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The map label for this gene is kup

Identifier: 42523474

GI number: 42523474

Start: 1912073

End: 1914082

Strand: Direct

Name: kup

Synonym: Bd1998

Alternate gene names: 42523474

Gene position: 1912073-1914082 (Clockwise)

Preceding gene: 42523473

Following gene: 42523477

Centisome position: 50.54

GC content: 50.85

Gene sequence:

>2010_bases
ATGTGGGCAAGATGCGTCAATCTTGCATGGGGACTGCTGACATCACGGATGAACTTAACTAGACTAAAACCTTGTTTCGA
CAACTTAGACGGGGTTTTTGGTATCGAAAATTCAGGCCATCACAAAAATAGTTCCAATGTTTTAATGCTCGCATTAGGCG
CCCTTGGTGTGGTGTTCGGCGATATCGGTACAAGTCCTCTGTATGCATTGAAAGAGTGTTTCGGTCACTATGGTTTGGCG
CCCACGCCAGAAAACGTGATCGGAATATTGTCTTTGATCTTCTGGACGCTGGTTCTTGCCATCTGTATCAAGTACATGGC
GTTTGTCTTAAGAGCAGACAATAAAGGTGAGGGGGGGATTCTTTCCCTGATGGCTCTGGCTGTGCGCAGTCAGCAGTCCA
AGGATGTTTCGCGCCGGCGCTGGACCATGACGATCATCGGTCTGTTTGGAGCGGCCTTGCTTTATGGTGACGGTATTATC
ACTCCGGCGATCTCAGTGCTTTCGGCGATGGAAGGTCTCACCTTGGTCGCTCCACAGTTTAGTCCTTACATTATTCCTCT
GACTATTTTTGTGATGAACGCCCTCTTTCTGATGCAAAAGTACGGCACGGCTCGTATCGGCGTTATCTTCGGTCCGATTC
TTCTGATTTGGTTCACTGTTCTGGGCTTGTTGGGTATTCGCGGGATGGCGAAAAACCTGCATGTCTTTGAAGCTCTGCTG
CCACATCATGGGATTGAGTTCCTGATGAACAATGGGATGGCGGGTTTCCTGGTGCTGGGGTCGGTGTTTCTGGTTGTGAC
CGGAGGCGAGGCCTTGTATGCGGACATGGGGCATTTTGGTAAACGACCAATTCGTCTGGCGTGGTTCTTTGTTGCTTTAC
CAGCCTTGGTATTAAACTACTTCGGTCAAGGGGCTTTGCTGCTGAACAATCCTGAGGCTGTATCCAATCCTTTCTATATG
CTGGCGCCAAAATGGGCTCTGCTTCCGATGGTCATGCTTTCTACGATGGCCACGGTTATCGCATCCCAGGCGTTGATCAC
CGGGGTGTTTTCCATCACTCGTCAGGCAATCCAACTGGGTTTCTGTCCGCGCGTGAACATCATTCACACTTCCAGTCAGG
AGATCGGTCAGATCTACATTCCAATTGTGAACTGGTCCATGTTCATCGGTGTGATCTGGCTGGTGTTGACATTTAAGACC
TCCAGCAATCTGGCGGCAGCCTATGGAATTGCTGTGACTGGTGCGACGATGATCACCACAATCCTGGCGTTTGAAGTGGC
TCGTCAAAAATGGAAATGGAGTCTGCTGAAGTCTTCGGCCATTTTTGGCAGCTTCCTGGTGATGGATCTGGCCTTCTTTG
GTGCCAACGTTCATAAGATCCCGCATGGGGGCTGGGTGCCGTTGGTTATTGGGGCGATCATTTACCTGTTGATGACGACC
TGGCAAAAGGGCCGTCAGATTTTGTTCCGACGTCTTAAAGAACGCTCCATGCCTATTGAAGACTTCTGCCAGAAGCTTCT
GCGTGAGCCTCCACTGCGAGCTCCGGGCACGGCGATATATATGGCCGGTGACCCTTGGGGTGTTCCAGCACCGCTGCTGC
ATAATATGAAGCACAACAAGGTTCTGCATCAGCGCGTGGCGATCCTGACGATTCAGACCAAAGAAGTGCCGTTTGTTTCC
AAGCGCGATCGCATTTCCATTCAGGAAGTGATTCCGAATATCTACCGCATTATCGCCAACTATGGCTTTATGGAAATCCC
CAAGATGAAACATATTCTTGAGGCCTGCCGTCAGCGCGATATCAACTTTAACGTGAATGAAACCACGTTCGTGCTGGGAC
GCGAAACCATCATCGCGGAAAAAGGACCGAATCGTCCGGGCGAAGCAGGGATGGCACACTGGCGTGAACGTCTGTTTGCC
ATCATGTCCAAGAATGCCCAGCGACCGACGGCGTTCTTCCGCATCCCGCCGAATCAGGTGATCGAAGTGGGAATTCAGGT
CGAGATCTAG

Upstream 100 bases:

>100_bases
AAGAGGGCTGCCAAAAACCATTTCGAGCGAAAAAGTGCATTCCGTGCCATAGATCTATGGTCTCAAAGAGCCTAAAATAA
AGGCAACTGAACTTCGTGTA

Downstream 100 bases:

>100_bases
TCATCATGGAGCAGGCGAACAACCTGCTCCCGGACATTGATGCCATCCTTGTATCCAATTTCTATCAGATCTGCCGAATA
GGATTTTTCAAACAACAGAA

Product: KUP system, potassium uptake transmembrane protein

Products: K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 669; Mature: 669

Protein sequence:

>669_residues
MWARCVNLAWGLLTSRMNLTRLKPCFDNLDGVFGIENSGHHKNSSNVLMLALGALGVVFGDIGTSPLYALKECFGHYGLA
PTPENVIGILSLIFWTLVLAICIKYMAFVLRADNKGEGGILSLMALAVRSQQSKDVSRRRWTMTIIGLFGAALLYGDGII
TPAISVLSAMEGLTLVAPQFSPYIIPLTIFVMNALFLMQKYGTARIGVIFGPILLIWFTVLGLLGIRGMAKNLHVFEALL
PHHGIEFLMNNGMAGFLVLGSVFLVVTGGEALYADMGHFGKRPIRLAWFFVALPALVLNYFGQGALLLNNPEAVSNPFYM
LAPKWALLPMVMLSTMATVIASQALITGVFSITRQAIQLGFCPRVNIIHTSSQEIGQIYIPIVNWSMFIGVIWLVLTFKT
SSNLAAAYGIAVTGATMITTILAFEVARQKWKWSLLKSSAIFGSFLVMDLAFFGANVHKIPHGGWVPLVIGAIIYLLMTT
WQKGRQILFRRLKERSMPIEDFCQKLLREPPLRAPGTAIYMAGDPWGVPAPLLHNMKHNKVLHQRVAILTIQTKEVPFVS
KRDRISIQEVIPNIYRIIANYGFMEIPKMKHILEACRQRDINFNVNETTFVLGRETIIAEKGPNRPGEAGMAHWRERLFA
IMSKNAQRPTAFFRIPPNQVIEVGIQVEI

Sequences:

>Translated_669_residues
MWARCVNLAWGLLTSRMNLTRLKPCFDNLDGVFGIENSGHHKNSSNVLMLALGALGVVFGDIGTSPLYALKECFGHYGLA
PTPENVIGILSLIFWTLVLAICIKYMAFVLRADNKGEGGILSLMALAVRSQQSKDVSRRRWTMTIIGLFGAALLYGDGII
TPAISVLSAMEGLTLVAPQFSPYIIPLTIFVMNALFLMQKYGTARIGVIFGPILLIWFTVLGLLGIRGMAKNLHVFEALL
PHHGIEFLMNNGMAGFLVLGSVFLVVTGGEALYADMGHFGKRPIRLAWFFVALPALVLNYFGQGALLLNNPEAVSNPFYM
LAPKWALLPMVMLSTMATVIASQALITGVFSITRQAIQLGFCPRVNIIHTSSQEIGQIYIPIVNWSMFIGVIWLVLTFKT
SSNLAAAYGIAVTGATMITTILAFEVARQKWKWSLLKSSAIFGSFLVMDLAFFGANVHKIPHGGWVPLVIGAIIYLLMTT
WQKGRQILFRRLKERSMPIEDFCQKLLREPPLRAPGTAIYMAGDPWGVPAPLLHNMKHNKVLHQRVAILTIQTKEVPFVS
KRDRISIQEVIPNIYRIIANYGFMEIPKMKHILEACRQRDINFNVNETTFVLGRETIIAEKGPNRPGEAGMAHWRERLFA
IMSKNAQRPTAFFRIPPNQVIEVGIQVEI
>Mature_669_residues
MWARCVNLAWGLLTSRMNLTRLKPCFDNLDGVFGIENSGHHKNSSNVLMLALGALGVVFGDIGTSPLYALKECFGHYGLA
PTPENVIGILSLIFWTLVLAICIKYMAFVLRADNKGEGGILSLMALAVRSQQSKDVSRRRWTMTIIGLFGAALLYGDGII
TPAISVLSAMEGLTLVAPQFSPYIIPLTIFVMNALFLMQKYGTARIGVIFGPILLIWFTVLGLLGIRGMAKNLHVFEALL
PHHGIEFLMNNGMAGFLVLGSVFLVVTGGEALYADMGHFGKRPIRLAWFFVALPALVLNYFGQGALLLNNPEAVSNPFYM
LAPKWALLPMVMLSTMATVIASQALITGVFSITRQAIQLGFCPRVNIIHTSSQEIGQIYIPIVNWSMFIGVIWLVLTFKT
SSNLAAAYGIAVTGATMITTILAFEVARQKWKWSLLKSSAIFGSFLVMDLAFFGANVHKIPHGGWVPLVIGAIIYLLMTT
WQKGRQILFRRLKERSMPIEDFCQKLLREPPLRAPGTAIYMAGDPWGVPAPLLHNMKHNKVLHQRVAILTIQTKEVPFVS
KRDRISIQEVIPNIYRIIANYGFMEIPKMKHILEACRQRDINFNVNETTFVLGRETIIAEKGPNRPGEAGMAHWRERLFA
IMSKNAQRPTAFFRIPPNQVIEVGIQVEI

Specific function: Transport of potassium into the cell

COG id: COG3158

COG function: function code P; K+ transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAK/KUP transporter (TC 2.A.72) family

Homologues:

Organism=Escherichia coli, GI48994960, Length=629, Percent_Identity=48.0127186009539, Blast_Score=623, Evalue=1e-179,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KUP_BDEBA (Q6MLL0)

Other databases:

- EMBL:   BX842651
- RefSeq:   NP_968854.1
- GeneID:   2734710
- GenomeReviews:   BX842601_GR
- KEGG:   bba:Bd1998
- NMPDR:   fig|264462.1.peg.1825
- HOGENOM:   HBG351154
- OMA:   NGIESAN
- PhylomeDB:   Q6MLL0
- BioCyc:   BBAC264462:BD1998-MONOMER
- HAMAP:   MF_01522
- InterPro:   IPR003855
- InterPro:   IPR023051

Pfam domain/function: PF02705 K_trans

EC number: NA

Molecular weight: Translated: 74255; Mature: 74255

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xd74dbd0)-; HASH(0xf3881ec)-; HASH(0xde247fc)-; HASH(0xcde9c48)-; HASH(0xf7a477c)-; HASH(0xf869584)-; HASH(0xf00f108)-; HASH(0xf1a197c)-; HASH(0xf984058)-; HASH(0xf75867c)-; HASH(0xdfb5bdc)-; HASH(0xfaa0d10)-;

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWARCVNLAWGLLTSRMNLTRLKPCFDNLDGVFGIENSGHHKNSSNVLMLALGALGVVFG
CCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEECCCCCCCCCCCCEEEHHHHHHHHHHH
DIGTSPLYALKECFGHYGLAPTPENVIGILSLIFWTLVLAICIKYMAFVLRADNKGEGGI
CCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
LSLMALAVRSQQSKDVSRRRWTMTIIGLFGAALLYGDGIITPAISVLSAMEGLTLVAPQF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEECCCC
SPYIIPLTIFVMNALFLMQKYGTARIGVIFGPILLIWFTVLGLLGIRGMAKNLHVFEALL
CCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PHHGIEFLMNNGMAGFLVLGSVFLVVTGGEALYADMGHFGKRPIRLAWFFVALPALVLNY
CCCCHHHHHCCCCHHHHHHHHHHEEEECCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
FGQGALLLNNPEAVSNPFYMLAPKWALLPMVMLSTMATVIASQALITGVFSITRQAIQLG
CCCCEEEECCCHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
FCPRVNIIHTSSQEIGQIYIPIVNWSMFIGVIWLVLTFKTSSNLAAAYGIAVTGATMITT
CCCCCEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
ILAFEVARQKWKWSLLKSSAIFGSFLVMDLAFFGANVHKIPHGGWVPLVIGAIIYLLMTT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHH
WQKGRQILFRRLKERSMPIEDFCQKLLREPPLRAPGTAIYMAGDPWGVPAPLLHNMKHNK
HHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCHHHHHCCHHHH
VLHQRVAILTIQTKEVPFVSKRDRISIQEVIPNIYRIIANYGFMEIPKMKHILEACRQRD
HHHHHEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCC
INFNVNETTFVLGRETIIAEKGPNRPGEAGMAHWRERLFAIMSKNAQRPTAFFRIPPNQV
CCCCCCCEEEEEECCEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHH
IEVGIQVEI
EEEEEEEEH
>Mature Secondary Structure
MWARCVNLAWGLLTSRMNLTRLKPCFDNLDGVFGIENSGHHKNSSNVLMLALGALGVVFG
CCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEECCCCCCCCCCCCEEEHHHHHHHHHHH
DIGTSPLYALKECFGHYGLAPTPENVIGILSLIFWTLVLAICIKYMAFVLRADNKGEGGI
CCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
LSLMALAVRSQQSKDVSRRRWTMTIIGLFGAALLYGDGIITPAISVLSAMEGLTLVAPQF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEECCCC
SPYIIPLTIFVMNALFLMQKYGTARIGVIFGPILLIWFTVLGLLGIRGMAKNLHVFEALL
CCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PHHGIEFLMNNGMAGFLVLGSVFLVVTGGEALYADMGHFGKRPIRLAWFFVALPALVLNY
CCCCHHHHHCCCCHHHHHHHHHHEEEECCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
FGQGALLLNNPEAVSNPFYMLAPKWALLPMVMLSTMATVIASQALITGVFSITRQAIQLG
CCCCEEEECCCHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
FCPRVNIIHTSSQEIGQIYIPIVNWSMFIGVIWLVLTFKTSSNLAAAYGIAVTGATMITT
CCCCCEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
ILAFEVARQKWKWSLLKSSAIFGSFLVMDLAFFGANVHKIPHGGWVPLVIGAIIYLLMTT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHH
WQKGRQILFRRLKERSMPIEDFCQKLLREPPLRAPGTAIYMAGDPWGVPAPLLHNMKHNK
HHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCHHHHHCCHHHH
VLHQRVAILTIQTKEVPFVSKRDRISIQEVIPNIYRIIANYGFMEIPKMKHILEACRQRD
HHHHHEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCC
INFNVNETTFVLGRETIIAEKGPNRPGEAGMAHWRERLFAIMSKNAQRPTAFFRIPPNQV
CCCCCCCEEEEEECCEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHH
IEVGIQVEI
EEEEEEEEH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA