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The map label for this gene is yflS [H]

Identifier: 42523367

GI number: 42523367

Start: 1807713

End: 1809179

Strand: Direct

Name: yflS [H]

Synonym: Bd1887

Alternate gene names: 42523367

Gene position: 1807713-1809179 (Clockwise)

Preceding gene: 42523366

Following gene: 42523371

Centisome position: 47.79

GC content: 54.19

Gene sequence:

>1467_bases
ATGAAGCTGCCTCATGTGAAGATTGTGCCGGCCGTTATCGCATTTTTTGTGACCTGTCTTTTTTGGTTCGTGATTTCCCC
GCCGGAAGGGGTCGACCTCAACGCCTGGCGTTTGCTGGGGATCTTCGTCGGCACCATCACAGCTATCATTGGTAAAGCGC
TTCCTATCGGTGGTGCTGCCATGATCGGGATCCTGCTGGTGGGTATCACTCAAGTGACCAGTCCCGGAAACCCGGGTAAA
GCCATGGGCGATGCACTCAGTGGGTATTCAAACACTCTGATCTGGCTGATTGGTATTTCGTTCTTTATTTCCCGCGCTTT
CATTAAGACCGGCCTGGGTTCCCGCGTGGCTTATTACTTTGTTCGCGCCATTGGGAAAAAGACTCTGGGGATCAGCTATG
GGCTGTCTTTTGCCGAGTTGGTGCTGTCGCCAGTCATGCCAAGCAACACCGCTCGCGGCGGTGGCGTGCTTTACCCAATC
AATCGCTCCATCTCAGAATCCATGGGATCACGTCCGGATGAGGCGACAAGGTTGAAGGTCGGCGCCTTCCTGACTTTGGT
GGCCTATCAGATCAACGTGATCACGTCTGCGATGTTCATCACGGCGACCGCGCCCAATCCTTTGGTGACGGCGGGGATTC
GTGACATTGCCAAGATCGATGTGTCGTGGGCGCAGTGGGCGATGGCGGCCTTTGTTCCGGGCTTGCTGGCGATTCTGATC
ATCCCGTGGGTGTTGTTTAAGCTTTATCCTCCTCAGATCAAAGAAACTCCGGATGCTGCTGGTTATGCCAATAAAAAATT
GCAGGAACTGGGGCCGCTCAGACTGGATGAAAAGATACTGATTGGCGTCTTCTTCCTGCTGCTGTTTATCTGGGCTGGGG
GCCCTGAGTTGTTGTCGTCAGATCCGCTGTTTAAGGTGGATGCAACCGCTGGAGCGTTTGTGGGGCTTGGGGTGCTTCTG
TTTAGCGGGGTCCTGACTTGGGATGACCTGCTGAAAGAAAAAGGCGCCTGGGACACGGTGACTTGGTTCTCGTCCCTGGT
GATGTTGGCGACGTTCCTGAACAAGTTGGGCGTGGTGGCCTGGTTCTCTAAAACTGTCGAATCCTCGATCGCGCACTGGG
GCCTGGGGTGGATGGAGGCGGCCGCTATTTTGGTTCTGCTTTATGTGTTCATCCATTACTTCTTTGCCAGCAACACGGCT
CATATTTCGGCGCTGTTTGCTTCGTTCTTTGGGGTCGGGGTGGCCTTGGGGGCTCCGCCATTGATGTTTGGTCTGTTTCT
GGGCTTTGCTTCCTCGTTGTGTGCCTCTTTAACTCACTACGGGACGGGGTCGGCTCCAGTGCTGTTTGGGTCTGGGTATG
TGACAATGGGAGAGTGGTGGAAGTGGGGCTTTGTGGTGACACTTCTTAATCTGCTGATTTTCGCTGGTGGTTGTGCTGTT
TGGTGGAAGGTTTTGGGGTATTGGTGA

Upstream 100 bases:

>100_bases
TTTTTGCCGATGAGCTTCAGGTGCAATGTGGTGAAAAACTACTTCCTCTGAGGGGGGCTTAAAGCATATCCTGTTTGTAA
ATTCCAAACCGGGGATATGA

Downstream 100 bases:

>100_bases
GTCTAAAAGCCTAAAACTTGGGCAACTTGCAAATCCTTTTATGACCTTCTGCGAAAACTGTTTTCAAAGCGGGGGAAAGC
GTACAAGATGGTTCTTCATT

Product: 2-oxoglutarate/malate translocator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 488; Mature: 488

Protein sequence:

>488_residues
MKLPHVKIVPAVIAFFVTCLFWFVISPPEGVDLNAWRLLGIFVGTITAIIGKALPIGGAAMIGILLVGITQVTSPGNPGK
AMGDALSGYSNTLIWLIGISFFISRAFIKTGLGSRVAYYFVRAIGKKTLGISYGLSFAELVLSPVMPSNTARGGGVLYPI
NRSISESMGSRPDEATRLKVGAFLTLVAYQINVITSAMFITATAPNPLVTAGIRDIAKIDVSWAQWAMAAFVPGLLAILI
IPWVLFKLYPPQIKETPDAAGYANKKLQELGPLRLDEKILIGVFFLLLFIWAGGPELLSSDPLFKVDATAGAFVGLGVLL
FSGVLTWDDLLKEKGAWDTVTWFSSLVMLATFLNKLGVVAWFSKTVESSIAHWGLGWMEAAAILVLLYVFIHYFFASNTA
HISALFASFFGVGVALGAPPLMFGLFLGFASSLCASLTHYGTGSAPVLFGSGYVTMGEWWKWGFVVTLLNLLIFAGGCAV
WWKVLGYW

Sequences:

>Translated_488_residues
MKLPHVKIVPAVIAFFVTCLFWFVISPPEGVDLNAWRLLGIFVGTITAIIGKALPIGGAAMIGILLVGITQVTSPGNPGK
AMGDALSGYSNTLIWLIGISFFISRAFIKTGLGSRVAYYFVRAIGKKTLGISYGLSFAELVLSPVMPSNTARGGGVLYPI
NRSISESMGSRPDEATRLKVGAFLTLVAYQINVITSAMFITATAPNPLVTAGIRDIAKIDVSWAQWAMAAFVPGLLAILI
IPWVLFKLYPPQIKETPDAAGYANKKLQELGPLRLDEKILIGVFFLLLFIWAGGPELLSSDPLFKVDATAGAFVGLGVLL
FSGVLTWDDLLKEKGAWDTVTWFSSLVMLATFLNKLGVVAWFSKTVESSIAHWGLGWMEAAAILVLLYVFIHYFFASNTA
HISALFASFFGVGVALGAPPLMFGLFLGFASSLCASLTHYGTGSAPVLFGSGYVTMGEWWKWGFVVTLLNLLIFAGGCAV
WWKVLGYW
>Mature_488_residues
MKLPHVKIVPAVIAFFVTCLFWFVISPPEGVDLNAWRLLGIFVGTITAIIGKALPIGGAAMIGILLVGITQVTSPGNPGK
AMGDALSGYSNTLIWLIGISFFISRAFIKTGLGSRVAYYFVRAIGKKTLGISYGLSFAELVLSPVMPSNTARGGGVLYPI
NRSISESMGSRPDEATRLKVGAFLTLVAYQINVITSAMFITATAPNPLVTAGIRDIAKIDVSWAQWAMAAFVPGLLAILI
IPWVLFKLYPPQIKETPDAAGYANKKLQELGPLRLDEKILIGVFFLLLFIWAGGPELLSSDPLFKVDATAGAFVGLGVLL
FSGVLTWDDLLKEKGAWDTVTWFSSLVMLATFLNKLGVVAWFSKTVESSIAHWGLGWMEAAAILVLLYVFIHYFFASNTA
HISALFASFFGVGVALGAPPLMFGLFLGFASSLCASLTHYGTGSAPVLFGSGYVTMGEWWKWGFVVTLLNLLIFAGGCAV
WWKVLGYW

Specific function: Might be a malate transporter [H]

COG id: COG0471

COG function: function code P; Di- and tricarboxylate transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SLC13A transporter (TC 2.A.47) family [H]

Homologues:

Organism=Escherichia coli, GI1786986, Length=487, Percent_Identity=35.1129363449692, Blast_Score=285, Evalue=6e-78,
Organism=Escherichia coli, GI1789444, Length=470, Percent_Identity=32.5531914893617, Blast_Score=253, Evalue=2e-68,
Organism=Escherichia coli, GI1786829, Length=480, Percent_Identity=28.9583333333333, Blast_Score=228, Evalue=1e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001898 [H]

Pfam domain/function: PF00939 Na_sulph_symp [H]

EC number: NA

Molecular weight: Translated: 52551; Mature: 52551

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLPHVKIVPAVIAFFVTCLFWFVISPPEGVDLNAWRLLGIFVGTITAIIGKALPIGGAA
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHH
MIGILLVGITQVTSPGNPGKAMGDALSGYSNTLIWLIGISFFISRAFIKTGLGSRVAYYF
HHHHHHHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
VRAIGKKTLGISYGLSFAELVLSPVMPSNTARGGGVLYPINRSISESMGSRPDEATRLKV
HHHHHHHHCCHHHCHHHHHHHHHCCCCCCCCCCCCEEEECCCHHHHHHCCCCCHHHHHHH
GAFLTLVAYQINVITSAMFITATAPNPLVTAGIRDIAKIDVSWAQWAMAAFVPGLLAILI
HHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IPWVLFKLYPPQIKETPDAAGYANKKLQELGPLRLDEKILIGVFFLLLFIWAGGPELLSS
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHCCC
DPLFKVDATAGAFVGLGVLLFSGVLTWDDLLKEKGAWDTVTWFSSLVMLATFLNKLGVVA
CCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
WFSKTVESSIAHWGLGWMEAAAILVLLYVFIHYFFASNTAHISALFASFFGVGVALGAPP
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHH
LMFGLFLGFASSLCASLTHYGTGSAPVLFGSGYVTMGEWWKWGFVVTLLNLLIFAGGCAV
HHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCEEECCHHHHHHHHHHHHHHHHHHCCHHH
WWKVLGYW
HHHHHCCC
>Mature Secondary Structure
MKLPHVKIVPAVIAFFVTCLFWFVISPPEGVDLNAWRLLGIFVGTITAIIGKALPIGGAA
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHH
MIGILLVGITQVTSPGNPGKAMGDALSGYSNTLIWLIGISFFISRAFIKTGLGSRVAYYF
HHHHHHHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
VRAIGKKTLGISYGLSFAELVLSPVMPSNTARGGGVLYPINRSISESMGSRPDEATRLKV
HHHHHHHHCCHHHCHHHHHHHHHCCCCCCCCCCCCEEEECCCHHHHHHCCCCCHHHHHHH
GAFLTLVAYQINVITSAMFITATAPNPLVTAGIRDIAKIDVSWAQWAMAAFVPGLLAILI
HHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IPWVLFKLYPPQIKETPDAAGYANKKLQELGPLRLDEKILIGVFFLLLFIWAGGPELLSS
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHCCC
DPLFKVDATAGAFVGLGVLLFSGVLTWDDLLKEKGAWDTVTWFSSLVMLATFLNKLGVVA
CCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
WFSKTVESSIAHWGLGWMEAAAILVLLYVFIHYFFASNTAHISALFASFFGVGVALGAPP
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHH
LMFGLFLGFASSLCASLTHYGTGSAPVLFGSGYVTMGEWWKWGFVVTLLNLLIFAGGCAV
HHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCEEECCHHHHHHHHHHHHHHHHHHCCHHH
WWKVLGYW
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9272861; 9384377; 12949159 [H]