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The map label for this gene is pilQ [H]

Identifier: 42522439

GI number: 42522439

Start: 813406

End: 815586

Strand: Direct

Name: pilQ [H]

Synonym: Bd0867

Alternate gene names: 42522439

Gene position: 813406-815586 (Clockwise)

Preceding gene: 42522438

Following gene: 42522440

Centisome position: 21.5

GC content: 52.64

Gene sequence:

>2181_bases
ATGAACGGATTCATTAGATTAGTAATCCTGAGCGCAATGATTGCCTCTCTGACTTCCTGTGCAAGCCGTCCGGTTGAAGA
CGATCTGTCTTTGGATGGCATGGATTCCTCTGCGGATGTGACATCTGCAGACGAAAGCGCTCCAGCGGCTGACTCAGCCT
CTGATGATTTCGCAGAATTCGATGAAATCGACAATCAACAACCCGCGCAAGCTGAATCTCAAGCAGCTCCTGCCGATGAC
CAGGACCTGGCCATCGAAGAGGAAGTGAACGAGGCCGGCGGACAGGAACAAGTGGCCGATGCGCCGGCTCCTGCTCCGGA
AGAAACCAGCCCGACGGAAGATCCGTTTGCAGACAGTTCTGTAGCGGATGTTCCTGCTCAAACTCCAGAGCCGACGGTGA
CCGAAACCACGCCAGATCCATTTGCGGATCAGCCGCCGGTTTCCGAGCCGGCACCGGCTCCGGTGACTGAAACGATTGCC
GCTGTTCCATCCGGAGCTCCGGCAAATATTACGGACCTTAAATTCCGCGCCAATGAAACGGGTGGGACTGTGATCGTGCA
GGGGGATCGTCCTTTGACGTACACCACCCGCACAAATCCTGATCTGCGCCAGTTCATCATTGAAGTGGACAACGCCAACT
TGCCAGACCGTTTGAAACGCTCTTTGAACACCAAAGACATCAAAGGCAGCGTGGGTGCTATTGATGCTTATCAAAATCCG
GGTTCTGCAACAGCGCGCTTTGTGATCCAGATGCGCGAAGGTTTGGGCGAGCCGATGGTTCAGCAAGAAGGCAACAGCCT
TCTGATCGTGGCCAGCGGATCTGCTCCGGCAGAGGCGATGGAAGTGACAGATGTCAGCACGGCGATGGAAGACAACAACA
TCCTGCCAAGCCAGAATCTGACAGAGTTCCTTGCCGGCAACACCAAATTCTACGGTAAAAAGATCTCTATCGAGACCAGC
AACATGGACATCCGTGACGCTTTGAACTTCATCACGGAAGAGTCCGGCGTGAACATGGTGATCTCTGAAGACGTTAAAGG
TGCAGTCAGTCTGAAGCTGCGTCAGGTTCCTTGGGACCAGGCGCTGGTTGTGATCATGAAAGCGAAAAAGCTGGGCTACA
CCCGTCAGGGCAACGTATTGCGTATCGCTCCACTTCAGGATCTGAAAGCGGAAGAAGATGATGCAACGAAACTGGCACAG
GCCAGAAAGAATCTGGAACCTTTGAAGGTTCGCATGTTCCCAGTCAGCTACGCGAAAGTCGACGAGCTTGAAAAGAAGAT
CAAAGACTTCCTGGGCGACCGTGGCCGTGTGGTCGGTGACGTTCGTACAAATGCTTTGGTGGTGACTGATATCGAAGAAA
ACCTGGAAAGAGCAGCTCGTCTGATCGCCAGCCTAGATACACAGCCTGCGCAAGTGTCCATCGAGGGTAAAATCGTCGAG
GCGAAAGAAAGCTTCACCCGCAATATCGGTGTAAACTGGAGTGCGACGGGTGCGCCAATCAAGCTGGGTTCCACGGCTCG
TGGTCCGGTGAACATGAATCCGTCCTTCAACGTGAATCAGAGCGCGGCGGGTTCTTCCGGTGCTTTGAACTTCAACCTGA
ATGTGGGGACTTTGGATATCTTTGGTACTTTGTCAGCGGCCCTAGCCCTGAACGAAAGCGAAGAGCAGGTTAAGATCATC
TCCGCTCCGCGTATCATGACTCTGTCCAATGAAAAAGCTGACATCAATCAGACGACGGAAGTTCCGGTTCGTCAGGTGAC
TCAGAACGGGACAGCCACTCAGGAAACGTTCCAGTTCAAGCCATTGACACTGAAACTTGAGGTGACTCCGCAGGTAACGG
CGGATGGATCTGTTATCATGAAAGTACTGGTTAACAGACAATTCCGTGGTGCTGACGTGTCCAGTGCCGGTCAGGGCGCC
TTTGCGGTGAACAGCCGTGAAGCCAACACCCGTGTTCTGGTGAAAAACGGTCAGACTGCGGTTATTGGTGGTATCTATCA
AAGTGATGCCACAGACGGTGAAGTGGGTGTTCCTTGGTTCCGCGAATTGCCATTCGTAAGTTATCTGTTTAAGACCAAGA
ACATCTCCAAGGAAAAGTCTGAGTTGTTGATCTTCCTGACCCCAAGAATTATGGGTCAGATCGACAACAACGCAGGCAAT
CCGACAACCACTGACTTCTAA

Upstream 100 bases:

>100_bases
AGGTTGTTGTCGTGGAAACGAAATACGACGACGGCAAAGCCTTCAAAGAGTCACGCATTATGGAGTTGAAAAAATAGTTA
TCTTTTAAGAGGAGGAACTA

Downstream 100 bases:

>100_bases
CGAGGAGGACCCATGCGACACTGGAAAGTTTTAATGTTGGCATTGGTGGCAGTGGCCCTGCCCAATTGTGCGCAGGAGGC
CGGTCAGCTTTCAACATCAG

Product: fimbrial assembly protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 726; Mature: 726

Protein sequence:

>726_residues
MNGFIRLVILSAMIASLTSCASRPVEDDLSLDGMDSSADVTSADESAPAADSASDDFAEFDEIDNQQPAQAESQAAPADD
QDLAIEEEVNEAGGQEQVADAPAPAPEETSPTEDPFADSSVADVPAQTPEPTVTETTPDPFADQPPVSEPAPAPVTETIA
AVPSGAPANITDLKFRANETGGTVIVQGDRPLTYTTRTNPDLRQFIIEVDNANLPDRLKRSLNTKDIKGSVGAIDAYQNP
GSATARFVIQMREGLGEPMVQQEGNSLLIVASGSAPAEAMEVTDVSTAMEDNNILPSQNLTEFLAGNTKFYGKKISIETS
NMDIRDALNFITEESGVNMVISEDVKGAVSLKLRQVPWDQALVVIMKAKKLGYTRQGNVLRIAPLQDLKAEEDDATKLAQ
ARKNLEPLKVRMFPVSYAKVDELEKKIKDFLGDRGRVVGDVRTNALVVTDIEENLERAARLIASLDTQPAQVSIEGKIVE
AKESFTRNIGVNWSATGAPIKLGSTARGPVNMNPSFNVNQSAAGSSGALNFNLNVGTLDIFGTLSAALALNESEEQVKII
SAPRIMTLSNEKADINQTTEVPVRQVTQNGTATQETFQFKPLTLKLEVTPQVTADGSVIMKVLVNRQFRGADVSSAGQGA
FAVNSREANTRVLVKNGQTAVIGGIYQSDATDGEVGVPWFRELPFVSYLFKTKNISKEKSELLIFLTPRIMGQIDNNAGN
PTTTDF

Sequences:

>Translated_726_residues
MNGFIRLVILSAMIASLTSCASRPVEDDLSLDGMDSSADVTSADESAPAADSASDDFAEFDEIDNQQPAQAESQAAPADD
QDLAIEEEVNEAGGQEQVADAPAPAPEETSPTEDPFADSSVADVPAQTPEPTVTETTPDPFADQPPVSEPAPAPVTETIA
AVPSGAPANITDLKFRANETGGTVIVQGDRPLTYTTRTNPDLRQFIIEVDNANLPDRLKRSLNTKDIKGSVGAIDAYQNP
GSATARFVIQMREGLGEPMVQQEGNSLLIVASGSAPAEAMEVTDVSTAMEDNNILPSQNLTEFLAGNTKFYGKKISIETS
NMDIRDALNFITEESGVNMVISEDVKGAVSLKLRQVPWDQALVVIMKAKKLGYTRQGNVLRIAPLQDLKAEEDDATKLAQ
ARKNLEPLKVRMFPVSYAKVDELEKKIKDFLGDRGRVVGDVRTNALVVTDIEENLERAARLIASLDTQPAQVSIEGKIVE
AKESFTRNIGVNWSATGAPIKLGSTARGPVNMNPSFNVNQSAAGSSGALNFNLNVGTLDIFGTLSAALALNESEEQVKII
SAPRIMTLSNEKADINQTTEVPVRQVTQNGTATQETFQFKPLTLKLEVTPQVTADGSVIMKVLVNRQFRGADVSSAGQGA
FAVNSREANTRVLVKNGQTAVIGGIYQSDATDGEVGVPWFRELPFVSYLFKTKNISKEKSELLIFLTPRIMGQIDNNAGN
PTTTDF
>Mature_726_residues
MNGFIRLVILSAMIASLTSCASRPVEDDLSLDGMDSSADVTSADESAPAADSASDDFAEFDEIDNQQPAQAESQAAPADD
QDLAIEEEVNEAGGQEQVADAPAPAPEETSPTEDPFADSSVADVPAQTPEPTVTETTPDPFADQPPVSEPAPAPVTETIA
AVPSGAPANITDLKFRANETGGTVIVQGDRPLTYTTRTNPDLRQFIIEVDNANLPDRLKRSLNTKDIKGSVGAIDAYQNP
GSATARFVIQMREGLGEPMVQQEGNSLLIVASGSAPAEAMEVTDVSTAMEDNNILPSQNLTEFLAGNTKFYGKKISIETS
NMDIRDALNFITEESGVNMVISEDVKGAVSLKLRQVPWDQALVVIMKAKKLGYTRQGNVLRIAPLQDLKAEEDDATKLAQ
ARKNLEPLKVRMFPVSYAKVDELEKKIKDFLGDRGRVVGDVRTNALVVTDIEENLERAARLIASLDTQPAQVSIEGKIVE
AKESFTRNIGVNWSATGAPIKLGSTARGPVNMNPSFNVNQSAAGSSGALNFNLNVGTLDIFGTLSAALALNESEEQVKII
SAPRIMTLSNEKADINQTTEVPVRQVTQNGTATQETFQFKPLTLKLEVTPQVTADGSVIMKVLVNRQFRGADVSSAGQGA
FAVNSREANTRVLVKNGQTAVIGGIYQSDATDGEVGVPWFRELPFVSYLFKTKNISKEKSELLIFLTPRIMGQIDNNAGN
PTTTDF

Specific function: Required for type IV pilus biogenesis and competence. Could function as a pore for exit of the pilus but also as a channel for entry of heme and antimicrobial agents and uptake of transforming DNA [H]

COG id: COG4796

COG function: function code U; Type II secretory pathway, component HofQ

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI1789793, Length=404, Percent_Identity=29.4554455445545, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI87082242, Length=338, Percent_Identity=28.698224852071, Blast_Score=103, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001775
- InterPro:   IPR005644
- InterPro:   IPR013355
- InterPro:   IPR011662
- InterPro:   IPR004846
- InterPro:   IPR004845 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N; PF07660 STN [H]

EC number: NA

Molecular weight: Translated: 77806; Mature: 77806

Theoretical pI: Translated: 4.22; Mature: 4.22

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGFIRLVILSAMIASLTSCASRPVEDDLSLDGMDSSADVTSADESAPAADSASDDFAEF
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
DEIDNQQPAQAESQAAPADDQDLAIEEEVNEAGGQEQVADAPAPAPEETSPTEDPFADSS
HHCCCCCCCCHHHCCCCCCCCCCCHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCCCCCCC
VADVPAQTPEPTVTETTPDPFADQPPVSEPAPAPVTETIAAVPSGAPANITDLKFRANET
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCEEEEEEEECCC
GGTVIVQGDRPLTYTTRTNPDLRQFIIEVDNANLPDRLKRSLNTKDIKGSVGAIDAYQNP
CCEEEEECCCCEEEEECCCHHHHHHEEEECCCCCCHHHHHCCCCCCCCCCCCEEECCCCC
GSATARFVIQMREGLGEPMVQQEGNSLLIVASGSAPAEAMEVTDVSTAMEDNNILPSQNL
CCHHHHHHHHHHHCCCCCHHHHCCCEEEEEECCCCCCHHEEEHHHHHHHCCCCCCCCCCH
TEFLAGNTKFYGKKISIETSNMDIRDALNFITEESGVNMVISEDVKGAVSLKLRQVPWDQ
HHHHCCCCEEECEEEEEEECCCCHHHHHHHHHCCCCCEEEEECCCCCEEEEEEECCCCCC
ALVVIMKAKKLGYTRQGNVLRIAPLQDLKAEEDDATKLAQARKNLEPLKVRMFPVSYAKV
EEEEEEEHHHCCCCCCCCEEEEECHHHCCCCCCHHHHHHHHHCCCCCEEEEEEECCHHHH
DELEKKIKDFLGDRGRVVGDVRTNALVVTDIEENLERAARLIASLDTQPAQVSIEGKIVE
HHHHHHHHHHHCCCCCEEEEECCCEEEEECHHHHHHHHHHHHHHCCCCCCEEEEEEEEEE
AKESFTRNIGVNWSATGAPIKLGSTARGPVNMNPSFNVNQSAAGSSGALNFNLNVGTLDI
CHHHHHHHCCCCEECCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCEEHH
FGTLSAALALNESEEQVKIISAPRIMTLSNEKADINQTTEVPVRQVTQNGTATQETFQFK
HHHHHHHHEECCCCCEEEEEECCEEEEECCCCCCCCCCCCCCHHHHHCCCCCCCCEEEEC
PLTLKLEVTPQVTADGSVIMKVLVNRQFRGADVSSAGQGAFAVNSREANTRVLVKNGQTA
CEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCEEEEECCCEE
VIGGIYQSDATDGEVGVPWFRELPFVSYLFKTKNISKEKSELLIFLTPRIMGQIDNNAGN
EEEEEEECCCCCCCCCCCHHHHCCHHHHHHHHCCCCCCCCCEEEEECHHHHHEECCCCCC
PTTTDF
CCCCCC
>Mature Secondary Structure
MNGFIRLVILSAMIASLTSCASRPVEDDLSLDGMDSSADVTSADESAPAADSASDDFAEF
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
DEIDNQQPAQAESQAAPADDQDLAIEEEVNEAGGQEQVADAPAPAPEETSPTEDPFADSS
HHCCCCCCCCHHHCCCCCCCCCCCHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCCCCCCC
VADVPAQTPEPTVTETTPDPFADQPPVSEPAPAPVTETIAAVPSGAPANITDLKFRANET
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCEEEEEEEECCC
GGTVIVQGDRPLTYTTRTNPDLRQFIIEVDNANLPDRLKRSLNTKDIKGSVGAIDAYQNP
CCEEEEECCCCEEEEECCCHHHHHHEEEECCCCCCHHHHHCCCCCCCCCCCCEEECCCCC
GSATARFVIQMREGLGEPMVQQEGNSLLIVASGSAPAEAMEVTDVSTAMEDNNILPSQNL
CCHHHHHHHHHHHCCCCCHHHHCCCEEEEEECCCCCCHHEEEHHHHHHHCCCCCCCCCCH
TEFLAGNTKFYGKKISIETSNMDIRDALNFITEESGVNMVISEDVKGAVSLKLRQVPWDQ
HHHHCCCCEEECEEEEEEECCCCHHHHHHHHHCCCCCEEEEECCCCCEEEEEEECCCCCC
ALVVIMKAKKLGYTRQGNVLRIAPLQDLKAEEDDATKLAQARKNLEPLKVRMFPVSYAKV
EEEEEEEHHHCCCCCCCCEEEEECHHHCCCCCCHHHHHHHHHCCCCCEEEEEEECCHHHH
DELEKKIKDFLGDRGRVVGDVRTNALVVTDIEENLERAARLIASLDTQPAQVSIEGKIVE
HHHHHHHHHHHCCCCCEEEEECCCEEEEECHHHHHHHHHHHHHHCCCCCCEEEEEEEEEE
AKESFTRNIGVNWSATGAPIKLGSTARGPVNMNPSFNVNQSAAGSSGALNFNLNVGTLDI
CHHHHHHHCCCCEECCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCEEHH
FGTLSAALALNESEEQVKIISAPRIMTLSNEKADINQTTEVPVRQVTQNGTATQETFQFK
HHHHHHHHEECCCCCEEEEEECCEEEEECCCCCCCCCCCCCCHHHHHCCCCCCCCEEEEC
PLTLKLEVTPQVTADGSVIMKVLVNRQFRGADVSSAGQGAFAVNSREANTRVLVKNGQTA
CEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCEEEEECCCEE
VIGGIYQSDATDGEVGVPWFRELPFVSYLFKTKNISKEKSELLIFLTPRIMGQIDNNAGN
EEEEEEECCCCCCCCCCCHHHHCCHHHHHHHHCCCCCCCCCEEEEECHHHHHEECCCCCC
PTTTDF
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10710307 [H]