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The map label for this gene is mcp [H]

Identifier: 42522674

GI number: 42522674

Start: 1063257

End: 1064696

Strand: Direct

Name: mcp [H]

Synonym: Bd1126

Alternate gene names: 42522674

Gene position: 1063257-1064696 (Clockwise)

Preceding gene: 42522673

Following gene: 42522676

Centisome position: 28.11

GC content: 52.64

Gene sequence:

>1440_bases
ATGAAACAACTGAGTCTAAGTCAGAAAATGAGTCTTATCGTTGCCATCCTCTGTGCGGGTATCGTGGGTGTGGCCGGCGT
CGGACTGTACAATTTAAAGCGTGTCGGAGACGTGGTTTCCAATGTCACCGATGTCCAGTTTAAGAGCGTTGTTGAAGCCC
TGAACCTGAAGGATGCCTTTCACGGGCAGATGATCTATGAAAGAAACTATGTGCTTTTCTATGATAATCTGGAAAAACGT
GCCAACAACTCGGCCCAGATTAAAAAACTCGACAGCGGGATTCGCACCATTGTTGCCGATCGTATGCAGGTCGCCGATGC
GACGGAAAAAAGCAGTCTGGAAAAGTTTCTGACCACGTACAATCGTTGGTCGGACAACGATCTGGAAATTCAAAAAATCA
TGGCCGATGCTGATGGCCACCAAAAAGCATTGGGTCTGATTTCTTCCGTGGGCCGTGATACACGTCTGGAAGGCGACAAG
GCCCTGGATGAAATCCTGACTCATCATCAGGCCCAGTTGGAAGAGCAAAAGAAAAAATCGGCAGATGCCATCTCCAGTAC
CTTCCAGATTCTGATCTGGACCGGCAGTGCGGTGATTTTACTGGGCGTGCTGTTGGCGGCAATGACCCTGCGAAAGATGT
CAGCGGCGATCAGCAGCGTTCTTAGAAACCTGGGTGAAAATGCCTTTCAGGTGAATCACACGGCAACACAGATTGCGACC
GCATCCCAGGGGCTTTCACAAAGTGCCACCGAGCAGGCTTCTTCTCTGGAGGAGACGGTGGCAACCATCGAAGAGCTGAC
CGCCATGGTGCGTATCAATGCTGAAAATGCGGCCTCGGCCACGGATCTGGCAGAAGGCACCCGACGAAGTGCTGAAGACG
GTGAACGGAAAATTCAAGGCCTGCTTGAGGCGATGAAAGTCATTGATCAGGATTCCAAAAAAATCCAGGAAATCACCAGC
GTCGTTGATGATCTGGCCTTCCAGACAAATTTGCTGGCGCTCAATGCCGCCGTGGAAGCCGCCCGTGCCGGCGAGCAGGG
AAAAGGATTTGCAGTGGTCGCCGAAGCCGTGCGCACGCTGGCGCTGAAAAGCAGTGACGCAGCCAAGGACATCTCCAATC
TGATCAACTCCAGTGTGGAGCGCATTCAGGCCGGATTTGAGCGGGCCAATGAAAGTGTCGATTCTTTGACTGAAATTGTG
GGCTCGGTGAAAAAGGTTTCTAGCTTAAACTCTGAAATCGCCAGCGCCACCAGCGAGCAGTCCAATGGCATCACGCAAAT
CGGCAAGGCGATGAATCAGCTCGACACGGTCACTCAGGAAAATGCGGCGGCTTCCGAACAAGCGGCGGCGTCTTCGCAGG
AGCTGGCGGGGCAGGCGACAGTTCTGAACAAAGTCGTGGAAGAACTTCGTGTGGCTATCAAGGGCAGTGCTTCGGCTTAG

Upstream 100 bases:

>100_bases
ATTGTGACATCCTGTCGCCTTCCTTGAACCTTGTCTTAGTGTAATGAAGTTTCCTGGTTTGTGGGCCGAAGAACGCTGCA
CTTATATTAAGGGAGCGTTC

Downstream 100 bases:

>100_bases
AAACCCTGCTGTACCAGAGATTTAACAAAGACCCGGGCGGGTTTGGCCAATTGGTGCTCGCCCAGGTGAATCAGATATAT
CTTATAGCGGATCTTGCCAG

Product: putative methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 479; Mature: 479

Protein sequence:

>479_residues
MKQLSLSQKMSLIVAILCAGIVGVAGVGLYNLKRVGDVVSNVTDVQFKSVVEALNLKDAFHGQMIYERNYVLFYDNLEKR
ANNSAQIKKLDSGIRTIVADRMQVADATEKSSLEKFLTTYNRWSDNDLEIQKIMADADGHQKALGLISSVGRDTRLEGDK
ALDEILTHHQAQLEEQKKKSADAISSTFQILIWTGSAVILLGVLLAAMTLRKMSAAISSVLRNLGENAFQVNHTATQIAT
ASQGLSQSATEQASSLEETVATIEELTAMVRINAENAASATDLAEGTRRSAEDGERKIQGLLEAMKVIDQDSKKIQEITS
VVDDLAFQTNLLALNAAVEAARAGEQGKGFAVVAEAVRTLALKSSDAAKDISNLINSSVERIQAGFERANESVDSLTEIV
GSVKKVSSLNSEIASATSEQSNGITQIGKAMNQLDTVTQENAAASEQAAASSQELAGQATVLNKVVEELRVAIKGSASA

Sequences:

>Translated_479_residues
MKQLSLSQKMSLIVAILCAGIVGVAGVGLYNLKRVGDVVSNVTDVQFKSVVEALNLKDAFHGQMIYERNYVLFYDNLEKR
ANNSAQIKKLDSGIRTIVADRMQVADATEKSSLEKFLTTYNRWSDNDLEIQKIMADADGHQKALGLISSVGRDTRLEGDK
ALDEILTHHQAQLEEQKKKSADAISSTFQILIWTGSAVILLGVLLAAMTLRKMSAAISSVLRNLGENAFQVNHTATQIAT
ASQGLSQSATEQASSLEETVATIEELTAMVRINAENAASATDLAEGTRRSAEDGERKIQGLLEAMKVIDQDSKKIQEITS
VVDDLAFQTNLLALNAAVEAARAGEQGKGFAVVAEAVRTLALKSSDAAKDISNLINSSVERIQAGFERANESVDSLTEIV
GSVKKVSSLNSEIASATSEQSNGITQIGKAMNQLDTVTQENAAASEQAAASSQELAGQATVLNKVVEELRVAIKGSASA
>Mature_479_residues
MKQLSLSQKMSLIVAILCAGIVGVAGVGLYNLKRVGDVVSNVTDVQFKSVVEALNLKDAFHGQMIYERNYVLFYDNLEKR
ANNSAQIKKLDSGIRTIVADRMQVADATEKSSLEKFLTTYNRWSDNDLEIQKIMADADGHQKALGLISSVGRDTRLEGDK
ALDEILTHHQAQLEEQKKKSADAISSTFQILIWTGSAVILLGVLLAAMTLRKMSAAISSVLRNLGENAFQVNHTATQIAT
ASQGLSQSATEQASSLEETVATIEELTAMVRINAENAASATDLAEGTRRSAEDGERKIQGLLEAMKVIDQDSKKIQEITS
VVDDLAFQTNLLALNAAVEAARAGEQGKGFAVVAEAVRTLALKSSDAAKDISNLINSSVERIQAGFERANESVDSLTEIV
GSVKKVSSLNSEIASATSEQSNGITQIGKAMNQLDTVTQENAAASEQAAASSQELAGQATVLNKVVEELRVAIKGSASA

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=262, Percent_Identity=42.7480916030534, Blast_Score=193, Evalue=2e-50,
Organism=Escherichia coli, GI1788194, Length=258, Percent_Identity=43.0232558139535, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI2367378, Length=235, Percent_Identity=45.1063829787234, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI1788195, Length=237, Percent_Identity=43.8818565400844, Blast_Score=180, Evalue=2e-46,
Organism=Escherichia coli, GI1789453, Length=267, Percent_Identity=35.5805243445693, Blast_Score=150, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 51173; Mature: 51173

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQLSLSQKMSLIVAILCAGIVGVAGVGLYNLKRVGDVVSNVTDVQFKSVVEALNLKDAF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HGQMIYERNYVLFYDNLEKRANNSAQIKKLDSGIRTIVADRMQVADATEKSSLEKFLTTY
CCCEEEECCEEEEECCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NRWSDNDLEIQKIMADADGHQKALGLISSVGRDTRLEGDKALDEILTHHQAQLEEQKKKS
HCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ADAISSTFQILIWTGSAVILLGVLLAAMTLRKMSAAISSVLRNLGENAFQVNHTATQIAT
HHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHH
ASQGLSQSATEQASSLEETVATIEELTAMVRINAENAASATDLAEGTRRSAEDGERKIQG
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHH
LLEAMKVIDQDSKKIQEITSVVDDLAFQTNLLALNAAVEAARAGEQGKGFAVVAEAVRTL
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
ALKSSDAAKDISNLINSSVERIQAGFERANESVDSLTEIVGSVKKVSSLNSEIASATSEQ
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SNGITQIGKAMNQLDTVTQENAAASEQAAASSQELAGQATVLNKVVEELRVAIKGSASA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKQLSLSQKMSLIVAILCAGIVGVAGVGLYNLKRVGDVVSNVTDVQFKSVVEALNLKDAF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HGQMIYERNYVLFYDNLEKRANNSAQIKKLDSGIRTIVADRMQVADATEKSSLEKFLTTY
CCCEEEECCEEEEECCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NRWSDNDLEIQKIMADADGHQKALGLISSVGRDTRLEGDKALDEILTHHQAQLEEQKKKS
HCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ADAISSTFQILIWTGSAVILLGVLLAAMTLRKMSAAISSVLRNLGENAFQVNHTATQIAT
HHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHH
ASQGLSQSATEQASSLEETVATIEELTAMVRINAENAASATDLAEGTRRSAEDGERKIQG
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHH
LLEAMKVIDQDSKKIQEITSVVDDLAFQTNLLALNAAVEAARAGEQGKGFAVVAEAVRTL
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
ALKSSDAAKDISNLINSSVERIQAGFERANESVDSLTEIVGSVKKVSSLNSEIASATSEQ
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SNGITQIGKAMNQLDTVTQENAAASEQAAASSQELAGQATVLNKVVEELRVAIKGSASA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]