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The map label for this gene is etf-QO [H]

Identifier: 42522512

GI number: 42522512

Start: 892813

End: 894549

Strand: Direct

Name: etf-QO [H]

Synonym: Bd0945

Alternate gene names: 42522512

Gene position: 892813-894549 (Clockwise)

Preceding gene: 42522511

Following gene: 42522513

Centisome position: 23.6

GC content: 50.89

Gene sequence:

>1737_bases
ATGTCTGTATACGATCAACTGCCAGAAGGTGTAACACGCGAAACGATGGACGTGGATGTCCTGATCGTCGGTGGTGGTTC
CGCGGGCTTGTCCTGCGCTTTGCATCTGCAAAATCAAATTCAAAAACACAACGAAGACGTTGCTGCCGGTAAAAAACAGG
GCGAGCAAATTCCGGAACAGATGATCGTTGTTCTGGAAAAAGCTTCTGAAGTGGGCGCGCACAGTTTCTCGGGTGCGGTT
TTGAACCCGAAAGCATTGACTGAGCTTATTCCTAATTTCAAAGAAGAAGGCTGCCCGATTGACTCTGAAGTCAAAAAGGA
TGCGGTTTACTATCTGGGTTCTGACTTCTCTTTCAAACTGCCAATCACTCCTCCGCCGTTCCACAATGAAGGCAATTACA
TTGTCTCTTTGAGCAAGTTCAACCGCTGGTTGGGCACCAAGTGTGAAGAAAAAGGCATCAACATCTTCCCGGGCTTTGCT
GCGGTGGAAGCGTTGTATGAAGGCGATAAAATCGTCGGCGTTCGCACCGGTGACAAAGGCCGCGACAAACACGGCAATCC
AAAGGCGAACTTCGAGCCGGGTCTGATTCTGAAATCCAAAGTCGTGATCTTTGCCGAAGGGACTCGTGGTTCCCTGTTCC
GTCAGGTTGAAAAGAAATTGGACCTGCGCGCCGGCAAAAACAAAGAAGTCTTCGAAGAAGGCGTGAAGGAAATCATCCAG
ATGCCTCCGGGCACGGTGGAAGCTGGCCAGGTTATCCATACCATGGGCTTCCCGCTGTCCAAATCCATCGGTGGGACTTT
CATTTACACCATCCCAGGGGACAAGATCATCGTGGGTCTGGTGGCTTACTTAGACACCCAGGATCCATTGCTGGATCCAC
ACCGTGAACTGCAAAAACTGAAAACTCATCCGTTCCTGCAAAGCATGCTTAAAGGCGGTAAAGTCATCGCTTACGGCGGT
AAGACCCTGCCTGCGGGTGGCTGGTATTCCATGCCGAAGCTGTACGGTAACGGCTTTATGGTCTGCGGTGACTCTGCCAG
CATGGTGGACGTGCAGAAGCTAAAGGGTATCCACTTGGCGATGAAATCCGGCATGCAGGCGGCGGAAGCCGTTGTTGACG
GTTTGATCAAAGGTGGTGATTTCTCTGAGGAAGTGACCAAGGGGTATTCCGACCGTATTGAAGCGGGTTATGTAAAAACC
GAGCTTTATCGTGTTCGTAACTTCCACCAGGCGCTCAGCAAAGGGATGGTGGAAAGCATGCCTCTGTTGGCCCTTCAGGA
GCTGACCGGCGGCCGTGGTCTGCAGGATCCAATGCCGATTGACCATATCGACGCTGAAACCACTGAAAAAGTCCTGGATA
TCTGGGGTCCTTATGGCCTGGATCACGAGGACAACAAGCTCCCTAAAGCCGACGGGGAGCTGTTCTTTGATAAGCTTTCC
AGCGTTTACCTGACCGGGACCATGCACGACGAGGATTCCCCAAACCACCTTATTTTGAAGGATGGGGATATCTGCCGTAC
CGTATGTGAGCCTCAGTACAAATCACCATGTAATCATTTCTGCCCGGCGGCGGTTTATGAGATGGTGCCGTCTACAAAAG
AGGCAGGCAAGAAGGACTTACAAATCAATTATACGAACTGTATTCACTGCAAAACTTGTGATATTAAGTGCCCATTCGAA
AATATCGAGTGGACCGTTCCTGAAGGGGGCGGTGGACCACAATACCGCGAAACATAG

Upstream 100 bases:

>100_bases
CAAGCTGGCTCCGCAGGCGGAAGTCAAAGACGAGCCGATGGAAGAGTAGGGGCTCCAGCCCCGGGTTTTGAGTTTTTGTA
TTGAATTGAATGGAGAGAAT

Downstream 100 bases:

>100_bases
GAAGCCTGGCGTTGGGACTGGGCTTTCTTAACAAAGGAAAGGTCAGTCTCATGCCTCAGTTTTTTGCCTCCACAGCCCGT
GGACTTGTTGAACCCCTGGA

Product: electron transfer flavoprotein-ubiquinone oxidoreductase

Products: NA

Alternate protein names: ETF-QO; ETF-ubiquinone oxidoreductase; Electron-transferring-flavoprotein dehydrogenase; ETF dehydrogenase [H]

Number of amino acids: Translated: 578; Mature: 577

Protein sequence:

>578_residues
MSVYDQLPEGVTRETMDVDVLIVGGGSAGLSCALHLQNQIQKHNEDVAAGKKQGEQIPEQMIVVLEKASEVGAHSFSGAV
LNPKALTELIPNFKEEGCPIDSEVKKDAVYYLGSDFSFKLPITPPPFHNEGNYIVSLSKFNRWLGTKCEEKGINIFPGFA
AVEALYEGDKIVGVRTGDKGRDKHGNPKANFEPGLILKSKVVIFAEGTRGSLFRQVEKKLDLRAGKNKEVFEEGVKEIIQ
MPPGTVEAGQVIHTMGFPLSKSIGGTFIYTIPGDKIIVGLVAYLDTQDPLLDPHRELQKLKTHPFLQSMLKGGKVIAYGG
KTLPAGGWYSMPKLYGNGFMVCGDSASMVDVQKLKGIHLAMKSGMQAAEAVVDGLIKGGDFSEEVTKGYSDRIEAGYVKT
ELYRVRNFHQALSKGMVESMPLLALQELTGGRGLQDPMPIDHIDAETTEKVLDIWGPYGLDHEDNKLPKADGELFFDKLS
SVYLTGTMHDEDSPNHLILKDGDICRTVCEPQYKSPCNHFCPAAVYEMVPSTKEAGKKDLQINYTNCIHCKTCDIKCPFE
NIEWTVPEGGGGPQYRET

Sequences:

>Translated_578_residues
MSVYDQLPEGVTRETMDVDVLIVGGGSAGLSCALHLQNQIQKHNEDVAAGKKQGEQIPEQMIVVLEKASEVGAHSFSGAV
LNPKALTELIPNFKEEGCPIDSEVKKDAVYYLGSDFSFKLPITPPPFHNEGNYIVSLSKFNRWLGTKCEEKGINIFPGFA
AVEALYEGDKIVGVRTGDKGRDKHGNPKANFEPGLILKSKVVIFAEGTRGSLFRQVEKKLDLRAGKNKEVFEEGVKEIIQ
MPPGTVEAGQVIHTMGFPLSKSIGGTFIYTIPGDKIIVGLVAYLDTQDPLLDPHRELQKLKTHPFLQSMLKGGKVIAYGG
KTLPAGGWYSMPKLYGNGFMVCGDSASMVDVQKLKGIHLAMKSGMQAAEAVVDGLIKGGDFSEEVTKGYSDRIEAGYVKT
ELYRVRNFHQALSKGMVESMPLLALQELTGGRGLQDPMPIDHIDAETTEKVLDIWGPYGLDHEDNKLPKADGELFFDKLS
SVYLTGTMHDEDSPNHLILKDGDICRTVCEPQYKSPCNHFCPAAVYEMVPSTKEAGKKDLQINYTNCIHCKTCDIKCPFE
NIEWTVPEGGGGPQYRET
>Mature_577_residues
SVYDQLPEGVTRETMDVDVLIVGGGSAGLSCALHLQNQIQKHNEDVAAGKKQGEQIPEQMIVVLEKASEVGAHSFSGAVL
NPKALTELIPNFKEEGCPIDSEVKKDAVYYLGSDFSFKLPITPPPFHNEGNYIVSLSKFNRWLGTKCEEKGINIFPGFAA
VEALYEGDKIVGVRTGDKGRDKHGNPKANFEPGLILKSKVVIFAEGTRGSLFRQVEKKLDLRAGKNKEVFEEGVKEIIQM
PPGTVEAGQVIHTMGFPLSKSIGGTFIYTIPGDKIIVGLVAYLDTQDPLLDPHRELQKLKTHPFLQSMLKGGKVIAYGGK
TLPAGGWYSMPKLYGNGFMVCGDSASMVDVQKLKGIHLAMKSGMQAAEAVVDGLIKGGDFSEEVTKGYSDRIEAGYVKTE
LYRVRNFHQALSKGMVESMPLLALQELTGGRGLQDPMPIDHIDAETTEKVLDIWGPYGLDHEDNKLPKADGELFFDKLSS
VYLTGTMHDEDSPNHLILKDGDICRTVCEPQYKSPCNHFCPAAVYEMVPSTKEAGKKDLQINYTNCIHCKTCDIKCPFEN
IEWTVPEGGGGPQYRET

Specific function: Accepts electrons from ETF and reduces ubiquinone [H]

COG id: COG0644

COG function: function code C; Dehydrogenases (flavoproteins)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI119703746, Length=589, Percent_Identity=39.7283531409168, Blast_Score=385, Evalue=1e-107,
Organism=Escherichia coli, GI1787991, Length=339, Percent_Identity=26.2536873156342, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1786227, Length=397, Percent_Identity=25.4408060453401, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI87082155, Length=326, Percent_Identity=26.0736196319018, Blast_Score=100, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI25144720, Length=578, Percent_Identity=41.0034602076125, Blast_Score=389, Evalue=1e-108,
Organism=Saccharomyces cerevisiae, GI6324932, Length=591, Percent_Identity=37.5634517766497, Blast_Score=337, Evalue=4e-93,
Organism=Drosophila melanogaster, GI24652256, Length=581, Percent_Identity=40.1032702237522, Blast_Score=382, Evalue=1e-106,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR007859
- InterPro:   IPR003042 [H]

Pfam domain/function: PF05187 ETF_QO [H]

EC number: =1.5.5.1 [H]

Molecular weight: Translated: 63378; Mature: 63247

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVYDQLPEGVTRETMDVDVLIVGGGSAGLSCALHLQNQIQKHNEDVAAGKKQGEQIPEQ
CCHHHHCCCCCCCCCCEEEEEEECCCCCCCEEHHHHHHHHHHCCCHHHHHHHHHHHHHHH
MIVVLEKASEVGAHSFSGAVLNPKALTELIPNFKEEGCPIDSEVKKDAVYYLGSDFSFKL
HHHHHHHHHHHCCCCCCCCEECHHHHHHHHCCHHHCCCCCCHHHHCCEEEEECCCEEEEE
PITPPPFHNEGNYIVSLSKFNRWLGTKCEEKGINIFPGFAAVEALYEGDKIVGVRTGDKG
CCCCCCCCCCCCEEEEHHHHHHHHCCCHHHCCCEEECCHHHHHHHHCCCEEEEEECCCCC
RDKHGNPKANFEPGLILKSKVVIFAEGTRGSLFRQVEKKLDLRAGKNKEVFEEGVKEIIQ
CCCCCCCCCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
MPPGTVEAGQVIHTMGFPLSKSIGGTFIYTIPGDKIIVGLVAYLDTQDPLLDPHRELQKL
CCCCCCCCCCCHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCHHHHHHHH
KTHPFLQSMLKGGKVIAYGGKTLPAGGWYSMPKLYGNGFMVCGDSASMVDVQKLKGIHLA
HCCHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHCCCEEEECCCCCHHHHHHHCCHHHH
MKSGMQAAEAVVDGLIKGGDFSEEVTKGYSDRIEAGYVKTELYRVRNFHQALSKGMVESM
HHHCHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHC
PLLALQELTGGRGLQDPMPIDHIDAETTEKVLDIWGPYGLDHEDNKLPKADGELFFDKLS
HHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHC
SVYLTGTMHDEDSPNHLILKDGDICRTVCEPQYKSPCNHFCPAAVYEMVPSTKEAGKKDL
CEEEEEEECCCCCCCEEEEECCHHHHHHCCCCCCCCHHHCCHHHHHHHCCCHHHCCCCCE
QINYTNCIHCKTCDIKCPFENIEWTVPEGGGGPQYRET
EEEECEEEEEEECCCCCCCCCCEEECCCCCCCCCCCCC
>Mature Secondary Structure 
SVYDQLPEGVTRETMDVDVLIVGGGSAGLSCALHLQNQIQKHNEDVAAGKKQGEQIPEQ
CHHHHCCCCCCCCCCEEEEEEECCCCCCCEEHHHHHHHHHHCCCHHHHHHHHHHHHHHH
MIVVLEKASEVGAHSFSGAVLNPKALTELIPNFKEEGCPIDSEVKKDAVYYLGSDFSFKL
HHHHHHHHHHHCCCCCCCCEECHHHHHHHHCCHHHCCCCCCHHHHCCEEEEECCCEEEEE
PITPPPFHNEGNYIVSLSKFNRWLGTKCEEKGINIFPGFAAVEALYEGDKIVGVRTGDKG
CCCCCCCCCCCCEEEEHHHHHHHHCCCHHHCCCEEECCHHHHHHHHCCCEEEEEECCCCC
RDKHGNPKANFEPGLILKSKVVIFAEGTRGSLFRQVEKKLDLRAGKNKEVFEEGVKEIIQ
CCCCCCCCCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
MPPGTVEAGQVIHTMGFPLSKSIGGTFIYTIPGDKIIVGLVAYLDTQDPLLDPHRELQKL
CCCCCCCCCCCHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCHHHHHHHH
KTHPFLQSMLKGGKVIAYGGKTLPAGGWYSMPKLYGNGFMVCGDSASMVDVQKLKGIHLA
HCCHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHCCCEEEECCCCCHHHHHHHCCHHHH
MKSGMQAAEAVVDGLIKGGDFSEEVTKGYSDRIEAGYVKTELYRVRNFHQALSKGMVESM
HHHCHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHC
PLLALQELTGGRGLQDPMPIDHIDAETTEKVLDIWGPYGLDHEDNKLPKADGELFFDKLS
HHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHC
SVYLTGTMHDEDSPNHLILKDGDICRTVCEPQYKSPCNHFCPAAVYEMVPSTKEAGKKDL
CEEEEEEECCCCCCCEEEEECCHHHHHHCCCCCCCCHHHCCHHHHHHHCCCHHHCCCCCE
QINYTNCIHCKTCDIKCPFENIEWTVPEGGGGPQYRET
EEEECEEEEEEECCCCCCCCCCEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9294455 [H]