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The map label for this gene is queD [H]

Identifier: 42523344

GI number: 42523344

Start: 1789262

End: 1789741

Strand: Direct

Name: queD [H]

Synonym: Bd1864

Alternate gene names: 42523344

Gene position: 1789262-1789741 (Clockwise)

Preceding gene: 42523341

Following gene: 42523346

Centisome position: 47.3

GC content: 47.71

Gene sequence:

>480_bases
TTGCATTTGGCAAAACAAAATTTCAAGTTCTCTGCCGCGCACTTTCTGATCTTTGATGAAACACACGCGGAGCGCCTGCA
CGGACATAACTATCAGGTGAAAGTCGACATCAAAACGCCTTCCGAAGAAGAACTGCATTCTGACGGTTACTTCCTTGATT
TCAATGTATTTAAAAAATACATCAAGGCCCGTTTGGATCAATGGGACGAGATGGTGCTGTTGCCAGAAAAGCAAAAAGAC
ATGAAATTCAAAAAAAACGGCCCGTCACTGGAAGTGACTTTCCGCGAGCGGTTTTATGCTTTCCCCGCCAATGAAGTCAC
CCTGCTGTCAGTGACCAACACCAGCGTGGAACAATTGTCCCGCCTGCTGGCAGAAGAATTCTTTGCTGAGTTCAAAAAGT
ATGGCGTGAAAAGTGTGCGCGTTTATGTTGCGGAAACCGCAGGGCAGGGCGCCTCCACGGTCGTGCCATCTAGGGCTTAA

Upstream 100 bases:

>100_bases
TGAGGCAGGAATCGCGCCGATTCAATTTGAAAATGCTGTTTCAGTTCGAATTTCATGCTAATACTATAGTCATTCCGAGG
TGAGTATGTCCACGACCACA

Downstream 100 bases:

>100_bases
GTTTGCCGCTGGAAACTTCAGAGGCTGACAGTTCGCGCACCACGCGATAGCGCCAGAAGCAGATACGTCCGCCTTCATTA
AGTTTTTGCTCCAGACGCTC

Product: 6-pyruvoyl-tetrahydropterin synthase, putative

Products: NA

Alternate protein names: CPH4 synthase; Archaeosine biosynthesis protein queD [H]

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MHLAKQNFKFSAAHFLIFDETHAERLHGHNYQVKVDIKTPSEEELHSDGYFLDFNVFKKYIKARLDQWDEMVLLPEKQKD
MKFKKNGPSLEVTFRERFYAFPANEVTLLSVTNTSVEQLSRLLAEEFFAEFKKYGVKSVRVYVAETAGQGASTVVPSRA

Sequences:

>Translated_159_residues
MHLAKQNFKFSAAHFLIFDETHAERLHGHNYQVKVDIKTPSEEELHSDGYFLDFNVFKKYIKARLDQWDEMVLLPEKQKD
MKFKKNGPSLEVTFRERFYAFPANEVTLLSVTNTSVEQLSRLLAEEFFAEFKKYGVKSVRVYVAETAGQGASTVVPSRA
>Mature_159_residues
MHLAKQNFKFSAAHFLIFDETHAERLHGHNYQVKVDIKTPSEEELHSDGYFLDFNVFKKYIKARLDQWDEMVLLPEKQKD
MKFKKNGPSLEVTFRERFYAFPANEVTLLSVTNTSVEQLSRLLAEEFFAEFKKYGVKSVRVYVAETAGQGASTVVPSRA

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde [H]

COG id: COG0720

COG function: function code H; 6-pyruvoyl-tetrahydropterin synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTPS family. QueD subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007116
- InterPro:   IPR007115 [H]

Pfam domain/function: PF01242 PTPS [H]

EC number: NA

Molecular weight: Translated: 18415; Mature: 18415

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHLAKQNFKFSAAHFLIFDETHAERLHGHNYQVKVDIKTPSEEELHSDGYFLDFNVFKKY
CCCCCCCCEEEEEEEEEEECCHHHHHCCCCEEEEEEECCCCHHHHCCCCEEEEHHHHHHH
IKARLDQWDEMVLLPEKQKDMKFKKNGPSLEVTFRERFYAFPANEVTLLSVTNTSVEQLS
HHHHHCCCCCEEECCCCCCCCEECCCCCCEEEEEHHEEEECCCCCEEEEEECCCCHHHHH
RLLAEEFFAEFKKYGVKSVRVYVAETAGQGASTVVPSRA
HHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MHLAKQNFKFSAAHFLIFDETHAERLHGHNYQVKVDIKTPSEEELHSDGYFLDFNVFKKY
CCCCCCCCEEEEEEEEEEECCHHHHHCCCCEEEEEEECCCCHHHHCCCCEEEEHHHHHHH
IKARLDQWDEMVLLPEKQKDMKFKKNGPSLEVTFRERFYAFPANEVTLLSVTNTSVEQLS
HHHHHCCCCCEEECCCCCCCCEECCCCCCEEEEEHHEEEECCCCCEEEEEECCCCHHHHH
RLLAEEFFAEFKKYGVKSVRVYVAETAGQGASTVVPSRA
HHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]