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The map label for this gene is fmdA [H]

Identifier: 45358072

GI number: 45358072

Start: 512896

End: 514647

Strand: Direct

Name: fmdA [H]

Synonym: MMP0509

Alternate gene names: 45358072

Gene position: 512896-514647 (Clockwise)

Preceding gene: 45358071

Following gene: 45358073

Centisome position: 30.88

GC content: 40.07

Gene sequence:

>1752_bases
ATGACCAAGATGGTTATAAAAGGCGGGACTGTTTATGACCCCCTAAATGGTATTGATGGAGAAGTAATGGATATCTTCAT
CAAGGATGGGAAAATTGTTGAAAACCTGTCCGATGGCGAATTAAAAGATGCTAAAATTTTAGATGTAAAAGGAAAAGTGG
TAATGCCTGGAGGAGTTGATTCCCACACTCACGTTGCAGGACCTAAAGTAAATACTGGAAGAGTAATGTGTCCAGAAGAC
CACTACAAATCCCCTTTGAAAAAAACCCACAACACACACTGCGGTTCTGGGGAAATTGTTCCTTCAACATATGCGCAAGG
ATACAAATACTCTTCAATGGGTTACACAACCTTATTTGAAGCAGCAGTACCTCCAATGCTTGCAAGACACACTCACGAAG
AGTTTAAAGTAATGCCAATCGTTGACAAAGCAGGATATCTTCTTTTGGGAAGCAACTGGTTTGTAATGAAATATTTAAAA
GAAGGAAATGTTGAAAAAGCGGCAGCATACGTTGCATGGGCTCTTGAAACAACAAAAACCTTTGGTATTAAACTCGTAAA
CCCTGCAGGTGTCGAAAGCTGGGCATGGGGTAAAAACGTACACTCACTCGAAGAAGAAAACATTCACTTCGGTATTTCTT
CAGGTGAAGTGATTAGAGGGCTTGGTGCAGTAAACGAAATGCTTGGCCTTCCAATGTCAATACACCTTCACGCAAACAAC
CTCGGTCACCCTGGAAACTGGGAGTTTACAATTGACACGATGGATGTTGCAAAAAATATCAAGCCTGCAGTTAACAAACA
AGGCTATGATAATGGCGTAAAGACAAAATACTCACACGAAAGGGAACAAAGCTTGTACATGACCCACATGCAATTCCACT
CATTTGGTGGAACGTCATGGAAAGACTTTGAATCTAAAGCTGAAGATATTTCAAACTATGTTAACAAATCTGACCACGTT
GTAATGGACAGTGGTAGCGTTGCATTTGGAAAGGCTATTTGTATGACTGGAGACGGTCCTGGTCTTTACGATCTGGCTGT
AATGAATGGTCAAAAATGGGCAAACGTGGATGTTGAACTCGAATGTGGTTCAGGTGTCGTTCCATTTGTATACAGTATGA
AAAACAAGGTACACAGCGTTCAATGGGCAATGGGTATCGAGCTTTTATTATTGACTGACCCTAGAAAAGTTATAATGACT
ACAGATAACCCTAACGCAGGACCTTTCACGAAATACCCTCAATTAATTACCTGGTTAATGTCTAAAAAGGCAAGAGAAGA
CACAATGAAACTATGCCACAAATGGGCCGGTGAAAGAAGTGGTCTTGCTGGAAATGATAAAGAACTCAGCCTTTACGACT
TAGCTACCGTTACAAGGGCAACCCCTGCTAAAGCAATTGGTATGGGACACAGGAAAGGACATTTAAGCCCTGGTGCTGAT
GCAGATATTACAGTTTATGATATAAGTCCTGATTACAACTCCAGTGACTATGCAGCAATCGAAAAAGCATTTACAACTGC
ACTATTCACAATAAAAGATGGAGAAGTAATTACCAAAGATGGACGAATTATCGAAACTCCAAAAGGTAGGACTTACTACG
TTGACGCTAAATTCAACGAAGAAATACAAAAAGAAATTATTGCAGATGTACAGGATTGGTTTAGAAGATATTACTCAATT
GGCTTCTCAAATTATCCAGTTCCTGATCTATACCTCACAAAACCAACTCCCCTTAATATCAATGTGAGATAG

Upstream 100 bases:

>100_bases
AAAGAACCATTCATACAACAAAATGGCGAAAAGAAATGTTTAGCTTGTTCTAAATAATCTTATCATTTTAGATTTGCTGA
ATTAATACACTGGTGGTATG

Downstream 100 bases:

>100_bases
GTGAGAATCATGGGAGAAATTATACTTAAACCAAAATATAATGGTACGATACCCGTAGAATGTGATGTAATTACACCAGA
CACATTTGAAGGAAAATCAA

Product: formylmethanofuran dehydrogenase subunit A

Products: CO2; methanofuran; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 583; Mature: 582

Protein sequence:

>583_residues
MTKMVIKGGTVYDPLNGIDGEVMDIFIKDGKIVENLSDGELKDAKILDVKGKVVMPGGVDSHTHVAGPKVNTGRVMCPED
HYKSPLKKTHNTHCGSGEIVPSTYAQGYKYSSMGYTTLFEAAVPPMLARHTHEEFKVMPIVDKAGYLLLGSNWFVMKYLK
EGNVEKAAAYVAWALETTKTFGIKLVNPAGVESWAWGKNVHSLEEENIHFGISSGEVIRGLGAVNEMLGLPMSIHLHANN
LGHPGNWEFTIDTMDVAKNIKPAVNKQGYDNGVKTKYSHEREQSLYMTHMQFHSFGGTSWKDFESKAEDISNYVNKSDHV
VMDSGSVAFGKAICMTGDGPGLYDLAVMNGQKWANVDVELECGSGVVPFVYSMKNKVHSVQWAMGIELLLLTDPRKVIMT
TDNPNAGPFTKYPQLITWLMSKKAREDTMKLCHKWAGERSGLAGNDKELSLYDLATVTRATPAKAIGMGHRKGHLSPGAD
ADITVYDISPDYNSSDYAAIEKAFTTALFTIKDGEVITKDGRIIETPKGRTYYVDAKFNEEIQKEIIADVQDWFRRYYSI
GFSNYPVPDLYLTKPTPLNINVR

Sequences:

>Translated_583_residues
MTKMVIKGGTVYDPLNGIDGEVMDIFIKDGKIVENLSDGELKDAKILDVKGKVVMPGGVDSHTHVAGPKVNTGRVMCPED
HYKSPLKKTHNTHCGSGEIVPSTYAQGYKYSSMGYTTLFEAAVPPMLARHTHEEFKVMPIVDKAGYLLLGSNWFVMKYLK
EGNVEKAAAYVAWALETTKTFGIKLVNPAGVESWAWGKNVHSLEEENIHFGISSGEVIRGLGAVNEMLGLPMSIHLHANN
LGHPGNWEFTIDTMDVAKNIKPAVNKQGYDNGVKTKYSHEREQSLYMTHMQFHSFGGTSWKDFESKAEDISNYVNKSDHV
VMDSGSVAFGKAICMTGDGPGLYDLAVMNGQKWANVDVELECGSGVVPFVYSMKNKVHSVQWAMGIELLLLTDPRKVIMT
TDNPNAGPFTKYPQLITWLMSKKAREDTMKLCHKWAGERSGLAGNDKELSLYDLATVTRATPAKAIGMGHRKGHLSPGAD
ADITVYDISPDYNSSDYAAIEKAFTTALFTIKDGEVITKDGRIIETPKGRTYYVDAKFNEEIQKEIIADVQDWFRRYYSI
GFSNYPVPDLYLTKPTPLNINVR
>Mature_582_residues
TKMVIKGGTVYDPLNGIDGEVMDIFIKDGKIVENLSDGELKDAKILDVKGKVVMPGGVDSHTHVAGPKVNTGRVMCPEDH
YKSPLKKTHNTHCGSGEIVPSTYAQGYKYSSMGYTTLFEAAVPPMLARHTHEEFKVMPIVDKAGYLLLGSNWFVMKYLKE
GNVEKAAAYVAWALETTKTFGIKLVNPAGVESWAWGKNVHSLEEENIHFGISSGEVIRGLGAVNEMLGLPMSIHLHANNL
GHPGNWEFTIDTMDVAKNIKPAVNKQGYDNGVKTKYSHEREQSLYMTHMQFHSFGGTSWKDFESKAEDISNYVNKSDHVV
MDSGSVAFGKAICMTGDGPGLYDLAVMNGQKWANVDVELECGSGVVPFVYSMKNKVHSVQWAMGIELLLLTDPRKVIMTT
DNPNAGPFTKYPQLITWLMSKKAREDTMKLCHKWAGERSGLAGNDKELSLYDLATVTRATPAKAIGMGHRKGHLSPGADA
DITVYDISPDYNSSDYAAIEKAFTTALFTIKDGEVITKDGRIIETPKGRTYYVDAKFNEEIQKEIIADVQDWFRRYYSIG
FSNYPVPDLYLTKPTPLNINVR

Specific function: Unknown

COG id: COG1229

COG function: function code C; Formylmethanofuran dehydrogenase subunit A

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013108
- InterPro:   IPR012027
- InterPro:   IPR011059 [H]

Pfam domain/function: PF07969 Amidohydro_3 [H]

EC number: 1.2.99.5

Molecular weight: Translated: 64595; Mature: 64464

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKMVIKGGTVYDPLNGIDGEVMDIFIKDGKIVENLSDGELKDAKILDVKGKVVMPGGVD
CCEEEEECCCEECCCCCCCCCEEEEEEECCCEECCCCCCCCCCCEEEEECCCEEECCCCC
SHTHVAGPKVNTGRVMCPEDHYKSPLKKTHNTHCGSGEIVPSTYAQGYKYSSMGYTTLFE
CCCCCCCCCCCCCEEECCHHHHCCHHHHHCCCCCCCCCCCCCHHHCCEEECCCCHHHHHH
AAVPPMLARHTHEEFKVMPIVDKAGYLLLGSNWFVMKYLKEGNVEKAAAYVAWALETTKT
HHCCHHHHHCCCCCEEEEEEECCCCEEEECCCEEEEEEECCCCHHHHHEEEEEEEECCCC
FGIKLVNPAGVESWAWGKNVHSLEEENIHFGISSGEVIRGLGAVNEMLGLPMSIHLHANN
CCEEEECCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCEEEEEEECC
LGHPGNWEFTIDTMDVAKNIKPAVNKQGYDNGVKTKYSHEREQSLYMTHMQFHSFGGTSW
CCCCCCEEEEEEHHHHHHCCCHHCCCCCCCCCCCCCCCCHHHHHHEEEEEEHCCCCCCCC
KDFESKAEDISNYVNKSDHVVMDSGSVAFGKAICMTGDGPGLYDLAVMNGQKWANVDVEL
HHHHHHHHHHHHHHCCCCEEEEECCCEEECEEEEEECCCCCEEEEEEECCCEEECEEEEE
ECGSGVVPFVYSMKNKVHSVQWAMGIELLLLTDPRKVIMTTDNPNAGPFTKYPQLITWLM
ECCCCCHHHHHHHHHHHHEEEEECCEEEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHH
SKKAREDTMKLCHKWAGERSGLAGNDKELSLYDLATVTRATPAKAIGMGHRKGHLSPGAD
HHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEHHHHHCCCCHHHHCCCCCCCCCCCCCC
ADITVYDISPDYNSSDYAAIEKAFTTALFTIKDGEVITKDGRIIETPKGRTYYVDAKFNE
CEEEEEECCCCCCCCHHHHHHHHHEEEEEEEECCCEEECCCEEEECCCCCEEEEECCCCH
EIQKEIIADVQDWFRRYYSIGFSNYPVPDLYLTKPTPLNINVR
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCEEEEEC
>Mature Secondary Structure 
TKMVIKGGTVYDPLNGIDGEVMDIFIKDGKIVENLSDGELKDAKILDVKGKVVMPGGVD
CEEEEECCCEECCCCCCCCCEEEEEEECCCEECCCCCCCCCCCEEEEECCCEEECCCCC
SHTHVAGPKVNTGRVMCPEDHYKSPLKKTHNTHCGSGEIVPSTYAQGYKYSSMGYTTLFE
CCCCCCCCCCCCCEEECCHHHHCCHHHHHCCCCCCCCCCCCCHHHCCEEECCCCHHHHHH
AAVPPMLARHTHEEFKVMPIVDKAGYLLLGSNWFVMKYLKEGNVEKAAAYVAWALETTKT
HHCCHHHHHCCCCCEEEEEEECCCCEEEECCCEEEEEEECCCCHHHHHEEEEEEEECCCC
FGIKLVNPAGVESWAWGKNVHSLEEENIHFGISSGEVIRGLGAVNEMLGLPMSIHLHANN
CCEEEECCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCEEEEEEECC
LGHPGNWEFTIDTMDVAKNIKPAVNKQGYDNGVKTKYSHEREQSLYMTHMQFHSFGGTSW
CCCCCCEEEEEEHHHHHHCCCHHCCCCCCCCCCCCCCCCHHHHHHEEEEEEHCCCCCCCC
KDFESKAEDISNYVNKSDHVVMDSGSVAFGKAICMTGDGPGLYDLAVMNGQKWANVDVEL
HHHHHHHHHHHHHHCCCCEEEEECCCEEECEEEEEECCCCCEEEEEEECCCEEECEEEEE
ECGSGVVPFVYSMKNKVHSVQWAMGIELLLLTDPRKVIMTTDNPNAGPFTKYPQLITWLM
ECCCCCHHHHHHHHHHHHEEEEECCEEEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHH
SKKAREDTMKLCHKWAGERSGLAGNDKELSLYDLATVTRATPAKAIGMGHRKGHLSPGAD
HHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEHHHHHCCCCHHHHCCCCCCCCCCCCCC
ADITVYDISPDYNSSDYAAIEKAFTTALFTIKDGEVITKDGRIIETPKGRTYYVDAKFNE
CEEEEEECCCCCCCCHHHHHHHHHEEEEEEEECCCEEECCCEEEECCCCCEEEEECCCCH
EIQKEIIADVQDWFRRYYSIGFSNYPVPDLYLTKPTPLNINVR
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: formylmethanofuran; H2O; acceptor

Specific reaction: formylmethanofuran + H2O + acceptor = CO2 + methanofuran + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]