: 31846; Mature: 31715

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFYIPDYELEKIIEEDINPLDLTSQIMKLDRFNAKLAYKARHDMVLCCTEEAERICKIL
CCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEECCCCEEEEECHHHHHHHHHH
GLEVISYKRTGSYVKEGEVFFEAKGRADNVHLAWKSVLRLLEGYCGMATRTYEFVTLARK
HHHHEEEECCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
YNENTNVVTTRKNLAGTKKPTIKAIVAGGAYPHRLGLSETILIFDEHLAFVDGDEELKCV
HCCCCCEEEECHHCCCCCCCCEEEEEECCCCCCCCCCCCEEEEEECCEEEECCCHHHHHH
LKEMKANALEKKIGIEVDNFETGIKYVKMGFDYIQLDKVDSKTVEKFVKAAKEINPNITI
HHHHHHHHHHHHHCCEECCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCEEE
VAAGGITIQNIEEYAKTGAEVIVTSALYFGKAADIKTIIEKID
EEECCEEHHHHHHHHHCCHHEEEHHHHHHCCCCHHHHHHHHCC
>Mature Secondary Structure 
SFYIPDYELEKIIEEDINPLDLTSQIMKLDRFNAKLAYKARHDMVLCCTEEAERICKIL
CCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEECCCCEEEEECHHHHHHHHHH
GLEVISYKRTGSYVKEGEVFFEAKGRADNVHLAWKSVLRLLEGYCGMATRTYEFVTLARK
HHHHEEEECCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
YNENTNVVTTRKNLAGTKKPTIKAIVAGGAYPHRLGLSETILIFDEHLAFVDGDEELKCV
HCCCCCEEEECHHCCCCCCCCEEEEEECCCCCCCCCCCCEEEEEECCEEEECCCHHHHHH
LKEMKANALEKKIGIEVDNFETGIKYVKMGFDYIQLDKVDSKTVEKFVKAAKEINPNITI
HHHHHHHHHHHHHCCEECCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCEEE
VAAGGITIQNIEEYAKTGAEVIVTSALYFGKAADIKTIIEKID
EEECCEEHHHHHHHHHCCHHEEEHHHHHHCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]