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The map label for this gene is aer [H]

Identifier: 42522843

GI number: 42522843

Start: 1250101

End: 1251462

Strand: Direct

Name: aer [H]

Synonym: Bd1322

Alternate gene names: 42522843

Gene position: 1250101-1251462 (Clockwise)

Preceding gene: 42522842

Following gene: 42522846

Centisome position: 33.05

GC content: 49.49

Gene sequence:

>1362_bases
ATGAAACGTCCCGTGCCCACCCAAGCTGAAAGCCCTTTCGGGTTTGATGAGTTCTTTTTTTCAACAACCGACAAACGTGG
CGTTATCCGTTATGGAAATGATGTCTTTGTTCGTGTCAGCGTTTATCCCAAAGAATCCATGTTGGGTGCTCCGCACAGTC
TGATCCGCCATCCTGACATGCCTCGTGCCGTGTTTAAGGAATTCTGGAGCTTTCTGAATCAGGGGAAAGCCGTCGGAGCA
TACGTTAAGAATCTGGCCGGGAACGGCAGTTATTATTGGGTGTATGCGTTCGCCTTTCCGATTGGCGATGGGTATTTGTC
TGTTCGATTCAAGCCCTCTTCAGAGTTGTTTTCAGTTGTGCAGGGTCTTTATAAAGAGGTCCTGGCTTACGAGCAGCAGG
AACACAGTCTGGAAGAGTCCCATCAGCACTTGCTGCTGAAGATCCAAGAGGCCGGGTTCCCTGACTATGAAAGCTTTATG
ATGAAGGCTGTCATGGAGGAGCTGAAGGCCCGGGCTGCCCAGGTGCTGGCCTCTGAATCCAGATCGTCCGGAGCCACCGG
TGCCAGTCAGATCACTGCGGTCACAAATTCCACCACACGCAAGCTGAATGATGTTTTTGATAAGCTGCGGGACTTTCAAG
GGGCCAATCAAAGTCTTGAAAGTGCTATGGGTCGTCTGGATCAGGGCTTTCAGCAGCTGAAGTTTATTTCCATCAATATG
AAAATCGCGGCTGCCAAATTTGGCGAGATGGCGGCAAGTCTGGGTGTGGTTTCCCACGAATTTTCAGTGTTGTCGGGCAC
TATTGAAAAGCACCTGGGCGGTCTTTCCGGGTTTGTTGAGGAATTGTCTAGTGTGATTCAAAAGTGTGTCTTGCGTGCAG
CGGCCCTGAATGTGCAGATGCTGATGGTGGACTTTTTTGTTCGCGAATCCATCGCCAAGCTGGCAACTTCAGAAAACGCT
TTCGACGAGATGCTGCAGAATCAGAAGGCCTTTTCCGATCTTTTTGCCCAGTATTGCCAAAATCTCGATAAAGAGTTTTC
CGAGCTGAAAAAAAGCCTGTCCGCGATTTCCTATGAGATGCTGGAAGTGGCCAAGTTTGTGACCGGACTTGAAGTGGTTC
GTCAGATGGGGGCGATTGAGTCGGCGCGAACAACTGAGATTAGAAACAGTTTCACGCACTATCTGGAAGCAATGGATGAT
TTTATTCAGTTGCTGCGCGAAAGTACCGGTGAAATCGGCCGGGGTGTGACTTCCCTGGCCTCAAATTCCGAATTCATTGT
GTCTTCCATTCGCAATATTTCAGGAAATGTGGATCAGATCTTTGCTCTTGCTTCCTCGCAAGAGCAGCAGAAAGCCGGCT
AA

Upstream 100 bases:

>100_bases
TGAAGCCTGAGCAACCATCACTTTCGTGAATGAGTGCTAAGGCTATGTCCGGGAAGTGCCGATCAAAAAACTGTTAAAAA
GTTTTTTTCGAGAGGATTCC

Downstream 100 bases:

>100_bases
TCAGCCTTTCATGGCTTCCTTGAATTCTGGCGGCAGCGGGGCTTCAAAAGAGTGTTTATAGCCATTGATCATCACGGTCA
TGCGCGCTGCGTGCAGGAAC

Product: putative sensory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MKRPVPTQAESPFGFDEFFFSTTDKRGVIRYGNDVFVRVSVYPKESMLGAPHSLIRHPDMPRAVFKEFWSFLNQGKAVGA
YVKNLAGNGSYYWVYAFAFPIGDGYLSVRFKPSSELFSVVQGLYKEVLAYEQQEHSLEESHQHLLLKIQEAGFPDYESFM
MKAVMEELKARAAQVLASESRSSGATGASQITAVTNSTTRKLNDVFDKLRDFQGANQSLESAMGRLDQGFQQLKFISINM
KIAAAKFGEMAASLGVVSHEFSVLSGTIEKHLGGLSGFVEELSSVIQKCVLRAAALNVQMLMVDFFVRESIAKLATSENA
FDEMLQNQKAFSDLFAQYCQNLDKEFSELKKSLSAISYEMLEVAKFVTGLEVVRQMGAIESARTTEIRNSFTHYLEAMDD
FIQLLRESTGEIGRGVTSLASNSEFIVSSIRNISGNVDQIFALASSQEQQKAG

Sequences:

>Translated_453_residues
MKRPVPTQAESPFGFDEFFFSTTDKRGVIRYGNDVFVRVSVYPKESMLGAPHSLIRHPDMPRAVFKEFWSFLNQGKAVGA
YVKNLAGNGSYYWVYAFAFPIGDGYLSVRFKPSSELFSVVQGLYKEVLAYEQQEHSLEESHQHLLLKIQEAGFPDYESFM
MKAVMEELKARAAQVLASESRSSGATGASQITAVTNSTTRKLNDVFDKLRDFQGANQSLESAMGRLDQGFQQLKFISINM
KIAAAKFGEMAASLGVVSHEFSVLSGTIEKHLGGLSGFVEELSSVIQKCVLRAAALNVQMLMVDFFVRESIAKLATSENA
FDEMLQNQKAFSDLFAQYCQNLDKEFSELKKSLSAISYEMLEVAKFVTGLEVVRQMGAIESARTTEIRNSFTHYLEAMDD
FIQLLRESTGEIGRGVTSLASNSEFIVSSIRNISGNVDQIFALASSQEQQKAG
>Mature_453_residues
MKRPVPTQAESPFGFDEFFFSTTDKRGVIRYGNDVFVRVSVYPKESMLGAPHSLIRHPDMPRAVFKEFWSFLNQGKAVGA
YVKNLAGNGSYYWVYAFAFPIGDGYLSVRFKPSSELFSVVQGLYKEVLAYEQQEHSLEESHQHLLLKIQEAGFPDYESFM
MKAVMEELKARAAQVLASESRSSGATGASQITAVTNSTTRKLNDVFDKLRDFQGANQSLESAMGRLDQGFQQLKFISINM
KIAAAKFGEMAASLGVVSHEFSVLSGTIEKHLGGLSGFVEELSSVIQKCVLRAAALNVQMLMVDFFVRESIAKLATSENA
FDEMLQNQKAFSDLFAQYCQNLDKEFSELKKSLSAISYEMLEVAKFVTGLEVVRQMGAIESARTTEIRNSFTHYLEAMDD
FIQLLRESTGEIGRGVTSLASNSEFIVSSIRNISGNVDQIFALASSQEQQKAG

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=127, Percent_Identity=40.1574803149606, Blast_Score=115, Evalue=8e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 50356; Mature: 50356

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRPVPTQAESPFGFDEFFFSTTDKRGVIRYGNDVFVRVSVYPKESMLGAPHSLIRHPDM
CCCCCCCCCCCCCCHHHHHHCCCCCCCCEEECCEEEEEEEECCCHHHCCCCHHHHCCCCC
PRAVFKEFWSFLNQGKAVGAYVKNLAGNGSYYWVYAFAFPIGDGYLSVRFKPSSELFSVV
CHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEEEEEEECCCEEEEEECCHHHHHHHH
QGLYKEVLAYEQQEHSLEESHQHLLLKIQEAGFPDYESFMMKAVMEELKARAAQVLASES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
RSSGATGASQITAVTNSTTRKLNDVFDKLRDFQGANQSLESAMGRLDQGFQQLKFISINM
CCCCCCCHHHEEEHHCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEEEEE
KIAAAKFGEMAASLGVVSHEFSVLSGTIEKHLGGLSGFVEELSSVIQKCVLRAAALNVQM
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMVDFFVRESIAKLATSENAFDEMLQNQKAFSDLFAQYCQNLDKEFSELKKSLSAISYEM
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEVAKFVTGLEVVRQMGAIESARTTEIRNSFTHYLEAMDDFIQLLRESTGEIGRGVTSLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
SNSEFIVSSIRNISGNVDQIFALASSQEQQKAG
CCCHHHHHHHHHCCCCHHHHHHHHCCCHHHCCC
>Mature Secondary Structure
MKRPVPTQAESPFGFDEFFFSTTDKRGVIRYGNDVFVRVSVYPKESMLGAPHSLIRHPDM
CCCCCCCCCCCCCCHHHHHHCCCCCCCCEEECCEEEEEEEECCCHHHCCCCHHHHCCCCC
PRAVFKEFWSFLNQGKAVGAYVKNLAGNGSYYWVYAFAFPIGDGYLSVRFKPSSELFSVV
CHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEEEEEEECCCEEEEEECCHHHHHHHH
QGLYKEVLAYEQQEHSLEESHQHLLLKIQEAGFPDYESFMMKAVMEELKARAAQVLASES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
RSSGATGASQITAVTNSTTRKLNDVFDKLRDFQGANQSLESAMGRLDQGFQQLKFISINM
CCCCCCCHHHEEEHHCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEEEEE
KIAAAKFGEMAASLGVVSHEFSVLSGTIEKHLGGLSGFVEELSSVIQKCVLRAAALNVQM
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMVDFFVRESIAKLATSENAFDEMLQNQKAFSDLFAQYCQNLDKEFSELKKSLSAISYEM
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEVAKFVTGLEVVRQMGAIESARTTEIRNSFTHYLEAMDDFIQLLRESTGEIGRGVTSLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
SNSEFIVSSIRNISGNVDQIFALASSQEQQKAG
CCCHHHHHHHHHCCCCHHHHHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]