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The map label for this gene is lysR [H]

Identifier: 42522634

GI number: 42522634

Start: 1024224

End: 1024994

Strand: Direct

Name: lysR [H]

Synonym: Bd1080

Alternate gene names: 42522634

Gene position: 1024224-1024994 (Clockwise)

Preceding gene: 42522632

Following gene: 42522635

Centisome position: 27.07

GC content: 49.81

Gene sequence:

>771_bases
GTGGAGCTCCTGGTAAGGGGTGTGCGCTCAATCAAGGCCACTCCCCAAGGCGAGGTTCTGTATGAGTACGCAAAAAAGAT
CATTCATCTGACCCAACAGGCTGAAATCGCCATTAAATCCATCGGGAATCAAATGAAGGGGCAGTTGCGAATTGGGACGC
TGAACTCTTTGGGCTTGCACGTAATGAGTCCCATTGTGGGACGTTTAATGCGCCACAATCCCGAGCTGACCCTGAAGATC
GAATACGATCGCGGGGAAGAGCTGATTAAGGGATACAAAAAAGGCCAGTACGATGTTCTGATTCTGCCCGACGTACAAAC
TGAGTTTGCGTCCGAGCTGGATAGCAGCGAGCAGAAGTTCCTTTTGAAGGAAGAAATGTGGCTTGTGGGTTCAAGTAAAG
ATGAAAAAATGCCCCAACAGATCATGGTGAAGGACATGGGAGCTTTTCCACTGGTGGATTTCACCGAAGAATTCCCGGCC
TTCTACAGCCAACTGCATGGCAAGATTCAGACCCAGGGGGCGAAGGTCACTTCGATCTTTGAGTCTTCCAACGTAGGGAC
CTTGAAGCGGGTGATTGAAGCGGGGTTGGGCTGGGGCTTTTTGCCGGCACACTCAATCAAGAAGCAAGTCCGTTCGGGCC
GCCTAAGTCGTGTGTACGTAAAAGACATGCACTACGAAATTGATCTGATGTTCTATTATAAAAAGAATTCCGACAGCCGT
GCTTTGGTCGAGGTTTTCTATCAGACCCTGGCTCAGCAGGAAAAAGGCTGA

Upstream 100 bases:

>100_bases
TGTCATCAGCGAAGGGAGCATGACTGCCGCGGCAGATAAGCTCTACCTGACTCAACCTGCGGTGTCTCAGCAGATTCGCA
ATCTGGAGGAAGATCTAGGT

Downstream 100 bases:

>100_bases
CCTTAGGTCCCATTAATAAGTGAGCCCTTCTGACCGAAAAGACTCTCAGATCATTTTCGTCAGAAGGGACGTCCATGAAA
AAAAGCTACTCAATTCAGGT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Nitrogen assimilation control protein [H]

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MELLVRGVRSIKATPQGEVLYEYAKKIIHLTQQAEIAIKSIGNQMKGQLRIGTLNSLGLHVMSPIVGRLMRHNPELTLKI
EYDRGEELIKGYKKGQYDVLILPDVQTEFASELDSSEQKFLLKEEMWLVGSSKDEKMPQQIMVKDMGAFPLVDFTEEFPA
FYSQLHGKIQTQGAKVTSIFESSNVGTLKRVIEAGLGWGFLPAHSIKKQVRSGRLSRVYVKDMHYEIDLMFYYKKNSDSR
ALVEVFYQTLAQQEKG

Sequences:

>Translated_256_residues
MELLVRGVRSIKATPQGEVLYEYAKKIIHLTQQAEIAIKSIGNQMKGQLRIGTLNSLGLHVMSPIVGRLMRHNPELTLKI
EYDRGEELIKGYKKGQYDVLILPDVQTEFASELDSSEQKFLLKEEMWLVGSSKDEKMPQQIMVKDMGAFPLVDFTEEFPA
FYSQLHGKIQTQGAKVTSIFESSNVGTLKRVIEAGLGWGFLPAHSIKKQVRSGRLSRVYVKDMHYEIDLMFYYKKNSDSR
ALVEVFYQTLAQQEKG
>Mature_256_residues
MELLVRGVRSIKATPQGEVLYEYAKKIIHLTQQAEIAIKSIGNQMKGQLRIGTLNSLGLHVMSPIVGRLMRHNPELTLKI
EYDRGEELIKGYKKGQYDVLILPDVQTEFASELDSSEQKFLLKEEMWLVGSSKDEKMPQQIMVKDMGAFPLVDFTEEFPA
FYSQLHGKIQTQGAKVTSIFESSNVGTLKRVIEAGLGWGFLPAHSIKKQVRSGRLSRVYVKDMHYEIDLMFYYKKNSDSR
ALVEVFYQTLAQQEKG

Specific function: Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation. Negative regulator of its own expression [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788297, Length=227, Percent_Identity=25.5506607929515, Blast_Score=64, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 29182; Mature: 29182

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELLVRGVRSIKATPQGEVLYEYAKKIIHLTQQAEIAIKSIGNQMKGQLRIGTLNSLGLH
CHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHH
VMSPIVGRLMRHNPELTLKIEYDRGEELIKGYKKGQYDVLILPDVQTEFASELDSSEQKF
HHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHCCCCEEEEEECCCHHHHHHHCCCCHHHH
LLKEEMWLVGSSKDEKMPQQIMVKDMGAFPLVDFTEEFPAFYSQLHGKIQTQGAKVTSIF
HHHHHHHEECCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHCCCCEEEEEC
ESSNVGTLKRVIEAGLGWGFLPAHSIKKQVRSGRLSRVYVKDMHYEIDLMFYYKKNSDSR
CCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCEEEEEEECCEEEEEEEEEECCCCCH
ALVEVFYQTLAQQEKG
HHHHHHHHHHHHHCCC
>Mature Secondary Structure
MELLVRGVRSIKATPQGEVLYEYAKKIIHLTQQAEIAIKSIGNQMKGQLRIGTLNSLGLH
CHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHH
VMSPIVGRLMRHNPELTLKIEYDRGEELIKGYKKGQYDVLILPDVQTEFASELDSSEQKF
HHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHCCCCEEEEEECCCHHHHHHHCCCCHHHH
LLKEEMWLVGSSKDEKMPQQIMVKDMGAFPLVDFTEEFPAFYSQLHGKIQTQGAKVTSIF
HHHHHHHEECCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHCCCCEEEEEC
ESSNVGTLKRVIEAGLGWGFLPAHSIKKQVRSGRLSRVYVKDMHYEIDLMFYYKKNSDSR
CCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCEEEEEEECCEEEEEEEEEECCCCCH
ALVEVFYQTLAQQEKG
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8458853 [H]