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The map label for this gene is recG [H]

Identifier: 45358023

GI number: 45358023

Start: 456701

End: 458044

Strand: Direct

Name: recG [H]

Synonym: MMP0460

Alternate gene names: 45358023

Gene position: 456701-458044 (Clockwise)

Preceding gene: 45358022

Following gene: 45358029

Centisome position: 27.49

GC content: 30.58

Gene sequence:

>1344_bases
GTGACCAAACTTACAAAAAAACAAGTAACTGATTTAATAAATACTGGGGAAGGTTATACTTTAGAATTTAAAGAATCGCT
TAATGCATCATTAGCTAAAGAAATATGTGCTTTTGCGAATTCTGATGGTGGCCATATTTTATTGGGTGTCACTGATTCAG
GCGATATAACTGGATATCCATTGAGTAATCAAGACGATGCAAGAATAACGGATATCGCTCGAAACATGGACCCTAGTTTT
TCAGTAAATCTTGAAAAAGTAGATAATGTTGTAGTAATAACTGTACCAAAAGGCGAAAATAAGCCCTATTCTACTGGCGG
ATTATATTATGTTAGGAATGGATCACAATCTCAAAAATTAAAACGTGAAGAAGTAATTGAACTTTTTAAATACAATGGAT
TAATCTCTTTTGAAGAAATACCAAATAAAGAATTTGATTTAAAGAAAGATCTTAATAATTCAGCGCTTAATAATTTTATA
ACTGCGTCTGGAATTACAAATAAGTTAAAAAAAGAAGATTTATTGAATAATTTATATCTATTAAAAGATGGATTTCTTAA
AAATGCTGGTGTGTTATATTTTTGTAATAATTCCACTAAATTTTTTAGAAATGCACATATAACTTGTGTACTCTACGAAG
GCACCAGTAAATCAAATATTTTAGATAGAAAGGATTTTTCAAAAGATATTTATTCCAATTTTAATGATTCATTTGATTAC
ATCTGTTCAAAACTTAATACGGAATATATAATTGGCAAAGAGCGAGTTGAAAGACTGGAACTTCCAAAAGAGGCCATTAG
GGAAGCTTTGGTAAATTCTATTGCCCATAGAGATTATTTTTCTTCAGGCCATATTCAGGTAGATATATTCCAGGATAAAC
TTGAAATTTCAAATCCAGGGGGACTAGTTTTAGGTCTTTCATATTCTGAACTTGGTAAAAGAAGTATTCCTCGTAATCCT
TTACTTGCAGATTTAATGCTTAGATCAAAACTTGTTGAAAGGGTGGGTTCTGGAATAATTCGGATTAGGGAATCCATGGA
AAGCTACGGGTTAAACTGTGAATTTAATGTTTCTGAAAATTATTTTTCAACAGTATTGGGGCGTAAAAAAGGCTTTAAAT
TCCCAGTTAGTTTTTCAAGCACTAATGCAGTTAGCAGATCCGATAAAATTATTGCATTAATAATGGAAAATCCAGAAATA
ACAATTTTAGAAATTAGTAAGTTACTTAATTTAAGTCATAGTACTGTTAGAAATGAAATAAAAGTATTAAAAGAAAACGG
AATAGTTAAACGAGTAGGTCCTACAAAGGGGGGCCATTGGGAAGTAGTTGATACTAAGAAGTAA

Upstream 100 bases:

>100_bases
AAGATAAATTAATTTTTAGGACCTATTTTTTCAATTTTCACATGGAAACCTATTAAAAAATGAAATAACAATTAAGATAT
ATTGACAAATAGGGGATACT

Downstream 100 bases:

>100_bases
CTTAGAAATACCTTAGAAATACCTTAGAAATACCTTAGAAATACCTTAGAAATACCTTAGAAATACCTTAGAAATACCTT
AGAAATACCTTAGATTAACT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MTKLTKKQVTDLINTGEGYTLEFKESLNASLAKEICAFANSDGGHILLGVTDSGDITGYPLSNQDDARITDIARNMDPSF
SVNLEKVDNVVVITVPKGENKPYSTGGLYYVRNGSQSQKLKREEVIELFKYNGLISFEEIPNKEFDLKKDLNNSALNNFI
TASGITNKLKKEDLLNNLYLLKDGFLKNAGVLYFCNNSTKFFRNAHITCVLYEGTSKSNILDRKDFSKDIYSNFNDSFDY
ICSKLNTEYIIGKERVERLELPKEAIREALVNSIAHRDYFSSGHIQVDIFQDKLEISNPGGLVLGLSYSELGKRSIPRNP
LLADLMLRSKLVERVGSGIIRIRESMESYGLNCEFNVSENYFSTVLGRKKGFKFPVSFSSTNAVSRSDKIIALIMENPEI
TILEISKLLNLSHSTVRNEIKVLKENGIVKRVGPTKGGHWEVVDTKK

Sequences:

>Translated_447_residues
MTKLTKKQVTDLINTGEGYTLEFKESLNASLAKEICAFANSDGGHILLGVTDSGDITGYPLSNQDDARITDIARNMDPSF
SVNLEKVDNVVVITVPKGENKPYSTGGLYYVRNGSQSQKLKREEVIELFKYNGLISFEEIPNKEFDLKKDLNNSALNNFI
TASGITNKLKKEDLLNNLYLLKDGFLKNAGVLYFCNNSTKFFRNAHITCVLYEGTSKSNILDRKDFSKDIYSNFNDSFDY
ICSKLNTEYIIGKERVERLELPKEAIREALVNSIAHRDYFSSGHIQVDIFQDKLEISNPGGLVLGLSYSELGKRSIPRNP
LLADLMLRSKLVERVGSGIIRIRESMESYGLNCEFNVSENYFSTVLGRKKGFKFPVSFSSTNAVSRSDKIIALIMENPEI
TILEISKLLNLSHSTVRNEIKVLKENGIVKRVGPTKGGHWEVVDTKK
>Mature_446_residues
TKLTKKQVTDLINTGEGYTLEFKESLNASLAKEICAFANSDGGHILLGVTDSGDITGYPLSNQDDARITDIARNMDPSFS
VNLEKVDNVVVITVPKGENKPYSTGGLYYVRNGSQSQKLKREEVIELFKYNGLISFEEIPNKEFDLKKDLNNSALNNFIT
ASGITNKLKKEDLLNNLYLLKDGFLKNAGVLYFCNNSTKFFRNAHITCVLYEGTSKSNILDRKDFSKDIYSNFNDSFDYI
CSKLNTEYIIGKERVERLELPKEAIREALVNSIAHRDYFSSGHIQVDIFQDKLEISNPGGLVLGLSYSELGKRSIPRNPL
LADLMLRSKLVERVGSGIIRIRESMESYGLNCEFNVSENYFSTVLGRKKGFKFPVSFSSTNAVSRSDKIIALIMENPEIT
ILEISKLLNLSHSTVRNEIKVLKENGIVKRVGPTKGGHWEVVDTKK

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG2865

COG function: function code K; Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase ATP-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 50199; Mature: 50068

Theoretical pI: Translated: 8.40; Mature: 8.40

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKLTKKQVTDLINTGEGYTLEFKESLNASLAKEICAFANSDGGHILLGVTDSGDITGYP
CCCCCHHHHHHHHHCCCCEEEEEHHHCCHHHHHHHHHHCCCCCCEEEEEEECCCCEECCC
LSNQDDARITDIARNMDPSFSVNLEKVDNVVVITVPKGENKPYSTGGLYYVRNGSQSQKL
CCCCCCCHHHHHHHCCCCCCEEEHHHHCCEEEEEECCCCCCCCCCCCEEEEECCCHHHHH
KREEVIELFKYNGLISFEEIPNKEFDLKKDLNNSALNNFITASGITNKLKKEDLLNNLYL
HHHHHHHHHHHCCEEEHHHCCCCCCCHHHCCCHHHHHHEEECCCHHHHHHHHHHHHCEEE
LKDGFLKNAGVLYFCNNSTKFFRNAHITCVLYEGTSKSNILDRKDFSKDIYSNFNDSFDY
EECCCCCCCCEEEEECCCCEEEECCEEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCHHH
ICSKLNTEYIIGKERVERLELPKEAIREALVNSIAHRDYFSSGHIQVDIFQDKLEISNPG
HHHHCCCEEEECHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECEEEECCCC
GLVLGLSYSELGKRSIPRNPLLADLMLRSKLVERVGSGIIRIRESMESYGLNCEFNVSEN
CEEEECCHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEECCHH
YFSTVLGRKKGFKFPVSFSSTNAVSRSDKIIALIMENPEITILEISKLLNLSHSTVRNEI
HHHHHHHCCCCCEEEEECCCCCCCCCCCCEEEEEECCCCEEEEEHHHHHCCHHHHHHHHH
KVLKENGIVKRVGPTKGGHWEVVDTKK
HHHHCCCEEEECCCCCCCEEEEEECCC
>Mature Secondary Structure 
TKLTKKQVTDLINTGEGYTLEFKESLNASLAKEICAFANSDGGHILLGVTDSGDITGYP
CCCCHHHHHHHHHCCCCEEEEEHHHCCHHHHHHHHHHCCCCCCEEEEEEECCCCEECCC
LSNQDDARITDIARNMDPSFSVNLEKVDNVVVITVPKGENKPYSTGGLYYVRNGSQSQKL
CCCCCCCHHHHHHHCCCCCCEEEHHHHCCEEEEEECCCCCCCCCCCCEEEEECCCHHHHH
KREEVIELFKYNGLISFEEIPNKEFDLKKDLNNSALNNFITASGITNKLKKEDLLNNLYL
HHHHHHHHHHHCCEEEHHHCCCCCCCHHHCCCHHHHHHEEECCCHHHHHHHHHHHHCEEE
LKDGFLKNAGVLYFCNNSTKFFRNAHITCVLYEGTSKSNILDRKDFSKDIYSNFNDSFDY
EECCCCCCCCEEEEECCCCEEEECCEEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCHHH
ICSKLNTEYIIGKERVERLELPKEAIREALVNSIAHRDYFSSGHIQVDIFQDKLEISNPG
HHHHCCCEEEECHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECEEEECCCC
GLVLGLSYSELGKRSIPRNPLLADLMLRSKLVERVGSGIIRIRESMESYGLNCEFNVSEN
CEEEECCHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEECCHH
YFSTVLGRKKGFKFPVSFSSTNAVSRSDKIIALIMENPEITILEISKLLNLSHSTVRNEI
HHHHHHHCCCCCEEEEECCCCCCCCCCCCEEEEEECCCCEEEEEHHHHHCCHHHHHHHHH
KVLKENGIVKRVGPTKGGHWEVVDTKK
HHHHCCCEEEECCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9603897 [H]