Click here to switch to the map view.

The map label for this gene is glmU [H]

Identifier: 45357913

GI number: 45357913

Start: 345820

End: 346410

Strand: Direct

Name: glmU [H]

Synonym: MMP0350

Alternate gene names: 45357913

Gene position: 345820-346410 (Clockwise)

Preceding gene: 45357905

Following gene: 45357914

Centisome position: 20.82

GC content: 33.67

Gene sequence:

>591_bases
ATGGGTAGTTATCAGGCACATCCTACCGCACATGTGGAAAATAATTCCAAAATCGGAGATAATACTAGAATTTGGCATTT
TTCACACATTCGTGAAAATAGTGAAATTGGAAAAAACTGTAACCTTGGAAAAGGTGTTTATATAGATACCAATGTCAAAA
TCGGAAACAATGTCAAAATTCAAAACAATGTTTCAGTATATGCAGGGGTTGAAGTAGAAGATGACGTTTTTTTAGGCCCC
CACATGGTATTTACAAATGATTTATATCCTCGGGCATTTAACAATAATTGGAAAATTGTAAGAACAAAAGTAAAAACGGG
AGCTTCAATTGGCGCAAATTCAACAGTAGTTTGTGGAATCACAATTGGAAATTATGCAATGATCGGATCCGGATCGGTTG
TTACCAAAGACGTTCCAGATTATGCTTTAGTTTATGGTAATCCTGCAAGATTAAATGGTTTTGTATGTACTTGTGGCAAA
AAATTGGAAAATATGGTCGAAAAAACTGAGAAACTGGTTAAATATCGATGTAGTAATTGTAGTACTATAGTGGAAATTAA
AAAAGAAGATCATGATTTATTGGGGGATTAA

Upstream 100 bases:

>100_bases
AAGACAGCTTATGTTTATTTACTTATTAAGTTTTTTATACCTGTTTTTACTTCATATGTGTTGTATACTAAAAGATTATT
TTACTAAAAGTGTGATATTT

Downstream 100 bases:

>100_bases
TATGATACCTATTGCAAAACCCATACTAGGTAATGAAGAGATTTCTGCAGTAACTGATGTGTTAAAAAGCGGAATGATTG
CACAGGGTAAAGAAGTTGAA

Product: hexapeptide repeat-containing transferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase; Glucosamine-1-phosphate N-acetyltransferase [H]

Number of amino acids: Translated: 196; Mature: 195

Protein sequence:

>196_residues
MGSYQAHPTAHVENNSKIGDNTRIWHFSHIRENSEIGKNCNLGKGVYIDTNVKIGNNVKIQNNVSVYAGVEVEDDVFLGP
HMVFTNDLYPRAFNNNWKIVRTKVKTGASIGANSTVVCGITIGNYAMIGSGSVVTKDVPDYALVYGNPARLNGFVCTCGK
KLENMVEKTEKLVKYRCSNCSTIVEIKKEDHDLLGD

Sequences:

>Translated_196_residues
MGSYQAHPTAHVENNSKIGDNTRIWHFSHIRENSEIGKNCNLGKGVYIDTNVKIGNNVKIQNNVSVYAGVEVEDDVFLGP
HMVFTNDLYPRAFNNNWKIVRTKVKTGASIGANSTVVCGITIGNYAMIGSGSVVTKDVPDYALVYGNPARLNGFVCTCGK
KLENMVEKTEKLVKYRCSNCSTIVEIKKEDHDLLGD
>Mature_195_residues
GSYQAHPTAHVENNSKIGDNTRIWHFSHIRENSEIGKNCNLGKGVYIDTNVKIGNNVKIQNNVSVYAGVEVEDDVFLGPH
MVFTNDLYPRAFNNNWKIVRTKVKTGASIGANSTVVCGITIGNYAMIGSGSVVTKDVPDYALVYGNPARLNGFVCTCGKK
LENMVEKTEKLVKYRCSNCSTIVEIKKEDHDLLGD

Specific function: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-GlcNAc. Responsible for the acetylation of Glc-N-1-P to give GlcNAc-1-P and for the uridyl transfer from UTP to GlcNAc-1-P which produces UDP-GlcNAc [H]

COG id: COG0110

COG function: function code R; Acetyltransferase (isoleucine patch superfamily)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transferase hexapeptide repeat family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005882
- InterPro:   IPR018357
- InterPro:   IPR005835
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.23; =2.3.1.157 [H]

Molecular weight: Translated: 21588; Mature: 21457

Theoretical pI: Translated: 8.12; Mature: 8.12

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSYQAHPTAHVENNSKIGDNTRIWHFSHIRENSEIGKNCNLGKGVYIDTNVKIGNNVKI
CCCCCCCCCEEECCCCCCCCCCEEEEEHHCCCCCCCCCCCCCCCCEEEECCEEECCEEEE
QNNVSVYAGVEVEDDVFLGPHMVFTNDLYPRAFNNNWKIVRTKVKTGASIGANSTVVCGI
ECCCEEEECCEECCCEEECCEEEEECCCCCCEECCCEEEEEEEECCCCCCCCCCEEEEEE
TIGNYAMIGSGSVVTKDVPDYALVYGNPARLNGFVCTCGKKLENMVEKTEKLVKYRCSNC
EECCEEEECCCCEEEECCCCEEEEECCHHHCCCEEEECCHHHHHHHHHHHHHHHHHCCCC
STIVEIKKEDHDLLGD
CEEEEEECCCCCCCCC
>Mature Secondary Structure 
GSYQAHPTAHVENNSKIGDNTRIWHFSHIRENSEIGKNCNLGKGVYIDTNVKIGNNVKI
CCCCCCCCEEECCCCCCCCCCEEEEEHHCCCCCCCCCCCCCCCCEEEECCEEECCEEEE
QNNVSVYAGVEVEDDVFLGPHMVFTNDLYPRAFNNNWKIVRTKVKTGASIGANSTVVCGI
ECCCEEEECCEECCCEEECCEEEEECCCCCCEECCCEEEEEEEECCCCCCCCCCEEEEEE
TIGNYAMIGSGSVVTKDVPDYALVYGNPARLNGFVCTCGKKLENMVEKTEKLVKYRCSNC
EECCEEEECCCCEEEECCCCEEEEECCHHHCCCEEEECCHHHHHHHHHHHHHHHHHCCCC
STIVEIKKEDHDLLGD
CEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA