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The map label for this gene is pheT

Identifier: 42523140

GI number: 42523140

Start: 1573211

End: 1575652

Strand: Direct

Name: pheT

Synonym: Bd1638

Alternate gene names: 42523140

Gene position: 1573211-1575652 (Clockwise)

Preceding gene: 42523139

Following gene: 42523141

Centisome position: 41.59

GC content: 50.61

Gene sequence:

>2442_bases
ATGAAGATCAGTTTAAAATGGCTCCATGATTATGTTGATGTGACCGAATTCTTCCAAAAGCCGGAAGTGCTGGCGGAAGC
TTTGACCCGTGGCGGTTTGGAGGTTGAAGAAATCACCAATCGCGCGAAAGACTTCAATCACGTGGTGATTGGTCACATCC
TTGAAAAAGACAAGCATCCGAATGCGGATAAACTTTCCCTGTGTCGTGTTTCCACGGGCGAAGGTGTGGTTCACCAGATC
GTGTGTGGCGCACAAAACCACAAAGCGGGTGACCGTGTGATCGTGGCGTTGCCGGGGGCTGTATTGCCGGGCAATTTTGC
GATTAAAAAATCAGCGGTTCGTGGTGTGGATTCTGCCGGCATGCTGTGCTCTTTGAAAGAGCTGGGCTTGGCGACGGAAT
CGGAAGGCATTGCGATTTTGCCTGCGGATGCTCCGGTGGGTAAAGCTTATGCGGAATACGGCGGTTATGACGACGTGACT
TTCGAACTGAAAGTGACGGCGAATCGTGCAGACTGTCTGTCGCACTTCGGTTTGGCGCGTGAGGTTTCCACTTTGTTCGG
TAAAGAGCTGAAAGTGCCTTCCTCTGAGCTTAAAACCAATGGCAAATCCAGCAAGTCTGAAATTGCATTGGACGTCAAAG
CCTTCGATCTGTGCCCTCGTTACGCGGGTCGTTTCTTGAAGGGTGTGAAAGTGGGACCAAGTCCTGCCTGGTTGAAAGCG
CGCCTTGAAAGCGTGGGCATGAACTCCATCAACAACATCGTGGACGTGACAAACTACGTGATGTTGGAGCTGGGTCAGCC
ATTGCACGCCTTTGATGCGGCTTTCATCAACGGAAAAAAAATCATCGTGGACCGTGCCGTCGCTGGTGAAAAATTCATCA
CTCTGGACGGAACTGAAATCGCTCTGAACGGCGCTGAACTGACTATTCGTGATGTGAACCATCCGGTGTGTCTGGCGGGT
GTTGTGGGTGGCAAAAACTCGGGCGTTTCTGATTCCACGACCGAAGTCTTCCTGGAAGCGGCTTACTTCCTGCCGATGAG
TGCGCGTAAAACTTCACGTTCGCACGGTATCGACACGGATTCTTCTTACCGCTTTGCCCGTGGTGTGGATCCAGATGGAA
CTTTGCGCGGCTTGAACCGTGCCGCGGCTTTGATTTTGGAAGTGGCGGGTGGCGAAGCTTATGCTGATCATCATGACTTC
TATCCAAATCCGGTGAAAAAAGCGCCGGTGGATATCACCATCAAAACGGTTTCTGACCGTTTGGGTTATGAAGCTGAAGA
GCACAAATTCGTCGACTTCATGAAACGTCTGGGTTGTGAAATCAACAAAAAGGGCGAGACCTTCACGGTGCTTCCTCCGA
CCTTCCGTTTCGACATCGAACAGGACATGGACCTGGTTGAAGAGTACGCTCGCCTGAACGGGTATGAGCATATTCCAGAG
GCATTGCCGGCTTTGGCGGCAGCTCCAAGCTTCCAGGACAAGACTTTCATGTTGAACCGTACCACCAGCGAACTTTTGCG
TGGTGAGGGCTTCCAGCAAGCGGTGAACTTTGCCTTTGTTGGTTCCAAAGCTCAAAAAGCATTCTTGGGTTCTTTGGAGG
CCTTGAAAGCGACGGGTCTGGCAGCCACGGAAAAGGAAATCCGCATCTTGAATCCTCTGAATGAGGAAATGGATGTGATG
AGAAGCTCCTTGAGCTTTGGTCTGTTCAAAAACCTGAACCATAACTTCCACTCCGGCAACATGCAGGGTCGTCTGTTTGA
GATCGGCAGCACGTTCTTTGTTAAGGATGACGGAAGTTTTGCGGAAGGCAGCCGTGCCGGGATGGCTATCTGGGGTCGCG
CAAGCAACCTTTGGAACAAATCCCTGGATTATCCGGTTGTTTATGAACTTAAAGCGGCAGTTGAAGTTCTTTTGAAGTCT
TTGAATATCTCTTCTTACACCTGGGTGACTCCGGCGAATAAGTCCGAGGTTCCGGAGTTCCTGCATCAAGGGCAGTTTGC
ACAGCTTTTGGTGGAAGGTAAGAAAGTGGGCTTCATCGGCACACTTCATCCGCTTCTGCTTGAAGACAATAAGATCCGCG
TTCCTGCGGCTTTGGCCGAATTGGATCTGGATCAGCTTTATAAAGGTCAGCCTCGTCCATACCGCATCCAAAGCGTGTCC
AAGTTCCCGATCGTGGAGCGTGACTTCGCCTTTGTGATGCCAAAAGCCCTGAAAGTCGGCGATGTCCTGAAAGACATCCG
CAAGGCCGGAGCAGGTTTGCTTCTGAACGTGGACGTCTTTGACCTGTACGAAGGCGAGAAGATGGAAGCAGGCAAAAAAT
CCGTAGCGATTCGTATTTGGCTGCAGGATAAAAATGCCACACTGCAAGAAACCCAGATTAACGAGACAACAACCAAGATT
CTAGAGAGTCTGAAGAAGAATTTTGACCTTTCTGTGAGATAA

Upstream 100 bases:

>100_bases
TCGGATTTGGTGTTGAGCGTATGGCCATCATCAAGTACGGCATCGAAGACATCCGCTTGTTCCCTGAAAACGACGTAAGA
TTCTTAAGGCAGTTTGTAAA

Downstream 100 bases:

>100_bases
ATTCTTGATTGTTTTCAGTTAGTTGTTACGATTTTATGTAGCACTTGAAGAATTTTAATGGAGTGAATGACTATTATGGC
AGGCCAGAACTTAGGTAAAT

Product: phenylalanyl-tRNA synthetase beta chain

Products: NA

Alternate protein names: Phenylalanine--tRNA ligase beta chain; PheRS

Number of amino acids: Translated: 813; Mature: 813

Protein sequence:

>813_residues
MKISLKWLHDYVDVTEFFQKPEVLAEALTRGGLEVEEITNRAKDFNHVVIGHILEKDKHPNADKLSLCRVSTGEGVVHQI
VCGAQNHKAGDRVIVALPGAVLPGNFAIKKSAVRGVDSAGMLCSLKELGLATESEGIAILPADAPVGKAYAEYGGYDDVT
FELKVTANRADCLSHFGLAREVSTLFGKELKVPSSELKTNGKSSKSEIALDVKAFDLCPRYAGRFLKGVKVGPSPAWLKA
RLESVGMNSINNIVDVTNYVMLELGQPLHAFDAAFINGKKIIVDRAVAGEKFITLDGTEIALNGAELTIRDVNHPVCLAG
VVGGKNSGVSDSTTEVFLEAAYFLPMSARKTSRSHGIDTDSSYRFARGVDPDGTLRGLNRAAALILEVAGGEAYADHHDF
YPNPVKKAPVDITIKTVSDRLGYEAEEHKFVDFMKRLGCEINKKGETFTVLPPTFRFDIEQDMDLVEEYARLNGYEHIPE
ALPALAAAPSFQDKTFMLNRTTSELLRGEGFQQAVNFAFVGSKAQKAFLGSLEALKATGLAATEKEIRILNPLNEEMDVM
RSSLSFGLFKNLNHNFHSGNMQGRLFEIGSTFFVKDDGSFAEGSRAGMAIWGRASNLWNKSLDYPVVYELKAAVEVLLKS
LNISSYTWVTPANKSEVPEFLHQGQFAQLLVEGKKVGFIGTLHPLLLEDNKIRVPAALAELDLDQLYKGQPRPYRIQSVS
KFPIVERDFAFVMPKALKVGDVLKDIRKAGAGLLLNVDVFDLYEGEKMEAGKKSVAIRIWLQDKNATLQETQINETTTKI
LESLKKNFDLSVR

Sequences:

>Translated_813_residues
MKISLKWLHDYVDVTEFFQKPEVLAEALTRGGLEVEEITNRAKDFNHVVIGHILEKDKHPNADKLSLCRVSTGEGVVHQI
VCGAQNHKAGDRVIVALPGAVLPGNFAIKKSAVRGVDSAGMLCSLKELGLATESEGIAILPADAPVGKAYAEYGGYDDVT
FELKVTANRADCLSHFGLAREVSTLFGKELKVPSSELKTNGKSSKSEIALDVKAFDLCPRYAGRFLKGVKVGPSPAWLKA
RLESVGMNSINNIVDVTNYVMLELGQPLHAFDAAFINGKKIIVDRAVAGEKFITLDGTEIALNGAELTIRDVNHPVCLAG
VVGGKNSGVSDSTTEVFLEAAYFLPMSARKTSRSHGIDTDSSYRFARGVDPDGTLRGLNRAAALILEVAGGEAYADHHDF
YPNPVKKAPVDITIKTVSDRLGYEAEEHKFVDFMKRLGCEINKKGETFTVLPPTFRFDIEQDMDLVEEYARLNGYEHIPE
ALPALAAAPSFQDKTFMLNRTTSELLRGEGFQQAVNFAFVGSKAQKAFLGSLEALKATGLAATEKEIRILNPLNEEMDVM
RSSLSFGLFKNLNHNFHSGNMQGRLFEIGSTFFVKDDGSFAEGSRAGMAIWGRASNLWNKSLDYPVVYELKAAVEVLLKS
LNISSYTWVTPANKSEVPEFLHQGQFAQLLVEGKKVGFIGTLHPLLLEDNKIRVPAALAELDLDQLYKGQPRPYRIQSVS
KFPIVERDFAFVMPKALKVGDVLKDIRKAGAGLLLNVDVFDLYEGEKMEAGKKSVAIRIWLQDKNATLQETQINETTTKI
LESLKKNFDLSVR
>Mature_813_residues
MKISLKWLHDYVDVTEFFQKPEVLAEALTRGGLEVEEITNRAKDFNHVVIGHILEKDKHPNADKLSLCRVSTGEGVVHQI
VCGAQNHKAGDRVIVALPGAVLPGNFAIKKSAVRGVDSAGMLCSLKELGLATESEGIAILPADAPVGKAYAEYGGYDDVT
FELKVTANRADCLSHFGLAREVSTLFGKELKVPSSELKTNGKSSKSEIALDVKAFDLCPRYAGRFLKGVKVGPSPAWLKA
RLESVGMNSINNIVDVTNYVMLELGQPLHAFDAAFINGKKIIVDRAVAGEKFITLDGTEIALNGAELTIRDVNHPVCLAG
VVGGKNSGVSDSTTEVFLEAAYFLPMSARKTSRSHGIDTDSSYRFARGVDPDGTLRGLNRAAALILEVAGGEAYADHHDF
YPNPVKKAPVDITIKTVSDRLGYEAEEHKFVDFMKRLGCEINKKGETFTVLPPTFRFDIEQDMDLVEEYARLNGYEHIPE
ALPALAAAPSFQDKTFMLNRTTSELLRGEGFQQAVNFAFVGSKAQKAFLGSLEALKATGLAATEKEIRILNPLNEEMDVM
RSSLSFGLFKNLNHNFHSGNMQGRLFEIGSTFFVKDDGSFAEGSRAGMAIWGRASNLWNKSLDYPVVYELKAAVEVLLKS
LNISSYTWVTPANKSEVPEFLHQGQFAQLLVEGKKVGFIGTLHPLLLEDNKIRVPAALAELDLDQLYKGQPRPYRIQSVS
KFPIVERDFAFVMPKALKVGDVLKDIRKAGAGLLLNVDVFDLYEGEKMEAGKKSVAIRIWLQDKNATLQETQINETTTKI
LESLKKNFDLSVR

Specific function: Unknown

COG id: COG0072

COG function: function code J; Phenylalanyl-tRNA synthetase beta subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 tRNA-binding domain

Homologues:

Organism=Escherichia coli, GI1788006, Length=826, Percent_Identity=36.682808716707, Blast_Score=482, Evalue=1e-137,
Organism=Drosophila melanogaster, GI21355211, Length=308, Percent_Identity=26.6233766233766, Blast_Score=79, Evalue=9e-15,

Paralogues:

None

Copy number: 1,800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYFB_BDEBA (Q6MMJ1)

Other databases:

- EMBL:   BX842650
- RefSeq:   NP_968520.1
- ProteinModelPortal:   Q6MMJ1
- GeneID:   2735391
- GenomeReviews:   BX842601_GR
- KEGG:   bba:Bd1638
- NMPDR:   fig|264462.1.peg.1490
- HOGENOM:   HBG399638
- OMA:   ADKLRVC
- PhylomeDB:   Q6MMJ1
- BioCyc:   BBAC264462:BD1638-MONOMER
- BRENDA:   6.1.1.20
- GO:   GO:0005737
- HAMAP:   MF_00283
- InterPro:   IPR005146
- InterPro:   IPR005147
- InterPro:   IPR009061
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004532
- InterPro:   IPR020825
- InterPro:   IPR005121
- InterPro:   IPR002547
- Gene3D:   G3DSA:3.50.40.10
- Gene3D:   G3DSA:3.30.56.20
- Gene3D:   G3DSA:3.30.70.380
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00873
- SMART:   SM00874
- SMART:   SM00896
- TIGRFAMs:   TIGR00472

Pfam domain/function: PF03483 B3_4; PF03484 B5; PF03147 FDX-ACB; PF01588 tRNA_bind; SSF56037 B3_4; SSF54991 Fdx_AntiC_bd; SSF50249 Nucleic_acid_OB; SSF46955 Putativ_DNA_bind

EC number: =6.1.1.20

Molecular weight: Translated: 89252; Mature: 89252

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS51483 B5; PS51447 FDX_ACB; PS50886 TRBD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISLKWLHDYVDVTEFFQKPEVLAEALTRGGLEVEEITNRAKDFNHVVIGHILEKDKHP
CEEEHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHCCCCC
NADKLSLCRVSTGEGVVHQIVCGAQNHKAGDRVIVALPGAVLPGNFAIKKSAVRGVDSAG
CCCCEEEEEECCCCCHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCEEHHHHHCCCCCCC
MLCSLKELGLATESEGIAILPADAPVGKAYAEYGGYDDVTFELKVTANRADCLSHFGLAR
CEEEHHHHCCCCCCCCEEEEECCCCCCHHHHHCCCCCCEEEEEEEECCHHHHHHHHHHHH
EVSTLFGKELKVPSSELKTNGKSSKSEIALDVKAFDLCPRYAGRFLKGVKVGPSPAWLKA
HHHHHHCCCCCCCHHHHHCCCCCCCCEEEEEEHHHHHCHHHHHHHHHCCCCCCCHHHHHH
RLESVGMNSINNIVDVTNYVMLELGQPLHAFDAAFINGKKIIVDRAVAGEKFITLDGTEI
HHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEEECCCCEEEEECCCEE
ALNGAELTIRDVNHPVCLAGVVGGKNSGVSDSTTEVFLEAAYFLPMSARKTSRSHGIDTD
EEECCEEEEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCHHHCCHHCCCCCC
SSYRFARGVDPDGTLRGLNRAAALILEVAGGEAYADHHDFYPNPVKKAPVDITIKTVSDR
CCCCEECCCCCCHHHHHHHHHEEEEEEECCCCEECCCCCCCCCCCCCCCCEEEEEEEHHH
LGYEAEEHKFVDFMKRLGCEINKKGETFTVLPPTFRFDIEQDMDLVEEYARLNGYEHIPE
HCCCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCEEECCHHHHHHHHHHHHCCCCHHHHH
ALPALAAAPSFQDKTFMLNRTTSELLRGEGFQQAVNFAFVGSKAQKAFLGSLEALKATGL
HHHHHHCCCCCCCCEEEEECCHHHHHCCCCHHHHHCEEEECCHHHHHHHHHHHHHHHCCC
AATEKEIRILNPLNEEMDVMRSSLSFGLFKNLNHNFHSGNMQGRLFEIGSTFFVKDDGSF
CCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCEEEEECCCCC
AEGSRAGMAIWGRASNLWNKSLDYPVVYELKAAVEVLLKSLNISSYTWVTPANKSEVPEF
CCCCCCCEEEEECCHHHHCCCCCCCEEHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHH
LHQGQFAQLLVEGKKVGFIGTLHPLLLEDNKIRVPAALAELDLDQLYKGQPRPYRIQSVS
HHCCCHHHHHHCCCCEEEEECCCHHEECCCCEECCHHHHHCCHHHHHCCCCCCEEECCCC
KFPIVERDFAFVMPKALKVGDVLKDIRKAGAGLLLNVDVFDLYEGEKMEAGKKSVAIRIW
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCEEEEEEE
LQDKNATLQETQINETTTKILESLKKNFDLSVR
EECCCCEEECCCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKISLKWLHDYVDVTEFFQKPEVLAEALTRGGLEVEEITNRAKDFNHVVIGHILEKDKHP
CEEEHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHCCCCC
NADKLSLCRVSTGEGVVHQIVCGAQNHKAGDRVIVALPGAVLPGNFAIKKSAVRGVDSAG
CCCCEEEEEECCCCCHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCEEHHHHHCCCCCCC
MLCSLKELGLATESEGIAILPADAPVGKAYAEYGGYDDVTFELKVTANRADCLSHFGLAR
CEEEHHHHCCCCCCCCEEEEECCCCCCHHHHHCCCCCCEEEEEEEECCHHHHHHHHHHHH
EVSTLFGKELKVPSSELKTNGKSSKSEIALDVKAFDLCPRYAGRFLKGVKVGPSPAWLKA
HHHHHHCCCCCCCHHHHHCCCCCCCCEEEEEEHHHHHCHHHHHHHHHCCCCCCCHHHHHH
RLESVGMNSINNIVDVTNYVMLELGQPLHAFDAAFINGKKIIVDRAVAGEKFITLDGTEI
HHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEEECCCCEEEEECCCEE
ALNGAELTIRDVNHPVCLAGVVGGKNSGVSDSTTEVFLEAAYFLPMSARKTSRSHGIDTD
EEECCEEEEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCHHHCCHHCCCCCC
SSYRFARGVDPDGTLRGLNRAAALILEVAGGEAYADHHDFYPNPVKKAPVDITIKTVSDR
CCCCEECCCCCCHHHHHHHHHEEEEEEECCCCEECCCCCCCCCCCCCCCCEEEEEEEHHH
LGYEAEEHKFVDFMKRLGCEINKKGETFTVLPPTFRFDIEQDMDLVEEYARLNGYEHIPE
HCCCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCEEECCHHHHHHHHHHHHCCCCHHHHH
ALPALAAAPSFQDKTFMLNRTTSELLRGEGFQQAVNFAFVGSKAQKAFLGSLEALKATGL
HHHHHHCCCCCCCCEEEEECCHHHHHCCCCHHHHHCEEEECCHHHHHHHHHHHHHHHCCC
AATEKEIRILNPLNEEMDVMRSSLSFGLFKNLNHNFHSGNMQGRLFEIGSTFFVKDDGSF
CCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCEEEEECCCCC
AEGSRAGMAIWGRASNLWNKSLDYPVVYELKAAVEVLLKSLNISSYTWVTPANKSEVPEF
CCCCCCCEEEEECCHHHHCCCCCCCEEHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHH
LHQGQFAQLLVEGKKVGFIGTLHPLLLEDNKIRVPAALAELDLDQLYKGQPRPYRIQSVS
HHCCCHHHHHHCCCCEEEEECCCHHEECCCCEECCHHHHHCCHHHHHCCCCCCEEECCCC
KFPIVERDFAFVMPKALKVGDVLKDIRKAGAGLLLNVDVFDLYEGEKMEAGKKSVAIRIW
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCEEEEEEE
LQDKNATLQETQINETTTKILESLKKNFDLSVR
EECCCCEEECCCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA