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The map label for this gene is prkA [H]

Identifier: 42521854

GI number: 42521854

Start: 214170

End: 216245

Strand: Direct

Name: prkA [H]

Synonym: Bd0228

Alternate gene names: 42521854

Gene position: 214170-216245 (Clockwise)

Preceding gene: 42521853

Following gene: 42521855

Centisome position: 5.66

GC content: 48.27

Gene sequence:

>2076_bases
ATGGCCTCTAAGTTTGATCTGCATTCACTGGTCGCCAACTGGCAAAACTCAAGCACTCATGCCAAAGAGCATTGGAGTGG
CACCTTCGAGGAATATCTCGACCTGGTAAAACAAAATCCGAAAATCACGCGAAACGCCTATCAGCGCATGTATGACATGA
TCGTTGAAGAAGGCACTGAAACGTACATTGATTTCAAAAAAGAAGTCATTCGCTACAAGTTCTTCGACGACGTTCATAAC
AATGGCAAAGACGCGGTCTTCGGCCTGGATGTGCAGTTGATGAAATTGGTGAATGTTCTGAAAGCGGCGGCCCTGGGTTA
CGGAACCGAGAAACGTGTGATCCTGCTGCACGGCCCGGTGGGAAGTGCGAAATCCACCATCTGCCGCATGCTGAAAAAGG
GTCTTGAGCGCTACTCGCACACCAAGCAGGGTGCGGTGTACACCTTTGAATGGATCGATGAAAAACTCGAACTTGATGGT
TTGCTGGGTAAAGGTGTGAAGGTCTTCCATTCCCCAATGAATGAAGAACCTTTGCTGCTGATTCCGGAAGAGCTTCGTTC
CACGGTTTATGACTCTATCAACAAAGGCCAGGAAGGCAGCTTCCGTGTGCACGTGGATGGCGAATTAAGCCCGCCTTCTC
GTTTTATCTTTAAAGCCCTGATGGAAAAATACGACGGCAACCTGATGCAGGTTCTGTCGCACGTGCGTGTGAAAAGATTG
TTCATCTCTGAAGCGGACCGTGTGGGTATTGGTACCTTCCAGCCGAAAGATGAAAAGAATCAGGACTCCACCGAGCTTAC
GGGTGATATCAACTATCGTAAAATTGCCGAATACGGATCTGATTCTGATCCGCGCGCCTTTAACTTTGACGGGGAGTTCA
ACGTCGCCAATCGTGGGATGATTGAATTCGTCGAGGTTCTGAAGCTGGATGTGGCCTTCTTGTACGATCTGTTGGGGGCT
TCGCAAGAACACCGTGTGAAACCTAAAAAGTTCGCACAGACCCATATCGATGAAGTGATCATCGGTCACACGAATGAACC
GGAATACCGTCGTTTGCAAGACAACGAATTCATGGAAGCTCTTCGTGACCGTACCGTGAAGATCGACATTCCTTACATCA
CGCGCTGGAGAGATGAAATCAACATTTACAAACGCGACTTCAATTCCCAGAAAGTGCGTGGAATCAGTATTGCCCCGCAC
ACGGTTGAAATGGCCGCAATGTGGGCGATTCTGACCCGTCTGGAAAAACCGAAGAAAGCCAATTTGACCCGTTTGCAGAA
ACTGAAACTGTATAACGGTAAAACGCTGCCGAACTATACTGAAGACAACGTTCGCGAGCTTCGTAAAGAAACTGTGCGTG
AGGGGCTTGAGGGTATTTCAGCCCGTTATATCCAGGATAAACTTTCCAACGCCCTGGTGGCGGCTCAGCAGTCCAACAAA
GGATCTGTGAATCCGTTCATGGTGTTTAAAGAGCTTGAATCCGGTTTGAAAAGTCACTCGTTGATCGCCAACGAAGAGCT
GAAGACCGAGTTTAAGGAACTTCTGGGTGTGGTCATGCAGGAGTACGAGGAAATCATCAAAGCTGAGGTGCAAAGAGCCA
TCAGTGCCGATGAAAGTGCCATGCAGCGACTGTGTGCCAACTATATTGATAACGTCAAAGCCTATACGCAAAGAGAACGA
GTTCGCAATCAGTTCACCGGCAACGACGAGGAGCCGGATGAGCGTCTGATGCGATCTATCGAAGAGAAGATCGAGATCCC
TGAGTCCCGCAAGGATGATTTCCGTCGCGAGATCATGAACTACATCGGGGCCCTGGCTTTGGAAGGCAAGAAGTTCAACT
ACAAGATGAACGAACGCCTGCATAAAGCCATCGAGTTGAAACTCTTCGAGGATCAGAAAGACAGCATCAAGCTGACCACT
TTGGTAAGCAACGTTGCTGACAAAGACACTCAAGAGAAGATTGATATTGTAAAAACCCGTCTCATCAAGGACTTCGGTTA
CGATGAAATCTCTGCTACGGATGTATTGCATTACGTGGCAAGTATCTTCGCCCGAGGGGACGTAAAGAATAAATAA

Upstream 100 bases:

>100_bases
TTCAAAGCAATACAACTAAATTAAAAAACTCGTTAACCGTCTAGTAATGAGGCATACTCTAACAGAGTAGGTGTGTCACC
AATCACCTTGGGGAGAGAAT

Downstream 100 bases:

>100_bases
TGTCGATACGCGAAGACCATAACAGATTCAGAGAGATCGTTAAAGGCAAGGTCAAAGAGGATCTGCGCAAGTACGTCTCT
CAGGGCGAAATGATCGGGAA

Product: serine protein kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 691; Mature: 690

Protein sequence:

>691_residues
MASKFDLHSLVANWQNSSTHAKEHWSGTFEEYLDLVKQNPKITRNAYQRMYDMIVEEGTETYIDFKKEVIRYKFFDDVHN
NGKDAVFGLDVQLMKLVNVLKAAALGYGTEKRVILLHGPVGSAKSTICRMLKKGLERYSHTKQGAVYTFEWIDEKLELDG
LLGKGVKVFHSPMNEEPLLLIPEELRSTVYDSINKGQEGSFRVHVDGELSPPSRFIFKALMEKYDGNLMQVLSHVRVKRL
FISEADRVGIGTFQPKDEKNQDSTELTGDINYRKIAEYGSDSDPRAFNFDGEFNVANRGMIEFVEVLKLDVAFLYDLLGA
SQEHRVKPKKFAQTHIDEVIIGHTNEPEYRRLQDNEFMEALRDRTVKIDIPYITRWRDEINIYKRDFNSQKVRGISIAPH
TVEMAAMWAILTRLEKPKKANLTRLQKLKLYNGKTLPNYTEDNVRELRKETVREGLEGISARYIQDKLSNALVAAQQSNK
GSVNPFMVFKELESGLKSHSLIANEELKTEFKELLGVVMQEYEEIIKAEVQRAISADESAMQRLCANYIDNVKAYTQRER
VRNQFTGNDEEPDERLMRSIEEKIEIPESRKDDFRREIMNYIGALALEGKKFNYKMNERLHKAIELKLFEDQKDSIKLTT
LVSNVADKDTQEKIDIVKTRLIKDFGYDEISATDVLHYVASIFARGDVKNK

Sequences:

>Translated_691_residues
MASKFDLHSLVANWQNSSTHAKEHWSGTFEEYLDLVKQNPKITRNAYQRMYDMIVEEGTETYIDFKKEVIRYKFFDDVHN
NGKDAVFGLDVQLMKLVNVLKAAALGYGTEKRVILLHGPVGSAKSTICRMLKKGLERYSHTKQGAVYTFEWIDEKLELDG
LLGKGVKVFHSPMNEEPLLLIPEELRSTVYDSINKGQEGSFRVHVDGELSPPSRFIFKALMEKYDGNLMQVLSHVRVKRL
FISEADRVGIGTFQPKDEKNQDSTELTGDINYRKIAEYGSDSDPRAFNFDGEFNVANRGMIEFVEVLKLDVAFLYDLLGA
SQEHRVKPKKFAQTHIDEVIIGHTNEPEYRRLQDNEFMEALRDRTVKIDIPYITRWRDEINIYKRDFNSQKVRGISIAPH
TVEMAAMWAILTRLEKPKKANLTRLQKLKLYNGKTLPNYTEDNVRELRKETVREGLEGISARYIQDKLSNALVAAQQSNK
GSVNPFMVFKELESGLKSHSLIANEELKTEFKELLGVVMQEYEEIIKAEVQRAISADESAMQRLCANYIDNVKAYTQRER
VRNQFTGNDEEPDERLMRSIEEKIEIPESRKDDFRREIMNYIGALALEGKKFNYKMNERLHKAIELKLFEDQKDSIKLTT
LVSNVADKDTQEKIDIVKTRLIKDFGYDEISATDVLHYVASIFARGDVKNK
>Mature_690_residues
ASKFDLHSLVANWQNSSTHAKEHWSGTFEEYLDLVKQNPKITRNAYQRMYDMIVEEGTETYIDFKKEVIRYKFFDDVHNN
GKDAVFGLDVQLMKLVNVLKAAALGYGTEKRVILLHGPVGSAKSTICRMLKKGLERYSHTKQGAVYTFEWIDEKLELDGL
LGKGVKVFHSPMNEEPLLLIPEELRSTVYDSINKGQEGSFRVHVDGELSPPSRFIFKALMEKYDGNLMQVLSHVRVKRLF
ISEADRVGIGTFQPKDEKNQDSTELTGDINYRKIAEYGSDSDPRAFNFDGEFNVANRGMIEFVEVLKLDVAFLYDLLGAS
QEHRVKPKKFAQTHIDEVIIGHTNEPEYRRLQDNEFMEALRDRTVKIDIPYITRWRDEINIYKRDFNSQKVRGISIAPHT
VEMAAMWAILTRLEKPKKANLTRLQKLKLYNGKTLPNYTEDNVRELRKETVREGLEGISARYIQDKLSNALVAAQQSNKG
SVNPFMVFKELESGLKSHSLIANEELKTEFKELLGVVMQEYEEIIKAEVQRAISADESAMQRLCANYIDNVKAYTQRERV
RNQFTGNDEEPDERLMRSIEEKIEIPESRKDDFRREIMNYIGALALEGKKFNYKMNERLHKAIELKLFEDQKDSIKLTTL
VSNVADKDTQEKIDIVKTRLIKDFGYDEISATDVLHYVASIFARGDVKNK

Specific function: Unknown

COG id: COG2766

COG function: function code T; Putative Ser protein kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prkA family [H]

Homologues:

Organism=Escherichia coli, GI1788083, Length=666, Percent_Identity=26.5765765765766, Blast_Score=182, Evalue=5e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013153
- InterPro:   IPR010650
- InterPro:   IPR016230 [H]

Pfam domain/function: PF08298 AAA_PrkA; PF06798 PrkA [H]

EC number: NA

Molecular weight: Translated: 79785; Mature: 79654

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASKFDLHSLVANWQNSSTHAKEHWSGTFEEYLDLVKQNPKITRNAYQRMYDMIVEEGTE
CCCCHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCH
TYIDFKKEVIRYKFFDDVHNNGKDAVFGLDVQLMKLVNVLKAAALGYGTEKRVILLHGPV
HHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCCCCEEEEECCC
GSAKSTICRMLKKGLERYSHTKQGAVYTFEWIDEKLELDGLLGKGVKVFHSPMNEEPLLL
CCHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHCCHHHHHCCCCCCCEEE
IPEELRSTVYDSINKGQEGSFRVHVDGELSPPSRFIFKALMEKYDGNLMQVLSHVRVKRL
ECHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
FISEADRVGIGTFQPKDEKNQDSTELTGDINYRKIAEYGSDSDPRAFNFDGEFNVANRGM
HHHCCCCCCCCCCCCCCCCCCCCCCEECCCCHHHHHHCCCCCCCCEECCCCCCCCCCCCH
IEFVEVLKLDVAFLYDLLGASQEHRVKPKKFAQTHIDEVIIGHTNEPEYRRLQDNEFMEA
HHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHEEECCCCCCHHHHCCHHHHHHH
LRDRTVKIDIPYITRWRDEINIYKRDFNSQKVRGISIAPHTVEMAAMWAILTRLEKPKKA
HHCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCCC
NLTRLQKLKLYNGKTLPNYTEDNVRELRKETVREGLEGISARYIQDKLSNALVAAQQSNK
CHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GSVNPFMVFKELESGLKSHSLIANEELKTEFKELLGVVMQEYEEIIKAEVQRAISADESA
CCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
MQRLCANYIDNVKAYTQRERVRNQFTGNDEEPDERLMRSIEEKIEIPESRKDDFRREIMN
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
YIGALALEGKKFNYKMNERLHKAIELKLFEDQKDSIKLTTLVSNVADKDTQEKIDIVKTR
HHHHHHCCCCCCCCHHHHHHHHHHHHHEECCCCCCEEHHHHHHHHHCCCHHHHHHHHHHH
LIKDFGYDEISATDVLHYVASIFARGDVKNK
HHHHCCCCHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
ASKFDLHSLVANWQNSSTHAKEHWSGTFEEYLDLVKQNPKITRNAYQRMYDMIVEEGTE
CCCHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCH
TYIDFKKEVIRYKFFDDVHNNGKDAVFGLDVQLMKLVNVLKAAALGYGTEKRVILLHGPV
HHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCCCCEEEEECCC
GSAKSTICRMLKKGLERYSHTKQGAVYTFEWIDEKLELDGLLGKGVKVFHSPMNEEPLLL
CCHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHCCHHHHHCCCCCCCEEE
IPEELRSTVYDSINKGQEGSFRVHVDGELSPPSRFIFKALMEKYDGNLMQVLSHVRVKRL
ECHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
FISEADRVGIGTFQPKDEKNQDSTELTGDINYRKIAEYGSDSDPRAFNFDGEFNVANRGM
HHHCCCCCCCCCCCCCCCCCCCCCCEECCCCHHHHHHCCCCCCCCEECCCCCCCCCCCCH
IEFVEVLKLDVAFLYDLLGASQEHRVKPKKFAQTHIDEVIIGHTNEPEYRRLQDNEFMEA
HHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHEEECCCCCCHHHHCCHHHHHHH
LRDRTVKIDIPYITRWRDEINIYKRDFNSQKVRGISIAPHTVEMAAMWAILTRLEKPKKA
HHCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCCC
NLTRLQKLKLYNGKTLPNYTEDNVRELRKETVREGLEGISARYIQDKLSNALVAAQQSNK
CHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GSVNPFMVFKELESGLKSHSLIANEELKTEFKELLGVVMQEYEEIIKAEVQRAISADESA
CCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
MQRLCANYIDNVKAYTQRERVRNQFTGNDEEPDERLMRSIEEKIEIPESRKDDFRREIMN
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
YIGALALEGKKFNYKMNERLHKAIELKLFEDQKDSIKLTTLVSNVADKDTQEKIDIVKTR
HHHHHHCCCCCCCCHHHHHHHHHHHHHEECCCCCCEEHHHHHHHHHCCCHHHHHHHHHHH
LIKDFGYDEISATDVLHYVASIFARGDVKNK
HHHHCCCCHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]