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The map label for this gene is trmB

Identifier: 42521984

GI number: 42521984

Start: 346843

End: 347472

Strand: Direct

Name: trmB

Synonym: Bd0370

Alternate gene names: 42521984

Gene position: 346843-347472 (Clockwise)

Preceding gene: 42521983

Following gene: 42521985

Centisome position: 9.17

GC content: 48.41

Gene sequence:

>630_bases
CTGGCGTTGAATGGCGAATATGCACACGTGGCTTTCGATGAACTGCGTGCGCCGCTGAACAAGGGCAAGTGGCGTTCGGA
CGTCTTCAAAGCCGATGCGGCCATGCCGCTGGATGTGGAAGTGGGCACTGGCAATGGGACTTATTTTGCTCATCACGCAA
AGACCCATTCCGACCGTCTGTTGGTGGGTCTGGAGCTGAAATACAAACCTCTGATTCAATCCATCCGTCGCGCCGTGAAC
GCGGGCTGCAAAAATGCGGCGATCACGCGTTTCCATGCCTTCAATATTGATCATCTTTTCGCTGAGGGTGAAATCGACAA
CGTCTACATCCATTTCCCGGATCCATGGACGTCTCCGAAAAAGCCTAAAAACCGCTTCGTGTGCAAAGAGAATCTGGAGT
TGTTGTTCCGTCTGCAAAAGCCAGGTTCTTTCATCAATTTCAAAACTGATTCTTTGGTGTACTTCCTGTGGGCGATGGAT
GAAATCCGTCAGTCCCCGTACAAGATCATTTTTGAAACTCAGGATCTGCACAATTCGGACATGAAAGATCAGAACTTCGA
AACGGCTTTTGAGAAAATCTTCCTGCGTGAAGGAATCAAAATCAATTTCGTCAGACTTCAGAAGATCTAA

Upstream 100 bases:

>100_bases
GATGACCCGGCTCCGACTAATCAAGGGACCCATGACAGATCAGGCTCTTCGCAGACAAATTAACATCACCAAAGACCTTC
CCAACCAGAACGCCTACACC

Downstream 100 bases:

>100_bases
GGTTCTAGGTCCAGCGTTAAAAGGCAAAATTCAAAATTAGTCCCGCACTCGGGATACAATGGGCCCATAGAAGGAGAATT
CTATGGGTTTTTTATTAAAG

Product: hypothetical protein

Products: NA

Alternate protein names: tRNA(m7G46)-methyltransferase

Number of amino acids: Translated: 209; Mature: 208

Protein sequence:

>209_residues
MALNGEYAHVAFDELRAPLNKGKWRSDVFKADAAMPLDVEVGTGNGTYFAHHAKTHSDRLLVGLELKYKPLIQSIRRAVN
AGCKNAAITRFHAFNIDHLFAEGEIDNVYIHFPDPWTSPKKPKNRFVCKENLELLFRLQKPGSFINFKTDSLVYFLWAMD
EIRQSPYKIIFETQDLHNSDMKDQNFETAFEKIFLREGIKINFVRLQKI

Sequences:

>Translated_209_residues
MALNGEYAHVAFDELRAPLNKGKWRSDVFKADAAMPLDVEVGTGNGTYFAHHAKTHSDRLLVGLELKYKPLIQSIRRAVN
AGCKNAAITRFHAFNIDHLFAEGEIDNVYIHFPDPWTSPKKPKNRFVCKENLELLFRLQKPGSFINFKTDSLVYFLWAMD
EIRQSPYKIIFETQDLHNSDMKDQNFETAFEKIFLREGIKINFVRLQKI
>Mature_208_residues
ALNGEYAHVAFDELRAPLNKGKWRSDVFKADAAMPLDVEVGTGNGTYFAHHAKTHSDRLLVGLELKYKPLIQSIRRAVNA
GCKNAAITRFHAFNIDHLFAEGEIDNVYIHFPDPWTSPKKPKNRFVCKENLELLFRLQKPGSFINFKTDSLVYFLWAMDE
IRQSPYKIIFETQDLHNSDMKDQNFETAFEKIFLREGIKINFVRLQKI

Specific function: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA

COG id: COG0220

COG function: function code R; Predicted S-adenosylmethionine-dependent methyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. TrmB family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TRMB_BDEBA (Q6MQU0)

Other databases:

- EMBL:   BX842646
- RefSeq:   NP_967364.1
- ProteinModelPortal:   Q6MQU0
- GeneID:   2734260
- GenomeReviews:   BX842601_GR
- KEGG:   bba:Bd0370
- NMPDR:   fig|264462.1.peg.334
- OMA:   LRNKPWA
- BioCyc:   BBAC264462:BD0370-MONOMER
- BRENDA:   2.1.1.33
- HAMAP:   MF_01057
- InterPro:   IPR003358
- PANTHER:   PTHR23417:SF1

Pfam domain/function: PF02390 Methyltransf_4

EC number: =2.1.1.33

Molecular weight: Translated: 24222; Mature: 24091

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: NA

Important sites: BINDING 40-40 BINDING 65-65 BINDING 114-114 BINDING 150-150

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALNGEYAHVAFDELRAPLNKGKWRSDVFKADAAMPLDVEVGTGNGTYFAHHAKTHSDRL
CCCCCCEEEEEHHHHHCCHHCCCCHHHHHHCCCCCCEEEEEECCCCEEEEEECCCCCCEE
LVGLELKYKPLIQSIRRAVNAGCKNAAITRFHAFNIDHLFAEGEIDNVYIHFPDPWTSPK
EEEEEECCHHHHHHHHHHHHCCCCCCEEEEEEEECCHHEEECCCCCEEEEECCCCCCCCC
KPKNRFVCKENLELLFRLQKPGSFINFKTDSLVYFLWAMDEIRQSPYKIIFETQDLHNSD
CCCCCEEECCCCEEEEEECCCCCEEEEECCCEEEEEEEHHHHHCCCEEEEEEECCCCCCC
MKDQNFETAFEKIFLREGIKINFVRLQKI
CCCCHHHHHHHHHHHHCCCEEEEEEEECC
>Mature Secondary Structure 
ALNGEYAHVAFDELRAPLNKGKWRSDVFKADAAMPLDVEVGTGNGTYFAHHAKTHSDRL
CCCCCEEEEEHHHHHCCHHCCCCHHHHHHCCCCCCEEEEEECCCCEEEEEECCCCCCEE
LVGLELKYKPLIQSIRRAVNAGCKNAAITRFHAFNIDHLFAEGEIDNVYIHFPDPWTSPK
EEEEEECCHHHHHHHHHHHHCCCCCCEEEEEEEECCHHEEECCCCCEEEEECCCCCCCCC
KPKNRFVCKENLELLFRLQKPGSFINFKTDSLVYFLWAMDEIRQSPYKIIFETQDLHNSD
CCCCCEEECCCCEEEEEECCCCCEEEEECCCEEEEEEEHHHHHCCCEEEEEEECCCCCCC
MKDQNFETAFEKIFLREGIKINFVRLQKI
CCCCHHHHHHHHHHHHCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA