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The map label for this gene is map [H]

Identifier: 42522858

GI number: 42522858

Start: 1264924

End: 1265688

Strand: Direct

Name: map [H]

Synonym: Bd1338

Alternate gene names: 42522858

Gene position: 1264924-1265688 (Clockwise)

Preceding gene: 42522857

Following gene: 42522859

Centisome position: 33.44

GC content: 47.97

Gene sequence:

>765_bases
ATGGGAATTAAGCCGCTTTCTTTGGAAGAAATCAAAAAGATGACTGTTGCCTGCCGTATTGCAGCCGACACGCTCACTTA
CCTGGATAAATATATCAAAATTGGTATGACCACGAACGAGATCGATCAGCTTTGCTTCGATTTTATGGCGACCAAAGGTG
CCAAGTCCGCATGTCTGGGGTATCACGGCTATCCTAAGTACACTTGTACTTCTATCAATGAAGTTGTCTGCCATGGCGTT
CCTGATGACAAGACCATCTTGAAAGACGGGGACATTATCAATGTCGACGTGACTGCTTGGATTGATGGTTTCTTTGGGGA
CACGTCCAAGATGTACATGATCGGTAACGTTTCTGAAGAAGCCAAGGACCTGGTGGAAACCGCCCGTATGGCTCGTGATA
TCGGTATCGAAGCGATTCGACCGAACGGTTATACCGGGGACATCGGTTTCGAAACGAACAAGCTTGTGACCCGCAAGGGG
TATGTGGCCGTGAAAGAGATCGGTGGGCACGGTGTGGGCCGCAAGTTCCACGAAGAGCCGTTTGTTCCGTCCTATGGCAA
AAAGGGCAAGGGCGAGCGCCTGGTGCCGTTCCACTGTATCACCGTCGAACCGATGGTGAATCAAGGGACTGACGAAATCA
TCGAATTCGACATTCCAGGAAGCAGCATTAAGTACTATCATACTGCAGATAGTCTACTGTCCGCACAATTTGAACATACA
GTTCTTGTGACGGATACTGGATATGAAATCTTAACTTTACCATAA

Upstream 100 bases:

>100_bases
GGAAACGGCGGCTTTTATCTAAGGTGGACTTGGATTTTCCCTGTTGGGAGTTGGGGTTTTGGTCTGTTCAAGGGTGGGGG
GCTGTGCTATACCATCCTCT

Downstream 100 bases:

>100_bases
TTTTTAAAAACCTAAGACAAGGACTTCAATCAAATGTCATTGACTACGACGAACGGAAAAACCGCTATGAAGAAAAATGC
TAAAATGAAAGCTCCTACAG

Product: hypothetical protein

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MGIKPLSLEEIKKMTVACRIAADTLTYLDKYIKIGMTTNEIDQLCFDFMATKGAKSACLGYHGYPKYTCTSINEVVCHGV
PDDKTILKDGDIINVDVTAWIDGFFGDTSKMYMIGNVSEEAKDLVETARMARDIGIEAIRPNGYTGDIGFETNKLVTRKG
YVAVKEIGGHGVGRKFHEEPFVPSYGKKGKGERLVPFHCITVEPMVNQGTDEIIEFDIPGSSIKYYHTADSLLSAQFEHT
VLVTDTGYEILTLP

Sequences:

>Translated_254_residues
MGIKPLSLEEIKKMTVACRIAADTLTYLDKYIKIGMTTNEIDQLCFDFMATKGAKSACLGYHGYPKYTCTSINEVVCHGV
PDDKTILKDGDIINVDVTAWIDGFFGDTSKMYMIGNVSEEAKDLVETARMARDIGIEAIRPNGYTGDIGFETNKLVTRKG
YVAVKEIGGHGVGRKFHEEPFVPSYGKKGKGERLVPFHCITVEPMVNQGTDEIIEFDIPGSSIKYYHTADSLLSAQFEHT
VLVTDTGYEILTLP
>Mature_253_residues
GIKPLSLEEIKKMTVACRIAADTLTYLDKYIKIGMTTNEIDQLCFDFMATKGAKSACLGYHGYPKYTCTSINEVVCHGVP
DDKTILKDGDIINVDVTAWIDGFFGDTSKMYMIGNVSEEAKDLVETARMARDIGIEAIRPNGYTGDIGFETNKLVTRKGY
VAVKEIGGHGVGRKFHEEPFVPSYGKKGKGERLVPFHCITVEPMVNQGTDEIIEFDIPGSSIKYYHTADSLLSAQFEHTV
LVTDTGYEILTLP

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI40385867, Length=247, Percent_Identity=37.246963562753, Blast_Score=167, Evalue=6e-42,
Organism=Homo sapiens, GI164420681, Length=250, Percent_Identity=37.2, Blast_Score=166, Evalue=2e-41,
Organism=Escherichia coli, GI1786364, Length=254, Percent_Identity=46.0629921259843, Blast_Score=221, Evalue=5e-59,
Organism=Caenorhabditis elegans, GI71996291, Length=251, Percent_Identity=37.4501992031873, Blast_Score=159, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6323273, Length=245, Percent_Identity=38.3673469387755, Blast_Score=174, Evalue=1e-44,
Organism=Drosophila melanogaster, GI21355531, Length=250, Percent_Identity=40.8, Blast_Score=189, Evalue=1e-48,
Organism=Drosophila melanogaster, GI24583427, Length=243, Percent_Identity=36.2139917695473, Blast_Score=151, Evalue=5e-37,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 28070; Mature: 27939

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIKPLSLEEIKKMTVACRIAADTLTYLDKYIKIGMTTNEIDQLCFDFMATKGAKSACLG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHCCCCCHHEEC
YHGYPKYTCTSINEVVCHGVPDDKTILKDGDIINVDVTAWIDGFFGDTSKMYMIGNVSEE
CCCCCCEEECCHHHHEECCCCCCCEEEECCCEEEEEHHEEEECCCCCCCCEEEEECCCHH
AKDLVETARMARDIGIEAIRPNGYTGDIGFETNKLVTRKGYVAVKEIGGHGVGRKFHEEP
HHHHHHHHHHHHHCCCEEECCCCEECCCCCCCCEEEEECCCEEEEECCCCCCCCCCCCCC
FVPSYGKKGKGERLVPFHCITVEPMVNQGTDEIIEFDIPGSSIKYYHTADSLLSAQFEHT
CCCCCCCCCCCCEECEEEEEEECCCCCCCCCCEEEEECCCCCEEEEECHHHHHHHCCCEE
VLVTDTGYEILTLP
EEEEECCEEEEECC
>Mature Secondary Structure 
GIKPLSLEEIKKMTVACRIAADTLTYLDKYIKIGMTTNEIDQLCFDFMATKGAKSACLG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHCCCCCHHEEC
YHGYPKYTCTSINEVVCHGVPDDKTILKDGDIINVDVTAWIDGFFGDTSKMYMIGNVSEE
CCCCCCEEECCHHHHEECCCCCCCEEEECCCEEEEEHHEEEECCCCCCCCEEEEECCCHH
AKDLVETARMARDIGIEAIRPNGYTGDIGFETNKLVTRKGYVAVKEIGGHGVGRKFHEEP
HHHHHHHHHHHHHCCCEEECCCCEECCCCCCCCEEEEECCCEEEEECCCCCCCCCCCCCC
FVPSYGKKGKGERLVPFHCITVEPMVNQGTDEIIEFDIPGSSIKYYHTADSLLSAQFEHT
CCCCCCCCCCCCEECEEEEEEECCCCCCCCCCEEEEECCCCCEEEEECHHHHHHHCCCEE
VLVTDTGYEILTLP
EEEEECCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]