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The map label for this gene is potC [H]

Identifier: 42522937

GI number: 42522937

Start: 1342310

End: 1343143

Strand: Direct

Name: potC [H]

Synonym: Bd1421

Alternate gene names: 42522937

Gene position: 1342310-1343143 (Clockwise)

Preceding gene: 42522936

Following gene: 42522938

Centisome position: 35.48

GC content: 53.6

Gene sequence:

>834_bases
GTGGTTGAACGAAGCCGTCCTCAGGCGCCCATGTTTGCGAAAGTCGTTCTGTGGATAACACTGCTTTTGCTGCACACTCC
GATTCTGGTGATGATTCTGGGCGCTTTGATTGAAAAGAAACCGGATTCCTGGAGCTGGACACTGCGCTGGTTCTCCGAAG
TCGTGAATGATCAGGCCCTGATGGACGCCTTGAAAAACAGTCTGCTGGTGGGTGTAGCGGCAAGTCTGCTTTCAACCGTG
ATTGGCACCAGTGCAGCTGTGGGGTTGCACCGTTCGGCCGGCGGCTGGCGTTGGGCGGTCGAGGGGTTGTCCGTGGTTTC
GCTGGTTTTCCCTGAGATTGTTTTTGCCTTGTCGCTGTTGTCGTTGTTTTTCATTTTACAGTTTGAGCTGGGTCTGATGA
CTGTGGTGATTTCCCACGTCAGCTTCAGCATCTCCTATGTGATGATCACGGTCGGGGCCCGGCTGGCGACGCTGGATCGC
AGTTTTGAGGATGCCGCCCGGGATCTGGGGGCTTCAGAGTGGCAGACCTATCGTTCGGTGGTGCTGCCATTGCTGGGGCC
TTCGATCGTCGGTGGTGGGGCGTTAAGTTTTCTGCTTTCCTTTGATGATTTCCTGATCACGTACTTTGTGAATGGCGTGG
GGCAGGACACGCTGCCAGTCAAACTTTACACGGCGATGAAGCTGGGGGTCAGCCCCAAACTCAATGCGCTTTCCAGTCTG
ATGTTTGTTATGACTTTGCTGGCGCTGATTTTCTTCTTCCGTTCTTCCGCGTTCCGTGTTTTCTTTGAAGCGCGGGGGAA
GCATGAATCCAAATCAGAAAAAGAAAATCCTTAG

Upstream 100 bases:

>100_bases
GCCCGCGACTGGCCCTTTGGGGCGGCATTGTCGGTGCTGATGATGCTGCTTTTGCTGGTGATGGCGCTGGTGTTCAGAAT
GTGGGAGGCGCGCCGTGCCC

Downstream 100 bases:

>100_bases
CTGGGCTTTTTATGACTGGGCCAACAGTGGTTATGCCACGACGGTCATGGCTGCATTTTTCCCGGTCTTTCTGAAGCAAT
ATTGGAGCGTCGGCACTGAC

Product: spermidine/putrescine transport system permease protein

Products: Phosphate; putrescine [Cytoplasm]; ADP; spermidine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MVERSRPQAPMFAKVVLWITLLLLHTPILVMILGALIEKKPDSWSWTLRWFSEVVNDQALMDALKNSLLVGVAASLLSTV
IGTSAAVGLHRSAGGWRWAVEGLSVVSLVFPEIVFALSLLSLFFILQFELGLMTVVISHVSFSISYVMITVGARLATLDR
SFEDAARDLGASEWQTYRSVVLPLLGPSIVGGGALSFLLSFDDFLITYFVNGVGQDTLPVKLYTAMKLGVSPKLNALSSL
MFVMTLLALIFFFRSSAFRVFFEARGKHESKSEKENP

Sequences:

>Translated_277_residues
MVERSRPQAPMFAKVVLWITLLLLHTPILVMILGALIEKKPDSWSWTLRWFSEVVNDQALMDALKNSLLVGVAASLLSTV
IGTSAAVGLHRSAGGWRWAVEGLSVVSLVFPEIVFALSLLSLFFILQFELGLMTVVISHVSFSISYVMITVGARLATLDR
SFEDAARDLGASEWQTYRSVVLPLLGPSIVGGGALSFLLSFDDFLITYFVNGVGQDTLPVKLYTAMKLGVSPKLNALSSL
MFVMTLLALIFFFRSSAFRVFFEARGKHESKSEKENP
>Mature_277_residues
MVERSRPQAPMFAKVVLWITLLLLHTPILVMILGALIEKKPDSWSWTLRWFSEVVNDQALMDALKNSLLVGVAASLLSTV
IGTSAAVGLHRSAGGWRWAVEGLSVVSLVFPEIVFALSLLSLFFILQFELGLMTVVISHVSFSISYVMITVGARLATLDR
SFEDAARDLGASEWQTYRSVVLPLLGPSIVGGGALSFLLSFDDFLITYFVNGVGQDTLPVKLYTAMKLGVSPKLNALSSL
MFVMTLLALIFFFRSSAFRVFFEARGKHESKSEKENP

Specific function: Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine [H]

COG id: COG1177

COG function: function code E; ABC-type spermidine/putrescine transport system, permease component II

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787368, Length=205, Percent_Identity=38.5365853658537, Blast_Score=154, Evalue=6e-39,
Organism=Escherichia coli, GI1787081, Length=241, Percent_Identity=34.0248962655602, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1787714, Length=251, Percent_Identity=35.0597609561753, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1788764, Length=180, Percent_Identity=31.6666666666667, Blast_Score=71, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30484; Mature: 30484

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Putrescine [Periplasm]; H2O; ATP; spermidine [Periplasm] [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] ATP + spermidine [Periplasm] + H2O = ADP + phosphate + spermidine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]