| Definition | Methanococcus maripaludis S2 chromosome, complete genome. |
|---|---|
| Accession | NC_005791 |
| Length | 1,661,137 |
Click here to switch to the map view.
The map label for this gene is wecC [H]
Identifier: 45357916
GI number: 45357916
Start: 348468
End: 349775
Strand: Direct
Name: wecC [H]
Synonym: MMP0353
Alternate gene names: 45357916
Gene position: 348468-349775 (Clockwise)
Preceding gene: 45357915
Following gene: 45357917
Centisome position: 20.98
GC content: 34.1
Gene sequence:
>1308_bases ATGAACGAATTAGGAAATTTAAAAATTGCAGTTTTTGGACAAGGGAAAATGGGTTTACCTTTGGCATCAGTTTTTGCTGA ATACGGAATTAACGTAATTGGCGTGGATATCAACCAAATGGTGGTTGATAATTTAAATAATGGAATAAATCATATCACTG AAGAACCAGGTCTTAGTGAACTTGTTTCAAAAAATGTTGAAAATAAGAAATACACTGCAACAACGGATGGTGTGGGTGCA GCAACAGATGCGGACATAATTGTAATCTTAGTTCCAACTCTGATTGATGATCGAGGGAATATTAAGTTAGATCCTGTTTA CAGTGTTTCAGAAATAATTTCAAAAGGATTAAAAAAAGGAAATATCGTAATAACGGAAGCTACAATGCCTCCGGGAACAA CTGAAAAATTAATTCCAATTTTAGAAAAGTCAGGGTTAAAATTGGGGGAATTTGGGCTGGCACACGCGCCTGAGCGAACA ATGACTGGAACGGCACTAAGGGATATTAAGGGGCAGTACCCAAAAATAATTGGTTGCAGTGACGAAAGAACTCACAATAT TGTTTCAAAACTTTATGATCTGATTAATAAAAAAGGAACGATTAAAATGAGTTCAATTAAAGCTGCGGAAACGGTAAAAG TGTTTGAAGGAGTTTATCGGGATGTAAATATCGGGCTTTCAAATGAAATGGCCCTCTGGTGTGAAGAACATTCAATAAAT GCTTTAGAAGTATTTGAAGCAGCAAATACTCAGCCATTTTGTCATTTCCATACTCCTGGAGCAGGAGTTGGTGGGCACTG TATTCCTGTGTACCCGTGGTTTGTAATAAACACATCAAATGAAGTAAATCCCCGGATTACAAAAACAGCAAGGGAATTAA ATGATTATATGGCACATCACATAGTTGAACTTACAATAAAAGGATTAAATGAGTTTAAAAAATGTTTAAATGGGTCTAAA ATTCTTGTTTTAGGTTTGACCTTCAGGGGTGGAGTTAAGGAATTCATGAAAAGTGCGGCAATTCCCATAATCAACGAATT GAATAGTTTAGGCGCAAATGTTTATTCATACGATCCATTATGTGACGAATTAGATGCAAAAAAGTATAATTCAAAATTAA AAACAGATTTTAATGGAATCGATGCAATTATCGTTACATCGGACCACGAAGAATTTAAACACTTGGACTTTGAAAAAATT TCAAAAGAAGTTTCAACAAAATTAATTGTTGATGGAAGAAATATTATAAATGTTTCAAATGCAACTGAAAATGGATTTAG GGTTATTAAAGTTGGAAATTTGAAATAA
Upstream 100 bases:
>100_bases AACAGCCGTTAGTTACTGGATTAGATGGGTTAAATGCATTAGAAACCGCAATTTATGCTTTGAAAAGCTCTAACGGTAAT TAAAAATCAGGAGGTTAAAA
Downstream 100 bases:
>100_bases ATTTTTTATTTCATTGTGAAATTATGGATTTAAAAAAGAAGGTACTCCTTAATTCTAGTCAATTATTTGGCGGACAGTTT TTACATAGTATTATTTCCTA
Product: UDP-glucose/GDP-mannose dehydrogenase-like protein
Products: UDP-N-acetyl-D-mannosaminuronic-acid; NADH; Proton [C]
Alternate protein names: UDP-ManNAc 6-dehydrogenase [H]
Number of amino acids: Translated: 435; Mature: 435
Protein sequence:
>435_residues MNELGNLKIAVFGQGKMGLPLASVFAEYGINVIGVDINQMVVDNLNNGINHITEEPGLSELVSKNVENKKYTATTDGVGA ATDADIIVILVPTLIDDRGNIKLDPVYSVSEIISKGLKKGNIVITEATMPPGTTEKLIPILEKSGLKLGEFGLAHAPERT MTGTALRDIKGQYPKIIGCSDERTHNIVSKLYDLINKKGTIKMSSIKAAETVKVFEGVYRDVNIGLSNEMALWCEEHSIN ALEVFEAANTQPFCHFHTPGAGVGGHCIPVYPWFVINTSNEVNPRITKTARELNDYMAHHIVELTIKGLNEFKKCLNGSK ILVLGLTFRGGVKEFMKSAAIPIINELNSLGANVYSYDPLCDELDAKKYNSKLKTDFNGIDAIIVTSDHEEFKHLDFEKI SKEVSTKLIVDGRNIINVSNATENGFRVIKVGNLK
Sequences:
>Translated_435_residues MNELGNLKIAVFGQGKMGLPLASVFAEYGINVIGVDINQMVVDNLNNGINHITEEPGLSELVSKNVENKKYTATTDGVGA ATDADIIVILVPTLIDDRGNIKLDPVYSVSEIISKGLKKGNIVITEATMPPGTTEKLIPILEKSGLKLGEFGLAHAPERT MTGTALRDIKGQYPKIIGCSDERTHNIVSKLYDLINKKGTIKMSSIKAAETVKVFEGVYRDVNIGLSNEMALWCEEHSIN ALEVFEAANTQPFCHFHTPGAGVGGHCIPVYPWFVINTSNEVNPRITKTARELNDYMAHHIVELTIKGLNEFKKCLNGSK ILVLGLTFRGGVKEFMKSAAIPIINELNSLGANVYSYDPLCDELDAKKYNSKLKTDFNGIDAIIVTSDHEEFKHLDFEKI SKEVSTKLIVDGRNIINVSNATENGFRVIKVGNLK >Mature_435_residues MNELGNLKIAVFGQGKMGLPLASVFAEYGINVIGVDINQMVVDNLNNGINHITEEPGLSELVSKNVENKKYTATTDGVGA ATDADIIVILVPTLIDDRGNIKLDPVYSVSEIISKGLKKGNIVITEATMPPGTTEKLIPILEKSGLKLGEFGLAHAPERT MTGTALRDIKGQYPKIIGCSDERTHNIVSKLYDLINKKGTIKMSSIKAAETVKVFEGVYRDVNIGLSNEMALWCEEHSIN ALEVFEAANTQPFCHFHTPGAGVGGHCIPVYPWFVINTSNEVNPRITKTARELNDYMAHHIVELTIKGLNEFKKCLNGSK ILVLGLTFRGGVKEFMKSAAIPIINELNSLGANVYSYDPLCDELDAKKYNSKLKTDFNGIDAIIVTSDHEEFKHLDFEKI SKEVSTKLIVDGRNIINVSNATENGFRVIKVGNLK
Specific function: Catalyzes the four-electron oxidation of UDP-N-acetyl-D- mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N- acetylmannosaminuronic acid (UDP-ManNAcA) [H]
COG id: COG0677
COG function: function code M; UDP-N-acetyl-D-mannosaminuronate dehydrogenase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]
Homologues:
Organism=Homo sapiens, GI4507813, Length=463, Percent_Identity=22.6781857451404, Blast_Score=79, Evalue=7e-15, Organism=Escherichia coli, GI48994968, Length=432, Percent_Identity=30.5555555555556, Blast_Score=181, Evalue=1e-46, Organism=Escherichia coli, GI1788340, Length=406, Percent_Identity=23.3990147783251, Blast_Score=75, Evalue=8e-15, Organism=Caenorhabditis elegans, GI17560350, Length=462, Percent_Identity=24.025974025974, Blast_Score=77, Evalue=2e-14, Organism=Drosophila melanogaster, GI17136908, Length=464, Percent_Identity=23.7068965517241, Blast_Score=88, Evalue=1e-17,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR008927 - InterPro: IPR016040 - InterPro: IPR017476 - InterPro: IPR014027 - InterPro: IPR014026 - InterPro: IPR014028 - InterPro: IPR001732 [H]
Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]
EC number: 1.1.1.- [C]
Molecular weight: Translated: 47615; Mature: 47615
Theoretical pI: Translated: 6.44; Mature: 6.44
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.4 %Cys (Translated Protein) 2.1 %Met (Translated Protein) 3.4 %Cys+Met (Translated Protein) 1.4 %Cys (Mature Protein) 2.1 %Met (Mature Protein) 3.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNELGNLKIAVFGQGKMGLPLASVFAEYGINVIGVDINQMVVDNLNNGINHITEEPGLSE CCCCCCEEEEEEECCCCCCHHHHHHHHCCCEEEEECHHHHHHHHHCCCHHHHCCCCCHHH LVSKNVENKKYTATTDGVGAATDADIIVILVPTLIDDRGNIKLDPVYSVSEIISKGLKKG HHHCCCCCCEEEECCCCCCCCCCCCEEEEEEEEHCCCCCCEEECCCCCHHHHHHHCCCCC NIVITEATMPPGTTEKLIPILEKSGLKLGEFGLAHAPERTMTGTALRDIKGQYPKIIGCS CEEEEECCCCCCCHHHHHHHHHHCCCEECCCCCCCCCCCCCCHHHHHHHCCCCCEEEECC DERTHNIVSKLYDLINKKGTIKMSSIKAAETVKVFEGVYRDVNIGLSNEMALWCEEHSIN CHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCC ALEVFEAANTQPFCHFHTPGAGVGGHCIPVYPWFVINTSNEVNPRITKTARELNDYMAHH CEEHHHHCCCCCEEEECCCCCCCCCCEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHH IVELTIKGLNEFKKCLNGSKILVLGLTFRGGVKEFMKSAAIPIINELNSLGANVYSYDPL HHHHHHHHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHCCCHHHHHHHHHCCCCEECCCC CDELDAKKYNSKLKTDFNGIDAIIVTSDHEEFKHLDFEKISKEVSTKLIVDGRNIINVSN HHHHHHHHHCCHHCCCCCCCEEEEEECCHHHHHCCCHHHHHHHHCCEEEECCCCEEEECC ATENGFRVIKVGNLK CCCCCEEEEEECCCC >Mature Secondary Structure MNELGNLKIAVFGQGKMGLPLASVFAEYGINVIGVDINQMVVDNLNNGINHITEEPGLSE CCCCCCEEEEEEECCCCCCHHHHHHHHCCCEEEEECHHHHHHHHHCCCHHHHCCCCCHHH LVSKNVENKKYTATTDGVGAATDADIIVILVPTLIDDRGNIKLDPVYSVSEIISKGLKKG HHHCCCCCCEEEECCCCCCCCCCCCEEEEEEEEHCCCCCCEEECCCCCHHHHHHHCCCCC NIVITEATMPPGTTEKLIPILEKSGLKLGEFGLAHAPERTMTGTALRDIKGQYPKIIGCS CEEEEECCCCCCCHHHHHHHHHHCCCEECCCCCCCCCCCCCCHHHHHHHCCCCCEEEECC DERTHNIVSKLYDLINKKGTIKMSSIKAAETVKVFEGVYRDVNIGLSNEMALWCEEHSIN CHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCC ALEVFEAANTQPFCHFHTPGAGVGGHCIPVYPWFVINTSNEVNPRITKTARELNDYMAHH CEEHHHHCCCCCEEEECCCCCCCCCCEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHH IVELTIKGLNEFKKCLNGSKILVLGLTFRGGVKEFMKSAAIPIINELNSLGANVYSYDPL HHHHHHHHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHCCCHHHHHHHHHCCCCEECCCC CDELDAKKYNSKLKTDFNGIDAIIVTSDHEEFKHLDFEKISKEVSTKLIVDGRNIINVSN HHHHHHHHHCCHHCCCCCCCEEEEEECCHHHHHCCCHHHHHHHHCCEEEECCCCEEEECC ATENGFRVIKVGNLK CCCCCEEEEEECCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: UDP-N-acetyl-D-mannosamine; NAD [C]
Specific reaction: UDP-N-acetyl-D-mannosamine + NAD = UDP-N-acetyl-D-mannosaminuronic-acid + NADH + Proton [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA