Click here to switch to the map view.

The map label for this gene is fecC [C]

Identifier: 45357760

GI number: 45357760

Start: 205077

End: 206036

Strand: Direct

Name: fecC [C]

Synonym: MMP0197

Alternate gene names: 45357760

Gene position: 205077-206036 (Clockwise)

Preceding gene: 45357759

Following gene: 45357761

Centisome position: 12.35

GC content: 37.4

Gene sequence:

>960_bases
GTGATAATATTGAATAAAAATTATGTTTTTCCTTTTTTGTTTGCAGGCGTGTTTTTATTTTCCCTGTTTGTTGGAAGATA
CATGTTTGATCCTTCTTTAATTTTTACAAATTCACTTGCAAACAATATTTTTTTTGATATTCGGCTTCCAAGGGCGATTG
CAGTATCACTTGCAGGGGCATCTTTAGCGCTTGCGGGAGTTTCTTTTCAAAATATTTTTAAAAATTACCTTGCAGGCCCA
AATATTTTGGGAGTTACAAGCGGGTCCGCATTTGGTGCATCTATTGCAATTTTATTTTTTGCGTACAATCCTTATCTGGT
ACAGTTCTCCGCGTTTATATTTGGTGTTATTGCAGTATATATTGCATATAAACTCAGCAGTCTTTTAAAAAGTGGAATTG
TTGGGCTTATTCTTTCTGGAATGGCGATTTCTGCATTTTTTTCTGCAATGATCGGCCTTATAAAATACGTTGCAGACCCT
TATGAAAAACTGCCAACGATAGTTTTCTGGCTTCTTGGAAGTTTTGTAGGCCTTCGATGGGTGGATTTGGGAATATCGGT
TATACCCATGTTAATCGGGATTATCGGGCTTGTAATGTTAAAATGGGTTTTTAACATCCTTGCAACAGGGGATGAAAATG
CAAAAAGTTTAGGGGTGGATTCAAAAAAACTGAAAAATATAACGATATTTCTTGCAACACTTGCTGCATCTGCATCGACT
TCGCTTGCAGGGATGATTCAGTGGGTCGGCGTTGTAAGTCCACATATTGCAAGGCTTTTGGTGGGGGTAGACAACAGGAA
ACTCGTTCCTGCATCTGCTTTTGTAGGTGCTACACTTCTCTTACTCTGCGACACGCTTGCAAGAACTTTAACGCCTTCTG
AAATTCCAATAAGTATTATAACTTCGTTTATTGGTGCACCAATTTTGATTATTATTTTATCAAAAAGAGGGGTGAAATAA

Upstream 100 bases:

>100_bases
CTTCACCCTGATATGTATACTGATGTTGATATCTTAAATCTTACATCATCAGAATATGAACGGTTTTTCAATGTAAGTAT
TGACGAAGTTACGCTCGTTG

Downstream 100 bases:

>100_bases
TGTTGAGAATTGAAAATATAAATTTTAATTACGGGAAAAACAAAATATTGAATGATTGTAGTTTTAAACTTGACAGTGGA
ATTGGATGTATACTTGGGCC

Product: ABC-type iron(III) transport system permease

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MIILNKNYVFPFLFAGVFLFSLFVGRYMFDPSLIFTNSLANNIFFDIRLPRAIAVSLAGASLALAGVSFQNIFKNYLAGP
NILGVTSGSAFGASIAILFFAYNPYLVQFSAFIFGVIAVYIAYKLSSLLKSGIVGLILSGMAISAFFSAMIGLIKYVADP
YEKLPTIVFWLLGSFVGLRWVDLGISVIPMLIGIIGLVMLKWVFNILATGDENAKSLGVDSKKLKNITIFLATLAASAST
SLAGMIQWVGVVSPHIARLLVGVDNRKLVPASAFVGATLLLLCDTLARTLTPSEIPISIITSFIGAPILIIILSKRGVK

Sequences:

>Translated_319_residues
MIILNKNYVFPFLFAGVFLFSLFVGRYMFDPSLIFTNSLANNIFFDIRLPRAIAVSLAGASLALAGVSFQNIFKNYLAGP
NILGVTSGSAFGASIAILFFAYNPYLVQFSAFIFGVIAVYIAYKLSSLLKSGIVGLILSGMAISAFFSAMIGLIKYVADP
YEKLPTIVFWLLGSFVGLRWVDLGISVIPMLIGIIGLVMLKWVFNILATGDENAKSLGVDSKKLKNITIFLATLAASAST
SLAGMIQWVGVVSPHIARLLVGVDNRKLVPASAFVGATLLLLCDTLARTLTPSEIPISIITSFIGAPILIIILSKRGVK
>Mature_319_residues
MIILNKNYVFPFLFAGVFLFSLFVGRYMFDPSLIFTNSLANNIFFDIRLPRAIAVSLAGASLALAGVSFQNIFKNYLAGP
NILGVTSGSAFGASIAILFFAYNPYLVQFSAFIFGVIAVYIAYKLSSLLKSGIVGLILSGMAISAFFSAMIGLIKYVADP
YEKLPTIVFWLLGSFVGLRWVDLGISVIPMLIGIIGLVMLKWVFNILATGDENAKSLGVDSKKLKNITIFLATLAASAST
SLAGMIQWVGVVSPHIARLLVGVDNRKLVPASAFVGATLLLLCDTLARTLTPSEIPISIITSFIGAPILIIILSKRGVK

Specific function: Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790741, Length=291, Percent_Identity=30.9278350515464, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1790740, Length=312, Percent_Identity=31.0897435897436, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1786805, Length=308, Percent_Identity=29.8701298701299, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1788004, Length=303, Percent_Identity=32.013201320132, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1786347, Length=275, Percent_Identity=28.7272727272727, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1786804, Length=279, Percent_Identity=26.8817204301075, Blast_Score=85, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 34237; Mature: 34237

Theoretical pI: Translated: 10.31; Mature: 10.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIILNKNYVFPFLFAGVFLFSLFVGRYMFDPSLIFTNSLANNIFFDIRLPRAIAVSLAGA
CEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEEEECCHHHHHHHCCH
SLALAGVSFQNIFKNYLAGPNILGVTSGSAFGASIAILFFAYNPYLVQFSAFIFGVIAVY
HHHHHCCHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
IAYKLSSLLKSGIVGLILSGMAISAFFSAMIGLIKYVADPYEKLPTIVFWLLGSFVGLRW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
VDLGISVIPMLIGIIGLVMLKWVFNILATGDENAKSLGVDSKKLKNITIFLATLAASAST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHH
SLAGMIQWVGVVSPHIARLLVGVDNRKLVPASAFVGATLLLLCDTLARTLTPSEIPISII
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
TSFIGAPILIIILSKRGVK
HHHHHHHHEEHEECCCCCC
>Mature Secondary Structure
MIILNKNYVFPFLFAGVFLFSLFVGRYMFDPSLIFTNSLANNIFFDIRLPRAIAVSLAGA
CEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEEEECCHHHHHHHCCH
SLALAGVSFQNIFKNYLAGPNILGVTSGSAFGASIAILFFAYNPYLVQFSAFIFGVIAVY
HHHHHCCHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
IAYKLSSLLKSGIVGLILSGMAISAFFSAMIGLIKYVADPYEKLPTIVFWLLGSFVGLRW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
VDLGISVIPMLIGIIGLVMLKWVFNILATGDENAKSLGVDSKKLKNITIFLATLAASAST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHH
SLAGMIQWVGVVSPHIARLLVGVDNRKLVPASAFVGATLLLLCDTLARTLTPSEIPISII
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
TSFIGAPILIIILSKRGVK
HHHHHHHHEEHEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]