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The map label for this gene is fdhB [H]

Identifier: 45357702

GI number: 45357702

Start: 147092

End: 148219

Strand: Direct

Name: fdhB [H]

Synonym: MMP0139

Alternate gene names: 45357702

Gene position: 147092-148219 (Clockwise)

Preceding gene: 45357701

Following gene: 45357711

Centisome position: 8.85

GC content: 36.26

Gene sequence:

>1128_bases
ATGAGCTATTATTTAGTTCAGTCAACGGACGAAGATATTTTAAAGCATGCGGAATGTGGTGGGGCAGTTACTGCATTTTT
CAAGTACCTTCTTGATAAAAAACTGGTTGATGGAGTTTTAGCACTTAAAAAAGGAGAAGACGTTTATGACGGACTTCCTT
ATTTGGTTAACGACTCAAAAGAACTGGTAGAAACTTGCGGTTCACTTCACTGCGCTCCAACAATGTTTGGAAACATGATA
AGCAAGCACTTGAAAGATATGAATCTTGCAGTATCTGTAAAGCCATGTGATGCAATGGCGATAGTAGAGCTTGAAAAAAG
ACATCAAATTGATAAAGATAAATTATATACAATTGGATTGAATTGTGGTGGAACAGTTCCCCCACAAACTGCAAAAAAGA
TGATTGAACTCTTTTACGATGTAGATCCAGAAGATGTAATCAAAGAAGAAATCGATAAAGGAAAATTCATAATTGAATTA
AAAGATGGAAGTGAAAAATCCGTTAAAATCGATGAACTCGAAGAAGAAGGATACGGAAGAAGAACTAACTGTCAAAGATG
TGAATTGAAAGTTCCAAGAAATTCAGATCTTGCCTGCGGAAACTGGGGTACTGAAAAAGGATGGACTTTTGTAGAAGTTG
GTTCCGAAAAAGGAGAAGAATTACTTAAAAACGCACAAAAAGAAGGATACATAAATGTTAAAGCACCTTCTGAAAAAGCG
CTTGAAATCAGGGGAAAAATCGAGAAATCAATGATTAATCTCGGTAAAAAATTCCAAAAAGAACAATTGGACGAAAAATA
TCCTGAACCTGAAAAATGGGATGAATACTGGAGCAGATGCATAAAATGCTACGGTTGTAGGGATGTATGTCCAATATGTT
TCTGTAAAGAATGTGCTTTAGGTGAAGACTATCTTGATAAAGGAACAATACCTCCTGATCCAATAATGTTCCAGGGAATC
AGGCTTTCACACATGAGTTTCAGCTGTATAAACTGTGGACAGTGCGAAGACGTATGTCCTGTAGAAATTCCACTAGCAAA
AATATATCACAGAGCGCAACTGAAAATCAGGGAAACTACTGGATTTGTTCCAGGAATTGACGACAGTATGCCGTTTTTAT
ATAAATAA

Upstream 100 bases:

>100_bases
TAACAAATTCCGCGTATGACCCAGTATCAAAAACCGCAGAACTAAAAATATGTGCCGTTAAAGTTGAAAAAATTTAATAA
TTATTTTTGAGGTGATTTAA

Downstream 100 bases:

>100_bases
TGATAGTTACAGGTATGCCTAATTTCTTTTTTCTTTTTTTAAAATAAATTAATTAGAATTTAAAAGATATCCTATAGCTT
GACCAAATGAAATTCCGCCG

Product: formate dehydrogenase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MSYYLVQSTDEDILKHAECGGAVTAFFKYLLDKKLVDGVLALKKGEDVYDGLPYLVNDSKELVETCGSLHCAPTMFGNMI
SKHLKDMNLAVSVKPCDAMAIVELEKRHQIDKDKLYTIGLNCGGTVPPQTAKKMIELFYDVDPEDVIKEEIDKGKFIIEL
KDGSEKSVKIDELEEEGYGRRTNCQRCELKVPRNSDLACGNWGTEKGWTFVEVGSEKGEELLKNAQKEGYINVKAPSEKA
LEIRGKIEKSMINLGKKFQKEQLDEKYPEPEKWDEYWSRCIKCYGCRDVCPICFCKECALGEDYLDKGTIPPDPIMFQGI
RLSHMSFSCINCGQCEDVCPVEIPLAKIYHRAQLKIRETTGFVPGIDDSMPFLYK

Sequences:

>Translated_375_residues
MSYYLVQSTDEDILKHAECGGAVTAFFKYLLDKKLVDGVLALKKGEDVYDGLPYLVNDSKELVETCGSLHCAPTMFGNMI
SKHLKDMNLAVSVKPCDAMAIVELEKRHQIDKDKLYTIGLNCGGTVPPQTAKKMIELFYDVDPEDVIKEEIDKGKFIIEL
KDGSEKSVKIDELEEEGYGRRTNCQRCELKVPRNSDLACGNWGTEKGWTFVEVGSEKGEELLKNAQKEGYINVKAPSEKA
LEIRGKIEKSMINLGKKFQKEQLDEKYPEPEKWDEYWSRCIKCYGCRDVCPICFCKECALGEDYLDKGTIPPDPIMFQGI
RLSHMSFSCINCGQCEDVCPVEIPLAKIYHRAQLKIRETTGFVPGIDDSMPFLYK
>Mature_374_residues
SYYLVQSTDEDILKHAECGGAVTAFFKYLLDKKLVDGVLALKKGEDVYDGLPYLVNDSKELVETCGSLHCAPTMFGNMIS
KHLKDMNLAVSVKPCDAMAIVELEKRHQIDKDKLYTIGLNCGGTVPPQTAKKMIELFYDVDPEDVIKEEIDKGKFIIELK
DGSEKSVKIDELEEEGYGRRTNCQRCELKVPRNSDLACGNWGTEKGWTFVEVGSEKGEELLKNAQKEGYINVKAPSEKAL
EIRGKIEKSMINLGKKFQKEQLDEKYPEPEKWDEYWSRCIKCYGCRDVCPICFCKECALGEDYLDKGTIPPDPIMFQGIR
LSHMSFSCINCGQCEDVCPVEIPLAKIYHRAQLKIRETTGFVPGIDDSMPFLYK

Specific function: Catalyzes the oxidation of formate [H]

COG id: COG1035

COG function: function code C; Coenzyme F420-reducing hydrogenase, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR007516
- InterPro:   IPR007525
- InterPro:   IPR012285
- InterPro:   IPR009051 [H]

Pfam domain/function: PF04432 FrhB_FdhB_C; PF04422 FrhB_FdhB_N [H]

EC number: =1.2.1.2 [H]

Molecular weight: Translated: 42431; Mature: 42300

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
7.7 %Cys+Met (Translated Protein)
5.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYYLVQSTDEDILKHAECGGAVTAFFKYLLDKKLVDGVLALKKGEDVYDGLPYLVNDSK
CCEEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCEEECCCH
ELVETCGSLHCAPTMFGNMISKHLKDMNLAVSVKPCDAMAIVELEKRHQIDKDKLYTIGL
HHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCHHEEEHHHHCCCCCCEEEEEE
NCGGTVPPQTAKKMIELFYDVDPEDVIKEEIDKGKFIIELKDGSEKSVKIDELEEEGYGR
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEECCCCCCCEEHHHHHHCCCCC
RTNCQRCELKVPRNSDLACGNWGTEKGWTFVEVGSEKGEELLKNAQKEGYINVKAPSEKA
CCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCEEEEECCCCHH
LEIRGKIEKSMINLGKKFQKEQLDEKYPEPEKWDEYWSRCIKCYGCRDVCPICFCKECAL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCC
GEDYLDKGTIPPDPIMFQGIRLSHMSFSCINCGQCEDVCPVEIPLAKIYHRAQLKIRETT
CCHHHCCCCCCCCCCEECCEEEECCEEECCCCCCCCCCCCCCCCHHHHHHHHHEEEECCC
GFVPGIDDSMPFLYK
CCCCCCCCCCCCCCC
>Mature Secondary Structure 
SYYLVQSTDEDILKHAECGGAVTAFFKYLLDKKLVDGVLALKKGEDVYDGLPYLVNDSK
CEEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCEEECCCH
ELVETCGSLHCAPTMFGNMISKHLKDMNLAVSVKPCDAMAIVELEKRHQIDKDKLYTIGL
HHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCHHEEEHHHHCCCCCCEEEEEE
NCGGTVPPQTAKKMIELFYDVDPEDVIKEEIDKGKFIIELKDGSEKSVKIDELEEEGYGR
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEECCCCCCCEEHHHHHHCCCCC
RTNCQRCELKVPRNSDLACGNWGTEKGWTFVEVGSEKGEELLKNAQKEGYINVKAPSEKA
CCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCEEEEECCCCHH
LEIRGKIEKSMINLGKKFQKEQLDEKYPEPEKWDEYWSRCIKCYGCRDVCPICFCKECAL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCC
GEDYLDKGTIPPDPIMFQGIRLSHMSFSCINCGQCEDVCPVEIPLAKIYHRAQLKIRETT
CCHHHCCCCCCCCCCEECCEEEECCEEECCCCCCCCCCCCCCCCHHHHHHHHHEEEECCC
GFVPGIDDSMPFLYK
CCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]