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The map label for this gene is mptA [H]

Identifier: 45357597

GI number: 45357597

Start: 51767

End: 52714

Strand: Direct

Name: mptA [H]

Synonym: MMP0034

Alternate gene names: 45357597

Gene position: 51767-52714 (Clockwise)

Preceding gene: 45357596

Following gene: 45357598

Centisome position: 3.12

GC content: 34.92

Gene sequence:

>948_bases
ATGCAATGCAATGACGTTCAGGCAACAGAACCTGATATTAAGGTTTCATTAACCCGGGTTGGCGTAACAAACCTAAAAAA
ACTTGTAAAATTAAAAAGAAAAAATAAAAGAGACATCGTTCTTCTCCCCACCTTCGAAGTTTTTGTGGATCTTCCAAGTT
CGCAAAAAGGAATTCATATGTCAAGAAGCCCCGAAGTAATCGAAGAAGTAGTTGAAAACATACTTTTAGAAAAGGAAATT
TATGGTGTTGAAGATTTATCTGTTGAAATAGTTATGAAACTCTTCGAAAAACACGAATATGCGACAAGAGCCGAAGTAAT
GCTTTACAGCGATTACATGATGGAAGAAAAATCCCCTGTAACAAAAAAAGATTCCCAGGAGATTGGAAAGATAATTGCAA
GAGCATACGGTGTAAAAGACAGCAATGGAAAAATAGATGTAAAAAAGATGGTTGGTGCAGAAGTTGTTGGAATTACGGCA
TGCCCCTGTGCACAAAACATGTTAAAAGAAAATGCAGTTGTTAGTTTAACTGAAAAAGGATTTTCAAGCGAAGACATTGA
AAAAATTCTTGATTCAGTTACCATTGCAACACACAACCAAAGGGGAATTGGAACGGTTATGATAGAAGTTCCAAATGGAT
ATACTGTTGGAATTTCAAAAATAATCAAAATAATTAAAGATTCAATGAGTGGGGAAGTTTACGAACTTTTGAAGAGAAGT
GACGAAGCTTTTGTTGTAGAGGCAGCTCACAAAAATCCAAAATTTGTTGAAGACTGTGCAAGAGAGATGATAAAAAGAGT
TGTGGATGTTTTTGATTATCTTCCTGAAGATACACAAGTTCTTGTAAGGCAGGTAAATAAAGAGAGTATTCACAGACACG
ATGCTTTTGCAGAACGAAATTCTACAATAAGGGAACTAAGGGACGAACTTAAAACTTTAACAAATTAA

Upstream 100 bases:

>100_bases
AAAGAGATGGATATAATGTATACTACACTTTATCCAAGGAATTAAAGGACGTTTTGATAACAAAAGAAGATATTTCGTAA
ATTATTTCAGGTGTTTTTTG

Downstream 100 bases:

>100_bases
TTTTAATTTATTTTTTAGTGGTTTTATGAAAGCTCTCGTTGTTGGGGCATGTACGCGCCCTGTTGTAAATTCTTTAAAAA
AATTAAATTTTGAAGTTTAT

Product: GTP cyclohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MQCNDVQATEPDIKVSLTRVGVTNLKKLVKLKRKNKRDIVLLPTFEVFVDLPSSQKGIHMSRSPEVIEEVVENILLEKEI
YGVEDLSVEIVMKLFEKHEYATRAEVMLYSDYMMEEKSPVTKKDSQEIGKIIARAYGVKDSNGKIDVKKMVGAEVVGITA
CPCAQNMLKENAVVSLTEKGFSSEDIEKILDSVTIATHNQRGIGTVMIEVPNGYTVGISKIIKIIKDSMSGEVYELLKRS
DEAFVVEAAHKNPKFVEDCAREMIKRVVDVFDYLPEDTQVLVRQVNKESIHRHDAFAERNSTIRELRDELKTLTN

Sequences:

>Translated_315_residues
MQCNDVQATEPDIKVSLTRVGVTNLKKLVKLKRKNKRDIVLLPTFEVFVDLPSSQKGIHMSRSPEVIEEVVENILLEKEI
YGVEDLSVEIVMKLFEKHEYATRAEVMLYSDYMMEEKSPVTKKDSQEIGKIIARAYGVKDSNGKIDVKKMVGAEVVGITA
CPCAQNMLKENAVVSLTEKGFSSEDIEKILDSVTIATHNQRGIGTVMIEVPNGYTVGISKIIKIIKDSMSGEVYELLKRS
DEAFVVEAAHKNPKFVEDCAREMIKRVVDVFDYLPEDTQVLVRQVNKESIHRHDAFAERNSTIRELRDELKTLTN
>Mature_315_residues
MQCNDVQATEPDIKVSLTRVGVTNLKKLVKLKRKNKRDIVLLPTFEVFVDLPSSQKGIHMSRSPEVIEEVVENILLEKEI
YGVEDLSVEIVMKLFEKHEYATRAEVMLYSDYMMEEKSPVTKKDSQEIGKIIARAYGVKDSNGKIDVKKMVGAEVVGITA
CPCAQNMLKENAVVSLTEKGFSSEDIEKILDSVTIATHNQRGIGTVMIEVPNGYTVGISKIIKIIKDSMSGEVYELLKRS
DEAFVVEAAHKNPKFVEDCAREMIKRVVDVFDYLPEDTQVLVRQVNKESIHRHDAFAERNSTIRELRDELKTLTN

Specific function: Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin [H]

COG id: COG1469

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase IV family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003801
- InterPro:   IPR022840
- InterPro:   IPR002042 [H]

Pfam domain/function: PF02649 DUF198 [H]

EC number: NA

Molecular weight: Translated: 35608; Mature: 35608

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQCNDVQATEPDIKVSLTRVGVTNLKKLVKLKRKNKRDIVLLPTFEVFVDLPSSQKGIHM
CCCCCCCCCCCCCEEEEEHHCHHHHHHHHHHHHCCCCCEEEEEHHHHEEECCCCCCCCCC
SRSPEVIEEVVENILLEKEIYGVEDLSVEIVMKLFEKHEYATRAEVMLYSDYMMEEKSPV
CCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHCCCCC
TKKDSQEIGKIIARAYGVKDSNGKIDVKKMVGAEVVGITACPCAQNMLKENAVVSLTEKG
CCCHHHHHHHHHHHHHCCCCCCCCEEHHHHHCCHHEEEEECHHHHHHHHCCCEEEECCCC
FSSEDIEKILDSVTIATHNQRGIGTVMIEVPNGYTVGISKIIKIIKDSMSGEVYELLKRS
CCHHHHHHHHHHHEEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHCC
DEAFVVEAAHKNPKFVEDCAREMIKRVVDVFDYLPEDTQVLVRQVNKESIHRHDAFAERN
CCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
STIRELRDELKTLTN
HHHHHHHHHHHHHCC
>Mature Secondary Structure
MQCNDVQATEPDIKVSLTRVGVTNLKKLVKLKRKNKRDIVLLPTFEVFVDLPSSQKGIHM
CCCCCCCCCCCCCEEEEEHHCHHHHHHHHHHHHCCCCCEEEEEHHHHEEECCCCCCCCCC
SRSPEVIEEVVENILLEKEIYGVEDLSVEIVMKLFEKHEYATRAEVMLYSDYMMEEKSPV
CCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHCCCCC
TKKDSQEIGKIIARAYGVKDSNGKIDVKKMVGAEVVGITACPCAQNMLKENAVVSLTEKG
CCCHHHHHHHHHHHHHCCCCCCCCEEHHHHHCCHHEEEEECHHHHHHHHCCCEEEECCCC
FSSEDIEKILDSVTIATHNQRGIGTVMIEVPNGYTVGISKIIKIIKDSMSGEVYELLKRS
CCHHHHHHHHHHHEEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHCC
DEAFVVEAAHKNPKFVEDCAREMIKRVVDVFDYLPEDTQVLVRQVNKESIHRHDAFAERN
CCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
STIRELRDELKTLTN
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA