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The map label for this gene is arsA

Identifier: 45357726

GI number: 45357726

Start: 172067

End: 173104

Strand: Direct

Name: arsA

Synonym: MMP0163

Alternate gene names: NA

Gene position: 172067-173104 (Clockwise)

Preceding gene: 45357725

Following gene: 45357732

Centisome position: 10.36

GC content: 36.22

Gene sequence:

>1038_bases
TTGGTATTATCTAAAATAAAGGAATCATTGAAAGGAATTACATCTAAAAAACTTGAAAAAGAAAATGGAACCAAGTACAT
CATGTTTGGTGGAAAAGGGGGAGTTGGAAAAACTACAATGAGTGCCGCAACAGGTATTTACTGTGCAGAACAAGGCCTGA
AAACAGTTGTAGTTTCAACCGACCCTGCTCACTCATTAAAAGACAGCTTTGAACAGTCATTTGGTCACGAACCAACAAAA
GTAAACGGCATGGAAAACCTCTATGTTGTAGAAATCGACCCTGAAGTTGCAATGTCAGAATACAAAGAAAAATTAAAATC
ACAAATGGACGAAAACCCAATGATGGGTGGAATGCTCGAAGACCAGCTTGAAATGGCTTCATTATCTCCAGGAACCGACG
AAAGCGCAGCATTTGATGTATTTTTAAAATACATGGACAACAATGAATTTGATGTAGTTGTATTTGATACCGCACCAACA
GGACACACCTTAAGATTCTTAGGCCTTCCAGAACTCATGGACAAATATATGACCAAAATGATCAAGTTCAAAAAACAGAT
GAGCGGTTTTATGAACATGATGAAAAAAGTCATGCCATTTGGCGGTAAAGGCGAAGATGTAGATTACGATAAAGCCTTAG
AAGAAATGGAAGAAATGAAAGCAAGAATTACAAAAGCAAGAGGAATCTTGGCAAACCCTGAAAGAACAGCATTCAGACTT
GTTGTAATTCCTGAAGAAATGAGTATTTTGGAAAGTGAAAGAGCAATGGAATCTTTGAACAAGTTTAAAATACCTGTTGA
TTCAGTTGTTGTAAACCAGATTATTCCTGAAGATGTAGAATGTGACTTCTGTAGAGCAAGAAGAAGCTTACAGGAAAAAA
GACTTGAACTTGTAAAAGAAAAATTCGGCGACAAAGTTATTGCAAATCTTGAATTATTAAGAACTGAGGCAAAAGGACTC
GATGTTTTAAAAGATATTGCACACAAACTCTACGGAGAAGCTAAATCCGAAGAAGAAAAAGAAGTAATTGTAGCTTAA

Upstream 100 bases:

>100_bases
CGAAGAATTAATTAGCCGACTTAAAAATGAACCCTGTTAATTAAAAACCTATAAAAACGTGTAGTTACTAACTATCTTAG
ATTAGCGATAAGGTGATATT

Downstream 100 bases:

>100_bases
TTAAATAAAATACTTTTTTTTATTTTTTTTAAAATTAAAAGATTAAATTAAAGTCCGTTAGCTCTATCGAGGACTATATC
TATAATTCTATCATCTGCAC

Product: arsenite-activated ATPase ArsA

Products: NA

Alternate protein names: Arsenical resistance ATPase; Arsenite-translocating ATPase; Arsenite-transporting ATPase [H]

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MVLSKIKESLKGITSKKLEKENGTKYIMFGGKGGVGKTTMSAATGIYCAEQGLKTVVVSTDPAHSLKDSFEQSFGHEPTK
VNGMENLYVVEIDPEVAMSEYKEKLKSQMDENPMMGGMLEDQLEMASLSPGTDESAAFDVFLKYMDNNEFDVVVFDTAPT
GHTLRFLGLPELMDKYMTKMIKFKKQMSGFMNMMKKVMPFGGKGEDVDYDKALEEMEEMKARITKARGILANPERTAFRL
VVIPEEMSILESERAMESLNKFKIPVDSVVVNQIIPEDVECDFCRARRSLQEKRLELVKEKFGDKVIANLELLRTEAKGL
DVLKDIAHKLYGEAKSEEEKEVIVA

Sequences:

>Translated_345_residues
MVLSKIKESLKGITSKKLEKENGTKYIMFGGKGGVGKTTMSAATGIYCAEQGLKTVVVSTDPAHSLKDSFEQSFGHEPTK
VNGMENLYVVEIDPEVAMSEYKEKLKSQMDENPMMGGMLEDQLEMASLSPGTDESAAFDVFLKYMDNNEFDVVVFDTAPT
GHTLRFLGLPELMDKYMTKMIKFKKQMSGFMNMMKKVMPFGGKGEDVDYDKALEEMEEMKARITKARGILANPERTAFRL
VVIPEEMSILESERAMESLNKFKIPVDSVVVNQIIPEDVECDFCRARRSLQEKRLELVKEKFGDKVIANLELLRTEAKGL
DVLKDIAHKLYGEAKSEEEKEVIVA
>Mature_345_residues
MVLSKIKESLKGITSKKLEKENGTKYIMFGGKGGVGKTTMSAATGIYCAEQGLKTVVVSTDPAHSLKDSFEQSFGHEPTK
VNGMENLYVVEIDPEVAMSEYKEKLKSQMDENPMMGGMLEDQLEMASLSPGTDESAAFDVFLKYMDNNEFDVVVFDTAPT
GHTLRFLGLPELMDKYMTKMIKFKKQMSGFMNMMKKVMPFGGKGEDVDYDKALEEMEEMKARITKARGILANPERTAFRL
VVIPEEMSILESERAMESLNKFKIPVDSVVVNQIIPEDVECDFCRARRSLQEKRLELVKEKFGDKVIANLELLRTEAKGL
DVLKDIAHKLYGEAKSEEEKEVIVA

Specific function: Anion-transporting ATPase. Catalyzes the extrusion of arsenite [H]

COG id: COG0003

COG function: function code P; Oxyanion-translocating ATPase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arsA ATPase family [H]

Homologues:

Organism=Homo sapiens, GI50428938, Length=316, Percent_Identity=34.8101265822785, Blast_Score=171, Evalue=9e-43,
Organism=Caenorhabditis elegans, GI17557003, Length=280, Percent_Identity=33.5714285714286, Blast_Score=150, Evalue=8e-37,
Organism=Saccharomyces cerevisiae, GI6320103, Length=327, Percent_Identity=31.1926605504587, Blast_Score=157, Evalue=3e-39,
Organism=Drosophila melanogaster, GI24586297, Length=319, Percent_Identity=32.6018808777429, Blast_Score=167, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003348 [H]

Pfam domain/function: NA

EC number: =3.6.3.16 [H]

Molecular weight: Translated: 38769; Mature: 38769

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
6.7 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
6.7 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLSKIKESLKGITSKKLEKENGTKYIMFGGKGGVGKTTMSAATGIYCAEQGLKTVVVST
CCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEEC
DPAHSLKDSFEQSFGHEPTKVNGMENLYVVEIDPEVAMSEYKEKLKSQMDENPMMGGMLE
CCHHHHHHHHHHHHCCCCCEECCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCHHH
DQLEMASLSPGTDESAAFDVFLKYMDNNEFDVVVFDTAPTGHTLRFLGLPELMDKYMTKM
HHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCEEEECCCHHHHHHHHHHH
IKFKKQMSGFMNMMKKVMPFGGKGEDVDYDKALEEMEEMKARITKARGILANPERTAFRL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEE
VVIPEEMSILESERAMESLNKFKIPVDSVVVNQIIPEDVECDFCRARRSLQEKRLELVKE
EEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
KFGDKVIANLELLRTEAKGLDVLKDIAHKLYGEAKSEEEKEVIVA
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MVLSKIKESLKGITSKKLEKENGTKYIMFGGKGGVGKTTMSAATGIYCAEQGLKTVVVST
CCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEEC
DPAHSLKDSFEQSFGHEPTKVNGMENLYVVEIDPEVAMSEYKEKLKSQMDENPMMGGMLE
CCHHHHHHHHHHHHCCCCCEECCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCHHH
DQLEMASLSPGTDESAAFDVFLKYMDNNEFDVVVFDTAPTGHTLRFLGLPELMDKYMTKM
HHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCEEEECCCHHHHHHHHHHH
IKFKKQMSGFMNMMKKVMPFGGKGEDVDYDKALEEMEEMKARITKARGILANPERTAFRL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEE
VVIPEEMSILESERAMESLNKFKIPVDSVVVNQIIPEDVECDFCRARRSLQEKRLELVKE
EEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
KFGDKVIANLELLRTEAKGLDVLKDIAHKLYGEAKSEEEKEVIVA
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]