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The map label for this gene is yleA [C]

Identifier: 42523418

GI number: 42523418

Start: 1852919

End: 1854250

Strand: Direct

Name: yleA [C]

Synonym: Bd1940

Alternate gene names: 42523418

Gene position: 1852919-1854250 (Clockwise)

Preceding gene: 42523417

Following gene: 42523419

Centisome position: 48.98

GC content: 52.18

Gene sequence:

>1332_bases
ATGAAGTATCAGGTCCACACTTTCGGCTGTAAGGTGAACACTTATGACGCCGGCCTGATCCAGAAAAACCTGAACGCCAG
TGGCTTCATGCCGGTGGTGTCCGGCCAGAAAGACGCGCGCATTCACGTGCTGAATACCTGTGCCGTGACTGCGGAAGCCA
CGAAAGAGGCCGTTCGCTACATCCGTCGTTTGAAAGTGAAAGATCCTTTCTGCACGATCGTGGTGACAGGCTGTGCGGCG
CAAGTTGATACCGGGTCATTCTCGAGTCTTCCAGGGGCTGATCTTATTGTGGCCAATTCCCACAAAAGCAGTCTGCCGGA
TCTTTTGAACAAGCATTTCCGTGGTGAACTGACTGAAAAAGTCTTTAAATCCAACATCTTCAAAAAAGAAGATCTGGAAG
CCGGCGGTGGTATTGAAAAACAACACACCCGCACCTTCCTGAAAATTCAGGATGGCTGTAACAGCTTCTGCACCTATTGC
ATTATCCCGTATGCTCGTGGGAAAAGCCGTTCTATCCCGGTGGCGGATCTGGTGAATCGTATCAATGATCTGTATGCGGA
AGGCTCACGCGAAGTGGTGCTGACCGGTGTGCATATTGGGGATTACGAAGACCAGATCGGGGACCGCAAATACGTGATGG
AAGATCTGCTGGAAAATCTTCTGGCAAAAACCAAAATGCCACGTTTCCGTCTTTCAAGCCTTGAGCCGGTGGAAGTGTCT
GAGCGCCTGCTGGATCTTTATCAGGACTCACGTCTGTGTCCGCATTTCCACATGAGCATTCAAAGTGCCAACACGGATGT
GCTTTTCCATATGAAGCGCAAATACACGCAAGAAGACGTGCAAAAATCTCTGCGCGCGATTGCGGACCGTGTTCCAGGCA
GCTTTGTTGGGATGGACGTGATCACGGGTTTCCCAACTGAAACCGAAGAGCAATTCCAGGACACTTATAACTGCCTGAAG
GATCTGCCGTGGACCAAGCTGCACGTATTCCCGTACAGCGAACGTCAGGGCACTCGTGCGGCGGCCATGGATGTTTCTGT
GTATCCGCATGTGCGCGCGGAAAGAGCGGCCCGTCTGCGCGAACTGAGCATCGCCCGTTACACGGAGCAAGCCCAGAATC
AGATCGGCAGCACCAAGCGTGTACTGGTCCTGAAAAATGCCGCCAAAGGCGGACAGGGTCTCAGTCATGATTACTGGCCA
GTGGATATCGCAGGTGCGGAAAGCTTCCTGGATCACTGGGCAGGGCAGGAAGTTGATGTGAAAGTCACAGGCTATGATCA
TTCCAACAAACAACACATGGAAGGTCATCTGATCGGCGAGGTGCTCTCATGA

Upstream 100 bases:

>100_bases
TCAAATTGAAATTCACAGAGCCTCAGCGTGCGGTGACTCCGGGTCAGGCTGCCGTGTTCTATCGTGACAGACAGCTCGTG
GGGGGCGGATGGATCACTCT

Downstream 100 bases:

>100_bases
TCGATCAGGGGCGAAAGAGTCTGGAAGAGCGTGTAGGACATCAATTTAAAAACCCGGCACTGCTGGAAAGAGCGTTGACC
CACAAGAGTTTTGCCAACGA

Product: Fe-S oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MKYQVHTFGCKVNTYDAGLIQKNLNASGFMPVVSGQKDARIHVLNTCAVTAEATKEAVRYIRRLKVKDPFCTIVVTGCAA
QVDTGSFSSLPGADLIVANSHKSSLPDLLNKHFRGELTEKVFKSNIFKKEDLEAGGGIEKQHTRTFLKIQDGCNSFCTYC
IIPYARGKSRSIPVADLVNRINDLYAEGSREVVLTGVHIGDYEDQIGDRKYVMEDLLENLLAKTKMPRFRLSSLEPVEVS
ERLLDLYQDSRLCPHFHMSIQSANTDVLFHMKRKYTQEDVQKSLRAIADRVPGSFVGMDVITGFPTETEEQFQDTYNCLK
DLPWTKLHVFPYSERQGTRAAAMDVSVYPHVRAERAARLRELSIARYTEQAQNQIGSTKRVLVLKNAAKGGQGLSHDYWP
VDIAGAESFLDHWAGQEVDVKVTGYDHSNKQHMEGHLIGEVLS

Sequences:

>Translated_443_residues
MKYQVHTFGCKVNTYDAGLIQKNLNASGFMPVVSGQKDARIHVLNTCAVTAEATKEAVRYIRRLKVKDPFCTIVVTGCAA
QVDTGSFSSLPGADLIVANSHKSSLPDLLNKHFRGELTEKVFKSNIFKKEDLEAGGGIEKQHTRTFLKIQDGCNSFCTYC
IIPYARGKSRSIPVADLVNRINDLYAEGSREVVLTGVHIGDYEDQIGDRKYVMEDLLENLLAKTKMPRFRLSSLEPVEVS
ERLLDLYQDSRLCPHFHMSIQSANTDVLFHMKRKYTQEDVQKSLRAIADRVPGSFVGMDVITGFPTETEEQFQDTYNCLK
DLPWTKLHVFPYSERQGTRAAAMDVSVYPHVRAERAARLRELSIARYTEQAQNQIGSTKRVLVLKNAAKGGQGLSHDYWP
VDIAGAESFLDHWAGQEVDVKVTGYDHSNKQHMEGHLIGEVLS
>Mature_443_residues
MKYQVHTFGCKVNTYDAGLIQKNLNASGFMPVVSGQKDARIHVLNTCAVTAEATKEAVRYIRRLKVKDPFCTIVVTGCAA
QVDTGSFSSLPGADLIVANSHKSSLPDLLNKHFRGELTEKVFKSNIFKKEDLEAGGGIEKQHTRTFLKIQDGCNSFCTYC
IIPYARGKSRSIPVADLVNRINDLYAEGSREVVLTGVHIGDYEDQIGDRKYVMEDLLENLLAKTKMPRFRLSSLEPVEVS
ERLLDLYQDSRLCPHFHMSIQSANTDVLFHMKRKYTQEDVQKSLRAIADRVPGSFVGMDVITGFPTETEEQFQDTYNCLK
DLPWTKLHVFPYSERQGTRAAAMDVSVYPHVRAERAARLRELSIARYTEQAQNQIGSTKRVLVLKNAAKGGQGLSHDYWP
VDIAGAESFLDHWAGQEVDVKVTGYDHSNKQHMEGHLIGEVLS

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MTTase N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI93277076, Length=453, Percent_Identity=25.8278145695364, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI28872782, Length=414, Percent_Identity=25.3623188405797, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI28872784, Length=414, Percent_Identity=25.3623188405797, Blast_Score=127, Evalue=2e-29,
Organism=Escherichia coli, GI1786882, Length=428, Percent_Identity=27.5700934579439, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1787057, Length=417, Percent_Identity=25.8992805755396, Blast_Score=109, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17553146, Length=469, Percent_Identity=24.9466950959488, Blast_Score=121, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI71996771, Length=258, Percent_Identity=31.3953488372093, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI21356207, Length=435, Percent_Identity=25.2873563218391, Blast_Score=131, Evalue=9e-31,
Organism=Drosophila melanogaster, GI19922432, Length=399, Percent_Identity=27.8195488721804, Blast_Score=120, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006467
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 49708; Mature: 49708

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYQVHTFGCKVNTYDAGLIQKNLNASGFMPVVSGQKDARIHVLNTCAVTAEATKEAVRY
CCEEEEEEEEEEECCCCHHHHCCCCCCCCEEEECCCCCCEEEEEEEEEECHHHHHHHHHH
IRRLKVKDPFCTIVVTGCAAQVDTGSFSSLPGADLIVANSHKSSLPDLLNKHFRGELTEK
HHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHCHHHHHH
VFKSNIFKKEDLEAGGGIEKQHTRTFLKIQDGCNSFCTYCIIPYARGKSRSIPVADLVNR
HHHHCCCCCCCCCCCCCCCHHHHHHHEEECCCHHHHHHHHEEECCCCCCCCCCHHHHHHH
INDLYAEGSREVVLTGVHIGDYEDQIGDRKYVMEDLLENLLAKTKMPRFRLSSLEPVEVS
HHHHHHCCCCEEEEEEEEECCCHHHHCCHHHHHHHHHHHHHHHCCCCCHHCCCCCCHHHH
ERLLDLYQDSRLCPHFHMSIQSANTDVLFHMKRKYTQEDVQKSLRAIADRVPGSFVGMDV
HHHHHHHHCCCCCCHHEEEEECCCCEEEEHHHHHCCHHHHHHHHHHHHHHCCCCEECHHH
ITGFPTETEEQFQDTYNCLKDLPWTKLHVFPYSERQGTRAAAMDVSVYPHVRAERAARLR
HCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEEEEECCCHHHHHHHHHH
ELSIARYTEQAQNQIGSTKRVLVLKNAAKGGQGLSHDYWPVDIAGAESFLDHWAGQEVDV
HHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCEEECCHHHHHHHHCCCEEEE
KVTGYDHSNKQHMEGHLIGEVLS
EEECCCCCCCHHHCHHHHHHHCC
>Mature Secondary Structure
MKYQVHTFGCKVNTYDAGLIQKNLNASGFMPVVSGQKDARIHVLNTCAVTAEATKEAVRY
CCEEEEEEEEEEECCCCHHHHCCCCCCCCEEEECCCCCCEEEEEEEEEECHHHHHHHHHH
IRRLKVKDPFCTIVVTGCAAQVDTGSFSSLPGADLIVANSHKSSLPDLLNKHFRGELTEK
HHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHCHHHHHH
VFKSNIFKKEDLEAGGGIEKQHTRTFLKIQDGCNSFCTYCIIPYARGKSRSIPVADLVNR
HHHHCCCCCCCCCCCCCCCHHHHHHHEEECCCHHHHHHHHEEECCCCCCCCCCHHHHHHH
INDLYAEGSREVVLTGVHIGDYEDQIGDRKYVMEDLLENLLAKTKMPRFRLSSLEPVEVS
HHHHHHCCCCEEEEEEEEECCCHHHHCCHHHHHHHHHHHHHHHCCCCCHHCCCCCCHHHH
ERLLDLYQDSRLCPHFHMSIQSANTDVLFHMKRKYTQEDVQKSLRAIADRVPGSFVGMDV
HHHHHHHHCCCCCCHHEEEEECCCCEEEEHHHHHCCHHHHHHHHHHHHHHCCCCEECHHH
ITGFPTETEEQFQDTYNCLKDLPWTKLHVFPYSERQGTRAAAMDVSVYPHVRAERAARLR
HCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEEEEECCCHHHHHHHHHH
ELSIARYTEQAQNQIGSTKRVLVLKNAAKGGQGLSHDYWPVDIAGAESFLDHWAGQEVDV
HHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCEEECCHHHHHHHHCCCEEEE
KVTGYDHSNKQHMEGHLIGEVLS
EEECCCCCCCHHHCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]